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The prevalence of dementia: A quantitative integration of the literature
Abstract
ABSTRACT— Data from studies of dementia prevalence between 1945 to 1985 were analyzed statistically. Prevalence rates were found to vary as a function of methodological differences between studies. However, despite these differences, the relationship between prevalence and age was found to be consistent across studies, with rates doubling every 5.1 years. Across studies, Alzheimer's disease (AD) was found to be more common in women, with a tendency for multi‐infarct dementia (MID) to be more common in men. There were also national differences in the relative prevalence of AD and MID, with MID being more commmon in Japanese and Russian studies, no difference in Finnish and American studies, and an excess of AD in other Western European countries.
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Plassman, B. L., Langa, K. M., Fisher, G. G., Heeringa, S. G., Weir, D. R., Ofstedal, M. B., Burke, J. R., Hurd, M. D., Potter, G. G., Rodgers, W. L., et al. (2007) · Neuroepidemiology · doi:10.1159/000109998 · Cited by 1,932
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
Lewis, J., Dickson, D. W., Lin, W.-L., Chisholm, L., Corral, A., Jones, G., Yen, S.-H., Sahara, N., Skipper, L., Yager, D., et al. (2001) · Science · doi:10.1126/science.1058189 · Cited by 1,611
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The incidence of dementia: A meta-analysis
Jorm, A. F., & Jolley, D. (1998) · Neurology · doi:10.1212/wnl.51.3.728 · Cited by 903
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Andersen, K., Launer, L. J., Dewey, M. E., Letenneur, L., Ott, A., Copeland, J. R. M., Dartigues, J.-F., Kragh–Sorensen, P., Baldereschi, M., Brayne, C., et al. (1999) · Neurology · doi:10.1212/wnl.53.9.1992 · Cited by 650
Fratiglioni, L., Viitanen, M., von Strauss, E., Tontodonati, V., Herlitz, A., & Winblad, B. (1997) · Neurology · doi:10.1212/wnl.48.1.132 · Cited by 556
Sex differences in cognitive impairment and Alzheimer’s disease
Li, R., & Singh, M. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.01.002 · Cited by 527
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Erkinjuntti, T., Østbye, T., Steenhuis, R., & Hachinski, V. (1997) · New England Journal of Medicine · doi:10.1056/nejm199712043372306 · Cited by 450
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White, L. (1996) · JAMA · doi:10.1001/jama.1996.03540120033030 · Cited by 437
Mukadam, N., Sommerlad, A., Huntley, J., & Livingston, G. (2019) · The Lancet Global Health · doi:10.1016/s2214-109x(19)30074-9 · Cited by 416
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Letenneur, L., Gilleron, V, Commenges, D., Helmer, C., Orgogozo, J. M., & Dartigues, J. F. (1999) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.66.2.177 · Cited by 406
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Guure, C. B., Ibrahim, N. A., Adam, M. B., & Said, S. M. (2017) · BioMed Research International · doi:10.1155/2017/9016924 · Cited by 298
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De Leon, M., George, A., Stylopoulos, L., Smith, G., & Miller, D. (1989) · The Lancet · doi:10.1016/s0140-6736(89)90911-2 · Cited by 284
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Carroll, J. C., Rosario, E. R., Kreimer, S., Villamagna, A., Gentzschein, E., Stanczyk, F. Z., & Pike, C. J. (2010) · Brain Research · doi:10.1016/j.brainres.2010.10.009 · Cited by 273
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Honjo, K., Black, S. E., & Verhoeff, N. P. L. G. (2012) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100015547 · Cited by 152
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Zhang, Z.-X., Zahner, G. E. P., Román, G. C., Liu, X.-H., Wu, C.-B., Hong, Z., Hong, X., Tang, M.-N., Zhou, B., Qu, Q.-M., et al. (2006) · Neuroepidemiology · doi:10.1159/000096131 · Cited by 119
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Lin, R.-T., Lai, C.-L., Tai, C.-T., Liu, C.-K., Yen, Y.-Y., & Howng, S.-L. (1998) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(98)00225-1 · Cited by 119
Mathieu-Kia, A.-M., Fan, L.-Q., Kreek, M. J., Simon, E. J., & Hiller, J. M. (2001) · Brain Research · doi:10.1016/s0006-8993(00)03302-3 · Cited by 118
Ho, S. C., Woo, J., Sham, A., Chan, S. G., & Yu, A. L. (2001) · International Journal of Epidemiology · doi:10.1093/ije/30.6.1389 · Cited by 100
Carpenter, W. T., Bustillo, J. R., Thaker, G. K., van Os, J., Krueger, R. F., & Green, M. J. (2009) · Psychological Medicine · doi:10.1017/s0033291709990286 · Cited by 99
Beattie, A. M., Daker-White, G., Gilliard, J., & Means, R. (2002) · Aging & Mental Health · doi:10.1080/13607860220142396 · Cited by 99
Adelman, S., Blanchard, M., Rait, G., Leavey, G., & Livingston, G. (2011) · British Journal of Psychiatry · doi:10.1192/bjp.bp.110.086405 · Cited by 87
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Vardarajan, B. N., Faber, K. M., Bird, T. D., Bennett, D. A., Rosenberg, R., Boeve, B. F., Graff-Radford, N. R., Goate, A. M., Farlow, M., Sweet, R. A., et al. (2014) · JAMA Neurology · doi:10.1001/jamaneurol.2013.5570 · Cited by 73
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Bennett, H. P., Corbett, A. J., Gaden, S., Grayson, D. A., Kril, J. J., & Broe, G. A. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50608.x · Cited by 73
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Streiner, D. L., Patten, S. B., Anthony, J. C., & Cairney, J. (2009) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.296 · Cited by 69
Acupuncture for vascular dementia
Peng, W., Wang, Y., Zhang, Y., & Liang, C. M. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004987.pub2 · Cited by 67
Exley, C., House, E., Polwart, A., & Esiri, M. M. (2012) · Journal of Alzheimer's Disease · doi:10.3233/jad-2012-120766 · Cited by 59
Objective and Subjective Cognitive Problems among Caregivers and Matched Non-caregivers
Vitaliano, P. P., Ustundag, O., & Borson, S. (2017) · The Gerontologist · doi:10.1093/geront/gnv690 · Cited by 55
Alcohol consumption and cognitive impairment in older men: A mendelian randomization study
Almeida, O. P., Hankey, G. J., Yeap, B. B., Golledge, J., & Flicker, L. (2014) · Neurology · doi:10.1212/wnl.0000000000000255 · Cited by 46
Alzheimer's disease: cerebral glaucoma?
Wostyn, P., Audenaert, K., & De Deyn, P. P. (2010) · Medical Hypotheses · doi:10.1016/j.mehy.2009.12.019 · Cited by 51
Sachdev, P., Andrews, G., Hobbs, M. J., Sunderland, M., & Anderson, T. M. (2009) · Psychological Medicine · doi:10.1017/s0033291709990262 · Cited by 48
Li, L., Cao, D., Desmond, R., Rahman, A., Lah, J. J., Levey, A. I., & Zamrini, E. (2008) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000164271 · Cited by 45
Alsaqati, M., Thomas, R. S., & Kidd, E. J. (2018) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glx135 · Cited by 43
Bali, V., Chatterjee, S., Carnahan, R. M., Chen, H., Johnson, M. L., & Aparasu, R. R. (2015) · Psychiatric Services · doi:10.1176/appi.ps.201500011 · Cited by 23
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Corrada, M. M., Brookmeyer, R., Berlau, D., Paganini-Hill, A., & Kawas, C. H. (2008) · Neurology · doi:10.1212/01.wnl.0000310773.65918.cd · Cited by 11
Rose’Meyer, R. B., Mellick, A. S., Garnham, B. G., Harrison, G. J., Massa, H. M., & Griffiths, L. R. (2003) · Brain Research Protocols · doi:10.1016/s1385-299x(02)00219-2 · Cited by 4
Metadata
- Authors
- Jorm, A. F., Korten, A. E., & Henderson, A. S.
- Venue
- Acta Psychiatrica Scandinavica
- Publisher
- Wiley
- Published
- 1987-11
- Volume
- 76
- Issue
- 5
- Pages
- 465-479
- ISSN
- 0001-690X (ISSN-L)
- 1600-0447
- OpenAlex
- W2057182436
- Cited by
- 1,296
- References
- 0
- FWCI
- 12.63
- Type
- journal article
- Language
- en
- Open access
- closed
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