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Autism: Towards an Integration of Clinical, Genetic, Neuropsychological, and Neurobiological Perspectives

Bailey, Anthony, Phillips, Wendy, Rutter, Michael·1996·Journal of Child Psychology and Psychiatry

Abstract

Autism consitutes one of the best validated child psychiatric disorders. Empirical research has succeeded in delineating the key clinical phenomena, in demonstrating strong genetic influences on the underlying liability, and in identifying basic cognitive deficits. A range of neurobiological abnormalities has also been found, although the replicability of specific findings has not been high. An understanding of the causal processes leading to autism, and accounting for the marked variability in its manifestations, requires an integration across these different levels of enquiry. Although this is not yet possible, a partial integration provides a useful strategy for identifying key research questions, the limitations of existing hypotheses, and future research directions that are likely to prove fruitful. The research findings for each research level are critically reviewed in order to consider how to move towards an integration across levels.

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Metadata

Authors
Bailey, A., Phillips, W., & Rutter, M.
Venue
Journal of Child Psychology and Psychiatry
Publisher
Wiley
Published
1996-01
Volume
37
Issue
1
Pages
89-126
ISSN
  • 0021-9630 (ISSN-L)
  • 1469-7610
OpenAlex
W2074973198
Cited by
769
References
39
FWCI
23.32
Type
journal article
Language
en
Open access
closed

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Bailey, A., Phillips, W., & Rutter, M. (1996). Autism: Towards an Integration of Clinical, Genetic, Neuropsychological, and Neurobiological Perspectives. Journal of Child Psychology and Psychiatry. https://doi.org/10.1111/j.1469-7610.1996.tb01381.x

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