Exercise protects against chronic restraint stress-induced oxidative stress in the cortex and hippocampus

Oxidants, antioxidants, and the degenerative diseases of aging.

Ames, B. N., Shigenaga, M. K., & Hagen, T. M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.17.7915 · Cited by 5,958 · see citing works

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Wei, M. C., Zong, W.-X., Cheng, E. H.-Y., Lindsten, T., Panoutsakopoulou, V., Ross, A. J., Roth, K. A., MacGregor, G. R., Thompson, C. B., & Korsmeyer, S. J. (2001) · Science · doi:10.1126/science.1059108 · Cited by 3,988 · see citing works

Neurodegenerative diseases and oxidative stress

Barnham, K. J., Masters, C. L., & Bush, A. I. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1330 · Cited by 3,683 · see citing works

Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

McGeer, P. L., Itagaki, S., Boyes, B. E., & McGeer, E. G. (1988) · Neurology · doi:10.1212/wnl.38.8.1285 · Cited by 2,990 · see citing works

Exercise: a behavioral intervention to enhance brain health and plasticity

Cotman, C. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02143-4 · Cited by 2,739 · see citing works

Oxidative stress in neurodegeneration: Cause or consequence?

Andersen, J. K. (2004) · Nature Medicine · doi:10.1038/nrn1434 · Cited by 1,869 · see citing works

Cortisol levels during human aging predict hippocampal atrophy and memory deficits

Lupien, S. J., de Leon, M., de Santi, S., Convit, A., Tarshish, C., Nair, N. P. V., Thakur, M., McEwen, B. S., Hauger, R. L., & Meaney, M. J. (1998) · Nature Neuroscience · doi:10.1038/271 · Cited by 1,653 · see citing works

Cardiovascular fitness, cortical plasticity, and aging

Colcombe, S. J., Kramer, A. F., Erickson, K. I., Scalf, P., McAuley, E., Cohen, N. J., Webb, A., Jerome, G. J., Marquez, D. X., & Elavsky, S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400266101 · Cited by 1,648 · see citing works

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

Novack, D. V., Sorenson, C. M., Shutter, J. R., & Korsmeyer, S. J. (1993) · Cell · doi:10.1016/0092-8674(93)80065-m · Cited by 1,628 · see citing works

Physical activity and risk of cognitive impairment and dementia in elderly persons

Laurin, D., Verreault, R., Lindsay, J., MacPherson, K., & Rockwood, K. (2001) · Archives of Neurology · doi:10.1001/archneur.58.3.498 · Cited by 1,561 · see citing works

Microglia-specific localisation of a novel calcium binding protein, Iba1

Ito, D., Imai, Y., Ohsawa, K., Nakajima, K., Fukuuchi, Y., & Kohsaka, S. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(98)00040-0 · Cited by 1,476 · see citing works

Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains

Riederer, P., Sofic, E., Rausch, W., Schmidt, B., Reynolds, G. P., Jellinger, K., & Youdim, M. B. H. (1989) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1989.tb09150.x · Cited by 1,383 · see citing works

Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids

Yamagata, K., Andreasson, K. I., Kaufmann, W. E., Barnes, C. A., & Worley, P. F. (1993) · Neuron · doi:10.1016/0896-6273(93)90192-t · Cited by 1,224 · see citing works

Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging

Sapolsky, R., Krey, L., & McEwen, B. (1985) · The Journal of Neuroscience · doi:10.1523/jneurosci.05-05-01222.1985 · Cited by 1,129 · see citing works

Hippocampal damage associated with prolonged glucocorticoid exposure in primates

Sapolsky, R., Uno, H., Rebert, C., & Finch, C. (1990) · The Journal of Neuroscience · doi:10.1523/jneurosci.10-09-02897.1990 · Cited by 1,103 · see citing works

Exercise and brain neurotrophins

Neeper, S. A., Góauctemez-Pinilla, F., Choi, J., & Cotman, C. (1995) · Nature · doi:10.1038/373109a0 · Cited by 1,066 · see citing works

The acute effects of corticosteroids on cognition: integration of animal and human model studies

LUPIEN, S., & MCEWEN, B. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00004-0 · Cited by 1,024 · see citing works

Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain

Neeper, S. A., Gómez‐Pinilla, F., Choi, J., & Cotman, C. W. (1996) · Brain Research · doi:10.1016/0006-8993(96)00273-9 · Cited by 1,015 · see citing works

MICROGLIA AS MEDIATORS OF INFLAMMATORY AND DEGENERATIVE DISEASES

González-Scarano, F., & Baltuch, G. (1999) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.22.1.219 · Cited by 984 · see citing works

A Novel Geneiba1in the Major Histocompatibility Complex Class III Region Encoding an EF Hand Protein Expressed in a Monocytic Lineage

Imai, Y., Ibata, I., Ito, D., Ohsawa, K., & Kohsaka, S. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.1112 · Cited by 872 · see citing works

Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing's syndrome

Starkman, M. N., Gebarski, S. S., Berent, S., & Schteingart, D. E. (1992) · Biological Psychiatry · doi:10.1016/0006-3223(92)90079-f · Cited by 840 · see citing works

Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR

McGeer, P. L., Itagaki, S., Tago, H., & McGeer, E. G. (1987) · Neuroscience Letters · doi:10.1016/0304-3940(87)90696-3 · Cited by 836 · see citing works

Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity

Gómez-Pinilla, F., Ying, Z., Roy, R. R., Molteni, R., & Edgerton, V. R. (2002) · Journal of Neurophysiology · doi:10.1152/jn.00152.2002 · Cited by 724 · see citing works

Cyclo-Oxygenase-2 Gene Expression in Neurons Contributes to Ischemic Brain Damage

Nogawa, S., Zhang, F., Ross, M. E., & Iadecola, C. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-08-02746.1997 · Cited by 715 · see citing works

Selective Retention of Corticosterone by Limbic Structures in Rat Brain

McEwen, B. S., Weiss, J. M., & Schwartz, L. S. (1968) · Nature · doi:10.1038/220911a0 · Cited by 713 · see citing works

Inflammation as a causative factor in the aetiology of Parkinson's disease

Whitton, P. S. (2007) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0707167 · Cited by 625 · see citing works

Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses

Frank, M. G., Baratta, M. V., Sprunger, D. B., Watkins, L. R., & Maier, S. F. (2007) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2006.03.005 · Cited by 578 · see citing works

Oxidative mechanisms in nigral cell death in Parkinson's disease.

Jenner, P. G. (1998) · PubMed · doi:10.1002/mds.870131304 · Cited by 511 · see citing works

High, usual and impaired functioning in community-dwelling older men and women: Findings from the MacArthur Foundation Research Network on successful aging

Berkman, L. F., Seeman, T. E., Albert, M., Blazer, D. G., Kahn, R. L., Mohs, R. C., Finch, C. E., Schneider, E. L., Cotman, C. W., McClearn, G. E., et al. (1993) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(93)90112-e · Cited by 499 · see citing works

Decreasing xanthine oxidase‐mediated oxidative stress prevents useful cellular adaptations to exercise in rats

Gómez‐Cabrera, M. C., Borrás, C., Pallardó, F. V., Sastre, J., Ji, L. L., & Viña, J. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2004.080564 · Cited by 477 · see citing works

Inflammatory processes in Alzheimer's disease

McGeer, E. G., & McGeer, P. L. (2003) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(03)00124-6 · Cited by 473 · see citing works

Cerebral ischemia and inflammation

Iadecola, C., & Alexander, M. (2001) · Current Opinion in Neurology · doi:10.1097/00019052-200102000-00014 · Cited by 466 · see citing works

Brain‐Derived Neurotrophic Factor Protects Dopamine Neurons Against 6‐Hydroxydopamine and N‐Methyl‐4‐Phenylpyridinium Ion Toxicity: Involvement of the Glutathione System

Spina, M. B., Squinto, S. P., Miller, J. M., Lindsay, R. M., & Hyman, C. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb08880.x · Cited by 460 · see citing works

Glucocorticoid-induced impairment in declarative memory performance in adult humans

Newcomer, J., Craft, S., Hershey, T., Askins, K., & Bardgett, M. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-04-02047.1994 · Cited by 441 · see citing works

Patients with Alzheimer's disease have reduced activities in midlife compared with healthy control-group members

Friedland, R. P., Fritsch, T., Smyth, K. A., Koss, E., Lerner, A. J., Chen, C. H., Petot, G. J., & Debanne, S. M. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.061002998 · Cited by 438 · see citing works

Upregulation of bax protein levels in neurons following cerebral ischemia

Krajewski, S., Jk, M., Krajewska, M., Sikorska, M., Mj, M., & Reed, J. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-10-06364.1995 · Cited by 430 · see citing works

A mechanism for glucocorticoid toxicity in the hippocampus: increased neuronal vulnerability to metabolic insults

Sapolsky, R. (1985) · Journal of Neuroscience · doi:10.1523/jneurosci.05-05-01228.1985 · Cited by 403 · see citing works

Stress-induced elevation of glucocorticoids increases microglia proliferation through NMDA receptor activation

Nair, A., & Bonneau, R. H. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2005.09.012 · Cited by 392 · see citing works

Glutathione Depletion, Lipid Peroxidation and Mitochondrial Dysfunction Are Induced by Chronic Stress in Rat Brain

Madrigal, J. L. M. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00208-6 · Cited by 381 · see citing works

Chronic stress: Implications for neuronal morphology, function and neurogenesis

Joëls, M., Karst, H., Krugers, H. J., & Lucassen, P. J. (2007) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2007.04.001 · Cited by 381 · see citing works

Glucocortcoids mediate the stress-induced extracellular accumulation of glutamate

Moghaddam, B., Bolinao, M. L., Stein-Behrens, B., & Sapolsky, R. (1994) · Brain Research · doi:10.1016/0006-8993(94)91622-5 · Cited by 378 · see citing works

Regular exercise improves cognitive function and decreases oxidative damage in rat brain

Radak, Z. O., Kaneko, T., Tahara, S., Nakamoto, H., Pucsok, J. M., Sasvári, M., Nyakas, C. J., & Goto, S. (2001) · Neurochemistry International · doi:10.1016/s0197-0186(00)00063-2 · Cited by 373 · see citing works

Physical activity and the risk of Parkinson disease

Chen, H., Zhang, S. M., Schwarzschild, M. A., Hernán, M. A., & Ascherio, A. (2005) · Neurology · doi:10.1212/01.wnl.0000151960.28687.93 · Cited by 371 · see citing works

After Reaching Retirement Age Physical Activity Sustains Cerebral Perfusion and Cognition

Rogers, R. L., Meyer, J. S., & Mortel, K. F. (1990) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1990.tb03472.x · Cited by 368 · see citing works

Lipid peroxidation and scavenger enzymes during exercise: adaptive response to training

Alessio, H. M., & Goldfarb, A. H. (1988) · Journal of Applied Physiology · doi:10.1152/jappl.1988.64.4.1333 · Cited by 362 · see citing works

Physical activity–antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model

Russo-Neustadt, A., Ha, T., Ramirez, R., & Kesslak, J. P. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(00)00364-8 · Cited by 346 · see citing works

Inflammation in central nervous system injury.

Allan, S., & Rothwell, N. (2003) · Philosophical transactions of the Royal Society of London. Series B, Biological sciences · doi:10.1098/rstb.2003.1358 · Cited by 336 · see citing works

Effects of Exercise on Gene-Expression Profile in the Rat Hippocampus

Tong, L., Shen, H., Perreau, V. M., Balázs, R., & Cotman, C. W. (2001) · Neurobiology of Disease · doi:10.1006/nbdi.2001.0427 · Cited by 325 · see citing works

Regional Effects of Wheel Running and Environmental Enrichment on Cell Genesis and Microglia Proliferation in the Adult Murine Neocortex

Ehninger, D. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.8.845 · Cited by 314 · see citing works

Level of education and change in cognitive function in a community population of older persons

Evans, D. A., Beckett, L. A., Albert, M., Hebert, L. E., Scherr, P. A., Funkenstein, H. H., & Taylor, J. O. (1993) · Annals of Epidemiology · doi:10.1016/1047-2797(93)90012-s · Cited by 312 · see citing works

Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer’s disease

Matsuoka, Y., Picciano, M., Malester, B., LaFrancois, J., Zehr, C., Daeschner, J. M., Olschowka, J. A., Fonseca, M. I., O’Banion, M. K., Tenner, A. J., et al. (2001) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64085-0 · Cited by 303 · see citing works

Uptake of corticosterone by rat brain and its concentration by certain limbic structures

McEwen, B. S., Weiss, J. M., & Schwartz, L. S. (1969) · Brain Research · doi:10.1016/0006-8993(69)90096-1 · Cited by 296 · see citing works

Interaction between inducible nitric oxide synthase and cyclooxygenase-2 after cerebral ischemia

Nogawa, S., Forster, C. L., Zhang, F., Nagayama, M., Ross, M. E., & Iadecola, C. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.18.10966 · Cited by 295 · see citing works

Effects of Stress and Hippocampal NMDA Receptor Antagonism on Recognition Memory in RatsPreprint

Baker, K. B., & Kim, J. J. (2002) · Learning & Memory · doi:10.1101/lm.46102 · Cited by 292 · see citing works

β-Amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology

Apelt, J., & Schliebs, R. (2001) · Brain Research · doi:10.1016/s0006-8993(00)03176-0 · Cited by 287 · see citing works

Hippocampal volume, spectroscopy, cognition, and mood in patients receiving corticosteroid therapy

Brown, E. S., Woolston, D. J., Frol, A. B., Bobadilla, L., Khan, D. A., Hanczyc, M., Rush, A. J., Fleckenstein, J., Babcock, E. E., & Cullum, C. M. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.09.010 · Cited by 276 · see citing works

Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N -methyl- d -aspartic acid-receptors and phospholipase A 2

Miettinen, S., Fusco, F. R., Yrjänheikki, J., Keinänen, R., Hirvonen, T. J., Roivainen, R., Närhi, M. V. O., Hökfelt, T. G. M., & Koıstınaho, J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.12.6500 · Cited by 276 · see citing works

The effect of exercise training on oxidative damage of lipids, proteins, and DNA in rat skeletal muscle: evidence for beneficial outcomes

Radak, Z. O., Kaneko, T., Tahara, S., Nakamoto, H., Ohno, H., Sasvári, M., Nyakas, C. J., & Goto, S. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00038-6 · Cited by 273 · see citing works

Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression

Adlard, P. A., & Cotman, C. W. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2003.12.039 · Cited by 265 · see citing works

Chronic unpredictable stress impairs long‐term potentiation in rat hippocampal CA1 area and dentate gyrus <i>in vitro</i>

Alfarez, D. N., Joëls, M., & Krugers, H. J. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02622.x · Cited by 258 · see citing works

Chronic stress-induced acceleration of electrophysiologic and morphometric biomarkers of hippocampal aging

Kerr, D. S., Campbell, L., Applegate, M. D., Brodish, A., & Landfield, P. W. (1991) · Journal of Neuroscience · doi:10.1523/jneurosci.11-05-01316.1991 · Cited by 257 · see citing works

The effects of training and detraining on memory, neurotrophins and oxidative stress markers in rat brain

Radak, Z. O., Toldy, A., Szabo, Z., Siamilis, S., Nyakas, C. J., Silye, G., Jakus, J., & Goto, S. (2006) · Neurochemistry International · doi:10.1016/j.neuint.2006.02.004 · Cited by 254 · see citing works

Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?

Kesslak, J. P., So, V., Choi, J., Cotman, C. W., & Gómez‐Pinilla, F. (1998) · Behavioral Neuroscience · doi:10.1037//0735-7044.112.4.1012 · Cited by 253 · see citing works

Environmental enrichment in adulthood eliminates neuronal death in experimental Parkinsonism

Faherty, C. J., Shepherd, K. R., Herasimtschuk, A., & Smeyne, R. J. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.08.008 · Cited by 241 · see citing works

HPA axis and memory

Wolf, O. T. (2003) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/s1521-690x(02)00101-x · Cited by 225 · see citing works

Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?

Kesslak, J. P., So, V., Choi, J. J., et al. (1998) · Behavioral Neuroscience · doi:10.1037/0735-7044.112.4.1012 · Cited by 212 · see citing works

Can the brain be protected through exercise? Lessons from an animal model of parkinsonism☆

Smith, A. D., & Zigmond, M. J. (2003) · Experimental Neurology · doi:10.1016/j.expneurol.2003.08.017 · Cited by 209 · see citing works

Aging, stress and the hippocampus

Miller, D. B., & O’Callaghan, J. P. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.03.002 · Cited by 206 · see citing works

The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise

Adlard, P. A., Perreau, V. M., Engesser‐Cesar, C., & Cotman, C. W. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.03.058 · Cited by 202 · see citing works

Altered expression of BDNF and its high-affinity receptor TrkB in response to complex motor learning and moderate exercise

Klintsova, A. Y., Dickson, E., Yoshida, R., & Greenough, W. T. (2004) · Brain Research · doi:10.1016/j.brainres.2004.09.003 · Cited by 200 · see citing works

Induction of cytokines in glial cells surrounding cortical β‐amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology

Mehlhorn, G., Hollborn, M., & Schliebs, R. (2000) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(00)00012-5 · Cited by 199 · see citing works

Exercise training acts as a therapeutic strategy for reduction of the pathogenic phenotypes for Alzheimer's disease in an NSE/APPsw-transgenic model

Cho, Y. (1998) · International Journal of Molecular Medicine · doi:10.3892/ijmm_00000052 · Cited by 196 · see citing works

Repeated Restraint Stress Induces Oxidative Damage in Rat Hippocampus

Fontella, F. U., Siqueira, I. R., de Vasconcellos, A. P. S., Tabajara, Â. S., Netto, C. A., & Dalmaz, C. (2005) · Neurochemical Research · doi:10.1007/s11064-004-9691-6 · Cited by 195 · see citing works

Sex differences in cell proliferation, cell death and defensive behavior following acute predator odor stress in adult rats

Falconer, E. M., & Galea, L. A. M. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02542-3 · Cited by 192 · see citing works

Corticosterone Slowly Enhances Miniature Excitatory Postsynaptic Current Amplitude in Mice CA1 Hippocampal Cells

Karst, H., & Joëls, M. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00143.2005 · Cited by 183 · see citing works

Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor κB‐mediated mechanisms

Madrigal, J. L. M., Moro, M. A., Lizasoain, I., Lorenzo, P., Castrillo, A., Boscá, L., & Leza, J. C. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00108.x · Cited by 180 · see citing works

Corticosterone acutely prolonged N‐methyl‐ d ‐aspartate receptor‐mediated Ca2+ elevation in cultured rat hippocampal neurons

Takahashi, T., Kimoto, T., Tanabe, N., Hattori, T., Yasumatsu, N., & Kawato, S. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01251.x · Cited by 176 · see citing works

Exercise affects energy metabolism and neural plasticity-related proteins in the hippocampus as revealed by proteomic analysis

Ding, Q., Vaynman, S., Souda, P., Whitelegge, J. P., & Gomez‐Pinilla, F. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05026.x · Cited by 174 · see citing works

Chronic mild stress impairs cognition in mice: From brain homeostasis to behavior

Li, S., Wang, C., Wang, W., Dong, H., Hou, P., & Tang, Y. (2008) · Life Sciences · doi:10.1016/j.lfs.2008.02.010 · Cited by 163 · see citing works

MIF Expression in the Rat Brain: Implications for Neuronal Function

Bacher, M., Meinhardt, A., Lan, H. Y., Dhabhar, F. S., Mu, W., Metz, C. N., Chesney, J. A., Gemsa, D., Donnelly, T. M., Atkins, R. C., et al. (1998) · Molecular Medicine · doi:10.1007/bf03401919 · Cited by 162 · see citing works

Glial cell reactions in neurodegenerative diseases: pathophysiology and therapeutic interventions.

McGeer, P. L., & McGeer, E. G. (1998) · PubMed · Cited by 157 · see citing works

Deprived of habitual running, rats downregulate BDNF and TrkB messages in the brain

Widenfalk, J., Olson, L., & Thorén, P. (1999) · Neuroscience Research · doi:10.1016/s0168-0102(99)00051-6 · Cited by 156 · see citing works

Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain

Madrigal, J. L. M., Moro, M. A., Lizasoain, I., Lorenzo, P., Fernández, A. P., Rodrigo, J., Boscá, L., & Leza, J. C. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300187 · Cited by 155 · see citing works

Glucocorticoid Toxicity in the Hippocampus

Sapolsky, R. M. (2008) · Neuroendocrinology · doi:10.1159/000124561 · Cited by 150 · see citing works

Effects of exercise on brain function: role of free radicals

Radak, Z. O., Kumagai, S., Taylor, A. W., Naıto, H., & Goto, S. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h07-081 · Cited by 141 · see citing works

Exercise, antidepressant treatment, and BDNF mRNA expression in the aging brain

Garza, A. A., Ha, T., Garcia, C., Chen, M. J., & Russo‐Neustadt, A. A. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2003.10.020 · Cited by 138 · see citing works

Muscle soreness-induced reduction in force generation is accompanied by increased nitric oxide content and DNA damage in human skeletal muscle

Radak, Z. O., Pucsok, J. M., Mecseki, S., Csont, T., & Ferdinandy, P. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00309-8 · Cited by 135 · see citing works

Exercise activates the phosphatidylinositol 3-kinase pathway

Chen, M. J., & Russo‐Neustadt, A. A. (2005) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.12.001 · Cited by 132 · see citing works

Exercise Induces Myonuclear Ubiquitination and Apoptosis in Dystrophin-deficient Muscle of Mice

Sandri, M., Podhorska‐Okołów, M., Géromel, V., Rizzi, C., Arslan, P., Franceschi, C., & Carraro, U. (1997) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199701000-00005 · Cited by 131 · see citing works

Stress-induced oxidative changes in brain.

Madrigal, J. L., García-Bueno, B., Caso, J., Perez-Nievas, B., & Leza, J. (2006) · CNS and Neurological Disorders - Drug Targets · doi:10.2174/187152706778559327 · Cited by 129 · see citing works

Oxygen, antioxidants and brain dysfunction

Choi, B. H. (1993) · Yonsei Medical Journal · doi:10.3349/ymj.1993.34.1.1 · Cited by 122 · see citing works

Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency

Zigmond, M. J., Cameron, J. L., Leak, R. K., Mirnics, K., Russell, V. A., Smeyne, R. J., & Smith, A. D. (2009) · Parkinsonism &amp; Related Disorders · doi:10.1016/s1353-8020(09)70778-3 · Cited by 121 · see citing works

Prolonged Cyclooxygenase-2 Induction in Neurons and Glia Following Traumatic Brain Injury in the Rat

Strauss, K. I., Barbe, M. F., Marshall, R. M., Raghupathi, R., Mehta, S. D., & Narayan, R. K. (2000) · Journal of Neurotrauma · doi:10.1089/089771500415436 · Cited by 120 · see citing works

Corticosteroid receptor-dependent modulation of calcium currents in rat hippocampal CA1 neurons

Karst, H., Wadman, W. J., & Joëls, M. (1994) · Brain Research · doi:10.1016/0006-8993(94)91069-3 · Cited by 119 · see citing works

Exercise protects against MPTP-induced neurotoxicity in mice

Gerecke, K. M., Jiao, Y., Pani, A. K., Pagala, V., & Smeyne, R. J. (2010) · Brain Research · doi:10.1016/j.brainres.2010.01.053 · Cited by 114 · see citing works

MPP + ‐induced COX‐2 activation and subsequent dopaminergic neurodegeneration

Wang, T., Pei, Z., Zhang, W., Liu, B., Langenbach, R. I., Lee, C., Wilson, B. C., Reece, J. M., Miller, D. S., & Hong, J. (2005) · The FASEB Journal · doi:10.1096/fj.04-2457fje · Cited by 113 · see citing works

Stress-induced Parkinson's disease: a working hypothesis

SMITH, A., Castro, S., & Zigmond, M. J. (2002) · Physiology & Behavior · doi:10.1016/s0031-9384(02)00939-3 · Cited by 110 · see citing works

Markers of protein oxidation by hydroxyl radical and reactive nitrogen species in tissues of aging rats

Leeuwenburgh, C., Hansen, P. A., Shaish, A., Holloszy, J. O., & Heinecke, J. W. (1998) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1998.274.2.r453 · Cited by 110 · see citing works

Macrophage migration inhibitory factor in the cerebrospinal fluid of patients with conventional and optic-spinal forms of multiple sclerosis and neuro-Behçet’s disease

Niino, M., Ogata, A., Kikuchi, S., Tashiro, K., & Nishihira, J. (2000) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(00)00397-x · Cited by 109 · see citing works

Down-regulation of neural corticosterone receptors by corticosterone and dexamethasone

Sapolsky, R. M., & McEwen, B. S. (1985) · Brain Research · doi:10.1016/0006-8993(85)90638-9 · Cited by 106 · see citing works

Inflammatory process as a determinant factor for the degeneration of substantia nigra dopaminergic neurons

Herrera, A. J., Tomás‐Camardiel, M., Venero, J. L., Cano, J., & Machado, A. (2004) · Journal of Neural Transmission · doi:10.1007/s00702-004-0121-3 · Cited by 103 · see citing works

Single bout of exercise eliminates the immobilization-induced oxidative stress in rat brain

Radak, Z. O., Sasvári, M., Nyakas, C. J., Kaneko, T., Tahara, S., Ohno, H., & Goto, S. (2001) · Neurochemistry International · doi:10.1016/s0197-0186(01)00003-1 · Cited by 97 · see citing works

Kinetics of glucocorticoid response to restraint stress and/or experimental influenza viral infection in two inbred strains of mice

Hermann, G. E., Tovar, C. A., Beck, F. M., & Sheridan, J. F. (1994) · Journal of Neuroimmunology · doi:10.1016/0165-5728(94)90177-5 · Cited by 92 · see citing works

Adrenal steroid influences on the survival of hippocampal neurons

McEwen, B. S., & Gould, E. A. (1990) · Biochemical Pharmacology · doi:10.1016/0006-2952(90)90079-z · Cited by 89 · see citing works

Inhibition of Glutamate Release via Recovery of ATP Levels Accounts for a Neuroprotective Effect of Aspirin in Rat Cortical Neurons Exposed to Oxygen-Glucose Deprivation

de Cristóbal, J., Cárdenas, A., Lizasoaín, I., Leza, J. C., Fernández-Tomé, P., Lorenzo, P. L., & Moro, M. Á. (2002) · Stroke · doi:10.1161/hs0102.101299 · Cited by 89 · see citing works

Axonal Damage Induced by Invading T Cells in Organotypic Central Nervous System Tissue in vitro: Involvement of Microglial Cells

Gimsa, U., Peter, S., Lehmann, K. R., Bechmann, I., & Nitsch, R. (2000) · Brain Pathology · doi:10.1111/j.1750-3639.2000.tb00268.x · Cited by 89 · see citing works

Activity-stress induces atrophy of apical dendrites of hippocampal pyramidal neurons in male rats

Lambert, K. G., Buckelew, S. K., Staffiso-Sandoz, G., Gaffga, S., Carpenter, W., Fisher, J. M., & Kinsley, C. H. (1998) · Physiology & Behavior · doi:10.1016/s0031-9384(98)00114-0 · Cited by 87 · see citing works

Additive Neuroprotective Effects of Creatine and a Cyclooxygenase 2 Inhibitor Against Dopamine Depletion in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Mouse Model of Parkinson's Disease

Klivènyi, P., Gardian, G., Calingasan, N. Y., Yang, L., & Beal, M. F. (2003) · Journal of Molecular Neuroscience · doi:10.1385/jmn:21:3:191 · Cited by 83 · see citing works

Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity

Culmsee, C., Bondada, S., & Mattson, M. P. (2001) · Molecular Brain Research · doi:10.1016/s0169-328x(01)00008-0 · Cited by 78 · see citing works

Effect of Resistance Training on Blood Oxidative Stress in Parkinson Disease

Bloomer, R. J., Schilling, B. K., Karlage, R. E., LeDoux, M. S., Pfeiffer, R. F., & Callegari, J. P. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31816f1550 · Cited by 77 · see citing works

Norepinephrine protects cortical neurons against microglial‐induced cell death

Madrigal, J. L. M., Feinstein, D. L., & Russo, C. D. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20481 · Cited by 77 · see citing works

Regular voluntary exercise cures stress-induced impairment of cognitive function and cell proliferation accompanied by increases in cerebral IGF-1 and GST activity in mice

Nakajima, S., Ohsawa, I., Ohta, S., Ohno, M., & Mikami, T. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.03.028 · Cited by 77 · see citing works

Increased oxidative stress brought on by pro-inflammatory cytokines in neurodegenerative processes and the protective role of nitrone-based free radical traps

Floyd, R. A., Hensley, K., Jaffery, F., Maidt, M. L., Robinson, K. A., Pye, Q. N., & Stewart, C. A. (1999) · Life Sciences · doi:10.1016/s0024-3205(99)00443-9 · Cited by 77 · see citing works

Generation of reactive oxygen species during the monoamine oxidase-catalyzed oxidation of the neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Zang, L., & Misra, H. P. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)85448-0 · Cited by 75 · see citing works

Impact of chronic intermittent challenges in stressor-susceptible and resilient strains of mice

Tannenbaum, B. M., & Anisman, H. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01487-7 · Cited by 71 · see citing works

Neuroprotective Effects of Nonsteroidal Anti-inflammatory Drugs on Neurodegenerative Diseases

Asanuma, M., Miyazaki, I., & Ogawa, N. (2004) · Current Pharmaceutical Design · doi:10.2174/1381612043453072 · Cited by 68 · see citing works

Effects of treadmill exercise on behavioral recovery and neural changes in the substantia nigra and striatum of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse

Smith, B. A., Goldberg, N. R. S., & Meshul, C. K. (2011) · Brain Research · doi:10.1016/j.brainres.2011.02.003 · Cited by 67 · see citing works

Glucocorticoids Stimulate Inflammatory 5‐Lipoxygenase Gene Expression and Protein Translocation in the Brain

Uz, T., Dwivedi, Y. K., Savani, P. D., Impagnatiello, F., Pandey, G., & Manev, H. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0730693.x · Cited by 67 · see citing works

Primary Degenerative Mild Cognitive Impairment: Study Population, Clinical, Brain Imaging and Biochemical Findings

Lautenschlager, N. T., Riemenschneider, M., Drzezga, A. E., & Kurz, A. (2001) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000051284 · Cited by 66 · see citing works

Relationship between cyclooxygenase‐2 and nitric oxide synthase‐2 in rat cortex after stress

Madrigal, J. L. M., García‐Bueno, B., Moro, M. Á., Lizasoaín, I., Lorenzo, P. L., & Leza, J. C. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02888.x · Cited by 64 · see citing works

Activity-Stress Increases Density of GFAP-Immunoreactive Astrocytes in the Rat Hippocampus

Lambert, K., Gerecke, K. M., Quadros, P., Doudera, E., Jasnow, A., & Kinsley, C. (2000) · Stress · doi:10.3109/10253890009001133 · Cited by 59 · see citing works

Effects of Physical Conditioning on Information-Processing Efficiency

Blomquist, K. B., & Danner, F. (1987) · Perceptual and Motor Skills · doi:10.2466/pms.1987.65.1.175 · Cited by 57 · see citing works

Brain-derived neurotrophic factor inhibits apoptosis and dopamine-induced free radical production in striatal neurons but does not prevent cell death

Petersén, Å., Larsen, K. E., Behr, G. G., Romero, N., Przedborski, S., Brundin, P., & Sulzer, D. L. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00580-9 · Cited by 56 · see citing works

Exercise does not protect against MPTP-induced neurotoxicity in BDNF happloinsufficent mice

Gerecke, K. M., Jiao, Y., Pagala, V., & Smeyne, R. J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043250 · Cited by 53 · see citing works

Restraint stress-induced elevations in plasma corticosterone and β-endorphin are not accompanied by alterations in immune function

Flores, C. M., Hernandez, M. C., Hargreaves, K., & Bayer, B. (1990) · Journal of Neuroimmunology · doi:10.1016/0165-5728(90)90015-f · Cited by 53 · see citing works

Pharmacological modulation of stress-induced behavioral changes in the light/dark exploration test in male C57BL/6J mice

Ihne, J. L., Fitzgerald, P. J., Hefner, K. R., & Holmes, A. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.08.045 · Cited by 52 · see citing works

The effect of exercise and oxidant–antioxidant intervention on the levels of neurotrophins and free radicals in spinal cord of rats

Siamilis, S., Jakus, J., Nyakas, C. J., Costa, A., Mihalik, B., Falus, A., & Radak, Z. O. (2008) · Spinal Cord · doi:10.1038/sc.2008.125 · Cited by 46 · see citing works

Hippocampal neuronal death induced by kainic acid and restraint stress is suppressed by exercise

Kim, B.-S., Kim, M.-Y., & Leem, Y. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.06.029 · Cited by 36 · see citing works

Long-term control by corticosteroids of the inward rectifier in rat CA1 pyramidal neurons, in vitro

Karst, H., Wadman, W. J., & Joëls, M. (1993) · Brain Research · doi:10.1016/0006-8993(93)91658-f · Cited by 35 · see citing works

Effect of repeated immobilization on serotonin metabolism in different rat brain areas and on serum corticosterone

Clement, H.-W., Kirsch, M., Hasse, C., Opper, C., Gemsa, D., & Wesemann, W. (1998) · Journal of Neural Transmission · doi:10.1007/s007020050119 · Cited by 31 · see citing works

Naproxen Reduces Excitotoxic Neurodegeneration in Vivo with an Extended Therapeutic Window

Silakova, J. M., Hewett, J. A., & Hewett, S. J. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.063867 · Cited by 29 · see citing works

Tenoxicam Exerts a Neuroprotective Action after Cerebral Ischemia in Rats

Galvão, R. I. M., Diógenes, J. P. L., Maia, G. C. L., Filho, E. A. S., Vasconcelos, S. M. M., de Menezes, D. B., Cunha, G. M. A., & Viana, G. S. D. B. (2005) · Neurochemical Research · doi:10.1007/s11064-004-9684-5 · Cited by 24 · see citing works

Exercise reverses chronic stress-induced Bax oligomer formation in the cerebral cortex

Haack, D., Luu, H. T., Cho, J., Chen, M. J., & Russo‐Neustadt, A. A. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.04.070 · Cited by 21 · see citing works

A quantitative study of the perikaryon and the basal dendritic tree in rat hippocampus (CA1) pyramids following different experimental procedures

Horner, C. H., O'Regan, M. E., & Arbuthnott, E. R. (1993) · Irish Journal of Medical Science (1971 -) · doi:10.1007/bf02957574 · Cited by 3 · see citing works

Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

Langston, J. W., Forno, L. S., Tetrud, J., Reeves, A. G., Kaplan, J. A., & Karluk, D. (1999) · Annals of Neurology · doi:10.1002/1531-8249(199910)46:4 · Cited by 1 · see citing works

Dietary Patterns and Depressive Symptoms over Time: Examining the Relationships with Socioeconomic Position, Health Behaviours and Cardiovascular Risk

Jacka, F. N., Cherbuin, N., Anstey, K. J., & Butterworth, P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087657 · Cited by 164 · see citing works

Microglia in neuronal plasticity: Influence of stress

Delpech, J.-C., Madore, C., Nadjar, A., Joffre, C., Wohleb, E. S., & Layé, S. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.12.034 · Cited by 157 · see citing works

Running from Stress: Neurobiological Mechanisms of Exercise-Induced Stress Resilience

Nowacka-Chmielewska, M. M., Grabowska, K., Grabowski, M., Meybohm, P., Burek, M., & Małecki, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113348 · Cited by 117 · see citing works

Modulation of synaptic plasticity by exercise

Bettio, L. E. B., Thacker, J. S., Hutton, C. P., & Christie, B. R. (2019) · International review of neurobiology · doi:10.1016/bs.irn.2019.07.002 · Cited by 82 · see citing works

Neuroendocrine, neuroinflammatory and pathological outcomes of chronic stress: A story of microglial remodeling

Picard, K., St‐Pierre, M., Vecchiarelli, H. A., Bordeleau, M., & Tremblay, M. (2021) · Neurochemistry International · doi:10.1016/j.neuint.2021.104987 · Cited by 77 · see citing works

Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice

Bergamini, G., Mechtersheimer, J., Azzinnari, D., Sigrist, H., Buerge, M., Dallmann, R., Freije, R., Kouraki, A., Opacka‐Juffry, J., Seifritz, E., et al. (2018) · Neurobiology of Stress · doi:10.1016/j.ynstr.2018.01.004 · Cited by 72 · see citing works

A Chronic fatigue syndrome model demonstrates mechanical allodynia and muscular hyperalgesia via spinal microglial activation

Yasui, M., Yoshimura, T., Takeuchi, S., Tokizane, K., Tsuda, M., Inoue, K., & Kiyama, H. (2014) · Glia · doi:10.1002/glia.22687 · Cited by 67 · see citing works

The benefits of staying active in old age: Physical activity counteracts the negative influence of PICALM, BIN1, and CLU risk alleles on episodic memory functioning.

Ferencz, B., Laukka, E. J., Welmer, A., Kalpouzos, G., Angleman, S. B., Keller, L., Graff, C., Lövdén, M., & Bäckman, L. (2014) · Psychology and Aging · doi:10.1037/a0035465 · Cited by 60 · see citing works

The neurogenic effects of an enriched environment and its protection against the behavioral consequences of chronic mild stress persistent after enrichment cessation in six-month-old female Balb/C mice

Vega‐Rivera, N. M., Ortíz‐López, L., Gómez‐Sánchez, A., Oikawa‐Sala, J., Estrada-Camarena, E. M., & Ramírez-Rodríguez, G. B. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.12.028 · Cited by 48 · see citing works

Moderate Treadmill Exercise Protects Synaptic Plasticity of the Dentate Gyrus and Related Signaling Cascade in a Rat Model of Alzheimer’s Disease

Dao, A. T., Zagaar, M. A., & Alkadhi, K. A. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8916-1 · Cited by 48 · see citing works

Microglia under psychosocial stressors along the aging trajectory: Consequences on neuronal circuits, behavior, and brain diseases

Tian, L., Hui, C. W., Bisht, K., Tan, Y., Sharma, K. P., Chen, S., Zhang, X., & Tremblay, M. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.01.007 · Cited by 47 · see citing works

Effects of green tea and physical exercise on memory impairments associated with aging

Flôres, M. F., Martins, A., Schimidt, H. L., Cibin, F. W. S., Izquierdo, I., Mello‐Carpes, P. B., & Carpes, F. P. (2014) · Neurochemistry International · doi:10.1016/j.neuint.2014.08.008 · Cited by 41 · see citing works

Ginsenoside Rb1 exerts antidepressant-like effects via suppression inflammation and activation of AKT pathway

Guo, Y., Xie, J., Zhang, L., Yang, L., Ma, J., Bai, Y., Ma, W., Wang, X., Yu, H., Zeng, Y.-Q., et al. (2020) · Neuroscience Letters · doi:10.1016/j.neulet.2020.135561 · Cited by 36 · see citing works

Physical exercise regulates microglia in health and disease

Strohm, A. O., & Majewska, A. K. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1420322 · Cited by 37 · see citing works

The effect of high-fat diet on seizure threshold in rats: Role of oxidative stress

Alzoubi, K. H., Hasan, Z. A., Khabour, O. F., Mayyas, F., Yacoub, O. N. A., Banihani, S. A., Azab, M. A., & Alrabadi, N. (2018) · Physiology & Behavior · doi:10.1016/j.physbeh.2018.08.011 · Cited by 33 · see citing works

Intense exercise can cause excessive apoptosis and synapse plasticity damage in rat hippocampus through Ca2+ overload and endoplasmic reticulum stress-induced apoptosis pathway

Ding, Y., Chang, C.-Q., Xie, L., Zhimin, C., & Hua, A. (2014) · Chinese Medical Journal · doi:10.1097/00029330-201409200-00014 · Cited by 30 · see citing works

Compounds from Ilex paraguariensis extracts have antioxidant effects in the brains of rats subjected to chronic immobilization stress

Colpo, A. Z. C., de Lima, M. E., Maya-López, M., da Rosa, H. S., Márquez-Curiel, C., Galván‐Arzate, S., Santamarı́a, A., & Folmer, V. (2017) · Applied Physiology Nutrition and Metabolism · doi:10.1139/apnm-2017-0267 · Cited by 24 · see citing works

Mechanisms underlying the beneficial effects of physical exercise on multiple sclerosis: focus on immune cells

Zong, B., Yu, F., Zhang, X., Zhao, W., Li, S., & Li, L. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1260663 · Cited by 23 · see citing works

Using sulcal and gyral measures of brain structure to investigate benefits of an active lifestyle

Lamont, A. J., Mortby, M. E., Anstey, K. J., Sachdev, P. S., & Cherbuin, N. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.01.008 · Cited by 22 · see citing works

Effects of doxepin on gene expressions of Bcl-2 family, TNF-α, MAP kinase 14, and Akt1 in the hippocampus of rats exposed to stress

Reisi, P., Eidelkhani, N., Rafiee, L., Kazemi, M., Radahmadi, M., & Alaei, H. (2017) · Research in Pharmaceutical Sciences · doi:10.4103/1735-5362.199042 · Cited by 12 · see citing works

Dapagliflozin mitigates cognitive deficits in a rat model of chronic restrained stress by addressing insulin resistance and mitochondrial dysfunction

Gamal, N., Bakly, W. M. S. E., Saad, S. S. T., El-Waseef, D. A. E.-D. A., El‐Shal, A. S., Morsy, W. E., & Magdy, Y. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04136-5 · Cited by 10 · see citing works

Stress

Sun, M., & Alkon, D. L. (2014) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000045 · Cited by 10 · see citing works

Exercise-driven restoration of the alcohol-damaged brain

West, R. K., Najjar, L. Z., & Leasure, J. L. (2019) · International review of neurobiology · doi:10.1016/bs.irn.2019.07.003 · Cited by 10 · see citing works

Therapeutic effects of exercise on depression: The role of microglia

Li, L., Ren, L., Ren, L., & Li, B. (2024) · Brain Research · doi:10.1016/j.brainres.2024.149279 · Cited by 7 · see citing works

From Stress to Substance Use Disorders: The Expanding Role of Microglia–Astrocyte Crosstalk in Neuroimmune and Glutamate Alterations in the Nucleus Accumbens

Cancela, L. M., Mongi‐Bragato, B., Avalos, M. P., & Bollati, F. A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms27010385 · Cited by 9 · see citing works

Interval aerobic training improves bioenergetics state and mitochondrial dynamics of different brain regions in restraint stressed rats

Khodagholi, F., Shahamati, S. Z., Chamgordani, M. M., Mousavi, M. A., Moslemi, M., Salehpour, M., Rafiei, S., & Foolad, F. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06177-4 · Cited by 6 · see citing works

Animal Models of Depression and Chronic Fatigue Syndrome

Singh, S., Vandana, Gill, H. K., & Bansal, P. (2017) · Springer eBooks · doi:10.1007/978-981-10-5981-0_11 · Cited by 3 · see citing works

Entrenamiento Aeróbico: Efecto Sobre el Estado Oxidativo Hepático. [Aerobic Training: Effect on Liver Oxidative Stress].

Matheus, N., Mendoza, C., Meléndez, C., Flores, C., Corro, A. C., Medina, I., & Báez, E. (2016) · RICYDE Revista Internacional de Ciencias del Deporte · doi:10.5232/ricyde2016.04506 · Cited by 1 · see citing works

Associations between dietary patterns and depression and anxiety in middle-aged adults: A large cross-sectional analysis among Iranian manufacturing employees

Roohafza, H., Feizi, A., Zakizadeh, E., Saraf‐Bank, S., Haghighatdoost, F., Fazelian, S., & Sarrafzadegan, N. (2019) · Advances in Human Biology · doi:10.4103/aihb.aihb_34_19 · Cited by 2 · see citing works

Loss of Collapsin Response Mediator Protein 4 Attenuates 6-Hydroxydopamine-Induced Impairments in a Mouse Model of Parkinson’s Disease

Li, W., Goshima, Y., & Ohshima, T. (2020) · Neurochemical Research · doi:10.1007/s11064-020-03086-z · Cited by 2 · see citing works

Exercise‐Induced Protection Against Aging and Neurodegenerative Diseases

Marques‐Aleixo, I., Alves, E. S., Moreira, P. I., Oliveira, P. J., Magalhães, J., & Ascensão, A. A. M. R. (2015) · Wiley eBooks · doi:10.1002/9781118840634.ch26 · Cited by 2 · see citing works

Beyond Stigma–Integrating Neurobiology, Genetics, and Awareness Integration Theory in Addiction Recovery

Blum, K., Gold, M., Jafari, N., Lewandrowski, K.-U., Sharafshah, A., Mohankumar, K., Lorio, M., Bowirrat, A., Pinhasov, A., Thanos, K., et al. (2026) · Psychology Research and Behavior Management · doi:10.2147/prbm.s561157 · Cited by 1 · see citing works

Current Understanding of Concussion: Treatment Perspectives

Gay, M. R., & Rosenthal, S. L. (2014) · Springer eBooks · doi:10.1007/978-1-4939-0295-8_21

High Fat Diet Affects The Dopamine Reward System: Importance Of Sex And Critical Developmental Periods

Carlin, J. L. (2014) · Scholarly Commons (University of Pennsylvania)

An attempt to enhance neurogenesis of mdx mice via aerobic exercise and myostatin inhibition

Ylikulju, T. (2013) · Jyväskylä University Digital Archive (University of Jyväskylä)

The Unexplored Relationship Between Diet & Mental Health: A Review

Khanna, P. (2016) · Journal of Medical Science And clinical Research · doi:10.18535/jmscr/v4i2.79

Exercise Improves High Fat-Induced Cognitive Impairment by Inhibiting Hippocampal Neuroinflammation via the Suppression of TLR4/MyD88/NF-κB Signaling Pathway

Li, H., Yu, Q., Ma, X., Liu, Q., & Zhai, Y. (2022) · Indian Journal of Pharmaceutical Sciences · doi:10.36468/pharmaceutical-sciences.spl.461

Adrenal steroid influences on the survival of hippocampal neurons

McEwen, B. S., & Gould, E. A. (1990) · Biochemical Pharmacology · doi:10.1016/0006-2952(90)90079-z · Cited by 89 · see citing works

Exercise reverses chronic stress-induced Bax oligomer formation in the cerebral cortex

Haack, D., Luu, H. T., Cho, J., Chen, M. J., & Russo‐Neustadt, A. A. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.04.070 · Cited by 21 · see citing works

The Effect of Exercise and Stress on Neurodegeneration in the Mouse Hippocampus

Kolobova, A., Fincher, D., & Patel, G. B. (2009)

Exercise ameliorates cognition impairment due to restraint stress-induced oxidative insult and reduced BDNF level

Kwon, D.-H., Kim, B.-S., Chang, H., Kim, Y.-I., Jo, S. A., & Leem, Y.-H. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.02.111 · Cited by 69 · see citing works

Effects of previous physical exercise to chronic stress on long‐term aversive memory and oxidative stress in amygdala and hippocampus of rats

dos Santos, T. M., Kolling, J., Siebert, C., Biasibetti, H., Bertó, C. G., Grün, L. K., Dalmaz, C., Barbé‐Tuana, F. M., & Wyse, Â. T. D. S. (2016) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2016.12.003 · Cited by 23 · see citing works