CoChat
Sign Up
Cited by 353Action Observation and SynchronizationMotor Control and AdaptationPrimate Behavior and Ecology

Observing others: multiple action representation in the frontal lobe.

Open access
Nelissen, Koen, Luppino, Giuseppe, Vanduffel, Wim, Rizzolatti, Giacomo, Orban, Guy A·2005·Science
DOI 10.1126/science.1115593
Open this paper in CoChat — free accountOpen PDF

Abstract

Observation of actions performed by others activates monkey ventral premotor cortex, where action meaning, but not object identity, is coded. In a functional MRI (fMRI) study, we investigated whether other monkey frontal areas respond to actions performed by others. Observation of a hand grasping objects activated four frontal areas: rostral F5 and areas 45B, 45A, and 46. Observation of an individual grasping an object also activated caudal F5, which indicates different degrees of action abstraction in F5. Observation of shapes activated area 45, but not premotor F5. Convergence of object and action information in area 45 may be important for full comprehension of actions.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1126/science.1115593

Cites

22 of 22 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • A new map of the ventral motor-prefrontal transitional region of the macaque cortex showed that area F5 consists of three subareas: F5c, F5p, and F5a.

    “Recently, a new map of the ventral motor-prefrontal transitional region of the macaque cortex has been proposed; it showed that area F5 consists of three subareas: F5c, F5p, and F5a [28],[29].”

    From Broca's Region: Novel Organizational Principles and Multiple Receptor Mapping (2010) · cites this paper as [29]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 49

  1. [1]1. V. Di Marzo, M. Bifulco, L. De Petrocellis, Nat. Rev. Drug Discov. 3, 771 (2004).
  2. [2]2. A. C. Howlett et al., Pharmacol. Rev. 54, 161 (2002).
  3. [3]3. L. De Petrocellis, M. G. Cascio, V. Di Marzo, Br. J. Pharmacol. 141, 765 (2004).
  4. [4]4. T. P. Dinh et al., Proc. Natl. Acad. Sci. U.S.A. 99, 10819 (2002).
  5. [5]5. T. F. Freund, I. Katona, D. Piomelli, Physiol. Rev. 83, 1017 (2003).
  6. [6]6. T. W. Klein et al., J. Leukoc. Biol. 74, 486 (2003).
  7. [7]7. S. D. Skaper et al., Proc. Natl. Acad. Sci. U.S.A. 93, 3984 (1996).
  8. [8]8. E. Nunez et al., Synapse 53, 208 (2004).
  9. [9]9. S. A. Golech et al., Brain Res. Mol. Brain Res. 132, 87 (2004).
  10. [10]10. C. Benito et al., J. Neurosci. 25, 2530 (2005).
  11. [11]11. C. Benito et al., J. Neurosci. 23, 11136 (2003).
  12. [12]12. G. Griffin, Q. Tao, M. E. Abood, J. Pharmacol. Exp. Ther. 292, 886 (2000).
  13. [13]13. S. M. Brown, J. Wager-Miller, K. Mackie, Biochim. Biophys. Acta 1576, 255 (2002).
  14. [15]15. I. Matias et al., Eur. J. Biochem. 269, 3771 (2002).
  15. [16]16. M. D. Van Sickle, Q. J. Pittman, K. A. Sharkey, unpublished observations. 17. A. V. Derbenev, T. C. Stuart, B. N. Smith, J. Physiol. 559, 923 (2004).
  16. [17]17. M. D. Van Sickle et al., Gastroenterology 121, 767 (2001).
  17. [19]19. L. De Petrocellis, T. Bisogno, J. B. Davis, R. G. Pertwee, V. Di Marzo, FEBS Lett. 483, 52 (2000).
  18. [20]20. D. Fegley et al., J. Pharmacol. Exp. Ther. 313, 352 (2005).
  19. [21]21. M. D. Van Sickle, J. S. Davison, K. A. Sharkey, unpublished observations. 23. G. Marsicano et al., Science 302, 84 (2003).
  20. [22]22. S. Gaetani, V. Cuomo, D. Piomelli, Trends Mol. Med. 9, 474 (2003).
  21. [23]23. J. P. Chhatwal, M. Davis, K. A. Maguschak, K. J. Ressler, Neuropsychopharmacology 30, 516 (2005).
  22. [24]24. E. Valjent et al., Proc. Natl. Acad. Sci. U.S.A. 102, 491 (2005).
  23. [25]25. M. Bouaboula et al., Eur. J. Biochem. 237, 704 (1996).
  24. [26]26. T. W. Klein et al., J. Leukoc. Biol. 74, 486 (2003).
  25. [27]27. B. F. Cravatt, A. H. Lichtman, Curr. Opin. Chem. Biol. 7, 469 (2003).
  26. [28]28. N. E. Buckley et al., Eur. J. Pharmacol. 396, 141 (2000).
  27. [31]31. G. Rizzolatti, L. Fogassi, V. Gallese, Nat. Rev. Neurosci. 2, 661 (2001).
  28. [32]32. M. Jeannerod, Int. J. Sport Exerc. Psychol. 2, 376 (2004).
  29. [33]33. R. Saxe, S. Carey, N. Kanwisher, Annu. Rev. Psychol. 55, 87 (2004).
  30. [34]34. V. Gallese, L. Fadiga, L. Fogassi, G. Rizzolatti, Brain 119, 593 (1996).
  31. [35]35. G. Rizzolatti, L. Fadiga, V. Gallese, L. Fogassi, Brain Res. Cogn. Brain Res. 3, 131 (1996).
  32. [37]37. W. Vanduffel et al., Neuron 32, 565 (2001).
  33. [38]38. K. Denys et al., J. Neurosci. 24, 2551 (2004).
  34. [39]39. M. Koyama et al., Neuron 41, 795 (2004).
  35. [40]40. G. Rizzolatti, L. Craighero, Annu. Rev. Neurosci. 27, 169 (2004).
  36. [42]42. M. Petrides, D. N. Pandya, Eur. J. Neurosci. 16, 291 (2002).
  37. [44]44. Z. Kourtzi, N. Kanwisher, J. Neurosci. 20, 3310 (2000).
  38. [45]45. E. Kohler et al., Science 297, 846 (2002).
  39. [46]46. M. Petrides, G. Cadoret, S. Mackey, Nature 435, 1235 (2005).
  40. [47]47. S. J. Blakemore, C. Frith, Neuropsychologia 43, 260 (2005).
  41. [48]48. A. Murata et al., J. Neurophysiol. 78, 2226 (1997).
  42. [49]49. G. Luppino, A. Murata, P. Govoni, M. Matelli, Exp. Brain Res. 128, 181 (1999).
  43. [50]50. M. Petrides, D. N. Pandya, J. Comp. Neurol. 228, 105 (1984).
  44. [51]51. H. Sakata, M. Taira, Curr. Opin. Neurobiol. 4, 847 (1994).
  45. [52]52. M. Jeannerod, M. A. Arbib, G. Rizzolatti, H. Sakata, Trends Neurosci. 18, 314 (1995).
  46. [53]53. J. D. Schall, A. Morel, D. J. King, J. Bullier, J. Neurosci. 15, 4464 (1995).
  47. [54]54. Y. Miyashita, Annu. Rev. Neurosci. 16, 245 (1993).
  48. [55]55. G. Rizzolatti, M. A. Arbib, Trends Neurosci. 21, 188 (1998).
  49. [56]56. A. M. Lieberman, Haskins Lab. Status Rep. Speech Res. 113, 1 (1993).

Cited by

Sorted by citations

Related

Authors
Nelissen, K., Luppino, G., Vanduffel, W., Rizzolatti, G., & Orban, G. A.
Affiliations
University of Parma (IT)
Corresponding author
Orban, Guy A
ORCID
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
2005-10-14
Volume
310
Issue
5746
Pages
332-336
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.1115593
OpenAlex
W2056658067
Semantic Scholar
bfd8873ef9bb44e9c2a80d7e2fb60b889786023e
Cited by
352
References
22
Citations by year
2026: 4 · 2025: 3 · 2024: 8 · 2023: 8 · 2022: 7 · 2021: 8 · 2020: 14 · 2019: 5 · 2018: 13 · 2017: 17 · 2016: 17 · 2015: 17 · 2014: 16 · 2013: 18 · 2012: 25
FWCI
38.81
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
  • Lirias (submittedVersion, other-oa)
Topics
  • Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
  • Social Sciences › Psychology › Social Psychology › Primate Behavior and Ecology
Keywords
action observation, ventral premotor cortex, frontal lobe, F5, area 46, hand grasping, object identity, action abstraction, action understanding, primate brain
MeSH terms
Animals, Frontal Lobe, Humans, Interpersonal Relations, Macaca mulatta, Magnetic Resonance Imaging, Male, Motion Perception, Motor Activity, Neurons, Videotape Recording

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review