The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Regulation of miRNA expression during neural cell specification
Abstract
MicroRNA (miRNA) are a newly recognized class of small, noncoding RNA molecules that participate in the developmental control of gene expression. We have studied the regulation of a set of highly expressed neural miRNA during mouse brain development. Temporal control is a characteristic of miRNA regulation in C. elegans and Drosophila, and is also prominent in the embryonic brain. We observed significant differences in the onset and magnitude of induction for individual miRNAs. Comparing expression in cultures of embryonic neurons and astrocytes we found marked lineage specificity for each of the miRNA in our study. Two of the most highly expressed miRNA in adult brain were preferentially expressed in neurons (mir-124, mir-128). In contrast, mir-23, a miRNA previously implicated in neural specification, was restricted to astrocytes. mir-26 and mir-29 were more strongly expressed in astrocytes than neurons, others were more evenly distributed (mir-9, mir-125). Lineage specificity was further explored using reporter constructs for two miRNA of particular interest (mir-125 and mir-128). miRNA-mediated suppression of both reporters was observed after transfection of the reporters into neurons but not astrocytes. miRNA were strongly induced during neural differentiation of embryonic stem cells, suggesting the validity of the stem cell model for studying miRNA regulation in neural development.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The decrease in miR-23 levels can lead to the accumulation of Hes1 during retinal acid-induced neural differentiation in NT2 cells, which in turn affects neural differentiation.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“miR-23 has the ability to affect neural differentiation.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“Hes1 is also directly targeted by miR-124, and the knockdown of miR-124 levels mediated by locked nucleic acids is similar to the effect of miR-23 inhibition.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“It indicates that the regulation of neural development by miR-23 is probably achieved through the combined action of other miRNAs.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“A basic helix-loop-helix transcriptional repressor, named Hes1, is an authentic target of miR-23.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“miR-23 is specifically expressed in astrocytes of the adult brain and is one of the miRNAs that are highly expressed in neurons during brain development.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“The expression level of Hes1 increases, ultimately hindering neuronal differentiation of P19 cells induced by the retinoic acid [[129], [130], [131]].”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“Notably, three miRNAs (miR-23, miR-26 and miR-29) that are found in oligodendrocyte lineage cells were previously described as enriched in astrocytes (Smirnova et al., 2005).”
From Identification of Dynamically Regulated MicroRNA and mRNA Networks in Developing Oligodendrocytes (2008) · cites this paper as Smirnova et al., 2005
In the citing paper
“miR-124 is known to be expressed in the CNS by neuronal cells23,39–41.”
From MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway (2011) · cites this paper as [23]
In the citing paper
“Such expression in neurons of the adult brain is shared with mouse miR-124 [30].”
From MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system (2007) · cites this paper as [30]
In the citing paper
“This profile is one of the best conserved miRNA patterns, as a similar restriction to mature neurons is seen for mouse and fly miR-124 [12,30].”
From MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system (2007) · cites this paper as [30]
In the citing paper
“miR-23 is involved in neuronal specification, and miR-146a implicated in the prevention of neuroligin 1-dependent synaptogenesis, and both were enriched in astrocytes compared to neurons [54, 67].”
From Differential RNA packaging into small extracellular vesicles by neurons and astrocytes (2021) · cites this paper as [67]
In the citing paper
“being prominently observed in differentiating neuronal cells29,31”
From MiR-128-3p – a gray eminence of the human central nervous system (2024) · cites this paper as [31]
Citations
Cites
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948
The functions of animal microRNAs
Ambros, V. (2004) · Nature · doi:10.1038/nature02871 · Cited by 10,728
MicroRNAs: small RNAs with a big role in gene regulation
He, L., & Hannon, G. J. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1379 · Cited by 7,118
Prediction of Mammalian MicroRNA Targets
Lewis, B. P., Shih, I.-H., Jones-Rhoades, M. W., Bartel, D. P., & Burge, C. B. (2003) · Cell · doi:10.1016/s0092-8674(03)01018-3 · Cited by 5,199
Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M., Rai, K., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242606799 · Cited by 5,111
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
Reinhart, B. J., Slack, F. J., Basson, M., Pasquinelli, A. E., Bettinger, J. C., Rougvie, A. E., Horvitz, H. R., & Ruvkun, G. (2000) · Nature · doi:10.1038/35002607 · Cited by 4,989
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
Calin, G. A., Sevignani, C., Dumitru, C. D., Hyslop, T., Noch, E., Yendamuri, S., Shimizu, M., Rattan, S., Bullrich, F., Negrini, M., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0307323101 · Cited by 4,096
John, B., Enright, A. J., Aravin, A., Tuschl, T., Sander, C., & Marks, D. S. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020363 · Cited by 3,796
MicroRNA targets in Drosophila
Enright, A. J., John, B., Gaul, U., Tuschl, T., Sander, C., & Marks, D. S. (2003) · Genome Biology · doi:10.1186/gb-2003-5-1-r1 · Cited by 3,597
Cited by
Sorted by citations
Items 501–600 of 715
miRNA-mediated immune regulation and immunotherapeutic potential in glioblastoma
Jethwa, K. R., Wei, J., McEnery, K., & Heimberger, A. B. (2011) · Clinical Investigation · doi:10.4155/cli.11.159 · Cited by 11
Long Noncoding RNAs: Emerging Players in Medulloblastoma
Laneve, P., Rea, J. N., & Caffarelli, E. (2019) · Frontiers in Pediatrics · doi:10.3389/fped.2019.00067 · Cited by 12
Naaman, H., Rall, G. F., Matullo, C. M., Veksler‐Lublinsky, I., Shemer‐Avni, Y., & Gopas, J. (2017) · PLoS ONE · doi:10.1371/journal.pone.0187077 · Cited by 11
The Role of Astrocytes in Tumor Growth and Progression
Gronseth, E. I., Wang, L., Harder, D. R., & Ramchandran, R. (2018) · InTech eBooks · doi:10.5772/intechopen.72720 · Cited by 12
Measles Virus Persistent Infection of Human Induced Pluripotent Stem Cells
Naaman, H., Rabinski, T., Yizhak, A., Mizrahi, S. S., Avni, Y. S., Taube, R., Rager‐Zisman, B., Weinstein, Y., Rall, G. F., Gopas, J., et al. (2018) · Cellular Reprogramming · doi:10.1089/cell.2017.0034 · Cited by 11
Correction: MicroRNA-Based Promotion of Human Neuronal Differentiation and Subtype Specification
Stappert, L., Borghese, L., Roese-Koerner, B., Weinhold, S., Koch, P., Terstegge, S., Uhrberg, M., Wernet, P., & stle, O. B. ⁄. (2013) · PLoS ONE · doi:10.1371/annotation/b03fbc42-8f70-4873-9cce-854e48249a13 · Cited by 11
Bioimaging of transcriptional activity of microRNA124a during neurogenesis
Ko, H. Y., Lee, J., Lee, Y. S., Choi, Y., Ali, B. A., Al-Khedhairy, A. A., & Kim, S. (2015) · Biotechnology Letters · doi:10.1007/s10529-015-1912-3 · Cited by 10
Physiological and Pathological Functions of Mammalian MicroRNAs
Liu, M., Jiang, S., Lu, Z., Li, Y., & Young, K. H. (2010) · Elsevier eBooks · doi:10.1016/b978-0-08-046884-6.00223-2 · Cited by 10
Shen, Y., Liao, D., Chen, J., Wang, Y.-C., Lai, I., Liou, Y., Chen, Y.-J., Luu, S.-U., & Chen, C. (2009) · Schizophrenia Research · doi:10.1016/j.schres.2009.08.003 · Cited by 10
Chen, J., Li, W., Li, Y., He, S., Li, L., Liang, L., Song, Y., Qin, D., & Zheng, H. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.05.031 · Cited by 10
Soy glyceollins regulate transcript abundance in the female mouse brain
Bamji, S. F., Page, R. B., Patel, D., Sanders, A., Alvarez, A. R., Gambrell, C., Naik, K., Raghavan, A. M., Burow, M. E., Boué, S. M., et al. (2015) · Functional & Integrative Genomics · doi:10.1007/s10142-015-0442-3 · Cited by 10
Overview of the role and action mechanism of microRNA-128 in viral infections
Alshahrani, S. H., Alameri, A. A., Kahar, F., Ramírez‐Coronel, A. A., Obaid, R. F., Alsaikhan, F., Zabibah, R. S., Qasim, Q. A., Altalbawy, F. M. A., Mustafa, Y. F., et al. (2023) · Microbial Pathogenesis · doi:10.1016/j.micpath.2023.106020 · Cited by 10
Identification of differentially expressed micro-RNA in rotator cuff tendinopathy
Hall, K. E., Sarkissian, E. J., Sharpe, O., Robinson, W. H., & Abrams, G. D. (2019) · Muscles Ligaments and Tendons Journal · doi:10.32098/mltj.01.2018.02 · Cited by 9
Role of mammalian long non-coding RNAs in normal and neuro oncological disorders
Singh, N. (2021) · Genomics · doi:10.1016/j.ygeno.2021.07.015 · Cited by 9
Pinapati, K. K., Tandon, R., Tripathi, P., & Srivastava, N. (2022) · Reviews in Medical Virology · doi:10.1002/rmv.2383 · Cited by 9
Margiana, R., Kzar, H. H., Hussam, F., Hameed, N. M., Al‐qaim, Z. H., Al-Gazally, M. E., Kandee, M., Saleh, M. M., Toshbekov, B. B. U., Tursunbaev, F., et al. (2023) · Pathology - Research and Practice · doi:10.1016/j.prp.2023.154705 · Cited by 9
MicroRNA and Diseases of the Nervous System
Omahen, D. A. (2011) · Neurosurgery · doi:10.1227/neu.0b013e318215a3b3 · Cited by 9
miRNAs and their putative roles in the development and progression of Parkinson's disease
Wong, G., & Nass, R. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2012.00315 · Cited by 9
Progress of reprogramming astrocytes into neuron
Liu, S., Xu, X., Omari‐Siaw, E., Yu, J., & Deng, W. (2024) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2024.103947 · Cited by 7
Aydın, E. P., Alsaadoni, H., Beğenen, A. G., Özer, Ö. A., Karamustafalioglu, K. O., & Pençe, S. (2022) · Psychiatry and Clinical Psychopharmacology · doi:10.5152/pcp.2022.22391 · Cited by 6
Screening for characteristic microRNAs between pre-invasive and invasive stages of cervical cancer
Zhu, X., WEN, S.-Y., Ai, Z., WANG, J., Xu, Y., & Teng, Y. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.3363 · Cited by 8
Substance P and Neprilysin in Chronic Pancreatitis
Mascetta, G., di Mola, F. F., Tavano, F., Selvaggi, F., Giese, N., Bassi, C., Büchler, M. W., Frieß, H., & Sebastiano, P. D. (2012) · European Surgical Research · doi:10.1159/000337869 · Cited by 8
Optical Imaging for Stem Cell Differentiation to Neuronal Lineage
Hwang, D. W., & Lee, D. S. (2012) · Nuclear Medicine and Molecular Imaging · doi:10.1007/s13139-011-0122-8 · Cited by 8
Could Mirna Expression Changes Be a Reliable Clinical Biomarker for Parkinson's disease?
Khoo, S. K., Neuman, L. A., Forsgren, L., Petillo, D., & Brundin, P. (2013) · Neurodegenerative Disease Management · doi:10.2217/nmt.13.53 · Cited by 9
KSRP silencing favors neural differentiation of P19 teratocarcinoma cells
Giovarelli, M., Bucci, G., Pasero, M., Gherzi, R., & Briata, P. (2013) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2013.02.008 · Cited by 8
The Emerging Impact of microRNAs in Neurotrauma Pathophysiology and Therapy
Bhalala, O. G. (2015) · Europe PMC (PubMed Central) · Cited by 8
MiRNA influences in mesenchymal stem cell commitment to neuroblast lineage development
Zammit, V., Brincat, M., Cassar, V., Baron, Y. M., Ayers, D., & Baron, B. (2018) · Non-coding RNA Research · doi:10.1016/j.ncrna.2018.11.002 · Cited by 8
Sun, J., Ye, L., Wang, C., Li, N., Wang, D., & Li, X. (2018) · PubMed Central · Cited by 8
Genetic Mechanisms of Cognitive Development
Mustafin, R. N., Kazantseva, A. V., Malykh, S. B., & Хуснутдинова, Э. К. (2020) · Russian Journal of Genetics · doi:10.1134/s102279542007011x · Cited by 9
The dynamic transcriptomic response of the goldfish brain under chronic hypoxia
Cortés-Ramírez, S. A., Farhat, E., Talarico, G. G. M., & Mennigen, J. A. (2024) · Comparative Biochemistry and Physiology Part D Genomics and Proteomics · doi:10.1016/j.cbd.2024.101233 · Cited by 7
Wu, R., Wang, N., Li, M., Zang, W., & Xu, Y. (2013) · Cell Biology International · doi:10.1002/cbin.10103 · Cited by 7
Regulation of a TrkB Alternative Transcript by microRNAs
Wong, J. (2014) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000365917 · Cited by 6
Burrows, K., Figueroa‐Hall, L. K., Alarbi, A. M., Stewart, J. L., Kuplicki, R., Tan, C., Hannafon, B. N., Ramesh, R., Savitz, J. B., Khalsa, S. S., et al. (2022) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2022.100582 · Cited by 7
Li, X., Chen, Y., Chi, Q., Hu, X., Xu, X., Zhang, Z., Qiu, M. S., & Zheng, K. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.11.012 · Cited by 7
Lee, Y., Boschian, C., & Ko, K. (2025) · RNA Biology · doi:10.1080/15476286.2025.2558631 · Cited by 7
Bassett, C. H., Triplett, H., Lott, K., Howard, K. M., & Kingsley, K. (2023) · Biomedicines · doi:10.3390/biomedicines11113003 · Cited by 6
Expression Profile of MiR-128 in the Astrocytoma Patients and Cell Lines
Xu, J., Liu, Y., Guo, S., Ma, S., Xiao, L., Wei, N., & Xue, R. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9401-1 · Cited by 6
Dorweiler, J. E., Ni, T., Zhu, J., Munroe, S. H., & Anderson, J. T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0099430 · Cited by 6
Sacco, J., Starr, E., Weaver, A., Dietz, R., & Spocter, M. A. (2023) · Canine Medicine and Genetics · doi:10.1186/s40575-023-00133-0 · Cited by 6
Epigenetic Regulation of Neural Differentiation from Embryonic Stem Cells
Shimomura, A., & Hashino, E. (2013) · InTech eBooks · doi:10.5772/53650 · Cited by 6
Mokabber, H., Vatankhah, M. A., & Najafzadeh, N. (2022) · Process Biochemistry · doi:10.1016/j.procbio.2022.01.016 · Cited by 7
Tigchelaar, S., He, Z., & Tharin, S. A. (2022) · Systematic Reviews · doi:10.1186/s13643-022-01921-8 · Cited by 6
Specific microRNAs modulate ES cell-derived neurogenesis
Krichevsky, A. M., Sonntag, K., Ole Isacson, A., & Kosik, K. S. (2005) · Cited by 6
Recent advances of miR-23 in human diseases and growth development
Qian, X., Jiang, Y., Yang, Y., Zhang, Y., Xu, N., Xu, B., Pei, K., Yu, Z., & Wu, W. (2025) · Non-coding RNA Research · doi:10.1016/j.ncrna.2024.12.010 · Cited by 5
Wang, R., Chen, L., Zhang, Y., Sun, B., & Liang, M. (2024) · Life · doi:10.3390/life14091125 · Cited by 5
Stem Cell-Derived Exosomal MicroRNAs as Novel Potential Approach for Multiple Sclerosis Treatment
Tahmasebi, F., Asl, E. R., Vahidinia, Z., & Barati, S. (2024) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-024-01478-1 · Cited by 6
Paradigms in miRNA biogenesis pathways
Panda, M., & Prajapati, V. K. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99661-7.00003-5 · Cited by 5
MicroRNAs e seu papel no desenvolvimento embrionário
Campos, V. F., Urtiaga, G., Gonçalves, B., Deschamps, J. C., & Collares, T. V. (2011) · Ciência Rural · doi:10.1590/s0103-84782011000100014 · Cited by 5
Regulation of Gene Expression in Neural Stem Cell Differentiation and Self-Renewal
Hashemzadeh, M. R., Seyedi, Z., Edalatmanesh, M. A., & Rafiei, S. (2015) · The Neuroscience Journal of Shefaye Khatam · doi:10.18869/acadpub.shefa.3.4.87 · Cited by 5
Heydari, M., Hojati, Z., & Dehbashi, M. (2021) · PubMed Central · doi:10.22074/cellj.2021.7047 · Cited by 5
Yamada, R., Okumura, S., Kono, Y., MIYAZAKI, A., Niwa, Y., Ito, T., Ueda, S., Ishiguro, T., Yoshinaga, M., Fujiwara, W., et al. (2021) · PubMed Central · doi:10.20407/fmj.2020-010 · Cited by 5
Guibinga, G.-H. (2015) · Advances in genetics · doi:10.1016/bs.adgen.2015.06.001 · Cited by 5
Corraliza-Gómez, M., Ianni, M., Nogueira, D. E. S., Salvador, W. O. S., Migueis, M., Garcı́a-Alloza, M., Rodrigues, C. A. V., Cabral, J. M. S., & Brites, D. M. T. O. (2026) · Journal of Biological Engineering · doi:10.1186/s13036-025-00597-7 · Cited by 4
The Emerging Role of microRNAs in Adult Stem Cells
Shookhoff, J. M., & Gallicano, G. I. (2011) · Humana Press eBooks · doi:10.1007/978-1-61779-002-7_3 · Cited by 4
Function Of Mir-125B In Zebrafish Neurogenesis
Le, M. T. N., Teh, C., Shyh‐Chang, N., Korzh, V. P., Lodish, H. F., & Lim, B. (2010) · Zenodo (CERN European Organization for Nuclear Research) · doi:10.5281/zenodo.1073123 · Cited by 4
Schreiber, S., Daum, P., Danzer, H., Hauke, M., Jäck, H., & Wittmann, J. (2023) · Biomolecules · doi:10.3390/biom13101517 · Cited by 4
Andrade‐da‐Costa, B. L. D. S., Isaac, A. R., Augusto, R. L., de Souza, R. F., Freitas, H. R., & Reis, R. A. D. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815238-6.00029-8 · Cited by 4
Mannaert, A., Amemiya, C. T., & Bossuyt, F. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-658 · Cited by 4
Prevention of Lymphocyte Neurotoxic Effects by microRNA Delivery
Pulliero, A., Marengo, B., Fenoglio, D., Parodi, A., Cereda, C., Domenicotti, C., Orcesi, S., Galli, J., Olivieri, I., Filaci, G., et al. (2014) · MicroRNA · doi:10.2174/22115366113029990010 · Cited by 4
Comparative Functions of miRNAs in Embryonic Neurogenesis and Neuronal Network Formation
Ristori, E., & Nicoli, S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804402-5.00015-7 · Cited by 4
Zhao, Y., Zhou, H., Ayisi, C. L., Wang, Y., Wang, J., Chen, X., & Zhao, J. (2018) · Biology Open · doi:10.1242/bio.029082 · Cited by 4
Comparative Analysis of mi RNA ‐mediated Gene Regulation in Mammals
Zhang, Y., & Lv, Q. (2009) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0021754 · Cited by 4
New Players in the Neuroendocrine System
Wang, Y., Mead, E. A., Thekkumthala, A. P., & Pietrzykowski, A. Z. (2016) · Wiley eBooks · doi:10.1002/9781118760369.ch4 · Cited by 4
Argonaute identity defines the length of mature mammalian micrornas
Juvvuna, P. K. (2013) · doi:10.32657/10356/51099 · Cited by 4
MicroRNA and Alzheimer’s disease: Diagnostic biomarkers and potential therapeutic targets
Huang, Y., Chen, Y., He, Z., Lu, W., Lai, H., Wang, Y., & Wang, J. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-25-00002 · Cited by 4
Modulation of ZnT-1 by Let7a unveils a therapeutic potential in amyotrophic lateral sclerosis
Anzilotti, S., Franco, C., Valsecchi, V., Cuomo, O., Lombardi, G., Muraglia, N. D., Iesu, N. D., Laudati, G., Annunziato, L., Canzoniero, L. M. T., et al. (2025) · Neurotherapeutics · doi:10.1016/j.neurot.2025.e00571 · Cited by 4
Mseis-Jackson, N., Jiang, M. H., Sharma, M., Ranchod, A., Williams, C., Chen, X., & Li, H. (2025) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2025.102704 · Cited by 3
Ching, A.-S., & Ahmad‐Annuar, A. (2015) · Sains Malaysiana · doi:10.17576/jsm-2015-4410-14 · Cited by 3
Benson, D. L. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.0743-19.2019 · Cited by 3
MicroRNA-based targeting of the Rho/ROCK pathway in therapeutic strategies after spinal cord injury
Kimura, T., & Horikoshi, Y. (2022) · Neural Regeneration Research · doi:10.4103/1673-5374.346480 · Cited by 3
Zheng, H., Wang, X., Chen, S., Shi, X., Xie, J., Mao, W., Tian, J., & Wang, F. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00614 · Cited by 3
The Wide Variety of miRNA Expression Profiles in the Developing and Mature CNS
Kapsimali, M. (2009) · Research and perspectives in neurosciences · doi:10.1007/978-3-642-04298-0_2 · Cited by 3
Bioimaging of microRNA124a‐independent neuronal differentiation of human G2 neural stem cells
Lee, J., Hwang, D. W., Kim, S. U., Lee, D. N., Lee, Y. S., Heo, H., Ali, B. A., Al-Khedhairy, A. A., & Kim, S. (2015) · FEBS Open Bio · doi:10.1016/j.fob.2015.08.003 · Cited by 3
MicroRNA in Breast Cancer — Gene Regulators and Targets for Novel Therapies
Luqmani, Y. A., & Khajah, M. A. (2015) · InTech eBooks · doi:10.5772/59428 · Cited by 3
Conservation and Evolution of microRNAs in Animals
LIANG, Y., Zhang, S., Luo, Y., & Zhang, Q. (2012) · Scientia Sinica Vitae · doi:10.1360/052011-594 · Cited by 3
Molecular Beacon-Based MicroRNA Imaging During Neurogenesis
Lee, J., & Kim, S. (2015) · Methods in molecular biology · doi:10.1007/978-1-4939-3148-4_11 · Cited by 3
miRNA as a Marker for In Vitro Neurotoxicity Testing and Related Neurological Disorders
Smirnova, L., & Maertens, A. (2019) · Neuromethods · doi:10.1007/978-1-4939-9228-7_14 · Cited by 3
Self-citationZhang, R., Liu, Z., Hou, X., Wang, M., Xiong, Y., Lu, H., Wang, Y., Su, J., Liu, Y., Zhang, G., et al. (2020) · Acta Virologica · doi:10.4149/av_2020_304 · Cited by 3
miRNAs Targeting and Targeting miRNAs
Wang, Z. (2009) · Springer eBooks · doi:10.1007/978-3-642-00489-6_1 · Cited by 3
MicroRNAs in the Central Nervous System and Potential Roles of RNA Interference in Brain Tumors
Purow, B. W. (2009) · Humana Press eBooks · doi:10.1007/978-1-60327-553-8_27 · Cited by 3
Saumet, A., Vetter, G., Cougot, N., Bouttier, M., Rage, F., Arar, K., & Lecellier, C. (2008) · Springer eBooks · doi:10.1007/978-1-4020-8533-8_22 · Cited by 4
Mapping of Nervous System Diseases via MicroRNAs
(2016) · CRC Press eBooks · doi:10.1201/b19229 · Cited by 3
Chen, Y., Guo, L., Zan, G., Xu, C., Yao, S.-Y., Wu, S., Jiang, X., Liu, Z., Long, J.-D., Liu, B., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03441-y · Cited by 2
Yang, J., Xing, N., Xing, N., & Dong, L. (2022) · Tropical Journal of Pharmaceutical Research · doi:10.4314/tjpr.v21i4.12 · Cited by 2
Fiselier, A., Byeon, B., Ilnytskyy, Y., Kovalchuk, O., & Kovalchuk, I. (2022) · Epigenomes · doi:10.3390/epigenomes6040035 · Cited by 2
Smith, C. M., Catchpoole, D. R., & Hutvágner, G. (2024) · Scientific Reports · doi:10.1038/s41598-024-58870-6 · Cited by 2
Lentiviral Vectors in Huntington’s Disease Research and Therapy
Delzor, A., Dufour, N., & Déglon, N. (2013) · Neuromethods · doi:10.1007/978-1-62703-610-8_11 · Cited by 2
MicroRNA Regulation of Neuronal Differentiation and Plasticity
Barbato, C., & Ruberti, F. (2011) · Springer eBooks · doi:10.1007/978-3-642-22517-8_7 · Cited by 2
Epigenetic Control of Neural Stem Cell Self-Renewal and Specification
Sun, G., Zhao, C., & Shi, Y. (2008) · Springer eBooks · doi:10.1007/978-1-4020-8502-4_4 · Cited by 2
MicroRNA Profiling in CNS Tissue Using Microarrays
Saba, R., & Booth, S. A. (2008) · Springer eBooks · doi:10.1007/978-1-4020-8533-8_5 · Cited by 2
microRNAs in Ischemic Brain: The Fine-Tuning Specialists and Novel Therapeutic Targets
Dharap, A. A., Nakka, V. P., & Vemuganti, R. (2012) · Springer eBooks · doi:10.1007/978-1-4419-9530-8_17 · Cited by 2
Tseng, A. M., Mahnke, A. H., Salem, N. A., & Miranda, R. C. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812215-0.00030-3 · Cited by 2
Noncoding RNAs, Neurodevelopment, and Neurodegeneration
Chen, M., Deng, J., Yang, M., Zhu, K. Y., Liu, J., Zhu, L., & Wu, J. Y. (2013) · Wiley eBooks · doi:10.1002/9783527665433.ch9 · Cited by 2
MiR-208a reduces inflammatory responses in heart failure rats through β-catenin pathway
Song, Y., Guo, Y., Qin, J., Jia, X., & Yang, C. (2023) · Tropical Journal of Pharmaceutical Research · doi:10.4314/tjpr.v22i8.6 · Cited by 1
MicroRNA, a small non-coding RNA, how do you know?
Teati, A. A. (2023) · New discovery. · doi:10.61958/ndfc6362 · Cited by 1
Moshtaghioon, S., Elahi, M. M., Soltani, Z. E., Ahmadi, E., & Nabian, M. H. (2025) · Gene · doi:10.1016/j.gene.2025.149311 · Cited by 1
The role of non-coding RNA-mediated autophagy in Alzheimer’s disease
Wang, Y., Bao, G., Li, H., Li, X., & Lv, L. (2026) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2026.111860 · Cited by 1
A Computational Approach to Identifying miRNAs Implicated in Drosophila Neurodevelopment
Nenov, M., Nikolov, S., & Genova, G. (2012) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 1
MicroRNAs in Development, Stem Cell Differentiation, and Regenerative Medicine
Chang, B., Lemischka, I. R., & Schaniel, C. (2011) · Springer eBooks · doi:10.1007/978-3-642-22517-8_17 · Cited by 1
Progress on miRNA in mammal breast milk
Song, X., Jiang, J., & JIANG, Y.-Q. (2012) · Hereditas (Beijing) · doi:10.3724/sp.j.1005.2012.01233 · Cited by 1
Metadata
- Authors
- Smirnova, L., Gräfe, A., Seiler, A., Schumacher, S., Nitsch, R., & Wulczyn, F. G.
- Affiliations
- Charité – Universitätsmedizin Berlin (DE)
- German Federal Institute for Risk Assessment (BfR) (DE)
- Corresponding author
- Wulczyn, F. Gregory
- Venue
- European Journal of Neuroscience
- Publisher
- Wiley
- Published
- 2005-03
- Volume
- 21
- Issue
- 6
- Pages
- 1469-1477
- ISSN
- 0953-816X (ISSN-L)
- 1460-9568
- OpenAlex
- W2116641097
- Cited by
- 707
- References
- 55
- Citations by year
- 2026: 5 · 2025: 11 · 2024: 13 · 2023: 23 · 2022: 22 · 2021: 34 · 2020: 27 · 2019: 29 · 2018: 30 · 2017: 20 · 2016: 37 · 2015: 51 · 2014: 50 · 2013: 52 · 2012: 54
- FWCI
- 11.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- OpenAgrar (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- microRNA, brain development, miRNA expression regulation, astrocytes, embryonic neurons, miR-124, miR-128, miR-125, miR-23, miR-26, miR-29, miR-9, embryonic stem cell differentiation, temporal gene expression
- MeSH terms
- Animals, Animals, Newborn, Cell Differentiation, Cell Line, Neurons, Stem Cells, Gene Expression Regulation, Developmental, MicroRNAs, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
