The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The incidence of dementia: A meta-analysis
Abstract
Objective To carry out a meta-analysis of the age-specific incidence of all dementias, including AD and vascular dementia. Background Several meta-analyses have been carried out on dementia prevalence, but none on its incidence. Methods We used loess-curve fitting to analyze data from 23 published studies reporting age-specific incidence data. Results The incidence of both dementia and AD rose exponentially up to the age of 90 years, with no sign of leveling off. The incidence rates for vascular dementia varied greatly from study to study, but the trend was also for an exponential rise with age. There was no sex difference in dementia incidence (p = 0.21), but women tended to have a higher incidence of AD in very old age, and men tended to have a higher incidence of vascular dementia at younger ages. East Asian countries had a lower incidence of dementia than Europe (p = 0.0004), and also tended to have a lower incidence of AD. Conclusions The incidence of dementia rises exponentially to the age of 90 years. Any sex differences are small, and incidence is lower in East Asia than in Europe.
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Depression is a major risk factor for cognitive decline and dementia.
“Depression is a major risk factor for cognitive decline and dementia.”
From Risk of Dementia Among Elderly Nursing Home Patients Using Paroxetine and Other Selective Serotonin Reuptake Inhibitors (2015) · cites this paper as [9]
A meta-analysis by Jorm and Jolley found that depression was consistently associated with an increased risk of dementia in both case-control studies (95% CI for RR=1.16-3.50) and prospective studies (CI for RR=1.08-3.20).
“A meta-analysis by Jorm and Jolley (9) found that depression was consistently associated with an increased risk of dementia in both case-control studies (95% confidence interval [CI] for relative risk [RR] =1.16-3.50) and prospective studies (CI for RR=1.08-3.20).”
From Risk of Dementia Among Elderly Nursing Home Patients Using Paroxetine and Other Selective Serotonin Reuptake Inhibitors (2015) · cites this paper as [9]
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Metadata
- Authors
- Jorm, A. F., & Jolley, D.
- Affiliations
- Australian National University (AU)
- ORCID
- Jorm, A. F.
- Venue
- Neurology
- Published
- 1998-09
- Volume
- 51
- Issue
- 3
- Pages
- 728-733
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2168516263
- Cited by
- 903
- References
- 2
- Citations by year
- 2026: 16 · 2025: 27 · 2024: 30 · 2023: 14 · 2022: 28 · 2021: 27 · 2020: 35 · 2019: 41 · 2018: 35 · 2017: 42 · 2016: 33 · 2015: 37 · 2014: 29 · 2013: 42 · 2012: 38
- FWCI
- 4.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
- Keywords
- dementia incidence, age-specific incidence, Alzheimer's disease, vascular dementia, sex differences, oldest old
- MeSH terms
- Age Factors, Aged, Aged, 80 and over, Alzheimer Disease, Analysis of Variance, Asia, Dementia, Europe, Female, Humans, Male, Middle Aged, Sex Factors, United States, Dementia, Vascular
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