The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Regulation of miRNA expression during neural cell specification
Abstract
MicroRNA (miRNA) are a newly recognized class of small, noncoding RNA molecules that participate in the developmental control of gene expression. We have studied the regulation of a set of highly expressed neural miRNA during mouse brain development. Temporal control is a characteristic of miRNA regulation in C. elegans and Drosophila, and is also prominent in the embryonic brain. We observed significant differences in the onset and magnitude of induction for individual miRNAs. Comparing expression in cultures of embryonic neurons and astrocytes we found marked lineage specificity for each of the miRNA in our study. Two of the most highly expressed miRNA in adult brain were preferentially expressed in neurons (mir-124, mir-128). In contrast, mir-23, a miRNA previously implicated in neural specification, was restricted to astrocytes. mir-26 and mir-29 were more strongly expressed in astrocytes than neurons, others were more evenly distributed (mir-9, mir-125). Lineage specificity was further explored using reporter constructs for two miRNA of particular interest (mir-125 and mir-128). miRNA-mediated suppression of both reporters was observed after transfection of the reporters into neurons but not astrocytes. miRNA were strongly induced during neural differentiation of embryonic stem cells, suggesting the validity of the stem cell model for studying miRNA regulation in neural development.
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In the citing paper
“The decrease in miR-23 levels can lead to the accumulation of Hes1 during retinal acid-induced neural differentiation in NT2 cells, which in turn affects neural differentiation.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“miR-23 has the ability to affect neural differentiation.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“Hes1 is also directly targeted by miR-124, and the knockdown of miR-124 levels mediated by locked nucleic acids is similar to the effect of miR-23 inhibition.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“It indicates that the regulation of neural development by miR-23 is probably achieved through the combined action of other miRNAs.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“A basic helix-loop-helix transcriptional repressor, named Hes1, is an authentic target of miR-23.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“miR-23 is specifically expressed in astrocytes of the adult brain and is one of the miRNAs that are highly expressed in neurons during brain development.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“The expression level of Hes1 increases, ultimately hindering neuronal differentiation of P19 cells induced by the retinoic acid [[129], [130], [131]].”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“Notably, three miRNAs (miR-23, miR-26 and miR-29) that are found in oligodendrocyte lineage cells were previously described as enriched in astrocytes (Smirnova et al., 2005).”
From Identification of Dynamically Regulated MicroRNA and mRNA Networks in Developing Oligodendrocytes (2008) · cites this paper as Smirnova et al., 2005
In the citing paper
“miR-124 is known to be expressed in the CNS by neuronal cells23,39–41.”
From MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway (2011) · cites this paper as [23]
In the citing paper
“Such expression in neurons of the adult brain is shared with mouse miR-124 [30].”
From MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system (2007) · cites this paper as [30]
In the citing paper
“This profile is one of the best conserved miRNA patterns, as a similar restriction to mature neurons is seen for mouse and fly miR-124 [12,30].”
From MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system (2007) · cites this paper as [30]
In the citing paper
“miR-23 is involved in neuronal specification, and miR-146a implicated in the prevention of neuroligin 1-dependent synaptogenesis, and both were enriched in astrocytes compared to neurons [54, 67].”
From Differential RNA packaging into small extracellular vesicles by neurons and astrocytes (2021) · cites this paper as [67]
In the citing paper
“being prominently observed in differentiating neuronal cells29,31”
From MiR-128-3p – a gray eminence of the human central nervous system (2024) · cites this paper as [31]
Citations
Cites
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948
The functions of animal microRNAs
Ambros, V. (2004) · Nature · doi:10.1038/nature02871 · Cited by 10,728
MicroRNAs: small RNAs with a big role in gene regulation
He, L., & Hannon, G. J. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1379 · Cited by 7,118
Prediction of Mammalian MicroRNA Targets
Lewis, B. P., Shih, I.-H., Jones-Rhoades, M. W., Bartel, D. P., & Burge, C. B. (2003) · Cell · doi:10.1016/s0092-8674(03)01018-3 · Cited by 5,199
Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M., Rai, K., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242606799 · Cited by 5,111
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
Reinhart, B. J., Slack, F. J., Basson, M., Pasquinelli, A. E., Bettinger, J. C., Rougvie, A. E., Horvitz, H. R., & Ruvkun, G. (2000) · Nature · doi:10.1038/35002607 · Cited by 4,989
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
Calin, G. A., Sevignani, C., Dumitru, C. D., Hyslop, T., Noch, E., Yendamuri, S., Shimizu, M., Rattan, S., Bullrich, F., Negrini, M., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0307323101 · Cited by 4,096
John, B., Enright, A. J., Aravin, A., Tuschl, T., Sander, C., & Marks, D. S. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020363 · Cited by 3,796
MicroRNA targets in Drosophila
Enright, A. J., John, B., Gaul, U., Tuschl, T., Sander, C., & Marks, D. S. (2003) · Genome Biology · doi:10.1186/gb-2003-5-1-r1 · Cited by 3,597
Cited by
Sorted by citations
Items 401–500 of 715
Bame, M., McInnis, M. G., & O’Shea, K. S. (2020) · Stem Cells and Development · doi:10.1089/scd.2020.0046 · Cited by 25
Mojtahedi, S., Kordi, M. R., Hosseini, S. E., Omran, S. F., & Soleimani, M. (2013) · Cell Biology International · doi:10.1002/cbin.10022 · Cited by 26
Potenza, N., Papa, U., & Russo, A. (2009) · Cell Biology International · doi:10.1016/j.cellbi.2009.04.002 · Cited by 26
Functions of the bone morphogenetic protein signaling pathway through microRNAs (Review)
Hata, A., & Kang, H. (2015) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2015.2060 · Cited by 26
Expression of microRNAs during embryonic development of Xenopus tropicalis
McGann, J. C., & Harland, R. M. (2008) · Gene Expression Patterns · doi:10.1016/j.gep.2008.03.002 · Cited by 25
Guo, L., Sun, B., Sang, F., Wang, W., & Lu, Z. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007944 · Cited by 26
Anitha, A., & Thanseem, I. (2015) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-22671-2_5 · Cited by 25
microRNA-449 is a putative regulator of choroid plexus development and function
Redshaw, N. M., Wheeler, G., Hajihosseini, M. K., & Dalmay, T. (2008) · Brain Research · doi:10.1016/j.brainres.2008.11.020 · Cited by 26
A Perspective on the Role of microRNA-128 Regulation in Mental and Behavioral Disorders
Ching, A.-S., & Ahmad-Annuar, A. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00465 · Cited by 24
Optimization of Feline Immunodeficiency Virus Vectors for RNA Interference
Harper, S. Q., Staber, P. D., Beck, C. R., Fineberg, S. K., Stein, C. S., Ochoa, D., & Davidson, B. L. (2006) · Journal of Virology · doi:10.1128/jvi.00958-06 · Cited by 26
Extracellular Vesicles, Stem Cells and the Role of miRNAs in Neurodegeneration
MARATOVICH, B. A., Al-Yozbaki, M., George, A., Niyazova, R. Y., Sharipov, K. O., Byrne, L. J., & Wilson, C. M. (2021) · Current Neuropharmacology · doi:10.2174/1570159x19666210817150141 · Cited by 27
(2011) · Europe PMC (PubMed Central) · Cited by 25
Krupp, D. R., Xu, P., Thomas, S., Dellinger, A. E., Etchevers, H., Vekemans, M. J. J., Gilbert, J. R., Speer, M. C., Ashley‐Koch, A. E., & Gregory, S. G. (2012) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.23040 · Cited by 25
Exploratory study of sport-related concussion effects on peripheral micro-RNA expression
Svingos, A., Asken, B., Bauer, R., Dekosky, S., Hromas, G. A., Jaffee, M. S., Hayes, R., & Clugston, J. (2019) · Brain Injury · doi:10.1080/02699052.2019.1573379 · Cited by 25
Kobayashi, M., Benakis, C., Anderson, C. J., Moore, M. J., Poon, C., Uekawa, K., Dyke, J. P., Fak, J. J., Mele, A., Park, C. Y., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.06.075 · Cited by 25
Keasey, M. P., Scott, H. L., Bantounas, I., Uney, J. B., & Kelly, S. (2016) · Journal of Molecular Neuroscience · doi:10.1007/s12031-016-0740-9 · Cited by 24
Yoshizawa, S., Umezu, T., Saitoh, Y., Gotoh, M., Akahane, D., Kobayashi, C., Ohyashiki, J. H., & Ohyashiki, K. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092493 · Cited by 24
Tan, Z., Li, W., Cheng, X., Zhu, Q., & Zhang, X. (2022) · Biomolecules · doi:10.3390/biom13010018 · Cited by 25
MicroRNA in situ hybridization in the human entorhinal and transentorhinal cortex
Nelson, P. T. (2010) · Frontiers in Human Neuroscience · doi:10.3389/neuro.09.007.2010 · Cited by 24
NDRG2 promoted secreted miR-375 in microvesicles shed from M1 microglia, which induced neuron damage
Tang, L., Wu, Y., Fang, C., Qü, P., & Gao, Z.-L. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.11.098 · Cited by 24
Quintero, H., Gomez-Montalvo, A. I., & Lamas, M. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.12.025 · Cited by 24
Walker, S. E., Spencer, G. E., Necakov, A., & Carlone, R. L. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092741 · Cited by 25
XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way
Huang, R., Zhu, L., & Zhang, Y. (2020) · Cancer Cell International · doi:10.1186/s12935-020-01500-8 · Cited by 24
Maatouk, D. M., & Harfe, B. D. (2006) · The Scientific World JOURNAL · doi:10.1100/tsw.2006.313 · Cited by 24
Simple and highly specific targeting of resident microglia with adeno‐associated virus
Serrano, C., Cananzi, S., Shen, T., Wang, L.-L., & Zhang, C.-L. (2024) · iScience · doi:10.1016/j.isci.2024.110706 · Cited by 23
MicroRNA-regulated transgene expression systems for gene therapy and virotherapy
Sakurai, F. (2011) · Frontiers in bioscience · doi:10.2741/3861 · Cited by 23
Zheng, Y., Huang, Z., Xu, J., Hou, K., Yu, Y., Lv, S., Chen, L., Li, Y., Quan, C., & Chi, G. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02345-6 · Cited by 24
Potential role of miRNAs and their inhibitors in glioma treatment
Asadi-Moghaddam, K., Chiocca, E. A., & Lawler, S. E. (2010) · Expert Review of Anticancer Therapy · doi:10.1586/era.10.168 · Cited by 23
Tsetsarkin, K. A., Liu, G., Shen, K., & Pletnev, A. G. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw061 · Cited by 23
Lifespan and reproduction in brain-specific miR-29-knockdown mouse
Takeda, T., & Tanabe, H. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.02.055 · Cited by 23
Wang, Z., Pang, L., Zhao, H., Song, L., Wang, Y., Sun, Q., Guo, C., Wang, B., Qin, X., & Pan, A. (2016) · Acta Histochemica · doi:10.1016/j.acthis.2016.04.001 · Cited by 23
Wei, H., Wang, C., Zhang, C., Li, P., Wang, F., & Zhang, Z. (2010) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2010.04.007 · Cited by 23
Fujiwara, W., Kato, Y., Hayashi, M., Sugishita, Y., Okumura, S., Yoshinaga, M., Ishiguro, T., Yamada, R., Ueda, S., Harada, M., et al. (2018) · Journal of Cardiology · doi:10.1016/j.jjcc.2018.06.004 · Cited by 23
The experimental study of miRNA in pituitary adenomas.
Liang, S., Chen, L., Huang, H., & Dashi, Z. (2013) · PubMed · doi:10.5137/1019-5149.jtn.7425-12.1 · Cited by 22
Wang, C., Qiao, X., Zhang, Z., & Li, C. (2020) · Bioscience Reports · doi:10.1042/bsr20182121 · Cited by 21
The expression and functional roles of microRNAs in stem cell differentiation
Shim, J., & Nam, J. (2016) · BMB Reports · doi:10.5483/bmbrep.2016.49.1.217 · Cited by 22
Goustard, B., Koch, M., Lavialle, M., & Heberden, C. (2012) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2012.08.001 · Cited by 20
Jo, M.-H., Ali, B. A., Al-Khedhairy, A. A., Lee, C. H., Kim, B., Haam, S., Huh, Y., Ko, H. Y., & Kim, S. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.05.057 · Cited by 22
Luchting, B., Heyn, J., Hinske, L. C., & Azad, S. C. (2016) · Spine · doi:10.1097/brs.0000000000001763 · Cited by 23
Unveiling of miRNA Expression Patterns in Purkinje Cells During Development
Pieczora, L., Stracke, L., Vorgerd, M., Hahn, S. A., Theiß, C., & Theis, V. (2016) · The Cerebellum · doi:10.1007/s12311-016-0814-9 · Cited by 22
Epigenetic cerebellar diseases
Serrano, M. (2018) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64189-2.00015-9 · Cited by 22
Chen, H., Qian, K., Tang, Z. P., Xing, B.-Z., Chen, H., Liu, N., Huang, X., & Zhang, S. (2009) · Neurological Research · doi:10.1179/174313209x455691 · Cited by 22
Funahashi, H., Izawa, H., Hirashiki, A., Cheng, X. W., Inden, Y., Nomura, M., & Murohara, T. (2011) · Journal of Cardiology · doi:10.1016/j.jjcc.2011.01.009 · Cited by 22
Wang, J., Huang, Q., Ji, D., & Wang, X. (2019) · 3 Biotech · doi:10.1007/s13205-019-1914-2 · Cited by 21
Common microRNA regulated pathways in Alzheimer’s and Parkinson’s disease
Awuson-David, B., Williams, A. C., Wright, B. C., Hill, L. J., & Pietro, V. D. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1228927 · Cited by 21
miRNAs Highlights in Stem and Cancer Cells
Martignani, E., Miretti, S., Accornero, P., & Baratta, M. (2011) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955711797655371 · Cited by 21
Vuokila, N., Gupta, S. D., Huusko, R., Tohka, J., Puhakka, N., & Pitkänen, A. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.02.045 · Cited by 21
Role of microRNA Pathway in Mental Retardation
Qurashi, A., Chang, S., & Jin, P. (2007) · The Scientific World JOURNAL · doi:10.1100/tsw.2007.208 · Cited by 21
miRNA profiling of bilateral rat hippocampal CA3 by deep sequencing
Shinohara, Y., Yahagi, K., Kawano, M., Nishiyori, H., Kawazu, C., Suzuki, N., Manabe, R.-I., & Hirase, H. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.05.004 · Cited by 22
Zheng, L., Zhang, J., Yu, S., Ding, Z., Song, H., Wang, Y., & Li, Y. (2020) · BioMed Research International · doi:10.1155/2020/5205142 · Cited by 20
miR-124 disinhibits neurite outgrowth in an inflammatory environment
Hartmann, H., Höhne, K., Rist, E., Louw, A., & Schlosshauer, B. (2015) · Cell and Tissue Research · doi:10.1007/s00441-015-2183-y · Cited by 20
Smalheiser, N. R. (2008) · Biology Direct · doi:10.1186/1745-6150-3-44 · Cited by 20
Bautista, W., Rash, J. E., Vanderpool, K. G., Yasumura, T., & Nagy, J. I. (2013) · European Journal of Neuroscience · doi:10.1111/ejn.12450 · Cited by 20
Zou, H., Shao, C., Zhou, Q.-Y., Zhu, G., Shi, K., Braddock, M., Huang, D., & Zheng, M. (2015) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/17474124.2016.1116382 · Cited by 20
Gillet, V., Hunting, D. J., & Takser, L. (2016) · Current Environmental Health Reports · doi:10.1007/s40572-016-0093-0 · Cited by 20
Guo, Q., Zhang, J., Zheng, Z., Li, X., Wang, F., & Liu, S. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.29043 · Cited by 19
Small ncRNA Expression and Regulation Under Hypoxia in Neural Progenitor Cells
Liu, Z., Yang, G., Zhao, T., Cao, G., Xiong, L., Xia, W., Huang, X. H., Wu, L., Wu, K., Fan, M., et al. (2010) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-010-9556-2 · Cited by 19
Lee, H., Farhanullah, Lee, J., Jajoo, R., Kong, S.-Y., Shin, J.-Y., Kim, J., Lee, J., Lee, J., & Kim, H. (2015) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5b00243 · Cited by 20
MicroRNA-Mediated Reprogramming of Somatic Cells into Neural Stem Cells or Neurons
Yang, H., Zhang, L., An, J., Zhang, Q., Liu, C., He, B., & Hao, D. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0115-9 · Cited by 19
Unravelling Structure, Localization, and Genetic Crosstalk of KLF3 in Human Breast Cancer
Khan, K., Safi, S., Abbas, A., Badshah, Y., Dilshad, E., Rafiq, M., Zahra, K., & Shabbir, M. (2020) · BioMed Research International · doi:10.1155/2020/1354381 · Cited by 19
microRNA Expression Profiling of Propofol-Treated Developing Rat Hippocampal Astrocytes
Sun, W., & Pei, L. (2015) · DNA and Cell Biology · doi:10.1089/dna.2015.2831 · Cited by 19
Trivedi, S., & Ramakrishna, G. (2009) · International Journal of Neuroscience · doi:10.1080/00207450903139788 · Cited by 19
Kang, E., Jia, Y., Wang, J., Wang, G., Chen, H., Chen, X., Ye, Y., Zhang, X., Su, X., Wang, J., et al. (2022) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13845 · Cited by 19
Hafizi, M., Atashi, A., Bakhshandeh, B., Kabiri, M., Nadri, S., Hajihosseini, R., & Soleimani, M. (2012) · Biochemical Genetics · doi:10.1007/s10528-012-9553-x · Cited by 18
Uziel, O., Yosef, N., Sharan, R., Ruppin, E., Kupiec, M., Kushnir, M., Beery, E., Cohen-Diker, T., Nordenberg, J., & Lahav, M. (2014) · Genomics · doi:10.1016/j.ygeno.2014.10.013 · Cited by 18
Mukherjee, S., Akbar, I., Bhagat, R., Hazra, B., Bhattacharyya, A., Seth, P., Roy, D., & Basu, A. (2019) · mSphere · doi:10.1128/msphere.00588-19 · Cited by 17
Zhou, C., Li, S., Qiu, N., Sun, P., Hamblin, M. H., Dixon, C. E., Chen, J., & Yin, K. (2024) · JCI Insight · doi:10.1172/jci.insight.178650 · Cited by 17
Magnetic resonance beacon to detect intracellular microRNA during neurogenesis
Lee, J., Jin, Y. A., Ko, H. Y., Lee, Y. S., Heo, H., Cho, S., & Kim, S. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.11.033 · Cited by 17
Ba, Y., Liu, Y., Li, C., Zhu, Y., & Xing, W. (2020) · OncoTargets and Therapy · doi:10.2147/ott.s217087 · Cited by 17
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Laneve, P., & Caffarelli, E. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00275 · Cited by 17
Genetic and functional analyses of the gene encoding synaptophysin in schizophrenia
Shen, Y., Tsai, H.-M., Ruan, J., Liao, Y., Chen, S.-F., & Chen, C. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.01.028 · Cited by 18
miR-3099 promotes neurogenesis and inhibits astrogliogenesis during murine neural development
Abidin, S. Z., Fam, S.-Z., Chong, C., Abdullah, S., Cheah, P.-S., Nordin, N., & Ling, K. (2019) · Gene · doi:10.1016/j.gene.2019.02.014 · Cited by 17
Nervi, C., & Grignani, F. (2014) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-94-017-9050-5_8 · Cited by 17
Liao, K., Niu, F., Hu, G., & Buch, S. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.984375 · Cited by 16
Liu, J., Wang, L., Su, Z., Wu, W. H., Cai, X., Li, D., Hou, J., Pei, D., & Pan, G. (2014) · The FASEB Journal · doi:10.1096/fj.13-249342 · Cited by 16
Cheng, R., Zhang, G., Bai, Y., Zhang, F., & Zhang, G. (2021) · Cell Cycle · doi:10.1080/15384101.2021.1924958 · Cited by 16
RetractedMorris, J. K., Chomyk, A. M., Song, P., Parker, N., Deckard, S. A., Trapp, B. D., Pimplikar, S. W., & Dutta, R. (2015) · Invertebrate Neuroscience · doi:10.1007/s10158-015-0180-1 · Cited by 17
p38α controls self‐renewal and fate decision of neurosphere‐forming cells in adult hippocampus
Yoshioka, K., Namiki, K., SUDO, T., & Kasuya, Y. (2015) · FEBS Open Bio · doi:10.1016/j.fob.2015.05.001 · Cited by 15
Roles of microRNAs and their targets in cancer
Stefani, G. (2007) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.7.12.1833 · Cited by 16
Locked Nucleic Acid: Properties and Therapeutic Aspects
Koch, T., Rosenbohm, C., Hansen, H. F., Hansen, B. R., Straarup, E. M., & Kauppinen, S. (2008) · Royal Society of Chemistry eBooks · doi:10.1039/9781847558275-00103 · Cited by 16
Kopcho, S., McDew‐White, M., Naushad, W., Mohan, M., & Okeoma, C. M. (2023) · Viruses · doi:10.3390/v15030622 · Cited by 15
Peredo, J., Villacé, P., Ortı́n, J., & de Lucas, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113704 · Cited by 15
Sivakumaran, T. A., Resendes, B. L., Robertson, N. G., Giersch, A. B. S., & Morton, C. C. (2006) · Journal of the Association for Research in Otolaryngology · doi:10.1007/s10162-006-0032-0 · Cited by 15
Regulation of connexin 36 expression during development
Song, J., Wang, Y., Fontes, J. D., & Belousov, A. B. (2012) · Neuroscience Letters · doi:10.1016/j.neulet.2012.01.075 · Cited by 15
Epigenetic regulation of early neural fate commitment
Qiao, Y., Yang, X., & Jing, N. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2125-6 · Cited by 15
microRNAs in Autism Spectrum Disorders
Vasu, M. M., Sumitha, P. S., Parakkal, R., Thanseem, I., & Anitha, A. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666191105120901 · Cited by 15
Yang, X., & Liu, R. (2022) · Bioengineered · doi:10.1080/21655979.2022.2034565 · Cited by 15
microRNA Profiling as Tool for Developmental Neurotoxicity Testing (DNT)
Smirnova, L., Seiler, A. E. M., & Luch, A. (2015) · Current Protocols in Toxicology · doi:10.1002/0471140856.tx2009s64 · Cited by 15
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Kiel, K., Król, S. K., Bronisz, A., & Godlewski, J. (2024) · Molecular Therapy Nucleic Acids · doi:10.1016/j.omtn.2024.102141 · Cited by 15
Insight into the role of microRNAs in brain tumors (Review)
Catania, A. (2011) · International Journal of Oncology · doi:10.3892/ijo.2011.1305 · Cited by 15
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“In recent years, Kriegel et al reveal that the miR-29 family, including miR‑29A , miR‑29B‑1 , miR‑29B‑2 and miR‑29C (43), is found to be enriched in astrocytes (44).”
Background
Metadata
- Authors
- Smirnova, L., Gräfe, A., Seiler, A., Schumacher, S., Nitsch, R., & Wulczyn, F. G.
- Affiliations
- Charité – Universitätsmedizin Berlin (DE)
- German Federal Institute for Risk Assessment (BfR) (DE)
- Corresponding author
- Wulczyn, F. Gregory
- Venue
- European Journal of Neuroscience
- Publisher
- Wiley
- Published
- 2005-03
- Volume
- 21
- Issue
- 6
- Pages
- 1469-1477
- ISSN
- 0953-816X (ISSN-L)
- 1460-9568
- OpenAlex
- W2116641097
- Cited by
- 707
- References
- 55
- Citations by year
- 2026: 5 · 2025: 11 · 2024: 13 · 2023: 23 · 2022: 22 · 2021: 34 · 2020: 27 · 2019: 29 · 2018: 30 · 2017: 20 · 2016: 37 · 2015: 51 · 2014: 50 · 2013: 52 · 2012: 54
- FWCI
- 11.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- OpenAgrar (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- microRNA, brain development, miRNA expression regulation, astrocytes, embryonic neurons, miR-124, miR-128, miR-125, miR-23, miR-26, miR-29, miR-9, embryonic stem cell differentiation, temporal gene expression
- MeSH terms
- Animals, Animals, Newborn, Cell Differentiation, Cell Line, Neurons, Stem Cells, Gene Expression Regulation, Developmental, MicroRNAs, Mice
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