The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Regulation of miRNA expression during neural cell specification
Abstract
MicroRNA (miRNA) are a newly recognized class of small, noncoding RNA molecules that participate in the developmental control of gene expression. We have studied the regulation of a set of highly expressed neural miRNA during mouse brain development. Temporal control is a characteristic of miRNA regulation in C. elegans and Drosophila, and is also prominent in the embryonic brain. We observed significant differences in the onset and magnitude of induction for individual miRNAs. Comparing expression in cultures of embryonic neurons and astrocytes we found marked lineage specificity for each of the miRNA in our study. Two of the most highly expressed miRNA in adult brain were preferentially expressed in neurons (mir-124, mir-128). In contrast, mir-23, a miRNA previously implicated in neural specification, was restricted to astrocytes. mir-26 and mir-29 were more strongly expressed in astrocytes than neurons, others were more evenly distributed (mir-9, mir-125). Lineage specificity was further explored using reporter constructs for two miRNA of particular interest (mir-125 and mir-128). miRNA-mediated suppression of both reporters was observed after transfection of the reporters into neurons but not astrocytes. miRNA were strongly induced during neural differentiation of embryonic stem cells, suggesting the validity of the stem cell model for studying miRNA regulation in neural development.
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In the citing paper
“The decrease in miR-23 levels can lead to the accumulation of Hes1 during retinal acid-induced neural differentiation in NT2 cells, which in turn affects neural differentiation.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“miR-23 has the ability to affect neural differentiation.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“Hes1 is also directly targeted by miR-124, and the knockdown of miR-124 levels mediated by locked nucleic acids is similar to the effect of miR-23 inhibition.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“It indicates that the regulation of neural development by miR-23 is probably achieved through the combined action of other miRNAs.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“A basic helix-loop-helix transcriptional repressor, named Hes1, is an authentic target of miR-23.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“miR-23 is specifically expressed in astrocytes of the adult brain and is one of the miRNAs that are highly expressed in neurons during brain development.”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“The expression level of Hes1 increases, ultimately hindering neuronal differentiation of P19 cells induced by the retinoic acid [[129], [130], [131]].”
From Recent advances of miR-23 in human diseases and growth development (2025) · cites this paper as [129]
In the citing paper
“Notably, three miRNAs (miR-23, miR-26 and miR-29) that are found in oligodendrocyte lineage cells were previously described as enriched in astrocytes (Smirnova et al., 2005).”
From Identification of Dynamically Regulated MicroRNA and mRNA Networks in Developing Oligodendrocytes (2008) · cites this paper as Smirnova et al., 2005
In the citing paper
“miR-124 is known to be expressed in the CNS by neuronal cells23,39–41.”
From MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway (2011) · cites this paper as [23]
In the citing paper
“Such expression in neurons of the adult brain is shared with mouse miR-124 [30].”
From MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system (2007) · cites this paper as [30]
In the citing paper
“This profile is one of the best conserved miRNA patterns, as a similar restriction to mature neurons is seen for mouse and fly miR-124 [12,30].”
From MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system (2007) · cites this paper as [30]
In the citing paper
“miR-23 is involved in neuronal specification, and miR-146a implicated in the prevention of neuroligin 1-dependent synaptogenesis, and both were enriched in astrocytes compared to neurons [54, 67].”
From Differential RNA packaging into small extracellular vesicles by neurons and astrocytes (2021) · cites this paper as [67]
In the citing paper
“being prominently observed in differentiating neuronal cells29,31”
From MiR-128-3p – a gray eminence of the human central nervous system (2024) · cites this paper as [31]
Citations
Cites
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948
The functions of animal microRNAs
Ambros, V. (2004) · Nature · doi:10.1038/nature02871 · Cited by 10,728
MicroRNAs: small RNAs with a big role in gene regulation
He, L., & Hannon, G. J. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1379 · Cited by 7,118
Prediction of Mammalian MicroRNA Targets
Lewis, B. P., Shih, I.-H., Jones-Rhoades, M. W., Bartel, D. P., & Burge, C. B. (2003) · Cell · doi:10.1016/s0092-8674(03)01018-3 · Cited by 5,199
Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M., Rai, K., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242606799 · Cited by 5,111
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
Reinhart, B. J., Slack, F. J., Basson, M., Pasquinelli, A. E., Bettinger, J. C., Rougvie, A. E., Horvitz, H. R., & Ruvkun, G. (2000) · Nature · doi:10.1038/35002607 · Cited by 4,989
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
Calin, G. A., Sevignani, C., Dumitru, C. D., Hyslop, T., Noch, E., Yendamuri, S., Shimizu, M., Rattan, S., Bullrich, F., Negrini, M., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0307323101 · Cited by 4,096
John, B., Enright, A. J., Aravin, A., Tuschl, T., Sander, C., & Marks, D. S. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020363 · Cited by 3,796
MicroRNA targets in Drosophila
Enright, A. J., John, B., Gaul, U., Tuschl, T., Sander, C., & Marks, D. S. (2003) · Genome Biology · doi:10.1186/gb-2003-5-1-r1 · Cited by 3,597
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Items 301–400 of 715
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Fineberg, S. K., Datta, P., Stein, C. S., & Davidson, B. L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038562 · Cited by 49
MicroRNA Signatures in Neurological Disorders
Shafi, G., Aliya, N., & Munshi, A. (2010) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100009902 · Cited by 50
Thinking about RNA? MicroRNAs in the brain
Barbato, C., Giorgi, C., Catalanotto, C., & Cogoni, C. (2008) · Mammalian Genome · doi:10.1007/s00335-008-9129-6 · Cited by 50
Small non-coding RNA signature in multiple sclerosis patients after treatment with interferon-β
Felice, B. D., Mondola, P., Sasso, A., Orefice, G., Morra, V. B., Vacca, G., Biffali, E., Borra, M., & Pannone, R. (2014) · BMC Medical Genomics · doi:10.1186/1755-8794-7-26 · Cited by 49
Chronological Changes in MicroRNA Expression in the Developing Human Brain
Moreau, M., Bruse, S., Jörnsten, R. J., Liu, Y., & Brzustowicz, L. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060480 · Cited by 48
Role of miRNAs and epigenetics in neural stem cell fate determination
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Liu, Y., Zhang, Y., Liu, P., Bai, H., Li, X., Xiao, J., Yuan, Q., Geng, S., Yin, H., Zhang, H., et al. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.11.004 · Cited by 45
RetractedFonseca, Á. Y. G., Martín-Jiménez, C., Barreto, G. E., Aristizábal-Pachón, A. F., & González, J. (2021) · Biomolecules · doi:10.3390/biom11081132 · Cited by 48
The microRNA pathway and fragile X mental retardation protein
LI, Y., Lin, L., & Jin, P. (2008) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2008.07.003 · Cited by 49
Pan, W., Wei, N., Xu, W., Wang, G., Gong, F., & Li, N. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.105835 · Cited by 47
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Lawson, S. K., Dobrikova, E. Y., Shveygert, M., & Gromeier, M. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.00695-12 · Cited by 47
Role of Connexins 30, 36, and 43 in Brain Tumors, Neurodegenerative Diseases, and Neuroprotection
Sánchez, O. F., Rodríguez, A. V., Velasco-España, J. M., Murillo, L. C., Sutachan, J. J., & Albarracin, S.-L. (2020) · Cells · doi:10.3390/cells9040846 · Cited by 46
Epigenetic alchemy for cell fate conversion
Kondo, T. (2006) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2006.07.001 · Cited by 46
Silvestro, S., & Mazzon, E. (2022) · Cells · doi:10.3390/cells11142177 · Cited by 46
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Hong, J., Zhang, H., Kawase‐Koga, Y., & Sun, T. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00151 · Cited by 44
Jones, T. A., Jeyapalan, J. N., Forshew, T., Tatevossian, R., Lawson, A. R. J., Patel, S. N., Doctor, G. T., Mumin, M., Picker, S. R., Phipps, K. P., et al. (2015) · Acta Neuropathologica Communications · doi:10.1186/s40478-015-0266-3 · Cited by 44
Epigenetic regulation of neural stem cell property from embryo to adult
Murao, N., Noguchi, H., & Nakashima, K. (2016) · Neuroepigenetics · doi:10.1016/j.nepig.2016.01.001 · Cited by 47
Dai, Y., Zhang, W. R., Wang, Y. M., Liu, X. F., Li, X., Ding, X. B., & Guo, H. (2016) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-016-2656-7 · Cited by 44
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Spaull, R., McPherson, B., Gialeli, A., Clayton, A., Uney, J. B., Heep, A., & Llana, O. C. (2019) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2019.01.004 · Cited by 42
Segaran, R. C., Chan, L. Y., Wang, H., Sethi, G., & Tang, F. R. (2020) · Current Medicinal Chemistry · doi:10.2174/0929867327666200121122910 · Cited by 42
Shi, L., Wan, Y., Sun, G., Gu, X., Qian, C., Yan, W., Zhang, S., Pan, T., Wang, Z., & You, Y. (2012) · NeuroMolecular Medicine · doi:10.1007/s12017-012-8188-8 · Cited by 42
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Dogini, D. B., Ribeiro, P. A. O., Rocha, C. S., Pereira, T. C., & Lopes‐Cendes, Í. (2008) · Journal of Molecular Neuroscience · doi:10.1007/s12031-008-9068-4 · Cited by 42
Uziel, O., Beery, E., Dronichev, V., Samocha, K., Gryaznov, S. M., Weiss, L., Slavin, S., Kushnir, M., Nordenberg, Y., Rabinowitz, C., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009132 · Cited by 40
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Nelson, P. T., & Wilfred, B. R. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.04.044 · Cited by 42
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Farrell, B. C., Power, E. M., & Dermott, K. M. (2010) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2010.10.001 · Cited by 37
Ylla, G., Piulachs, M., & Bellés, X. (2017) · BMC Genomics · doi:10.1186/s12864-017-4177-5 · Cited by 38
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Pavlou, M. A. S., Grandbarbe, L., Buckley, N. J., Niclou, S. P., & Michelucci, A. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.12.007 · Cited by 37
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Nielsen, M. M., & Pedersen, J. S. (2021) · Scientific Reports · doi:10.1038/s41598-021-88480-5 · Cited by 38
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Thum, T., Galuppo, P., KNEITZ, S., WOLF, C., VANLAAKE, L., ENGELHARDT, S., Ertl, G., & BAUERSACHS, J. (2007) · European Journal of Heart Failure Supplements · doi:10.1016/s1567-4215(07)60006-x · Cited by 38
Fine-tuning the brain: MicroRNAs
Vreugdenhil, E., & Berezikov, E. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.08.001 · Cited by 36
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Che, M., Gong, W., Zhao, Y., & Liu, M. (2020) · Molecular Medicine · doi:10.1186/s10020-020-00219-6 · Cited by 37
Li, X., Peng, Z., Long, L., Lu, X., Zhu, K., Tuo, Y., Chen, N., Zhao, X., Wang, L., & Wan, Y. (2020) · Experimental & Molecular Medicine · doi:10.1038/s12276-020-00536-0 · Cited by 37
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Ouyang, Y., Xu, L., Liu, S., & Giffard, R. G. (2014) · Advances in neurobiology · doi:10.1007/978-3-319-08894-5_9 · Cited by 38
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Greene, S. B., Herschkowitz, J. I., & Rosen, J. M. (2010) · Current Drug Targets · doi:10.2174/138945010792006762 · Cited by 39
Sin, O., & Nollen, E. A. A. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-1985-0 · Cited by 43
Yao, W., Guo, G., Zhang, Q., Fan, L., Wu, N., & Bo, Y. (2014) · Virology · doi:10.1016/j.virol.2014.04.007 · Cited by 36
Mao, G., Ren, P., Wang, G., Yan, F., & Zhang, Y. (2016) · Journal of Molecular Neuroscience · doi:10.1007/s12031-016-0871-z · Cited by 37
Motohashi, N., Alexander, M. S., Casar, J. C., & Kunkel, L. M. (2012) · Stem Cells and Development · doi:10.1089/scd.2011.0721 · Cited by 35
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Suster, I., & Feng, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22136765 · Cited by 39
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Barbato, C., Ciotti, M. T., Serafino, A., Calissano, P., & Cogoni, C. (2007) · Brain Research · doi:10.1016/j.brainres.2007.07.088 · Cited by 36
Ko, H. Y., Lee, D. S., & Kim, S. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.07185.x · Cited by 34
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Manakov, S. A., Grant, S. G., & Enright, A. J. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-419 · Cited by 34
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Gioia, U., Carlo, V. D., Caramanica, P., Toselli, C., Cinquino, A., Marchioni, M., Laneve, P., Biagioni, S., Bozzoni, I., Cacci, E., et al. (2014) · RNA Biology · doi:10.4161/rna.35508 · Cited by 33
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Buechner, J., Henriksen, J. R., Haug, B. H., Tømte, E., Flægstad, T., & Einvik, C. (2010) · Differentiation · doi:10.1016/j.diff.2010.09.184 · Cited by 33
Lattanzi, A., Gentner, B., Corno, D., Tomaso, T. D., Mestdagh, P., Speleman, F., Naldini, L., & Gritti, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067411 · Cited by 32
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Li, J., Fang, L., Yu, W., & Wang, Y. (2015) · Oncology Letters · doi:10.3892/ol.2015.2973 · Cited by 33
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Sun, Y. K., Guo, F., Bagnoli, M., Xue, F.-X., Sun, B., Shmulevich, I., Mezzanzanica, D., Chen, K., Sood, A. K., Yang, D., et al. (2015) · 癌症：英文版 · doi:10.5732/cjc.014.10284 · Cited by 30
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Obora, K., Onodera, Y., Takehara, T., Frampton, J. P., Hasei, J., Ozaki, T., Teramura, T., & Fukuda, K. (2017) · Scientific Reports · doi:10.1038/srep43604 · Cited by 30
Zheng, Y., Pan, C., Chen, M., Pei, A., Xie, L., & Zhu, S. (2019) · Oncology Reports · doi:10.3892/or.2019.6961 · Cited by 30
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Li, F., & Zhou, M. (2019) · Acta Neurologica Belgica · doi:10.1007/s13760-019-01076-9 · Cited by 30
Smith, S. M. C., Kimyon, R. S., & Watters, J. J. (2014) · ASN NEURO · doi:10.1042/an20130050 · Cited by 30
Stary, C. M., Sun, X., Ouyang, Y., Li, L., & Giffard, R. G. (2016) · Mitochondrion · doi:10.1016/j.mito.2016.08.013 · Cited by 29
Smirnova, L., Block, K., Sittka, A., Oelgeschläger, M., Seiler, A. E. M., & Luch, A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098892 · Cited by 31
Self-citationYin, H., Shen, L., Xu, C., & Liu, J. (2018) · Neurochemical Research · doi:10.1007/s11064-018-2625-5 · Cited by 29
Geoffroy, A., Cherif, L. S., Pourié, G., Helle, D., Umoret, R., Guéant, J., Bossenmeyer‐Pourié, C., & Daval, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20040973 · Cited by 29
Jeon, E. S., Shin, J. H., Hwang, S. J., Moon, G. J., Bang, O. Y., & Kim, H. H. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.01.114 · Cited by 28
Sibley, C. R., & Wood, M. J. A. (2011) · Journal of Molecular Medicine · doi:10.1007/s00109-011-0781-z · Cited by 28
Functional Studies of microRNAs in Neural Stem Cells: Problems and Perspectives
Åkerblom, M., Sachdeva, R., & Jakobsson, J. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00014 · Cited by 30
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Gizak, A., Duda, P., Pielka, E., McCubrey, J. A., & Rakus, D. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2020.118696 · Cited by 29
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Karam, R., & Wilkinson, M. (2012) · RNA Biology · doi:10.4161/rna.9.1.18010 · Cited by 28
Nassar, A., Satarker, S., Gurram, P. C., Upadhya, D., Fayaz, S., & Nampoothiri, M. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03437-1 · Cited by 27
Mao, S., Li, H., Sun, Q., Zen, K., Zhang, C., & Li, L. (2013) · FEBS Journal · doi:10.1111/febs.12680 · Cited by 27
Maisel, M., Habisch, H., Royer, L. A., Herr, A., Milošević, J., Hermann, A., Liebau, S., Brenner, R. E., Schwarz, J., Schroeder, M., et al. (2010) · Experimental Cell Research · doi:10.1016/j.yexcr.2010.06.012 · Cited by 26
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Kim, S., Hwang, D. W., & Lee, D. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.06935.x · Cited by 27
Li, L., & Stary, C. M. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/6032306 · Cited by 27
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Metadata
- Authors
- Smirnova, L., Gräfe, A., Seiler, A., Schumacher, S., Nitsch, R., & Wulczyn, F. G.
- Affiliations
- Charité – Universitätsmedizin Berlin (DE)
- German Federal Institute for Risk Assessment (BfR) (DE)
- Corresponding author
- Wulczyn, F. Gregory
- Venue
- European Journal of Neuroscience
- Publisher
- Wiley
- Published
- 2005-03
- Volume
- 21
- Issue
- 6
- Pages
- 1469-1477
- ISSN
- 0953-816X (ISSN-L)
- 1460-9568
- OpenAlex
- W2116641097
- Cited by
- 707
- References
- 55
- Citations by year
- 2026: 5 · 2025: 11 · 2024: 13 · 2023: 23 · 2022: 22 · 2021: 34 · 2020: 27 · 2019: 29 · 2018: 30 · 2017: 20 · 2016: 37 · 2015: 51 · 2014: 50 · 2013: 52 · 2012: 54
- FWCI
- 11.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- OpenAgrar (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- microRNA, brain development, miRNA expression regulation, astrocytes, embryonic neurons, miR-124, miR-128, miR-125, miR-23, miR-26, miR-29, miR-9, embryonic stem cell differentiation, temporal gene expression
- MeSH terms
- Animals, Animals, Newborn, Cell Differentiation, Cell Line, Neurons, Stem Cells, Gene Expression Regulation, Developmental, MicroRNAs, Mice
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