Systematic methodological review: developing a framework for a qualitative semi‐structured interview guide
Open accessAbstract
Aim: To produce a framework for the development of a qualitative semi‐structured interview guide. Background: Rigorous data collection procedures fundamentally influence the results of studies. The semi‐structured interview is a common data collection method, but methodological research on the development of a semi‐structured interview guide is sparse. Design: Systematic methodological review. Data sources: We searched PubMed, CINAHL , Scopus and Web of Science for methodological papers on semi‐structured interview guides from October 2004–September 2014. Having examined 2,703 titles and abstracts and 21 full texts, we finally selected 10 papers. Review methods: We analysed the data using the qualitative content analysis method. Results: Our analysis resulted in new synthesized knowledge on the development of a semi‐structured interview guide, including five phases: (1) identifying the prerequisites for using semi‐structured interviews; (2) retrieving and using previous knowledge; (3) formulating the preliminary semi‐structured interview guide; (4) pilot testing the guide; and (5) presenting the complete semi‐structured interview guide. Conclusion: Rigorous development of a qualitative semi‐structured interview guide contributes to the objectivity and trustworthiness of studies and makes the results more plausible. Researchers should consider using this five‐step process to develop a semi‐structured interview guide and justify the decisions made during it.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Internal testing of the interview questions was done within the research team to remove ambiguities from the questions.
“Internal testing of the interview questions was done within the research team to remove ambiguities from the questions (Kallio et al. 2016).”
From S-LCA of lithium mining in Chile and its potential impacts on water and the local community (2025) · cites this paper as Kallio et al. 2016
The topic guide was drafted following the framework from Kallio et al., reviewed with the second author, and piloted with a research collaborator before starting the interviews.
“Following the framework from Kallio et al.67, the first author (SS) drafted a topic guide, inspired by existing qualitative research in this area, reviewed with the second author (AC), and piloted with a research collaborator before starting the interviews”
From “It happened to be the perfect thing”: experiences of generative AI chatbots for mental health (2024) · cites this paper as [67]
Semi-structured interviews are a well-established approach to enable participants to express diverse perceptions and focus on topics most meaningful to them, particularly for complex or emotionally sensitive topics.
“We collected data using semi-structured interviews, as a well-established approach to enable participants to express diverse perceptions and focus on topics most meaningful to them, in particular for complex or emotionally sensitive topics that they may not be used to discussing with others67.”
From “It happened to be the perfect thing”: experiences of generative AI chatbots for mental health (2024) · cites this paper as [67]
The interview guide was developed based on a review of relevant literature and expert consultations to ensure it effectively addressed the study's aims.
“The guide was developed based on a review of relevant literature and expert consultations to ensure it effectively addressed the study’s aims [18].”
From Leading with AI in critical care nursing: challenges, opportunities, and the human factor (2024) · cites this paper as [18]
Cites
Lincoln, Y. S., Guba, E. G., & Pilotta, J. J. (1985) · International Journal of Intercultural Relations · doi:10.1016/0147-1767(85)90062-8 · Cited by 45,787 · see citing works
The qualitative content analysis process
Elo, S., & Kyngäs, H. (2008) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2007.04569.x · Cited by 22,617 · see citing works
Strategies for ensuring trustworthiness in qualitative research projects
Shenton, A. K. (2004) · Education for Information · doi:10.3233/efi-2004-22201 · Cited by 9,748 · see citing works
The qualitative research interview
DiCicco‐Bloom, B., & Crabtree, B. F. (2006) · Medical Education · doi:10.1111/j.1365-2929.2006.02418.x · Cited by 4,995 · see citing works
Qualitative Psychology: A Practical Guide to Research Methods
Brooks, S. (2008) · QMiP Bulletin · doi:10.53841/bpsqmip.2008.1.6.47 · Cited by 4,360 · see citing works
Qualitative research in health care: Assessing quality in qualitative research
Mays, N. (2000) · BMJ · doi:10.1136/bmj.320.7226.50 · Cited by 3,742 · see citing works
The SAGE encyclopedia of qualitative research methods
Brodsky, A. (2011) · Choice Reviews Online · doi:10.5860/choice.46-4214 · Cited by 3,347 · see citing works
Quality and trustworthiness in qualitative research in counseling psychology.
Morrow, S. L. (2005) · Journal of Counseling Psychology · doi:10.1037/0022-0167.52.2.250 · Cited by 3,199 · see citing works
Methods of data collection in qualitative research: interviews and focus groups
Gill, P., Stewart, K., Treasure, E. T., & Chadwick, B. L. (2008) · BDJ · doi:10.1038/bdj.2008.192 · Cited by 2,779 · see citing works
Qualitative Research Design: An Interactive Approach
Pitman, M. A. (1998) · Anthropology & Education Quarterly · doi:10.1525/aeq.1998.29.4.499 · Cited by 2,404 · see citing works
Qualitative Research in Nursing and Healthcare
Holloway, I., & Wheeler, S. (2016) · Cited by 2,228 · see citing works
Kvale, S. (2007) · doi:10.4135/9781849208963 · Cited by 2,182 · see citing works
Essentials of Nursing Research: Appraising Evidence for Nursing Practice
Stannard, D. (2012) · AORN Journal · doi:10.1016/j.aorn.2011.10.009 · Cited by 2,083 · see citing works
Qualitative Research Interviewing
Wengraf, T. (2001) · SAGE Publications Ltd eBooks · doi:10.4135/9781849209717 · Cited by 2,025 · see citing works
Qualitative Interviewing (2nd ed.): The Art of Hearing Data
Rubin, H., & Rubin, I. S. (2005) · Sage eBooks · doi:10.4135/9781452226651 · Cited by 1,953 · see citing works
Qualitative Interview Design: A Practical Guide for Novice Investigators
Turner, D. (2014) · The Qualitative Report · doi:10.46743/2160-3715/2010.1178 · Cited by 1,704 · see citing works
Qualitative Research Interviewing: Biographic Narrative and Semi-Structured Methods
Wengraf, T. (2001) · Medical Entomology and Zoology · Cited by 1,506 · see citing works
Collecting data using a semi‐structured interview: a discussion paper
Barriball, K. L., & While, A. (1994) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.1994.tb01088.x · Cited by 1,466 · see citing works
The SAGE Encyclopedia of Social Science Research Methods
Lewis‐Beck, M. S., Bryman, A. E., & Liao, T. F. (2004) · Sage eBooks · doi:10.4135/9781412950589 · Cited by 1,449 · see citing works
Mastering the semi-structured interview and beyond: from research design to analysis and publication
(2014) · Choice Reviews Online · doi:10.5860/choice.51-2430 · Cited by 860 · see citing works
Quality in qualitative research
Kitto, S. C., Chesters, J., & Grbich, C. (2008) · Medical Journal of Australia · doi:10.5694/j.1326-5377.2008.tb01595.x · Cited by 728 · see citing works
Semi-structured interviews: guidance for novice researchers
Whiting, L. S. (2008) · Nursing Standard · doi:10.7748/ns2008.02.22.23.35.c6420 · Cited by 514 · see citing works
Chenail, R. J. (2016) · The Qualitative Report · doi:10.46743/2160-3715/2009.2821 · Cited by 451 · see citing works
Qualitative Interviewing Techniques and Styles
Kelly, S. (2010) · SAGE Publications Ltd eBooks · doi:10.4135/9781446268247.n17 · Cited by 410 · see citing works
A reflection on the use of semi-structured interviews
Dearnley, C. A. (2005) · Nurse Researcher · doi:10.7748/nr2005.07.13.1.19.c5997 · Cited by 393 · see citing works
Qualitative Research in Health Care
Webster, J. A. (2005) · Nursing Older People · doi:10.7748/nop.16.10.43.s21 · Cited by 335 · see citing works
How I Learned to Design and Conduct Semi-structured Interviews: An Ongoing and Continuous Journey
Rabionet, S. E. (2014) · The Qualitative Report · doi:10.46743/2160-3715/2011.1070 · Cited by 329 · see citing works
How I Learned to Design and Conduct Semi-structured Interviews: An Ongoing and Continuous Journey
Rabionet, S. E. (2016) · The Qualitative Report · doi:10.46743/2160-3715/2009.2850 · Cited by 230 · see citing works
Chenail, R. J. (2014) · The Qualitative Report · doi:10.46743/2160-3715/2011.1051 · Cited by 214 · see citing works
Cridland, E. K., Jones, S. C., Caputi, P., & Magee, C. A. (2015) · Journal of Intellectual and Developmental Disability · doi:10.3109/13668250.2014.964191 · Cited by 151 · cited 10× · see citing works
“1994), ‘topics’ (Barriball & While 1994, Cridland et al. 2015) and just ‘questions’ (Dearnley 2005, Whiting 2008, Chenail 2011, Rabionet 2011, Cridland et al. 2015;).”
BackgroundMethodInfluentialSemi‐Structured Interviewing in Practice‐Close Research
Baumbusch, J. (2010) · Journal for Specialists in Pediatric Nursing · doi:10.1111/j.1744-6155.2010.00243.x · Cited by 145 · see citing works
How to investigate the use of medicines by consumers
Hardon, A. P., Hodgkin, C., & Fresle, D. (2004) · Cited by 135 · see citing works
What have sampling and data collection got to do with good qualitative research?
Gibbs, L., Kealy, M., Willis, K., Green, J., Welch, N., & Daly, J. (2007) · Australian and New Zealand Journal of Public Health · doi:10.1111/j.1753-6405.2007.00140.x · Cited by 133 · see citing works
Campbell, M., Egan, M., Lorenc, T., Bond, L., Popham, F., Fenton, C., & Benzeval, M. (2014) · Systematic Reviews · doi:10.1186/2046-4053-3-114 · Cited by 103 · see citing works
Krauss, S. E., Hamzah, A., Omar, Z. B., et al. (2014) · The Qualitative Report · doi:10.46743/2160-3715/2009.1382 · Cited by 71 · see citing works
Assessing the quality of qualitative research
Salmon, P. (2012) · Patient Education and Counseling · doi:10.1016/j.pec.2012.11.018 · Cited by 62 · see citing works
Åstedt-Kurki, P. M., & Heikkinen, R. (1994) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.1994.tb02375.x · Cited by 62 · see citing works
Qualitative research: quality results?
Cleary, M. L., Horsfall, J. M., & Hayter, M. (2014) · Journal of Advanced Nursing · doi:10.1111/jan.12172 · Cited by 21 · see citing works
Rethinking quality in qualitative research
Bell, E. (2014) · Australian Journal of Rural Health · doi:10.1111/ajr.12119 · Cited by 7 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Series: Practical guidance to qualitative research. Part 3: Sampling, data collection and analysis
Moser, A., & Korstjens, I. (2018) · European Journal of General Practice · doi:10.1080/13814788.2017.1375091 · Cited by 2,509 · see citing works
Semistructured interviewing in primary care research: A balance of relationship and rigour
DeJonckheere, M., & Vaughn, L. M. (2019) · Family Medicine and Community Health · doi:10.1136/fmch-2018-000057 · Cited by 1,898 · see citing works
Nelson, C. A., Pérez-Chada, L. M., Creadore, A., Li, S. J., Lo, K., Manjaly, P., Pournamdari, A. B., Tkachenko, E., Barbieri, J. S., Ko, J. M., et al. (2020) · JAMA Dermatology · doi:10.1001/jamadermatol.2019.5014 · Cited by 278 · see citing works
Dahri, N. A., Yahaya, N., Al-Rahmi, W. M., Aldraiweesh, A., Alturki, U., Almutairy, S., Shutaleva, A., & Soomro, R. B. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e29317 · Cited by 239 · see citing works
“This method facilitated direct communication with ChatGPT participants, providing unique understandings [106,107] and allowing in-depth exploration of complex phenomena [108].”
Method“It happened to be the perfect thing”: experiences of generative AI chatbots for mental health
Siddals, S., Torous, J., & Coxon, A. (2024) · npj Mental Health Research · doi:10.1038/s44184-024-00097-4 · Cited by 241 · see citing works
Moorhouse, B. L., Wan, Y., Wu, C., Kohnke, L., Ho, T. Y., & Kwong, T. (2024) · System · doi:10.1016/j.system.2024.103399 · Cited by 228 · see citing works
General Practitioners’ Attitudes Toward Artificial Intelligence–Enabled Systems: Interview Study
Buck, C., Doctor, E., Hennrich, J., Jöhnk, J., & Eymann, T. (2022) · Journal of Medical Internet Research · doi:10.2196/28916 · Cited by 147 · see citing works
Assessing the Effectiveness of ChatGPT in Delivering Mental Health Support: A Qualitative Study
Alanezi, F. (2024) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s447368 · Cited by 139 · see citing works
Yang, T.-C., Hsu, Y.-C., & Wu, J.-Y. (2025) · Interactive Learning Environments · doi:10.1080/10494820.2025.2450659 · Cited by 80 · see citing works
Leading with AI in critical care nursing: challenges, opportunities, and the human factor
Hassan, E. A., & El-Ashry, A. M. (2024) · BMC Nursing · doi:10.1186/s12912-024-02363-4 · Cited by 72 · see citing works
Malik, A., Khan, M. L., & Hussain, K. (2023) · doi:10.2139/ssrn.4413516 · Cited by 59 · see citing works
Cho, H., Nguyen, O. T., Weaver, M., Pruitt, J., Marcelle, C., Salloum, R. G., & Keenan, G. (2024) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocae239 · Cited by 55 · see citing works
Blake, H., Gupta, A., Javed, M., Wood, B., Knowles, S., Coyne, E., & Cooper, J. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18073626 · Cited by 53 · see citing works
Malik, A., Khan, M. L., Hussain, K., Qadir, J., & Tarhini, A. (2025) · Interactive Learning Environments · doi:10.1080/10494820.2024.2409407 · Cited by 57 · see citing works
Moldt, J.-A., Festl-Wietek, T., Fuhl, W., Zabel, S., Claassen, M., Wagner, S., Nieselt, K., & Herrmann-Werner, A. (2024) · JMIR Medical Education · doi:10.2196/58355 · Cited by 47 · see citing works
Peng, M. L., Wickersham, J. A., Altice, F. L., Shrestha, R., Azwa, I., Zhou, X., Halim, M. A. A., Ikhtiaruddin, W. M., Tee, V., Kamarulzaman, A., et al. (2022) · JMIR Formative Research · doi:10.2196/42055 · Cited by 44 · see citing works
Strategic Invisibility: How Creators Manage the Risks and Constraints of Online Hyper(In)Visibility
Stegeman, H. M., Are, C., & Poell, T. (2024) · Social Media + Society · doi:10.1177/20563051241244674 · Cited by 45 · see citing works
“Yet, as semi-structured interviews allow (Galletta, 2013; Kallio et al., 2016), topics from COVID-19, parenting, financial discrimination, and crucially negotiations of visibility were also explored.”
S-LCA of lithium mining in Chile and its potential impacts on water and the local community
Roche, L., Link, A., Marinova, S., Coroama, V., & Finkbeiner, M. (2025) · The International Journal of Life Cycle Assessment · doi:10.1007/s11367-024-02378-8 · Cited by 32 · see citing works
“The interview questions were developed for use in semi-structured interviews, meaning there is the opportunity to reorder questions and have more flexibility and dialogue during the interviews (Kallio et al. 2016).”
Factors influencing patients’ engagement with ChatGPT for accessing health-related information
Alanezi, F. (2024) · Critical Public Health · doi:10.1080/09581596.2024.2348164 · Cited by 26 · see citing works
Exploring Community-Based Suicide Prevention in the Context of Rural Australia: A Qualitative Study
Grattidge, L., Hoang, H., Mond, J., Lees, D., Visentin, D., & Auckland, S. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20032644 · Cited by 25 · see citing works
Tully, S. M., Bucci, S., & Berry, K. (2023) · Journal of Psychiatric and Mental Health Nursing · doi:10.1111/jpm.12855 · Cited by 24 · see citing works
Fagbemi, T., Dosumu, O., Adigun, R., Nakpodia, F., & Sakariyahu, R. (2025) · Financial Accountability & Management · doi:10.1111/faam.12408 · Cited by 13 · see citing works
Roos, C. R., Kiluk, B., Carroll, K. M., Bricker, J. B., Mun, C. J., Sala, M., Kirouac, M., Stein, E., John, M., Palmer, R., et al. (2024) · Annals of Medicine · doi:10.1080/07853890.2024.2315228 · Cited by 12 · see citing works
Abbate, C., Trimarchi, P. D., Inglese, S., Tomasini, E., Bagarolo, R., Giunco, F., & Cesari, M. (2021) · Applied Neuropsychology Adult · doi:10.1080/23279095.2019.1630626 · Cited by 10 · see citing works
Medication self-management among older adults with cognitive frailty
Ibrahim, N. A., Wong, Y. Y., Lean, Q. Y., Ramasamy, K., Lim, S. M., Tan, M. P., & Abdul Majeed, A. B. (2024) · Research in Social and Administrative Pharmacy · doi:10.1016/j.sapharm.2023.11.001 · Cited by 10 · see citing works
Choi, K. Y., Wu, C., & Moorhouse, B. L. (2025) · Technology in Language Teaching & Learning · doi:10.29140/tltl.v7n3.102516 · Cited by 13 · see citing works
AI Act high-risk AI compliance challenge and industry impact: A multiple case study
Wagner, M., Song, Q., Borg, M., Engström, E., & Lysek, M. (2026) · Information and Software Technology · doi:10.1016/j.infsof.2026.108067 · Cited by 6 · see citing works
The four-day workweek in Australia: insights from early adopters of the 100:80:100 model
Hopkins, J., Bardoel, E. A., & Djurkovic, N. (2026) · Humanities and Social Sciences Communications · doi:10.1057/s41599-026-07536-x · Cited by 2 · see citing works
“…this investigation, as they enable participants to provide a wide range of in-depth responses, yielding the sort of rich data needed for analysis (Kallio et al., 2016), while allowing the interviewer to improvise and follow up in real time on speci fi c and novel information (Rubin and Rubin,…”
Department of Education Management, P. A. C. E., Letuma, M. C., Dlamini, M. E., & Department of Curriculum Studies and Higher Education, U. O. F. S. (2025) · International Journal of Educational Management & Development Studies · doi:10.53378/ijemds.353284 · Cited by 1 · see citing works
Pervez, A., Masrani, T., & Pemberton, E. (2026) · School Psychology International · doi:10.1177/01430343261422416
“A semi-structured format was chosen to support depth and fl exibility while maintaining consistency across core topics (Kallio et al., 2016).”
- Authors
- Kallio, H., Pietilä, A., Johnson, M., & Kangasniemi, M.
- Affiliations
- University of Eastern Finland (FI)
- University of Salford (GB)
- Corresponding author
- Kallio, Hanna
- Venue
- Journal of Advanced Nursing
- Publisher
- Wiley
- Published
- 2016-06-23
- Volume
- 72
- Issue
- 12
- Pages
- 2954-2965
- ISSN
- 0309-2402 (ISSN-L)
- 1365-2648
- OpenAlex
- W2396339611
- Cited by
- 4,295
- References
- 39
- Citations by year
- 2026: 1154 · 2025: 888 · 2024: 730 · 2023: 528 · 2022: 419 · 2021: 277 · 2020: 163 · 2019: 79 · 2018: 31 · 2017: 14 · 2016: 2 · 2015: 1 · 2012: 1
- FWCI
- 15.85
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Advanced Nursing (publishedVersion)
- PubMed (publishedVersion)
- University of Salford Institutional Repository (University of Salford) (submittedVersion, cc-by)
- Funders
- Federation of Nurse Education
- Aleksanteri Mikkonen's Foundation
- Topics
- Social Sciences › Sociology and Political Science › Focus Groups and Qualitative Methods
- Social Sciences › Education › Qualitative Research Methods and Applications
- Social Sciences › Sociology and Political Science › Qualitative Research Methods and Ethics
- Keywords
- semi-structured interview guide, interview guide development, qualitative data collection, pilot testing, nursing research methodology
- MeSH terms
- Data Collection, Humans, Interviews as Topic, Learning, Research Design, Qualitative Research
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review