Criteria for the Selection of Materials for Implanted Electrodes
Abstract
There are four criteria that must be considered when choosing material for an implanted electrode: (1) tissue response, (2) allergic response, (3) electrode-tissue impedance, and (4) radiographic visibility. This paper discusses these four criteria and identifies the materials that are the best candidates for such electrodes. For electrodes that make ohmic contact with tissues: gold, platinum, platinum-iridium, tungsten, and tantalum are good candidates. The preferred insulating materials are polyimide and glass. The characteristics of stimulator output circuits and the importance of the bidirectional waveform in relation to electrode decomposition are discussed. The paper concludes with an analysis, the design criteria, and the special properties and materials for capacitive recording and stimulating electrodes.
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Good candidates for ohmic electrode-tissue contacts are gold, platinum, platinum-iridium, tungsten, and tantalum.
“Good candidates for ohmic electrode-tissue contacts are gold, platinum (Pt), platinum-iridium, tungsten, and tantalum”
From A critical review of interfaces with the peripheral nervous system for the control of neuroprostheses and hybrid bionic systems (2005) · cites this paper as Geddes and Roeder, 2003
A foreign body response over contacts within excitable tissue will increase separation between the electrode and target tissue, leading to a raised stimulation threshold proportional to scar tissue thickness and a drop in recording sensitivities.
“The electrical interface must be stable as a foreign body response over the contacts within excitable tissue will increase the separation between the electrode and the target tissue, leading to a raised stimulation threshold that is proportional to the scar tissue thickness and a drop in recording sensitivities (Geddes and Roeder 2003).”
From Peripheral nerve bionic interface: a review of electrodes (2019) · cites this paper as Geddes and Roeder 2003
Encapsulation materials for implants need to be both biocompatible and resistant to bio-dissolution.
“Encapsulation materials which are conventionally electrical insulators need to be both biocompatible and resistant to bio-dissolution (Geddes and Roeder 2003; Joung 2013).”
From Peripheral nerve bionic interface: a review of electrodes (2019) · cites this paper as Geddes and Roeder 2003
Cardiac pacemakers' threshold current is established during surgery, then doubled to account for the expected bioresponse to the implant.
“Cardiac pacemakers' threshold current is established during surgery, then doubled to account for the expected bioresponse to the implant (Geddes and Roeder 2003).”
From Peripheral nerve bionic interface: a review of electrodes (2019) · cites this paper as Geddes and Roeder 2003
Stimulating without a DC bias reduces electro-decomposition of electrical contacts, and bi-phasic pulses with a zero-net-charge have a similar response.
“The longevity of the implant can be further improved through the operation of the electrodes, stimulating without a DC bias will reduce electro-decomposition of the electrical contacts, whilst bi-phasic pulses with a zero-net-charge have a similar response (Geddes and Roeder 2003).”
From Peripheral nerve bionic interface: a review of electrodes (2019) · cites this paper as Geddes and Roeder 2003
Cites
Campbell, P. K., Jones, K. E., Huber, R. J., Horch, K. W., & Normann, R. A. (1991) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.83588 · Cited by 881 · see citing works
Tungsten Microelectrode for Recording from Single Units
Hubel, D. H. (1957) · Science · doi:10.1126/science.125.3247.549 · Cited by 852 · see citing works
Principles of Applied Biomedical Instrumentation.
(1975) · Annals of Internal Medicine · doi:10.7326/0003-4819-83-6-924_2 · Cited by 561 · see citing works
An Integrated-Circuit Approach to Extracellular Microelectrodes
Wise, K. D., Angell, J. B., & Starr, A. (1970) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.1970.4502738 · Cited by 544 · see citing works
DETERMINATION OF BIOLOGICAL IMPEDANCES
Schwan, H. P. (1963) · Elsevier eBooks · doi:10.1016/b978-1-4831-6743-5.50013-7 · Cited by 439 · see citing works
Brummer, S. B., & Turner, M. J. (1977) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.1977.326218 · Cited by 360 · see citing works
A glass/silicon composite intracortical electrode array
Jones, K. E., Campbell, P. K., & Normann, R. A. (1992) · Annals of Biomedical Engineering · doi:10.1007/bf02368134 · Cited by 354 · see citing works
Brief, Noninjurious Electric Waveform for Stimulation of the Brain
Lilly, J. C., Hughes, J. R., Alvord, E. C., & Galkin, T. W. (1955) · Science · doi:10.1126/science.121.3144.468 · Cited by 287 · see citing works
Electrodes and the measurement of bioelectric events
Geddes, L. A. (1972) · Medical Entomology and Zoology · Cited by 276 · see citing works
Self-citationHistorical evolution of circuit models for the electrode-electrolyte interface
Geddes, L. A. (1997) · Annals of Biomedical Engineering · doi:10.1007/bf02738534 · Cited by 222 · see citing works
Self-citationBiocompatibility of silicon‐based electrode arrays implanted in feline cortical tissue
Schmidt, S., Horch, K., & Normann, R. A. (1993) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820271106 · Cited by 182 · see citing works
Histopathological evaluation of materials implanted in the cerebral cortex
Stensaas, S. S., & Stensaas, L. J. (1978) · Acta Neuropathologica · doi:10.1007/bf00689766 · Cited by 177 · see citing works
Capacitive Electrocardiographic and Bioelectric Electrodes
López, A., & Richardson, P. C. (1969) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.1969.4502613 · Cited by 143 · see citing works
Brain tissue reaction to some chronically implanted metals
Dymond, A. M., Le, K., Jurist, J. M., & Crandall, P. H. (1970) · Journal of neurosurgery · doi:10.3171/jns.1970.33.5.0574 · Cited by 140 · see citing works
The impedance of stainless-steel electrodes
Geddes, L. A., Costa, C., & Wise, G. L. (1971) · Medical & Biological Engineering & Computing · doi:10.1007/bf02474708 · Cited by 112 · see citing works
Self-citationThe polarization impedance of common electrode metals operated at low current density
Ragheb, T., & Geddes, L. A. (1991) · Annals of Biomedical Engineering · doi:10.1007/bf02368466 · Cited by 87 · see citing works
Self-citationHistopathological Changes Produced by Implanted Electrodes in Cat Brains
Collias, J. C., & Manuelidis, E. E. (1957) · Journal of neurosurgery · doi:10.3171/jns.1957.14.3.0302 · Cited by 68 · see citing works
An Evaluation of the Resistance to Electrolysis of Metals for Use in Biostimulation Microprobes
White, R. L., & Gross, T. J. (1974) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.1974.324339 · Cited by 56 · see citing works
Phagocytic and metabolic reactions to chronically implanted metal brain electrodes.
Babb, T. L., & Kupfer, W. (1984) · Experimental Neurology · doi:10.1016/0014-4886(84)90179-1 · Cited by 51 · see citing works
An approach to corrosion control during electrical stimulation
McHardy, J., Geller, D., & Brummer, S. B. (1977) · Annals of Biomedical Engineering · doi:10.1007/bf02364014 · Cited by 46 · see citing works
Histopathological studies of tissue reactions to various metals implanted in cat brains.
Robinson, F. R., & Johnson, M. T. (1961) · PubMed · Cited by 41 · see citing works
Bickford, R. G., FISCHER, G., & Sayre, G. P. (1957) · PubMed · Cited by 41 · see citing works
Schaidach, M. (1971) · PubMed · Cited by 38 · see citing works
Geddes, L. A., & Roeder, R. (2001) · Annals of Biomedical Engineering · doi:10.1114/1.1349699 · Cited by 37 · see citing works
Self-citationRadovsky, A. S., & Vleet, J. F. V. (1989) · American Heart Journal · doi:10.1016/0002-8703(89)90408-0 · Cited by 37 · see citing works
Some new electrode techniques for long-term physiologic monitoring.
Pc, R., Coombs, F. K., & Adams, R. M. (1968) · PubMed · Cited by 31 · see citing works
Titannitrid-Herzschrittmacher-Elektroden - Pacemaker Electrodes Made of Titanium Nitride
Schaldach, M., Hubmann, M., Hardt, R., & Weikl, A. (1989) · Biomedizinische Technik/Biomedical Engineering · doi:10.1515/bmte.1989.34.7-8.185 · Cited by 20 · see citing works
Aronson, S., & Geddes, L. A. (1985) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.1985.325650 · Cited by 16 · see citing works
Self-citationTHE PAUCITY OF DEMONSTRABLE BRAIN DAMAGE FOLLOWING INTRACEREBRAL ELECTROGRAPHY: REPORT OF CASE
Dodge, H. W., Petersen, M. C., Sem-Jacobsen, C. W., Sayre, G. P., & Bickford, R. G. (1955) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(26)01696-4 · Cited by 14 · see citing works
Stimulation with capacitor electrodes
Geddes, L. A., Hinds, M., & Foster, K. S. (1987) · Medical & Biological Engineering & Computing · doi:10.1007/bf02447440 · Cited by 2 · see citing works
Self-citation
Flagged first, then by citations
1 of the 31 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Navarro, X., Krueger, T. B., Lago, N., Micera, S., Stieglitz, T., & Dario, P. (2005) · Journal of the Peripheral Nervous System · doi:10.1111/j.1085-9489.2005.10303.x · Cited by 845 · see citing works
Next-generation probes, particles, and proteins for neural interfacing
Rivnay, J., Wang, H., Fenno, L., Deisseroth, K., & Malliaras, G. G. (2017) · Science Advances · doi:10.1126/sciadv.1601649 · Cited by 514 · see citing works
Boehler, C., Carli, S., Fadiga, L., Stieglitz, T., & Asplund, M. (2020) · Nature Protocols · doi:10.1038/s41596-020-0389-2 · Cited by 311 · see citing works
Prasad, A., Xue, Q.-S., Sankar, V., Nishida, T., Shaw, G., Streit, W. J., & Sanchez, J. C. (2012) · Journal of Neural Engineering · doi:10.1088/1741-2560/9/5/056015 · Cited by 298 · see citing works
Organic electrode coatings for next-generation neural interfaces
Robles, U. A. A., Woolley, A. J., Poole-Warren, L. A., Lovell, N. H., & Green, R. A. (2014) · Frontiers in Neuroengineering · doi:10.3389/fneng.2014.00015 · Cited by 255 · see citing works
Functional Electrical Stimulation and Spinal Cord Injury
Ho, C., Triolo, R. J., Elias, A. L., Kilgore, K. L., DiMarco, A. F., Bogie, K. M., Vette, A. H., Audu, M. L., Kobetic, R., Chang, S. R., et al. (2014) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2014.05.001 · Cited by 205 · see citing works
Wilks, S. J. (2009) · Frontiers in Neuroengineering · doi:10.3389/neuro.16.007.2009 · Cited by 191 · see citing works
Liang, Q., Xia, X., Sun, X., Yu, D., Huang, X., Han, G., Mugo, S. M., Chen, W., & Zhang, Q. M. (2022) · Advanced Science · doi:10.1002/advs.202201059 · Cited by 186 · see citing works
Abiotic-biotic characterization of Pt/Ir microelectrode arrays in chronic implants
Prasad, A., Xue, Q.-S., Dieme, R., Sankar, V., Mayrand, R. C., Nishida, T., Streit, W. J., & Sanchez, J. C. (2014) · Frontiers in Neuroengineering · doi:10.3389/fneng.2014.00002 · Cited by 178 · see citing works
Biointegrated and Wirelessly Powered Implantable Brain Devices: A Review
Das, R., Moradi, F., & Heidari, H. (2020) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2020.2966920 · Cited by 171 · see citing works
Nanofabricated Neural Probes for Dense 3-D Recordings of Brain Activity
Rios, G., Lubenov, E. V., Chi, D., Roukes, M. L., & Siapas, A. G. (2016) · Nano Letters · doi:10.1021/acs.nanolett.6b02673 · Cited by 157 · see citing works
Thompson, G. J., Pan, W., Magnuson, M. E., Jaeger, D., & Keilholz, S. D. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.09.029 · Cited by 160 · see citing works
Vomero, M., Castagnola, E., Ciarpella, F., Maggiolini, E., Goshi, N., Zucchini, E., Carli, S., Fadiga, L., Kassegne, S., & Ricci, D. (2017) · Scientific Reports · doi:10.1038/srep40332 · Cited by 159 · see citing works
Wei, X. F., & Grill, W. M. (2005) · Journal of Neural Engineering · doi:10.1088/1741-2560/2/4/010 · Cited by 154 · see citing works
Pulsed laser versus electrical energy for peripheral nerve stimulation
Wells, J. D., Konrad, P. E., Kao, C., Jansen, D., & Mahadevan-Jansen, A. M. (2007) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2007.03.016 · Cited by 156 · see citing works
A review for the peripheral nerve interface designer
Larson, C. E., & Meng, E. (2020) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2019.108523 · Cited by 133 · see citing works
A review of electrodes for the electrical brain signal recording
Im, C., & Seo, J.-M. (2016) · Biomedical Engineering Letters · doi:10.1007/s13534-016-0235-1 · Cited by 141 · see citing works
The Argo: a high channel count recording system for neural recording <i>in vivo</i>
Sahasrabuddhe, K., Khan, A. A., Singh, A. P., Stern, T. M., Ng, Y., Tadić, A., Orel, P., LaReau, C., Pouzzner, D., Nishimura, K., et al. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/abd0ce · Cited by 124 · see citing works
A platinum–chromium steel for cardiovascular stents
O’Brien, B., Stinson, J. S., Larsen, S. R., Eppihimer, M. J., & Carroll, W. M. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.01.146 · Cited by 131 · see citing works
The Future of Neuroimplantable Devices: A Materials Science and Regulatory Perspective
Obidin, N., Tasnim, F., & Dagdeviren, C. (2020) · Advanced Materials · doi:10.1002/adma.201901482 · Cited by 126 · see citing works
Lee, J. H., Kim, H., Kim, J. H., & Lee, S. (2016) · Lab on a Chip · doi:10.1039/c5lc00842e · Cited by 124 · see citing works
Recent Progress on Microelectrodes in Neural Interfaces
Kim, G. H., Kim, K., Lee, E., An, T., Choi, W., Lim, G., & Shin, J. H. (2018) · Materials · doi:10.3390/ma11101995 · Cited by 121 · see citing works
Interfaces with the peripheral nervous system for the control of a neuroprosthetic limb: a review
Yildiz, K. A., Shin, A. Y., & Kaufman, K. R. (2020) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-020-00667-5 · Cited by 113 · see citing works
Invasive Intraneural Interfaces: Foreign Body Reaction Issues
Lotti, F., Ranieri, F., Vadalà, G., Zollo, L., & Pino, G. D. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00497 · Cited by 117 · see citing works
Composite biomolecule/PEDOT materials for neural electrodes
Asplund, M., von Holst, H., & Inganäs, O. (2008) · Biointerphases · doi:10.1116/1.2998407 · Cited by 109 · see citing works
The sinusoidal probe: a new approach to improve electrode longevity
Sohal, H. S., Jackson, A., Jackson, R., Clowry, G. J., Vassilevski, K. V., O’Neill, A., & Baker, S. N. (2014) · Frontiers in Neuroengineering · doi:10.3389/fneng.2014.00010 · Cited by 104 · see citing works
Arle, J. E., Mei, L., Carlson, K. W., & Shils, J. L. (2016) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.12436 · Cited by 105 · see citing works
Optically mediated nerve stimulation: Identification of injury thresholds
Wells, J. D., Thomsen, S., Whitaker, P., Jansen, D., Kao, C., Konrad, P. E., & Mahadevan-Jansen, A. M. (2007) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20522 · Cited by 105 · see citing works
Applications of bioimpedance measurement techniques in tissue engineering
Amini, M., Hisdal, J., & Kalvøy, H. (2018) · Journal of Electrical Bioimpedance · doi:10.2478/joeb-2018-0019 · Cited by 99 · see citing works
Nanotechnology and Nanomaterials for Improving Neural Interfaces
Wang, M., Mi, G., Shi, D., Bassous, N. J., Hickey, D. J., & Webster, T. J. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201700905 · Cited by 97 · see citing works
Electrode Materials for Chronic Electrical Microstimulation
Zheng, X. S., Tan, C., Castagnola, E., & Cui, X. T. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202100119 · Cited by 86 · see citing works
Sung, C., Jeon, W., Nam, K. S., Kim, Y., Butt, H., & Park, S. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb00872a · Cited by 85 · see citing works
Rothschild, R. M. (2010) · Frontiers in Neuroengineering · doi:10.3389/fneng.2010.00112 · Cited by 85 · see citing works
Chang, Y.-C., Cracchiolo, M., Ahmed, U., Mughrabi, I. T., Gabalski, A. H., Daytz, A. E., Rieth, L. W., Becker, L. B., Datta, T., Al‐Abed, Y., et al. (2020) · Brain stimulation · doi:10.1016/j.brs.2020.09.002 · Cited by 79 · see citing works
Insect–Machine Interface Based Neurocybernetics
Bozkurt, A. Y., Gilmour, R. F., Sinha, A., Stern, D., & Lal, A. (2009) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2009.2015460 · Cited by 77 · see citing works
Neural interfaces engineered via micro- and nanostructured coatings
Chen, N., Tian, L., Patil, A. C., Peng, S., Yang, I. H., Thakor, N. V., & Ramakrishna, S. (2017) · Nano Today · doi:10.1016/j.nantod.2017.04.007 · Cited by 74 · see citing works
Short‐duration, DC electrical stimulation increases chick embryo DRG neurite outgrowth
Wood, M. D., & Willits, R. K. (2006) · Bioelectromagnetics · doi:10.1002/bem.20214 · Cited by 74 · see citing works
Neural interfaces by hydrogels
Sheng, H., Wang, X., Kong, N., Wang, X., Yang, H., Wu, X., Wu, K., Li, C., Hu, J. Q., Tang, J., et al. (2019) · Extreme Mechanics Letters · doi:10.1016/j.eml.2019.100510 · Cited by 74 · see citing works
Piallat, B., Chabardès, S., Devergnas, A. D., Torres-Martinez, N., Allain, M., Barrat, E., & Benabid, A. L. (2009) · Neurosurgery · doi:10.1227/01.neu.0000336331.88559.cf · Cited by 73 · see citing works
Peripheral nerve bionic interface: a review of electrodes
Russell, C., Roche, A. D., & Chakrabarty, S. (2019) · International Journal of Intelligent Robotics and Applications · doi:10.1007/s41315-019-00086-3 · Cited by 67 · see citing works
Direct current electrocorticography for clinical neuromonitoring of spreading depolarizations
Hartings, J. A., Li, C., Hinzman, J. M., Shuttleworth, C. W., Ernst, G. L., Dreier, J. P., Wilson, J. A., Andaluz, N. O., Foreman, B. P., & Carlson, A. P. (2016) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x16653135 · Cited by 69 · see citing works
Advances in Carbon-Based Microfiber Electrodes for Neural Interfacing
Hejazi, M., Tong, W., Ibbotson, M. R., Prawer, S., & Garrett, D. J. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.658703 · Cited by 73 · see citing works
Han, W. B., Yang, S. M., Rajaram, K., & Hwang, S. (2021) · Advanced Sustainable Systems · doi:10.1002/adsu.202100075 · Cited by 68 · see citing works
An Effective Method for Acute Vagus Nerve Stimulation in Experimental Inflammation
Caravaca, A. S., Gallina, A. L., Tarnawski, L., Tracey, K. J., Pavlov, V. A., Levine, Y. A., & Olofsson, P. S. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00877 · Cited by 68 · see citing works
Pennisi, C. P., Dolatshahi‐Pirouz, A., Foss, M., Chevallier, J., Fink, T., Zachar, V., Besenbacher, F., & Yoshida, K. (2011) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2011.02.028 · Cited by 66 · see citing works
Cassar, I. R., Yu, C., Sambangi, J., Lee, C. D., Whalen, J. J., Petrossians, A., & Grill, W. M. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.03.017 · Cited by 63 · see citing works
Gori, M., Vadalà, G., Giannitelli, S. M., Denaro, V., & Pino, G. D. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.659033 · Cited by 65 · see citing works
Wu, F., Im, M., & Yoon, E. (2011) · International Conference on Solid-State Sensors, Actuators and Microsystems · doi:10.1109/transducers.2011.5969356 · Cited by 62 · see citing works
Analysis of high-perimeter planar electrodes for efficient neural stimulation
Wei, X. F. (2009) · Frontiers in Neuroengineering · doi:10.3389/neuro.16.015.2009 · Cited by 61 · see citing works
High Density, Double-Sided, Flexible Optoelectronic Neural Probes With Embedded μLEDs
Reddy, J. W., Kimukin, I., Stewart, L. T., Ahmed, Z., Barth, A. L., Towe, E., & Chamanzar, M. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00745 · Cited by 55 · see citing works
Alahi, M. E. E., Liu, Y., Xu, Z., Wang, H., Wu, T., & Mukhopadhyay, S. C. (2021) · Materials Today Communications · doi:10.1016/j.mtcomm.2021.102853 · Cited by 55 · see citing works
The use of tungsten as a chronically implanted material
Idil, A. S., & Donaldson, N. (2018) · Journal of Neural Engineering · doi:10.1088/1741-2552/aaa502 · Cited by 55 · see citing works
Implantable brain computer interface: Challenges to neurotechnology translation
Konrad, P. E., & Shanks, T. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.12.007 · Cited by 54 · see citing works
Flexible Split-Ring Electrode for Insect Flight Biasing Using Multisite Neural Stimulation
Tsang, W. M., Stone, A. L., Aldworth, Z., Hildebrand, J. G., Daniel, T. L., Akinwande, A. I., & Joel Voldman, B. (2010) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2010.2041778 · Cited by 54 · see citing works
Stretchable gold nanowire-based cuff electrodes for low-voltage peripheral nerve stimulation
Lienemann, S., Zötterman, J., Farnebo, S., & Tybrandt, K. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/abfebb · Cited by 48 · see citing works
Fabrication of Coaxial Wet‐Spun Graphene–Chitosan Biofibers
Mirabedini, A., Foroughi, J., Thompson, B., & Wallace, G. (2016) · Advanced Engineering Materials · doi:10.1002/adem.201500201 · Cited by 50 · see citing works
Use of Silk Proteins to Form Organic, Flexible, Degradable Biosensors for Metabolite Monitoring
Xu, M., Jiang, Y., Pradhan, S., & Yadavalli, V. K. (2019) · Frontiers in Materials · doi:10.3389/fmats.2019.00331 · Cited by 49 · see citing works
Polymeric C-shaped cuff electrode for recording of peripheral nerve signal
Xue, N., Sun, T., Tsang, W. M., Delgado-Martinez, I., Lee, S.-H., Sheshadri, S., Xiang, Z., Merugu, S., Gu, Y., Yen, S.-C., et al. (2015) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2015.01.006 · Cited by 48 · see citing works
Regenerative Scaffold Electrodes for Peripheral Nerve Interfacing
Clements, I. P., Mukhatyar, V. J., Srinivasan, A., Bentley, J. T., Andreasen, D. S., & Bellamkonda, R. V. (2012) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2012.2217352 · Cited by 46 · see citing works
Structural modifications in chronic microwire electrodes for cortical neuroprosthetics: a case study
Sanchez, J. C., Alba, N. A., Nishida, T., Batich, C. D., & Carney, P. R. (2006) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2006.875581 · Cited by 45 · see citing works
Living electrodes: Tissue engineering the neural interface
Green, R. A., Lim, K. S., Henderson, W. C., Hassarati, R. T., Martens, P. J., Lovell, N. H., & Poole-Warren, L. A. (2013) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2013.6611158 · Cited by 43 · see citing works
Electroactive biomimetic collagen-silver nanowire composite scaffolds
Wickham, A., Vagin, M. Y., Khalaf, H., Bertazzo, S., Hodder, P., Dånmark, S., Bengtsson, T., Altimiras, J., & Aili, D. (2016) · Nanoscale · doi:10.1039/c6nr02027e · Cited by 43 · see citing works
Bereuter, L., Kuenzle, T., Niederhäuser, T., Kučera, M., Obrist, D., Reichlin, T., Tanner, H., & Haeberlin, A. (2018) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2018.2886042 · Cited by 43 · see citing works
Cobo, A., Larson, C. E., Scholten, K., Miranda, J. A., Elyahoodayan, S., Song, D. B., Pikov, V., & Meng, E. F. (2018) · Journal of Microelectromechanical Systems · doi:10.1109/jmems.2018.2881908 · Cited by 43 · see citing works
In situ 3D printing of implantable energy storage devices
Krishnadoss, V., Kanjilal, B., Hesketh, A., Miller, C., Mugweru, A. M., Akbard, M., Khademhosseini, A., Leijten, J., & Noshadi, I. (2020) · Chemical Engineering Journal · doi:10.1016/j.cej.2020.128213 · Cited by 43 · see citing works
Responses of fibroblasts and glial cells to nanostructured platinum surfaces
Pennisi, C. P., Sevcencu, C., Dolatshahi‐Pirouz, A., Foss, M., Hansen, J. L., Larsen, A. N., Zachar, V., Besenbacher, F., & Yoshida, K. (2009) · Nanotechnology · doi:10.1088/0957-4484/20/38/385103 · Cited by 42 · see citing works
Myllymaa, S., Myllymaa, K., Korhonen, H., Töyräs, J., Jääskeläinen, J. E., Djupsund, K., Tanila, H., & Lappalainen, R. (2009) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2009.03.028 · Cited by 41 · see citing works
Decoding Electrophysiological Signals with Organic Electrochemical Transistors
Zhong, Y., Saleh, A., & Inal, S. (2021) · Macromolecular Bioscience · doi:10.1002/mabi.202100187 · Cited by 41 · see citing works
Babaroud, N. B., Palmar, M., Velea, A. I., Coletti, C., Weingärtner, S., Vos, F. M., Serdijn, W. A., Vollebregt, S., & Giagka, V. (2022) · Microsystems & Nanoengineering · doi:10.1038/s41378-022-00430-x · Cited by 40 · see citing works
Advances in Material‐Assisted Electromagnetic Neural Stimulation
Sun, Y., Zhifeng, X., Chen, B., Zhao, Y., & Dai, J. (2024) · Advanced Materials · doi:10.1002/adma.202400346 · Cited by 38 · see citing works
Living Synthelectronics: A New Era for Bioelectronics Powered by Synthetic Biology
Sun, J., Yang, R., Li, Q., Zhu, R., Jiang, Y., Zang, L., Zhang, Z., Tong, W., Zhao, H., Li, T., et al. (2024) · Advanced Materials · doi:10.1002/adma.202400110 · Cited by 37 · see citing works
System-on-Chip Considerations for Heterogeneous Integration of CMOS and Fluidic Bio-Interfaces
Datta, T., Smela, E., & Abshire, P. (2016) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2016.2522402 · Cited by 36 · see citing works
Galvanically Coupled Intrabody Communications for Medical Implants: A Unified Analytic Model
Teshome, A. K., Kibret, B., & Lai, D. T. H. (2016) · IEEE Transactions on Antennas and Propagation · doi:10.1109/tap.2016.2559519 · Cited by 36 · see citing works
Vardi, R., Goldental, A., Sardi, S., Sheinin, A., & Kanter, I. (2016) · Scientific Reports · doi:10.1038/srep36228 · Cited by 33 · see citing works
Topography and Coating of Platinum Improve the Electrochemical Properties and Neuronal Guidance
Schlie-Wolter, S., Deiwick, A., Fadeeva, E., Paasche, G., Lenarz, T., & Chichkov, B. N. (2013) · ACS Applied Materials & Interfaces · doi:10.1021/am3028487 · Cited by 32 · see citing works
Multi‐Electrode Array for Transcutaneous Lumbar Posterior Root Stimulation
Krenn, M. J., Hofstoetter, U. S., Danner, S. M., Minassian, K., & Mayr, W. (2015) · Artificial Organs · doi:10.1111/aor.12616 · Cited by 31 · see citing works
Integrated In Vivo Neural Imaging and Interface CMOS Devices: Design, Packaging, and Implementation
Ng, D. C., Nakagawa, T., Mizuno, T., Tokuda, T., Nunoshita, M., Tamura, H., Ishikawa, Y., Shiosaka, S., & Ohta, J. (2008) · IEEE Sensors Journal · doi:10.1109/jsen.2007.912921 · Cited by 30 · see citing works
Ng, D. C., Tamura, H., Mizuno, T., Tokuda, T., Nunoshita, M., Ishikawa, Y., Shiosaka, S., & Ohta, J. (2007) · Sensors and Actuators A Physical · doi:10.1016/j.sna.2007.11.020 · Cited by 30 · see citing works
New Perspectives on Neuroengineering and Neurotechnologies: NSF-DFG Workshop Report
Moritz, C. T., Ruther, P., Goering, S., Stett, A., Ball, T., Burgard, W., Chudler, E. H., & Rao, R. P. N. (2016) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2016.2543662 · Cited by 29 · see citing works
Flexible Hybrid Electronic Circuits and Systems
Schwartz, D. E., Rivnay, J., Whiting, G. L., Mei, P., Zhang, Y., Krusor, B. S., Kor, S., Daniel, G., Ready, S. E., Veres, J., et al. (2016) · IEEE Journal on Emerging and Selected Topics in Circuits and Systems · doi:10.1109/jetcas.2016.2612623 · Cited by 29 · see citing works
Myllymaa, S., Pirinen, S., Myllymaa, K., Suvanto, M., Pakkanen, T. A., Pakkanen, T. A., & Lappalainen, R. (2012) · Measurement Science and Technology · doi:10.1088/0957-0233/23/12/125701 · Cited by 28 · see citing works
Design and Fabrication of a Flexible Substrate Microelectrode Array for Brain Machine Interfaces
Patrick, E. E., Ordonez, M., Alba, N. A., Sanchez, J. C., & Nishida, T. (2006) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/iembs.2006.260581 · Cited by 28 · see citing works
Enhancing biocompatibility of the brain-machine interface: A review
Villa, J., Cury, J., Kessler, L., Tan, X., & Richter, C. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.08.034 · Cited by 29 · see citing works
Xue, N., Delgado-Martínez, I., Sun, J., Cheng, Y., & Liu, C. (2018) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2018.04.043 · Cited by 27 · see citing works
A novel neuromodulation strategy to enhance the prefrontal control to treat pain
Zhou, H., Zhang, Q., Martinez, E., Dale, J., Robinson, E. J., Huang, D., & Wang, J. (2019) · Molecular Pain · doi:10.1177/1744806919845739 · Cited by 27 · see citing works
Graphene Oxide–Based Nanomaterials: An Insight into Retinal Prosthesis
Yang, J., Yu, Z.-Y., Cheng, S.-J., Chung, J. H.-Y., Liu, X., Wu, C., Lin, S., & Chen, G. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21082957 · Cited by 26 · see citing works
Materials analyses and electrochemical impedance of implantable metal electrodes
Howlader, M. M. R., Alam, A. U., Sharma, R., & Deen, M. J. (2015) · Physical Chemistry Chemical Physics · doi:10.1039/c4cp05899b · Cited by 25 · see citing works
Diazonium-Based Anchoring of PEDOT on Pt/Ir Electrodes via Diazonium Chemistry
Chhin, D., Polcari, D., Bodart, C., Tomasello, G., Cicoira, F., & Schougaard, S. B. (2018) · Journal of The Electrochemical Society · doi:10.1149/2.0061812jes · Cited by 25 · see citing works
Electrode Failure: Tissue, Electrical, and Material Responses
Streit, W. J., Xue, Q., Prasad, A., Sankar, V., Knott, E. P., Dyer, A. L., Reynolds, J. R., Nishida, T., Shaw, G. P., & Sanchez, J. C. (2012) · IEEE Pulse · doi:10.1109/mpul.2011.2175632 · Cited by 25 · see citing works
Puckert, C., Tomaskovic‐Crook, E., Gambhir, S., Wallace, G. G., Crook, J. M., & Higgins, M. J. (2017) · Soft Matter · doi:10.1039/c7sm00335h · Cited by 25 · see citing works
Materials and devices for high‐density, high‐throughput micro‐electrocorticography arrays
Xie, Y., Peng, Y., Guo, J., Liu, M., Zhang, B., Yin, L., Ding, H., & Sheng, X. (2024) · Fundamental Research · doi:10.1016/j.fmre.2024.01.016 · Cited by 23 · see citing works
Khan, A. A., & Kim, J. (2024) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2024.116461 · Cited by 24 · see citing works
Silk Fibroin-Sheathed Conducting Polymer Wires as Organic Connectors for Biosensors
Jiang, Y., Xu, M., & Yadavalli, V. K. (2019) · Biosensors · doi:10.3390/bios9030103 · Cited by 24 · see citing works
The Role of Materials Biocompatibility for Functional Electrical Stimulation Applications
Plenk, H., Jr. (2011) · Artificial Organs · doi:10.1111/j.1525-1594.2011.01221.x · Cited by 24 · see citing works
Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
Chung, J. E., Joo, H. R., Smyth, C., Fan, J. L., Geaghan-Breiner, C., Liang, H., Liu, D. F., Roumis, D. K., Chen, S., Lee, K. Y., et al. (2019) · Journal of Visualized Experiments · doi:10.3791/59957 · Cited by 25 · see citing works
Microfabricated Cylindrical Multielectrodes for Neural Stimulation
Snow, S., Jacobsen, S. C., Wells, D., & Horch, K. W. (2006) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2005.862552 · Cited by 24 · see citing works
Stretchable Tissue‐Like Gold Nanowire Composites with Long‐Term Stability for Neural Interfaces
Seufert, L., ElMahmoudy, M., Theunis, C., Lienemann, S., Li, Y., Mohammadi, M., Boda, U., Carnicer‐Lombarte, A., Kroon, R., Persson, P. O. Å., et al. (2024) · Small · doi:10.1002/smll.202402214 · Cited by 23 · see citing works
Wang, X., Kim, J. H., Choi, Y. B., Kim, H.-H., & Kim, C.-J. (2019) · Korean Journal of Chemical Engineering · doi:10.1007/s11814-019-0278-y · Cited by 23 · see citing works
In Vivo Penetrating Microelectrodes for Brain Electrophysiology
Erofeev, A., Antifeev, I., Bolshakova, A. V., Борисович, Б. И., & Власова, О. Л. (2022) · Sensors · doi:10.3390/s22239085 · Cited by 24 · see citing works
The Argo: A 65,536 channel recording system for high density neural recording in vivoPreprint
Sahasrabuddhe, K., Khan, A. A., Singh, A., Stern, T. M., Ng, Y., Tadić, A., Orel, P., LaReau, C., Pouzzner, D., Nishimura, K. A., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.07.17.209403 · Cited by 20 · see citing works
- Authors
- Geddes, L. A., & Roeder, R.
- Affiliations
- Purdue University West Lafayette (US)
- Venue
- Annals of Biomedical Engineering
- Published
- 2003-07
- Volume
- 31
- Issue
- 7
- Pages
- 879-890
- ISSN
- 0090-6964 (ISSN-L)
- OpenAlex
- W1978696561
- Cited by
- 240
- References
- 31
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 12 · 2023: 8 · 2022: 13 · 2021: 18 · 2020: 19 · 2019: 21 · 2018: 20 · 2017: 15 · 2016: 19 · 2015: 11 · 2014: 18 · 2013: 7 · 2012: 8
- FWCI
- 0.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Biomedical Engineering (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Health Sciences › Medicine › Surgery › Orthopaedic implants and arthroplasty
- Keywords
- implanted electrodes, electrode materials, tissue reaction, allergic reactions, gold, platinum, tungsten, tantalum, polyimide, glass insulators
- MeSH terms
- Biocompatible Materials, Decision Support Techniques, Electrodes, Implanted, Electrophysiology, Equipment Design, Hypersensitivity, Materials Testing, Microelectrodes, Technology Assessment, Biomedical, Equipment Failure Analysis
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