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Cited by 36Dementia and Cognitive Impairment ResearchAging and Gerontology ResearchAging, Health, and Disability

Prevalence of dementia after age 90: Results from The 90+ Study

Corrada, M. M., Brookmeyer, R., Berlau, D., Paganini-Hill, A., Kawas, C. H.·2008·Neurology
DOI 10.1212/01.wnl.0000310773.65918.cd
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Abstract

Background: Although the prevalence of dementia increases with age from ages 65 to 85, whether this increase continues after age 90 is unclear. Most studies reporting on dementia prevalence do not have sufficient participants to estimate prevalence for specific ages and sexes above age 90. Here, we estimate age- and sex-specific prevalence of all-cause dementia in the oldest-old, those aged 90 and older. Methods: Participants are 911 elderly from The 90+ Study, a population-based study of aging and dementia in people aged 90 and above. Dementia was diagnosed using in-person examinations as well as telephone and informant questionnaires. Results: The overall prevalence of all-cause dementia was higher in women (45%, 95% CI = 41.5–49.0) than men (28%, 95% CI = 21.7–34.2). Among women, prevalence increased with age after age 90, essentially doubling every 5 years. A lower prevalence of dementia was significantly associated with higher education in women but not in men. Conclusions: In a very large sample of participants aged 90 and older, prevalence of all-cause dementia doubled every 5 years for women but not men.

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  • Based on studies that show clinical AD, MCI, and preclinical AD are common in the elderly, by the new scheme the vast majority of those past the age of 85 have AD.

    “Based on studies that show clinical AD [6, 8], MCI [88], and preclinical AD [67] are common in the elderly, by this scheme that vast majority of those past the age of 85 have AD (Figure 2).”

    From Brain aging, Alzheimer's disease, and mitochondria (2011) · cites this paper as [8]

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Authors
Corrada, M. M., Brookmeyer, R., Berlau, D., Paganini-Hill, A., & Kawas, C. H.
Affiliations
  • University of Southern California (US)
  • From the Department of Neurology (M.M.C., C.H.K.), Department of Neurobiology & Behavior (C.H.K.), and Institute for Brain Aging and Dementia (M.M.C., D.B., C.H.K.), University of California Irvine; Department of Biostatistics (R.B.), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; and Department of Preventive Medicine (A.P.-H.), Keck School of Medicine, University of Southern California, CA.
ORCID
Venue
Neurology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2008-07-29
Volume
71
Issue
5
Pages
337-343
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
DOI
10.1212/01.wnl.0000310773.65918.cd
OpenAlex
W73956888
Cited by
11
References
32
Citations by year
2018: 1 · 2015: 1 · 2014: 4 · 2013: 1 · 2012: 2
FWCI
0.46
Type
journal article
Language
en
Open access
closed
Locations
Neurology (publishedVersion)
Funders
National Institute on Aging (R01AG021055)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Aging and Gerontology Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
Keywords
dementia prevalence, oldest old, sex differences, age-specific prevalence, all-cause dementia

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