The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Regulation of miRNA expression during neural cell specification
Abstract
MicroRNA (miRNA) are a newly recognized class of small, noncoding RNA molecules that participate in the developmental control of gene expression. We have studied the regulation of a set of highly expressed neural miRNA during mouse brain development. Temporal control is a characteristic of miRNA regulation in C. elegans and Drosophila, and is also prominent in the embryonic brain. We observed significant differences in the onset and magnitude of induction for individual miRNAs. Comparing expression in cultures of embryonic neurons and astrocytes we found marked lineage specificity for each of the miRNA in our study. Two of the most highly expressed miRNA in adult brain were preferentially expressed in neurons (mir-124, mir-128). In contrast, mir-23, a miRNA previously implicated in neural specification, was restricted to astrocytes. mir-26 and mir-29 were more strongly expressed in astrocytes than neurons, others were more evenly distributed (mir-9, mir-125). Lineage specificity was further explored using reporter constructs for two miRNA of particular interest (mir-125 and mir-128). miRNA-mediated suppression of both reporters was observed after transfection of the reporters into neurons but not astrocytes. miRNA were strongly induced during neural differentiation of embryonic stem cells, suggesting the validity of the stem cell model for studying miRNA regulation in neural development.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The decrease in miR-23 levels can lead to the accumulation of Hes1 during retinal acid-induced neural differentiation in NT2 cells, which in turn affects neural differentiation.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“miR-23 has the ability to affect neural differentiation.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“Hes1 is also directly targeted by miR-124, and the knockdown of miR-124 levels mediated by locked nucleic acids is similar to the effect of miR-23 inhibition.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“It indicates that the regulation of neural development by miR-23 is probably achieved through the combined action of other miRNAs.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“A basic helix-loop-helix transcriptional repressor, named Hes1, is an authentic target of miR-23.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“miR-23 is specifically expressed in astrocytes of the adult brain and is one of the miRNAs that are highly expressed in neurons during brain development.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“The expression level of Hes1 increases, ultimately hindering neuronal differentiation of P19 cells induced by the retinoic acid [[129], [130], [131]].”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“Notably, three miRNAs (miR-23, miR-26 and miR-29) that are found in oligodendrocyte lineage cells were previously described as enriched in astrocytes (Smirnova et al., 2005).”
From Identification of Dynamically Regulated MicroRNA and mRNA Networks in Developing Oligodendrocytes (2008) · cites this paper as Smirnova et al., 2005
In the citing paper
“miR-124 is known to be expressed in the CNS by neuronal cells23,39–41.”
From MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway (2011) · cites this paper as [23]
In the citing paper
“Such expression in neurons of the adult brain is shared with mouse miR-124 [30].”
From MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system (2007) · cites this paper as [30]
In the citing paper
“This profile is one of the best conserved miRNA patterns, as a similar restriction to mature neurons is seen for mouse and fly miR-124 [12,30].”
From MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system (2007) · cites this paper as [30]
In the citing paper
“miR-23 is involved in neuronal specification, and miR-146a implicated in the prevention of neuroligin 1-dependent synaptogenesis, and both were enriched in astrocytes compared to neurons [54, 67].”
From Differential RNA packaging into small extracellular vesicles by neurons and astrocytes (2021) · cites this paper as [67]
In the citing paper
“being prominently observed in differentiating neuronal cells29,31”
From MiR-128-3p – a gray eminence of the human central nervous system (2024) · cites this paper as [31]
Citations
Cites
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948
The functions of animal microRNAs
Ambros, V. (2004) · Nature · doi:10.1038/nature02871 · Cited by 10,728
MicroRNAs: small RNAs with a big role in gene regulation
He, L., & Hannon, G. J. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1379 · Cited by 7,118
Prediction of Mammalian MicroRNA Targets
Lewis, B. P., Shih, I.-H., Jones-Rhoades, M. W., Bartel, D. P., & Burge, C. B. (2003) · Cell · doi:10.1016/s0092-8674(03)01018-3 · Cited by 5,199
Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M., Rai, K., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242606799 · Cited by 5,111
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
Reinhart, B. J., Slack, F. J., Basson, M., Pasquinelli, A. E., Bettinger, J. C., Rougvie, A. E., Horvitz, H. R., & Ruvkun, G. (2000) · Nature · doi:10.1038/35002607 · Cited by 4,989
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
Calin, G. A., Sevignani, C., Dumitru, C. D., Hyslop, T., Noch, E., Yendamuri, S., Shimizu, M., Rattan, S., Bullrich, F., Negrini, M., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0307323101 · Cited by 4,096
John, B., Enright, A. J., Aravin, A., Tuschl, T., Sander, C., & Marks, D. S. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020363 · Cited by 3,796
MicroRNA targets in Drosophila
Enright, A. J., John, B., Gaul, U., Tuschl, T., Sander, C., & Marks, D. S. (2003) · Genome Biology · doi:10.1186/gb-2003-5-1-r1 · Cited by 3,597
Cited by
Sorted by citations
Items 601–700 of 715
Epigenetics, Stem Cells, and Cellular Differentiation
Juliandi, B., Abematsu, M., & Nakashima, K. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-375709-8.00019-8 · Cited by 1
The Ticking of the Epigenetic Clock: Antipsychotic Drugs in Old Age
Sfera, A., Osorio, C. P., Inderias, L., & Cummings, M. A. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00122 · Cited by 1
Mesenchymal stem cells and exosomes in tissue regeneration and remodeling
Kiang, J. G. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-818561-2.00005-9 · Cited by 1
MicroRNA Biomarkers in Primary Brain Malignancies
Mustafov, D., Seriah, S., Malik, R., & Braoudaki, M. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.108386 · Cited by 1
microRNAs regulation and its role as biomarkers in diseases ⁎
Zhou, H., Ge, X., & Xue, X. (2016) · Oncology and Translational Medicine · doi:10.1007/s10330-015-0116-6 · Cited by 2
Doğan, A., Beker, M., Dallı, T., & Elibol, B. (2024) · Acta Medica Nicomedia · doi:10.53446/actamednicomedia.1562729 · Cited by 1
Medrano, G. (2018) · Cited by 1
Li, Y., Kong, D., Ahmad, A., Bao, B., & Sarkar, F. H. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405544-5.00005-8 · Cited by 1
Rna Interference: From basics to Therapeutics
Singh, S. K., & Hajeri, P. B. (2012) · doi:10.1002/9781119967309.ch6 · Cited by 1
Decoding Drug Abuse in Noncoding RNA?
Wu, D.-Y., & Satterlee, J. S. (2007) · The Scientific World JOURNAL · doi:10.1100/tsw.2007.260 · Cited by 1
Rybak‐Wolf, A. (2009) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-7441 · Cited by 1
Spinal cord injury: a systematic review and meta-analysis of microRNA alterationsPreprint
Tigchelaar, S., Wadhwa, H., Mathur, M. B., He, Z., & Tharin, S. A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.05.551159 · Cited by 1
Detera‐Wadleigh, S. D., & Yoshikawa, T. (2008) · Nucleic acids and molecular biology · doi:10.1007/978-3-540-85383-1_1
Gene Profiling of the Failing Heart: Epigenetics
Marı́n-Garcı́a, J. (2010) · Humana Press eBooks · doi:10.1007/978-1-60761-147-9_3
Differentiation of neural stem cells in fragile X syndrome
Tervonen, T. A. (2008) · Työväentutkimus Vuosikirja
Tarantino, C. (2010) · Università degli Studi di Napoli Federico II · doi:10.6092/unina/fedoa/4314
Ciafrè, S. A. (2007) · Cambridge University Press eBooks · doi:10.1017/cbo9780511541766.029
Analysis of Transcriptome Alterations in Parkinson’s Disease
Filatova, E. V., Shadrina, M. I., Slominsky, P. A., & Limborsk, S. (2011) · InTech eBooks · doi:10.5772/21070
Rational engineering of microRNA-regulated viruses for cancer gene therapy
Ylösmäki, E. O. (2013)
Arai, Y., Huttner, W. Β., & Calegari, F. (2010) · Springer eBooks · doi:10.1007/978-90-481-9075-1_13
Neurogênese e esquizofrenia: estudo molecular de associação
Purim, S. G. (2006) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.46.2006.tde-12022007-150206
Control of gene expression in prostate epithelial cell differentiation hierarchy
Rane, J. K. (2012) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
Noncoding RNAs in Neural Stem Cell Development
Bian, S., & Su, T. (2012) · InTech eBooks · doi:10.5772/29434
Mellios, N. (2009) · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · doi:10.13028/pz41-4991
Pluripotency and Early Cell Fate Decisions are Orchestrated by microRNAs
Jung, M., & Schroeder, I. S. (2013) · Wiley eBooks · doi:10.1002/9781118695999.ch16
UNDERSTANDING NANOG'S ROLE IN CANCER BIOLOGY
Badeaux, M. D. (2011) · Digital Commons-TMC (Texas Medical Center)
Expression analysis of Drosophila melanogaster microRNAs
Yalçın, A. (2007) · doi:10.53846/goediss-188
Expression profiling and functional studies of non-coding RNAs in the central nervous system
Dubinsky, A. N., Wilson, M. E., Russo, A. F., Bassuk, A. G., McCray, P. B., & Davidson, B. L. (2011) · doi:10.17077/etd.um0zdvm1
THE INDISPENSIBLE MISSION OF miRNA IN HUMAN DISORDERS
Khatri, P. S. (2013) · Journal of Drug Discovery and Therapeutics
Development of Methods for Retinal Ganglion Cell Replacement in Glaucoma
Jones, M. F. (2013) · UCL Discovery (University College London)
371. Optimization of Feline Immunodeficiency Viral Vectors for RNA Interference
Harper, S. Q., Staber, P. D., Rowley, C. R., Fineberg, S. K., Ochoa, D., Stein, C. S., & Davidson, B. L. (2006) · Molecular Therapy · doi:10.1016/j.ymthe.2006.08.430
MicroRNAs' role in brain development and disease
Fineberg, S. K., Davidson, B. L., Anderson, M. G., Russo, A. F., Cornell, R. A., & Johnson, W. A. (2010) · doi:10.17077/etd.qahvaifc
Sociaux, S. S. (2019)
Global gene profiling utilizing a cell model of spinal muscular atrophy
Miho, M. (2012) · Library, Museums and Press - UDSpace (University of Delaware)
Role of brain-enriched microRNAs during neural development
Fuchs, H. R. (2011) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-7806
Danner, D. J., Barnes, J., & Mersey, B. D. (2007) · Cambridge University Press eBooks · doi:10.1017/cbo9780511541766.012
miRNAs in TPA-induced differentiation of HL-60 cells
Kozu, T. (2007) · Cambridge University Press eBooks · doi:10.1017/cbo9780511541766.032
Characterisation of novel therapies to mitigate inflammation in retinal degenerations
Saxena, K. (2015) · ANU Open Research (Australian National University) · doi:10.25911/5d78d614a6941
MicroRNAs as Future Therapeutic Targets for Spinal Cord Injury
Awad, H., Malik, O. S., Brown, M., & Tili, E. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405544-5.00026-5 · Cited by 1
Gene Profiling, Energy Metabolism, and Remodeling of the Failing Heart
Marı́n-Garcı́a, J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-404599-6.00013-5
Regulation of Alternative Splicing by microRNAs
Gaur, R. K. (2009) · CRC Press eBooks · doi:10.1201/9781420008708.ch14
Vasques, L. R., Schoof, C. R. G., & Botelho, E. L. D. S. (2011) · CRC Press eBooks · doi:10.1201/b10882-9
Localization and Function Of RNA Interference in the Cerebral Cortex
Pena, J. (2025) · Digital Commons - RU (Rockefeller University) · doi:10.48496/5dx1-a532
Functional Analysis of Cortical Neuron Migration Using miRNA Silencing
Prévôt, P.-P., Volvert, M.-L., Deiters, A., & Nguyen, L. (2016) · Neuromethods · doi:10.1007/7657_2016_13
Effects of glyceollin on mRNA expression in the female mouse brain.
Bamji, S. F. (2016) · doi:10.18297/etd/2502
Abrahão, D. P. S. (2017) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2017.tde-27012017-115339
Investigating microRNA-target interactions during skeletal muscle development in chicken embryos
Viaut, C. (2017) · UEA Digital Repository (University of East Anglia)
Sibony, M. (2013) · TSpace (University of Toronto)
microRNAs in Oligodendrocyte Myelination and Repair in the Central Nervous System
Zhao, X., Wang, H., & Lu, Q. R. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804402-5.00011-x
MicroRNA expression profile of Danio rerio brain exposed to ethanol
Ferreira, V. (2010) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
MicroRNA functions and RNAi-mediated pathways
Appasani, K. (2007)
Yazdi, A. N., Sahraei, N., & Ahmadifar, M. (2020) · Modern Medical Laboratory Journal · doi:10.30699/mmlj17.3.1.35
Physiological and Pathological Functions of Mammalian MicroRNAs
Ma, X., Wang, L., Cao, Z., Hu, H., Lu, Z., Xu-Monette, Z. Y., Young, K. H., & Li, Y. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.95612-5
Conti, A., Merlo, L., La, D., & Aguennouz, M. (2011) · InTech eBooks · doi:10.5772/20172
Identification and characterization of novel microRNA regulators of myogenesis
Anthony, N. B. (2017) · doi:10.82308/41090
Williamson, V. S. (2012) · VCU Scholars Compass (Virginia Commonwealth University) · doi:10.25772/seyx-fq65
Arai, Y., Huttner, W. Β., & Calegari, F. (2013) · Springer eBooks · doi:10.1007/978-94-007-5690-8_12
Tarn, W. (2014) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.718278237.793497898
Ryder, S. P. (2009) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.1158729.618947
Biomarkers in Hypoxic Brain Injury: Methods, Discoveries, and Applications
Gutte, S. H., Azim, A., & Patnaik, R. (2022) · Biomarkers in disease · doi:10.1007/978-3-030-87302-8_26-1
Nezhad, A. F., & Dehghan, S. (2022) · Preprints.org · doi:10.20944/preprints202208.0263.v1
Biomarkers in Hypoxic Brain Injury: Methods, Discoveries, and Applications
Gutte, S. H., Azim, A., & Patnaik, R. (2023) · Biomarkers in disease · doi:10.1007/978-3-031-07395-3_26
Liu, S., Goldstein, R. H., Scepansky, E. M., & Rosenblatt, M. (2023) · doi:10.1158/0008-5472.22382354.v1
Liu, S., Goldstein, R. H., Scepansky, E. M., & Rosenblatt, M. (2023) · doi:10.1158/0008-5472.22382354
Wei, J. J., Wang, F., Kong, L., Xu, S., Doucette, T. A., Ferguson, S. D., Yang, Y., McEnery, K., Jethwa, K. R., Gjyshi, O., et al. (2023) · doi:10.1158/0008-5472.22394859
Wei, J. J., Wang, F., Kong, L., Xu, S., Doucette, T. A., Ferguson, S. D., Yang, Y., McEnery, K., Jethwa, K. R., Gjyshi, O., et al. (2023) · doi:10.1158/0008-5472.22394859.v1
Li, Y., Kong, D., Ahmad, A., Bao, B., & Sarkar, F. H. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-820719-2.00005-3
Relieving the epigenetic blockade in progressive ms
Tiane, A. (2023) · Research Publications (Maastricht University) · doi:10.26481/dis.20230606at
Mahnke, A. H., Rouzer, S. K., Tseng, A. M., Salem, N. A., & Miranda, R. C. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-21863-7.00015-9
Luo, X., Jean‐Toussaint, R., Saçan, A., & Ajit, S. K. (2021) · Figshare · doi:10.6084/m9.figshare.14954702
Luo, X., Jean‐Toussaint, R., Saçan, A., & Ajit, S. K. (2021) · Figshare · doi:10.6084/m9.figshare.14954705
Luo, X., Jean‐Toussaint, R., Saçan, A., & Ajit, S. K. (2021) · Figshare · doi:10.6084/m9.figshare.14954708
Luo, X., Jean‐Toussaint, R., Saçan, A., & Ajit, S. K. (2021) · Figshare · doi:10.6084/m9.figshare.14954699
Balaban, P. M., & Borodinova, A. A. (2024) · Журнал высшей нервной деятельности им И П Павлова · doi:10.31857/s0044467724060023
lncRNA NR_146969 promotes the progression of lung adenocarcinoma
Chen, Y., Wang, J., Gu, L., Chen, H., Gai, Z., Hu, R., Qing, B., Yuan, Y., & Xia, Z. (2025) · Experimental Cell Research · doi:10.1016/j.yexcr.2025.114535
Balaban, P. M., & Borodinova, A. A. (2025) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-025-01805-z
Role of microRNA in spinal cord injury and therapeutic perspectives
Xu, S. (2025) · New discovery. · doi:10.61958/offm7627
Cruz, L., Ferreira, F. M., Lopes‐Ramos, C. M., Wei, Z., Hendriks, W. T. J., Jinnah, H. A., Nakaya, H. I., Bragg, D. C., Krichevsky, A. M., Breakefield, X. O., et al. (2025) · The FASEB Journal · doi:10.1096/fj.202501157r · Cited by 1
RNAi in Malignant Brain Tumors: Relevance to Molecular and Translational Research
Nakada, M., Kita, D., Hayashi, Y., Kawakami, K., Hamada, J., & Minamoto, T. (2010) · RNA technologies · doi:10.1007/978-3-642-12168-5_5
Sacco, J., Starr, E., Weaver, A., Dietz, R., & Spocter, M. A. (2024) · Figshare · doi:10.6084/m9.figshare.26640424
Guidi, M., Muiños-Gimeno, M., Kagerbauer, B., Martı́, E., Estivill, X., & Espinosa‐Parrilla, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14438144
Guidi, M., Muiños-Gimeno, M., Kagerbauer, B., Martı́, E., Estivill, X., & Espinosa‐Parrilla, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14438162
Sacco, J., Starr, E., Weaver, A., Dietz, R., & Spocter, M. A. (2024) · Figshare · doi:10.6084/m9.figshare.26640427
Mannaert, A., Amemiya, C. T., & Bossuyt, F. (2021) · Figshare · doi:10.6084/m9.figshare.14434336
Guidi, M., Muiños-Gimeno, M., Kagerbauer, B., Martı́, E., Estivill, X., & Espinosa‐Parrilla, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14438156
Mannaert, A., Amemiya, C. T., & Bossuyt, F. (2021) · Figshare · doi:10.6084/m9.figshare.14434339
Guidi, M., Muiños-Gimeno, M., Kagerbauer, B., Martı́, E., Estivill, X., & Espinosa‐Parrilla, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14438159
Sacco, J., Starr, E., Weaver, A., Dietz, R., & Spocter, M. A. (2024) · Figshare · doi:10.6084/m9.figshare.26640421
Guidi, M., Muiños-Gimeno, M., Kagerbauer, B., Martı́, E., Estivill, X., & Espinosa‐Parrilla, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14438177
Guidi, M., Muiños-Gimeno, M., Kagerbauer, B., Martı́, E., Estivill, X., & Espinosa‐Parrilla, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14438168
Guidi, M., Muiños-Gimeno, M., Kagerbauer, B., Martı́, E., Estivill, X., & Espinosa‐Parrilla, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14438150
Mannaert, A., Amemiya, C. T., & Bossuyt, F. (2021) · Figshare · doi:10.6084/m9.figshare.14434333
Tigchelaar, S., He, Z., & Tharin, S. A. (2022) · Figshare · doi:10.6084/m9.figshare.19522514
Metadata
- Authors
- Smirnova, L., Gräfe, A., Seiler, A., Schumacher, S., Nitsch, R., & Wulczyn, F. G.
- Affiliations
- Charité – Universitätsmedizin Berlin (DE)
- German Federal Institute for Risk Assessment (BfR) (DE)
- Corresponding author
- Wulczyn, F. Gregory
- Venue
- European Journal of Neuroscience
- Publisher
- Wiley
- Published
- 2005-03
- Volume
- 21
- Issue
- 6
- Pages
- 1469-1477
- ISSN
- 0953-816X (ISSN-L)
- 1460-9568
- OpenAlex
- W2116641097
- Cited by
- 707
- References
- 55
- Citations by year
- 2026: 5 · 2025: 11 · 2024: 13 · 2023: 23 · 2022: 22 · 2021: 34 · 2020: 27 · 2019: 29 · 2018: 30 · 2017: 20 · 2016: 37 · 2015: 51 · 2014: 50 · 2013: 52 · 2012: 54
- FWCI
- 11.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- OpenAgrar (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- microRNA, brain development, miRNA expression regulation, astrocytes, embryonic neurons, miR-124, miR-128, miR-125, miR-23, miR-26, miR-29, miR-9, embryonic stem cell differentiation, temporal gene expression
- MeSH terms
- Animals, Animals, Newborn, Cell Differentiation, Cell Line, Neurons, Stem Cells, Gene Expression Regulation, Developmental, MicroRNAs, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
