Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Cited by (140)

Items 101–140 of 140

1. Intracellular localization of the BCL-2 family member BOK and functional implications
   Echeverry, N, Bachmann, D, Ke, F, Strasser, A, Simon, H U, Kaufmann, T · 2013 · Cell Death & Differentiation
2. Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis
   Huang, Kai, Zhang, Jingjing, O’Neill, Katelyn L., Gurumurthy, Channabasavaiah B., Quadros, Rolen M., Tu, Yaping, Luo, Xu · 2016 · Journal of Biological Chemistry
3. BCL-2 family member BOK promotes apoptosis in response to endoplasmic reticulum stress
   Carpio, Marcos A., Michaud, Michael, Zhou, Wenping, Fisher, Jill K., Walensky, Loren D., Katz, Samuel G. · 2015 · Proceedings of the National Academy of Sciences
4. A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes
   Thornborrow, Edward C, Patel, Sejal, Mastropietro, Anthony E, Schwartzfarb, Elissa M, Manfredi, James J · 2002 · Oncogene
5. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts
   Todorovicç, Viktor, Chen, Chih-Chiun, Hay, Nissim, Lau, Lester F. · 2005 · The Journal of Cell Biology
6. One-step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment
   Grav, Lise Marie, Lee, Jae Seong, Gerling, Signe, Kallehauge, Thomas Beuchert, Hansen, Anders Holmgaard, Kol, Stefan, Lee, Gyun Min, Pedersen, Lasse Ebdrup, Kildegaard, Helene Faustrup · 2015 · Biotechnology Journal
7. Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D
   Trincheri, N. F., Nicotra, G., Follo, C., Castino, R., Isidoro, C. · 2006 · Carcinogenesis
8. The role of apoptosis in megakaryocytes and platelets
   Kile, Benjamin T. · 2014 · British Journal of Haematology
9. Hsp70: Anti-apoptotic and Tumorigenic Protein
   Rérole, Anne-Laure, Jego, Gaëtan, Garrido, Carmen · 2011 · Methods in Molecular Biology
10. An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway
    Garner, Thomas P., Reyna, Denis E., Priyadarshi, Amit, Chen, Hui-Chen, Li, Sheng, Wu, Yang, Ganesan, Yogesh Tengarai, Malashkevich, Vladimir N., Cheng, Emily H., Gavathiotis, Evripidis · 2016 · Molecular Cell
11. Don't lose heart - therapeutic value of apoptosis prevention in the treatment of cardiovascular disease
    Reeve, Janice L. V., Duffy, Angela M., O'Brien, Timothy, Samali, Afshin · 2005 · Journal of Cellular and Molecular Medicine
12. Inhibition of Bak Activation by VDAC2 Is Dependent on the Bak Transmembrane Anchor
    Lazarou, Michael, Stojanovski, Diana, Frazier, Ann E., Kotevski, Aneta, Dewson, Grant, Craigen, William J., Kluck, Ruth M., Vaux, David L., Ryan, Michael T. · 2010 · Journal of Biological Chemistry
13. The Proapoptotic Factors Bax and Bak Regulate T Cell Proliferation through Control of Endoplasmic Reticulum Ca2+ Homeostasis
    Jones, Russell G., Bui, Thi, White, Carl, Madesh, Muniswamy, Krawczyk, Connie M., Lindsten, Tullia, Hawkins, Brian J., Kubek, Sara, Frauwirth, Kenneth A., Wang, Y. Lynn et al. · 2007 · Immunity
14. The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool
    Lindsten, Tullia, Golden, Jeffrey A., Zong, Wei-Xing, Minarcik, Jeremy, Harris, Marian H., Thompson, Craig B. · 2003 · The Journal of Neuroscience
15. Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy
    Lindner, Andreas U., Concannon, Caoimhín G., Boukes, Gerhardt J., Cannon, Mary D., Llambi, Fabien, Ryan, Deborah, Boland, Karen, Kehoe, Joan, McNamara, Deborah A., Murray, Frank et al. · 2013 · Cancer Research
16. NF-κB pathway controls mitochondrial dynamics
    Laforge, M, Rodrigues, V, Silvestre, R, Gautier, C, Weil, R, Corti, O, Estaquier, J · 2016 · Cell Death & Differentiation
17. WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death
    Venkatesan, Balachandar, Prabhu, Sumanth D., Venkatachalam, Kaliyamurthi, Mummidi, Srinivas, Valente, Anthony J., Clark, Robert A., Delafontaine, Patrice, Chandrasekar, Bysani · 2010 · Cellular Signalling
18. Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis
    Naghdi, Shamim, Várnai, Péter, Hajnóczky, György · 2015 · Proceedings of the National Academy of Sciences
19. Nutlin-3 protects kidney cells during cisplatin therapy by suppressing Bax/Bak activation
    Jiang, Man, Pabla, Navjotsin, Murphy, Robert F., Yang, Tianxin, Yin, Xiao-Ming, Degenhardt, Kurt, White, Eileen, Dong, Zheng · 2007 · Journal of Biological Chemistry
20. Hyperoxia-induced Apoptosis Does Not Require Mitochondrial Reactive Oxygen Species and Is Regulated by Bcl-2 Proteins
    Budinger, G. R. Scott, Tso, May, McClintock, David S., Dean, David A., Sznajder, Jacob I., Chandel, Navdeep S. · 2002 · Journal of Biological Chemistry
21. SARS-CoV-2 membrane protein causes the mitochondrial apoptosis and pulmonary edema via targeting BOK
    Yang, Yang, Wu, Yongjian, Meng, Xiaojun, Wang, Zhiying, Younis, Muhammad, Liu, Ye, Wang, Peihui, Huang, Xi · 2022 · Cell Death & Differentiation
22. Conformational Changes in BAK, a Pore-forming Proapoptotic Bcl-2 Family Member, upon Membrane Insertion and Direct Evidence for the Existence of BH3-BH3 Contact Interface in BAK Homo-oligomers
    Oh, Kyoung Joon, Singh, Pawan, Lee, Kyungro, Foss, Kelly, Lee, Shinyoub, Park, Minji, Lee, Steffi, Aluvila, Sreevidya, Park, Matthew, Singh, Puja et al. · 2010 · Journal of Biological Chemistry
23. Crossing paths: interactions between the cell death machinery and growth factor survival signals
    Brumatti, Gabriela, Salmanidis, Marika, Ekert, Paul G. · 2010 · Cellular and Molecular Life Sciences
24. Redox-Dependent Translocation of p53 to Mitochondria or Nucleus in Human Melanocytes after UVA- and UVB-Induced Apoptosis
    Wäster, Petra K., Öllinger, Karin M. · 2009 · Journal of Investigative Dermatology
25. Assembly of the Bak Apoptotic Pore
    Ma, Stephen, Hockings, Colin, Anwari, Khatira, Kratina, Tobias, Fennell, Stephanie, Lazarou, Michael, Ryan, Michael T., Kluck, Ruth M., Dewson, Grant · 2013 · Journal of Biological Chemistry
26. Organization of the Mitochondrial Apoptotic BAK Pore
    Aluvila, Sreevidya, Mandal, Tirtha, Hustedt, Eric, Fajer, Peter, Choe, Jun Yong, Oh, Kyoung Joon · 2014 · Journal of Biological Chemistry
27. Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak
    Einsele-Scholz, Stephanie, Malmsheimer, Silke, Bertram, Katrin, Stehle, Daniel, Johänning, Janina, Manz, Marianne, Daniel, Peter T., Gillissen, Bernhard F., Schulze-Osthoff, Klaus, Essmann, Frank · 2016 · Journal of Cell Science
28. Virulent Shigella flexneri Causes Damage to Mitochondria and Triggers Necrosis in Infected Human Monocyte-Derived Macrophages
    Koterski, James F., Nahvi, Massoumeh, Venkatesan, Malabi M., Haimovich, Beatrice · 2005 · Infection and Immunity
29. Induction of intrinsic apoptosis pathway in colon cancer HCT-116 cells by novel 2-substituted-5,6,7,8-tetrahydronaphthalene derivatives
    Gamal-Eldeen, Amira M., Hamdy, Nehal A., Abdel-Aziz, Hatem A., El-Hussieny, Enas A., Fakhr, Issa M.I. · 2014 · European Journal of Medicinal Chemistry
30. Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization
    Gama, V, Gomez, J A, Mayo, L D, Jackson, M W, Danielpour, D, Song, K, Haas, A L, Laughlin, M J, Matsuyama, S · 2009 · Cell Death & Differentiation
31. Kinsenoside Ameliorates Oxidative Stress-Induced RPE Cell Apoptosis and Inhibits Angiogenesis via Erk/p38/NF-κB/VEGF Signaling
    Luo, Xu, Gu, Shengjie, Zhang, Yujiao, Zhang, Jianhong · 2018 · Frontiers in Pharmacology
32. Exercise protects against chronic restraint stress-induced oxidative stress in the cortex and hippocampus
    Gerecke, Kim M., Kolobova, Anna, Allen, Sarah, Fawer, Jessica L. · 2013 · Brain Research
33. MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria
    Tan, Chong Teik, Zhou, Qi-Ling, Su, Yu-Chin, Fu, Nai Yang, Chang, Hao-Chun, Tao, Ran N., Sukumaran, Sunil K., Baksh, Shairaz, Tan, Yee-Joo, Sabapathy, Kanaga et al. · 2016 · Cell Reports
34. BIM deletion polymorphisms in Hispanic patients with non-small cell lung cancer carriers of EGFR mutations
    Cardona, Andrés F., on behalf of the CLICaP, Rojas, Leonardo, Wills, Beatriz, Arrieta, Oscar, Carranza, Hernán, Vargas, Carlos, Otero, Jorge, Corrales-Rodriguez, Luis, Martín, Claudio et al. · 2016 · Oncotarget
35. Rapamycin-enhanced mitomycin C-induced apoptotic death is mediated through the S6K1–Bad–Bak pathway in peritoneal carcinomatosis
    Song, X, Dilly, A-K, Kim, S-Y, Choudry, H A, Lee, Y J · 2014 · Cell Death & Disease
36. Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK
    Kawai, Kumi, Itoh, Takayuki, Itoh, Aki, Horiuchi, Makoto, Wakayama, Kouji, Bannerman, Peter, Garbern, James Y., Pleasure, David, Lindsten, Tullia · 2009 · European Journal of Neuroscience
37. Sulfasalazine reduces bile acid induced apoptosis in human hepatoma cells and perfused rat livers
    Rust, C, Bauchmuller, K, Bernt, C, Vennegeerts, T, Fickert, P, Fuchsbichler, A, Beuers, U · 2006 · Gut
38. Integration and Oligomerization of Bax Protein in Lipid Bilayers Characterized by Single Molecule Fluorescence Study
    Luo, Lu, Yang, Jun, Liu, Dongxiang · 2014 · Journal of Biological Chemistry
39. GRKs and β-Arrestins: “Gatekeepers” of Mitochondrial Function in the Failing Heart
    Sorriento, Daniela, Gambardella, Jessica, Fiordelisi, Antonella, Iaccarino, Guido, Illario, Maddalena · 2019 · Frontiers in Pharmacology
40. Differential mechanisms involved in RG-7388 and Nutlin-3 induced cell death in SJSA-1 osteosarcoma cells
    Natarajan, Umamaheswari, Venkatesan, Thiagarajan, Dhandayuthapani, Sivanesan, Dondapatti, Priya, Rathinavelu, Appu · 2020 · Cellular Signalling