Extending Healthy Life Span—From Yeast to Humans

Cited by (1,019)

Items 301–400 of 1,019

  1. Anti-aging pharmacology: Promises and pitfalls
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    Nicola Veronese, Yanping Li, JoAnn Elisabeth Manson, Walter Churchill Willett, Luigi Fontana, Frank B. Hu · 2016 · BMJ
  3. Fasting Therapy for Treating and Preventing Disease - Current State of Evidence
    Andreas Michalsen, Chenying Li · 2013 · Complementary Medicine Research
  4. Proteostasis and aging of stem cells
    David Vı́lchez, Milos Simic, Andrew G. Dillin · 2013 · Trends in Cell Biology
  5. FnCpf1: a novel and efficient genome editing tool for Saccharomyces cerevisiae
    Michał Świat, Sofia Dashko, Maxime den Ridder, Melanie Wijsman, John van der OOST, Jean-Marc G Daran, Pascale A. S. Daran-Lapujade · 2017 · Nucleic Acids Research
  6. Fasting enhances cold resistance in fish through stimulating lipid catabolism and autophagy
    Dongliang Lu, Qiang Ma, Jing Wang, Ling‐Yu Li, Si‐Lan Han, Samwel Mchele Limbu, Dongliang Li, Liqiao Chen, Mei‐Ling Zhang, Zhen‐Yu Du · 2019 · The Journal of Physiology
  7. Ketone bodies, stress response, and redox homeostasis
    Pedro Rojas‐Morales, José Pedraza‐Chaverrí, Edilia Tapia · 2019 · Redox Biology
  8. Antiaging diets: Separating fact from fiction
    Mitchell B. Lee, Cristal M. Hill, Alessandro Bitto, Matt R. Kaeberlein · 2021 · Science
  9. Intermittent fasting reduces neuroinflammation in intracerebral hemorrhage through the Sirt3/Nrf2/HO-1 pathway
    Shuhui Dai, Jialiang Wei, Hongchen Zhang, Peng Luo, Yuefan Yang, Xiaofan Jiang, Zhou Fei, Wenbin Liang, Jian‐Li Jiang, Xia Li · 2022 · Journal of Neuroinflammation
  10. Pathways linking the early environment to long-term health and lifespan
    Sarah K. Barnes, Susan Elizabeth Ozanne · 2010 · Progress in Biophysics and Molecular Biology
  11. Regulation of longevity and oxidative stress by nutritional interventions: Role of methionine restriction
    Inés Sánchez-Román, Gustavo Barja · 2013 · Experimental Gerontology
  12. Applications of mass spectrometry to metabolomics and metabonomics: Detection of biomarkers of aging and of age‐related diseases
    Robert J. Mishur, Shane L. Rea · 2011 · Mass Spectrometry Reviews
  13. Rhizoma Coptidis and Berberine as a Natural Drug to Combat Aging and Aging-Related Diseases via Anti-Oxidation and AMPK Activation
    Zhifang Xu, Wei Feng, Qian Shen, Nan‐Nan Yu, Kun Yu, Shenjun Wang, Zhigang Chen, Seiji Shioda, Yi Guo · 2017 · Aging and Disease
  14. Regulation of GH and GH Signaling by Nutrients
    Marina Caputo, Stella Pigni, Emanuela Agosti, Tommaso Daffara, Alice Ferrero, Nicoletta Filigheddu, Flavia Prodam · 2021 · Cells
  15. Expansion of Bone Marrow Adipose Tissue During Caloric Restriction Is Associated With Increased Circulating Glucocorticoids and Not With Hypoleptinemia
    William Peter Cawthorn, Erica L. Scheller, Sebastian Demian Parlee, Hoai An Pham, Brian S. Learman, Catherine Redshaw, Richard J. Sulston, Aaron A. Burr, Arun K. Das, Becky R. Simon et al. · 2015 · Endocrinology
  16. Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans
    Yue Zhang, Anne Lanjuin, Suvagata Roy Chowdhury, Meeta Mistry, Carlos G. Silva-García, Heather J. M. Weir, Chia-Lin Lee, Caroline C. Escoubas, Emina Tabakovic, William B. Mair · 2019 · eLife
  17. Genetic and epigenetic regulation of human aging and longevity
    Morris, Brian J., Willcox, Bradley J., Donlon, Timothy A. · 2019 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  18. Studying aging in Drosophila
    Ying He, Heinrich Jasper · 2014 · Methods
  19. Dietary restriction.; mitochondrial function and aging: From yeast to humans
    Ruetenik, Andrea, Barrientos, Antoni · 2015 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
  20. mTOR signaling for biological control and cancer
    Anya Alayev, Marina K. Holz · 2013 · Journal of Cellular Physiology
  21. Life span extension by targeting a link between metabolism and histone acetylation in Drosophila
    Shahaf Peleg, Christian Feller, Ignasi Forné, Evelyn Schiller, Daniel C. Sévin, Tamás Schauer, Catherine Regnard, Tobias Straub, Matthias Prestel, Caroline Klima et al. · 2016 · EMBO Reports
  22. Universal DNA methylation age across mammalian tissues
    A.T. Lu, Zhe Fei, Amin Haghani, Todd R. Robeck, Joseph Alan Zoller, Chengzhang Li, Robert Lowe, Qi Jiang Yan, Joshua Zhang, H. Vu et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  23. Mice as a Mammalian Model for Research on the Genetics of Aging
    Rong Yuan, Luanne L. Peters, Beverly J. Paigen · 2011 · ILAR Journal
  24. Macronutrients and caloric intake in health and longevity
    Samantha M. Solon‐Biet, Sarah Jayne Mitchell, Rafael de Cabo, David Raubenheimer, David George Le Couteur, Stephen James Simpson · 2015 · Journal of Endocrinology
  25. The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species
    Didac Carmona‐Gutiérrez, Andreas Zimmermann, Katharina Kainz, Federico Pietrocola, Guo Chen, Silvia Maglioni, Alfonso Schiavi, Jihoon Nah, Sara Mertel, Christine Brigitte Beuschel et al. · 2019 · Nature Communications
  26. Physiological responses to cold and starvation stresses in the liver of yellow drum (Nibea albiflora) revealed by LC-MS metabolomics
    Shuang Jiao, Miaomiao Nie, Hongbin Song, Dongdong Xu, Feng You · 2020 · The Science of The Total Environment
  27. Genome-environment interactions that modulate aging: powerful targets for drug discovery
    de Magalhães, João Pedro, Wuttke, Daniel, Wood, Shona H., Plank, Michael, Vora, Chintan · 2012 · Pharmacological Reviews
  28. Chronic Inflammation in the Context of Everyday Life: Dietary Changes as Mitigating Factors
    Denisa Marilena Margina, Anca Ungurianu, Carmen Nicoleta Purdel, Dimitris Tsoukalas, Evangelia Sarandi, Maria Thanasoula, Fotios Tekos, Robin Mesnage, Demetrios Kouretas, Aristidis Michael Tsatsakis · 2020 · International Journal of Environmental Research and Public Health
  29. Aging is not a disease: implications for intervention
    Suresh I. S. Rattan · 2014 · Aging and Disease
  30. Exploration of age-related mitochondrial dysfunction and the anti-aging effects of resveratrol in zebrafish retina
    Ning Wang, Zhiwen Luo, Ming Jin, Weiwei Sheng, Han-Tsing Wang, Xinyi Long, Yue Wu, Piaopiao Hu, Hong A. Xu, Xu Zhang · 2019 · Aging
  31. Calorie restriction slows age-related microbiota changes in an Alzheimer’s disease model in female mice
    Laura M. Cox, Marissa J. Schafer, Jiho Sohn, Julia Vincentini, Howard L. Weiner, Stephen D. Ginsberg, Martin J. Blaser · 2019 · Scientific Reports
  32. Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging
    Tang, Duozhuang, Tao, Si, Chen, Zhiyang, Koliesnik, Ievgen Oleksandrovich, Calmes, Philip Gerald, Hoerr, Verena, Han, Bing, Gebert, Nadja, Zörnig, Martin, Löffler, Bettina et al. · 2016 · Journal of Experimental Medicine
  33. Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming
    Chondronasiou, Dafni, Gill, Diljeet, Mosteiro, Lluc, Urdinguio, Rocio G., Berenguer‐Llergo, Antonio, Aguilera, Mònica, Durand, Sylvere, Aprahamian, Fanny, Nirmalathasan, Nitharsshini, Abad, Maria et al. · 2022 · Aging Cell
  34. Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence
    Choi, In Young, Lee, Changhan, Longo, Valter D. · 2017 · Molecular and Cellular Endocrinology
  35. β-hydroxybutyrate as an Anti-Aging Metabolite
    Lian Y. Wang, Peijie Chen, Weihua Xiao · 2021 · Nutrients
  36. Targeting Cardiac Stem Cell Senescence to Treat Cardiac Aging and Disease
    Eleonora Cianflone, Michele Torella, Flavia Biamonte, Antonella De Angelis, Konrad Urbanek, Francesco Saverio Costanzo, Marcello Rota, Georgina M. Ellison, Daniele Torella · 2020 · Cells
  37. Longevity and aging
    Kaeberlein, Matt · 2013 · F1000Prime Reports
  38. Adaptive Capacity to Bacterial Diet Modulates Aging in C. elegans
    Shanshan Pang, Sean P. Curran · 2014 · Cell Metabolism
  39. Natural compounds with anti-ageing activity
    Aikaterini Argyropoulou, Nektarios Aligiannis, Ioannis P. Trougakos, Alexios‐Léandros Skaltsounis · 2013 · Natural Product Reports
  40. Molecular aging of the brain, neuroplasticity, and vulnerability to depression and other brain-related disorders
    Etienne L. Sibille · 2013 · Dialogues in Clinical Neuroscience
  41. Heat shock factor 1 mediates the longevity conferred by inhibition of TOR and insulin/IGF‐1 signaling pathways in C. elegans
    Keunhee Seo, Eun Seok Choi, Dong-Yeop Lee, Dae‐Eun Jeong, Sung Key Jang, Seung‐Jae Lee · 2013 · Aging Cell
  42. Bacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway
    Verónica Donato, Facundo Rodríguez Ayala, Sebastián Cogliati, Carlos Bauman, Juan Gabriel Costa, Cecilia Leñini, Roberto Ricardo Grau · 2017 · Nature Communications
  43. EPRS is a critical mTORC1–S6K1 effector that influences adiposity in mice
    Arif, Abul, Terenzi, Fulvia, Potdar, Alka A., Jia, Jie, Sacks, Jessica, China, Arnab, Halawani, Dalia, Vasu, Kommireddy, Li, Xiaoxia, Brown, J. Mark et al. · 2017 · Nature
  44. Alternative Animal Models of Aging Research
    Susanne Holtze, Ekaterina A. Gorshkova, Stanton H. Braude, Alessandro Cellerino, Philip Dammann, Thomas B. Hildebrandt, Andreas Hoeflich, Steve Hoffmann, Philipp Koch, Eva Terzibasi Tozzini et al. · 2021 · Frontiers in Molecular Biosciences
  45. Hormesis, cell death and aging
    Isabelle Martins, Lorenzo Galluzzi, Guido Kroemer · 2011 · Aging
  46. A longer and healthier life with TOR down-regulation: genetics and drugs
    Ivana Bjedov, Linda Partridge · 2011 · Biochemical Society Transactions
  47. The Epidemiology of Longevity and Exceptional Survival
    Anne B. Newman, Joanne M. Murabito · 2013 · Epidemiologic Reviews
  48. Effects of short-term fasting on cancer treatment
    Stefanie de Groot, Hanno Pijl, Jacobus J. M. van der Hoeven, Judith R. Kroep · 2019 · Journal of Experimental & Clinical Cancer Research
  49. Drugs that modulate aging: the promising yet difficult path ahead
    Kennedy, Brian K., Pennypacker, Juniper K. · 2014 · Translational research
  50. Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy
    Nagalingam Ravi Sundaresan, Vinodkumar B. Pillai, Mahesh P. Gupta · 2011 · Journal of Molecular and Cellular Cardiology
  51. RETRACTED: Fisetin as a caloric restriction mimetic protects rat brain against aging induced oxidative stress, apoptosis and neurodegeneration
    Sandeep Singh, Abhishek Kumar Singh, Geetika Garg, Syed Ibrahim Rizvi · 2017 · Life Sciences · Retracted
  52. The Interplay Between Respiratory Supercomplexes and ROS in Aging
    Maria Luisa Genova, Giorgio Lenaz · 2015 · Antioxidants and Redox Signaling
  53. Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice
    Vladimir Nikolaevich Anisimov, Tatiana S. Piskunova, Irina G. Popovich, Mark A. Zabezhinski, Маргарита Леонидовна Тындык, Peter A. Egormin, M. N. Yurova, Svetlana V. Rosenfeld, Anna V. Semenchenko, Irina G. Kovalenko et al. · 2010 · Aging
  54. Yeast as a tool to identify anti-aging compounds
    Andreas Zimmermann, Sebastian J. Hofer, Tobias Pendl, Katharina Kainz, Frank Madeo, Didac Carmona‐Gutiérrez · 2018 · FEMS Yeast Research
  55. The Multifaceted Role of Nutrient Sensing and mTORC1 Signaling in Physiology and Aging
    Stephanie Fernandes, Constantinos Demetriades · 2021 · Frontiers in Aging
  56. The hyperfunction theory: An emerging paradigm for the biology of aging
    David Gems · 2022 · Ageing Research Reviews
  57. Mouse models of ageing and their relevance to disease
    Kõks, Sulev, Dogan, Soner, Tuna, Bilge Guvenc, González-Navarro, Herminia, Potter, Paul, Vandenbroucke, Roosmarijn E. · 2016 · Mechanisms of Ageing and Development
  58. Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice
    Christian Baumeier, Daniel Kaiser, Jörg Heeren, Ludger Scheja, Clara John, Christoph Weise, Murat Eravci, Merit Lagerpusch, Gunnar Schulze, Hans‐Georg Joost et al. · 2015 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  59. Molecular Mechanisms Determining Lifespan in Short- and Long-Lived Species
    Xiao Tian, Andrei Seluanov, Vera A. Gorbunova · 2017 · Trends in Endocrinology and Metabolism
  60. High carbohydrate–low protein consumption maximizes Drosophila lifespan
    Kimberley D. Bruce, Sany Hoxha, Gil B. Carvalho, Ryuichi Yamada, Horng‐Dar Wang, Paul Karayan, Shan He, Ted Brummel, Pankaj Kapahi, William W. Ja · 2013 · Experimental Gerontology
  61. A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration
    Gräff, Johannes, Kahn, Martin, Samiei, Alireza, Gao, Jun, Ota, Kristie T., Rei, Damien, Tsai, Li-Huei · 2013 · The Journal of Neuroscience
  62. Omics technologies and the study of human ageing
    Ana Maria Valdes, Daniel Glass, Tim D. Spector · 2013 · Nature Reviews Genetics
  63. Muscle-specific 4E-BP1 signaling activation improves metabolic parameters during aging and obesity
    Tsai, Shihyin, Sitzmann, Joanna M., Dastidar, Somasish G., Rodriguez, Ariana A., Vu, Stephanie L., McDonald, Circe E., Academia, Emmeline C., O’Leary, Monique N., Ashe, Travis D., La Spada, Albert R. et al. · 2015 · Journal of Clinical Investigation
  64. Lifespan, growth rate, and body size across latitude in marine Bivalvia, with implications for Phanerozoic evolution
    David K. Moss, Linda C. Ivany, Emily J. Judd, Patrick W. Cummings, Claire E. Bearden, Woo-Jun Kim, Emily G. Artruc, Jeremy R. Driscoll · 2016 · Proceedings of the Royal Society B Biological Sciences
  65. Nutrition and Athlete Immune Health: New Perspectives on an Old Paradigm
    Neil P. Walsh · 2019 · Sports Medicine
  66. The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging
    Seungjin Ryu, Sviatoslav Sidorov, Éric Ravussin, Maxim N. Artyomov, Akiko Iwasaki, Andrew Wang, Vishwa Deep Dixit · 2022 · Immunity
  67. Mapping the growth hormone–Stat5b–IGF-I transcriptional circuit
    Peter S. Rotwein · 2012 · Trends in Endocrinology and Metabolism
  68. Will calorie restriction work in humans?
    Edda Cava, Luigi Fontana · 2013 · Aging
  69. Cancer—Incidence, prevalence and mortality in the oldest-old. A comprehensive review
    Shantell C. Nolen, Marcella A. Evans, Avital Fischer, María M. Corrada, Claudia H. Kawas, Daniela Annenelie Bota · 2017 · Mechanisms of Ageing and Development
  70. mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder
    Marzia Perluigi A, Fabio Di Domenico, Eugenio Barone, David Allan Butterfield · 2021 · Free Radical Biology and Medicine
  71. Caloric restriction: Beneficial effects on brain aging and Alzheimer’s disease
    Van Cauwenberghe, Caroline, Vandendriessche, Charysse, Libert, Claude, Vandenbroucke, Roosmarijn E. · 2016 · Mammalian Genome
  72. Asynchronous, contagious and digital aging
    Rando, Thomas A., Wyss-Coray, Tony · 2021 · Nature Aging
  73. Regulation of longevity by FGF21: interaction between energy metabolism and stress responses
    Salminen, Antero, Kaarniranta, Kai, Kauppinen, Anu · 2017 · Ageing Research Reviews
  74. The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer's disease
    Tharusha Jayasena, Anne Poljak, George A. Smythe, Nady Braidy, Gerald W Münch, Perminder Singh Sachdev · 2013 · Ageing Research Reviews
  75. Association of Geroprotective Effects of Metformin and Risk of Open-Angle Glaucoma in Persons With Diabetes Mellitus
    Hsien‐Chang Lin, Joshua D. Stein, Bin Nan, David M. Childers, Paula Anne Newman-Casey, Debra A. Thompson, Julia E. Richards · 2015 · JAMA Ophthalmology
  76. Heritable Transmission of Stress Resistance by High Dietary Glucose in Caenorhabditis elegans
    Arnaud Tauffenberger, J. Alex Parker · 2014 · PLoS Genetics
  77. Molecular signatures of longevity: Insights from cross-species comparative studies
    Siming Ma, Vadim N. Gladyshev · 2017 · Seminars in Cell and Developmental Biology
  78. Mechanisms and rejuvenation strategies for aged hematopoietic stem cells
    Xia Li, Xiangjun Zeng, Yulin Xu, Binsheng Wang, Yanmin Zhao, Xiaoyu Lai, Pengxu Qian, He Huang · 2020 · Journal of Hematology & Oncology
  79. Caloric restriction and its mimetics
    Lee, Shin-Hae, Min, Kyung-Jin · 2013 · BMB Reports
  80. Body-composition changes in the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE)-2 study: a 2-y randomized controlled trial of calorie restriction in nonobese humans
    Das, Sai Krupa, Roberts, Susan B, Bhapkar, Manjushri V, Villareal, Dennis T, Fontana, Luigi, Martin, Corby K, Racette, Susan B, Fuss, Paul J, Kraus, William E, Wong, William W et al. · 2017 · The American Journal of Clinical Nutrition
  81. The road ahead for health and lifespan interventions
    Gonzalez-Freire, Marta, Diaz-Ruiz, Alberto, Hauser, David, Martinez-Romero, Jorge, Ferrucci, Luigi, Bernier, Michel, de Cabo, Rafael · 2020 · Ageing Research Reviews
  82. Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes
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  83. A Fasting-Responsive Signaling Pathway that Extends Life Span in C. elegans
    Masaharu Uno, Sakiko Honjoh, Mitsuhiro Matsuda, Haruka Hoshikawa, Saya Kishimoto, Tomohito Yamamoto, Miki Ebisuya, Takuya Yamamoto, Kunihiro Matsumoto, Eisuke Nishida · 2013 · Cell Reports
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  86. Dietary Curcumin Ameliorates Aging-Related Cerebrovascular Dysfunction through the AMPK/Uncoupling Protein 2 Pathway
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  95. Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age
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  99. The effect of resveratrol on lifespan depends on both gender and dietary nutrient composition in Drosophila melanogaster
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  100. Proteasome activation: An innovative promising approach for delaying aging and retarding age-related diseases
    Niki Chondrogianni, Konstantinos Voutetakis, Μαριάννα Καπετάνου, Vasiliki Delitsikou, Nikoletta Papaevgeniou, Marianthi Sakellari, Maria Lefaki, Konstantina Filippopoulou, Efstathios S. Gonos · 2014 · Ageing Research Reviews