Direct Gene Transfer into Mouse Muscle in Vivo
Wolff, Jon A., Malone, Robert W., Williams, Phillip, Chong, Wang, Acsadi, Gyula, Jani, Agnes, Felgner, Philip L.·1990·Science
Cited by (1,009)
Items 201–300 of 1,009
- Efficient gene transfer into myocardium by direct injection of adenovirus vectors.Raul J. Guzman, Patricia Lemarchand, Ronald G. Crystal, Stephen E. Epstein, Toren Finkel · 1993 · Circulation Research
- Poly(?-lactide-co-glycolide)-encapsulated plasmid DNA elicits systemic and mucosal antibody responses to encoded protein after oral administrationD Jones · 1997 · Vaccine
- Cytokine gene expression in epidermis with biological effects following injection of naked DNAUlrich R. Hengge, Edward F. Chan, Ruth A. Foster, Patricia Walker, Jonathan C. Vogel · 1995 · Nature Genetics
- Vaccine Technologies and Platforms for Infectious Diseases: Current Progress, Challenges, and OpportunitiesMajed Ghattas, Garima Dwivedi, Marc Lavertu, Mohamad‐Gabriel Alameh · 2021 · Vaccines
- Exposing the immunology of naked DNA vaccinesDrew M. Pardoll, Anne Marie Beckerleg · 1995 · Immunity
- Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccinesPollard, Charlotte, Rejman, Joanna, De Haes, Winni, Verrier, Bernard, Van Gulck, Ellen, Naessens, Thomas, De Smedt, Stefaan, Bogaert, Pieter, Grooten, Johan, Vanham, Guido et al. · 2013 · Molecular Therapy
- Lipid nanoparticles in the development of mRNA vaccines for COVID-19Barnabas Wilson, K.M. Geetha · 2022 · Journal of Drug Delivery Science and Technology
- mRNA vaccines in disease prevention and treatmentGang Zhang, Tianyu Tang, Yinfeng Chen, Xing Huang, Tingbo Liang · 2023 · Signal Transduction and Targeted Therapy
- Recent Advances in Lipid Nanoparticles and Their Safety Concerns for mRNA DeliveryJialiang Wang, Yaopeng Ding, K. Chul Chong, Meng Cui, Zeyu Cao, Chenjue Tang, Zhen Tian, Yuping Hu, Yu Zhao, Shaoyi Jiang · 2024 · Vaccines
- Gene Expression Following Direct Injection of DNA into LiverM. Anne Hickman, Robert W. Malone, Karin Lehmann‐Bruinsma, Tracey R. Sih, Daren L. Knoell, Francis C. Szoka, Rosemary L. Walzem, Don M. Carlson, Jerry Sherman Powell · 1994 · Human Gene Therapy
- Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune inductionJ.S. Boyle, J. L. Brady, Andrew M. Lew · 1998 · Nature
- Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteersThong P. Le, Kevin Coonan, Richard C. Hedstrom, Yupin Charoenvit, Martha Sedegah, Judith E. Epstein, Sanjai Kumar, Ruobing Wang, Denise L. Doolan, Jason D. Maguire et al. · 2000 · Vaccine
- Regulatable gene expression systems for gene therapy applications: progress and future challengesGoverdhana, S., Puntel, M., Xiong, W., Zirger, J.M., Barcia, C., Curtin, J.F., Soffer, E.B., Mondkar, S., King, G.D., Hu, J. et al. · 2005 · Molecular Therapy
- Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors.Brent A. French, Wojciech M. Mazur, Robert S. Geske, Roberto Bolli · 1994 · Circulation
- Materials for protein delivery in tissue engineeringSamuel P. Baldwin, W. Mark Saltzman · 1998 · Advanced Drug Delivery Reviews
- Advancements in DNA vaccine vectors, non-mechanical delivery methods, and molecular adjuvants to increase immunogenicityJohn J. Suschak, James A. Williams, Connie S. Schmaljohn · 2017 · Human Vaccines & Immunotherapeutics
- Cancer mRNA vaccines: clinical advances and future opportunitiesElias Joseph Sayour, David Boczkowski, Duane A. Mitchell, Smita K. Nair · 2024 · Nature Reviews Clinical Oncology
- Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipidsColin William Pouton, Paul Lucas, Beverley J Thomas, Aima N. Uduehi, David Milroy, Stephen H. Moss · 1998 · Journal of Controlled Release
- Chitosans for delivery of nucleic acidsMichael D. Buschmann, Abderrazzak Merzouki, Marc Lavertu, Marc Thibault, Myriam Jean, Vincent Darras · 2013 · Advanced Drug Delivery Reviews
- Adenovirus vector-mediated in vivo gene transfer into adult murine retina.Jean Bennett, James M. Wilson, Daxi Sun, Brian John Forbes, A. Maguire · 1994 · PubMed
- Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA–liposome complexesGary J. Nabel, David Gordon, D. Keith Bishop, Brian J. Nickoloff, Zhiyong Yang, Atsushi Aruga, Mark J. Cameron, Elizabeth G. Nabel, Alfred E. Chang · 1996 · Proceedings of the National Academy of Sciences
- Mucosal immunity and tolerance: relevance to vaccine developmentCecil C. Czerkinsky, Fabienne Anjueie, Jerry R. McGhee, Annie Geoige‐Chundy, Jan R. Holmgren, Marie-Paule Kiény, Kohlaro Fujiyashi, Jiri F. Mestecky, Valérie Pierrefite‐Carle, Carok Rusk et al. · 1999 · Immunological Reviews
- Immunologic Basis of Vaccine VectorsMargaret A. Liu · 2010 · Immunity
- Optimisation of electrotransfer of plasmid into skeletal muscle by pretreatment with hyaluronidase – increased expression with reduced muscle damageJill M. McMahon, Emanuela Signori, KE Wells, Vito Michele Fazio, Dominic J. Wells · 2001 · Gene Therapy
- Improved Cationic Lipid Formulations for In Vivo Gene TherapyPhilip Louis Felgner, Ya-Li Tsai, Loretta Sukhu, Carl J. Wheeler, Marston Manthorpe, John Marshall, Seng H. Cheng · 1995 · Annals of the New York Academy of Sciences
- Mechanism of action of mRNA-based vaccinesIavarone, Carlo, O’hagan, Derek T., Yu, Dong, Delahaye, Nicolas F., Ulmer, Jeffrey B. · 2017 · Expert Review of Vaccines
- Enhancing immune responses using suicidal DNA vaccinesBerglund, Peter, Smerdou, Cristian, Fleeton, Marina N., Tubulekas, loannis, Liljeström, Peter · 1998 · Nature Biotechnology
- New delivery system for plasmid DNA in vivo using atelocollagen as a carrier material: the MinipelletTakahiro Ochiya, Yasushi Takahama, Shunji Nagahara, Yoshihiro Sumita, Akihiko Hisada, Hiroshi Itoh, Yutaka Nagai, Masaaki Terada · 1999 · Nature Medicine
- Cytokine enhancement of DNA immunization leads to effective treatment of established pulmonary metastasesKari R. Irvine, J B Rao, Steven A. Rosenberg, Nicholas P. Restifo · 1996 · The Journal of Immunology
- Improvement of hepatitis B virus DNA vaccines by plasmids coexpressing hepatitis B surface antigen and interleukin-2Yen‐Hung Chow, Wei-Lun Huang, W K, Yi-Wei Chu, Mi‐Hua Tao · 1997 · Journal of Virology
- Protective CD4+and CD8+T Cells against Influenza Virus Induced by Vaccination with Nucleoprotein DNAJeffrey B. Ulmer, Tong‐Ming Fu, R. Randall Deck, Arthur Friedman, Liming Guan, Corrille M. DeWitt, Xu Liu, Su Wang, Margaret A. Liu, John Donnelly et al. · 1998 · Journal of Virology
- In Vivo Electroporation for Gene TherapyLoreé C. Heller, Richard F. Heller · 2006 · Human Gene Therapy
- Intradermal Vaccinations With RNA Coding for TAA Generate CD8+ and CD4+ Immune Responses and Induce Clinical Benefit in Vaccinated PatientsRittig, Susanne M, Haentschel, Maik, Weimer, Katrin J, Heine, Annkristin, Muller, Martin R, Brugger, Wolfram, Horger, Marius S, Maksimovic, Olga, Stenzl, Arnulf, Hoerr, Ingmar et al. · 2011 · Molecular Therapy
- mRNA transcript therapyWeissman, Drew · 2015 · Expert Review of Vaccines
- Medical applications of electroporationS. B. Dev, Dietmar Rabussay, Georg Widera, G Hofmann · 2000 · IEEE Transactions on Plasma Science
- Development of antibody-siRNA conjugate targeted to cardiac and skeletal musclesTsukasa Sugo, Michiko Terada, Tatsuo Oikawa, Kenichi Miyata, Satoshi Nishimura, Eriya Kenjo, Mari Ogasawara-Shimizu, Yukimasa Makita, Sachiko Imaichi, Shumpei Murata et al. · 2016 · Journal of Controlled Release
- A novel, disruptive vaccination technology: Self-adjuvanted RNActive ® vaccinesKallen, Karl-Josef, Heidenreich, Regina, Schnee, Margit, Petsch, Benjamin, Schlake, Thomas, Thess, Andreas, Baumhof, Patrick, Scheel, Birgit, Koch, Sven D, Fotin-Mleczek, Mariola · 2013 · Human Vaccines & Immunotherapeutics
- Polyvinyl Derivatives as Novel Interactive Polymers for Controlled Gene Delivery to MuscleRussell J. Mumper, John G. Duguid, Khursheed Anwer, Melisa K. Barren, Hiroaki Nitta, Alain P. Rolland · 1996 · Pharmaceutical Research
- Advances in combating fungal diseases: vaccines on the thresholdJim E. Cutler, George S. Deepe, Bruce S. Klein · 2006 · Nature Reviews Microbiology
- Industrial scale production of plasmid DNA for vaccine and gene therapy: plasmid design, production, and purificationKristala L. J. Prather, Sangeetha L. Sagar, Jason C. Murphy, Michel M. Chartrain · 2003 · Enzyme and Microbial Technology
- Lipid nanoparticles (LNPs) for in vivo RNA delivery and their breakthrough technology for future applicationsMichaela Jeong, Yeji Lee, Jeongeun Park, Hyein Jung, Hyukjin Lee · 2023 · Advanced Drug Delivery Reviews
- Specific Immune Induction Following DNA-Based Immunization Through In Vivo Transfection and Activation of Macrophages/Antigen-Presenting CellsMichael A. Chattergoon, Tara M. Robinson, Jean Boyer, David B. Weiner · 1998 · The Journal of Immunology
- RNA-Based Vaccines in Cancer ImmunotherapyMegan Ann McNamara, Smita K. Nair, Eda K. Holl · 2015 · Journal of Immunology Research
- Biological features of genetic immunizationMichael A. Barry · 1997 · Vaccine
- Invited review: Myoblast transfer: A possible therapy for inherited myopathies?Terence A. Partridge · 1991 · Muscle & Nerve
- CD8 positive T cells influence antigen-specific immune responses through the expression of chemokines.Jong J. Kim, Liesl K. Nottingham, Jeong‐Im Sin, Anthony Tsai, Lake Daniel Morrison, J Oh, Kesen Dang, Y Hu, Ken Kazahaya, M Bennett et al. · 1998 · Journal of Clinical Investigation
- Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genesJong J. Kirn, Mark L. Bagarazzi, Neil N. Trivedi, Yin Hu, Ken Kazahaya, Darren M. Wilson, Richard B. Ciccarelli, Michael A. Chattergoon, Kesan Dang, Sundarasamy Mahalingam et al. · 1997 · Nature Biotechnology
- Ras is involved in nerve-activity-dependent regulation of muscle genesMarta Murgia, Antonio L. Serrano, Elisa Calabria, Giorgia Pallafacchina, Terje Lømo, Stefano Schiaffino · 2000 · Nature Cell Biology
- Paving the Road for RNA TherapeuticsNiels Dammes, Dan Peer · 2020 · Trends in Pharmacological Sciences
- Gene therapeuticsPhilip Louis Felgner, Gary H. Rhodes · 1991 · Nature
- Formulation and Delivery Technologies for mRNA VaccinesChunxi Zeng, Chengxiang Zhang, Patrick G. Walker, Yizhou Dong · 2020 · Current topics in microbiology and immunology
- Production of recombinant subunit vaccines: protein immunogens, live delivery systems and nucleic acid vaccinesSissela Liljeqvist, Stefan Ståhl · 1999 · Journal of Biotechnology
- Progress and prospects of mRNA-based drugs in pre-clinical and clinical applicationsYingying Shi, Meixing Shi, Yì Wáng, Jian You · 2024 · Signal Transduction and Targeted Therapy
- A combination of poloxamers increases gene expression of plasmid DNA in skeletal musclePierre Lemieux, Nadia Guérin, G Paradis, Raphaël Proulx, L. G. Chistyakova, Alexander V. Kabanov, Valery Yu. Alakhov · 2000 · Gene Therapy
- DNA vaccines: roles against diseasesKishwar Hayat Khan · 2013 · GERMS
- Non-viral COVID-19 vaccine delivery systemsKyung Soo Park, Xiaoqi Sun, Marisa E. Aikins, James Jaehyun Moon · 2020 · Advanced Drug Delivery Reviews
- Advances in Gene Delivery SystemsKamimura, Kenya, Suda, Takeshi, Zhang, Guisheng, Liu, Dexi · 2011 · Pharmaceutical Medicine
- Appraisal for the Potential of Viral and Nonviral Vectors in Gene Therapy: A ReviewMuhammad Hammad Butt, Muhammad Zaman, Abrar Ahmad, Rahima Khan, Tauqeer Hussain Mallhi, Mohammad Mehedi Hasan, Yusra Habib Khan, Sara Hafeez, Ehab El Sayed Massoud, Md. Habibur Rahman et al. · 2022 · Genes
- Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouseShaomin Zou, Patrick Erbacher, Jean-Serge Rémy, Jean‐Paul Behr · 2000 · The Journal of Gene Medicine
- Emergence of synthetic mRNA: In vitro synthesis of mRNA and its applications in regenerative medicineKwon, Hyokyoung, Kim, Minjeong, Seo, Yunmi, Moon, Yae Seul, Lee, Hwa Jeong, Lee, Kyuri, Lee, Hyukjin · 2018 · Biomaterials
- Extracellular Glycosaminoglycans Modify Cellular Trafficking of Lipoplexes and PolyplexesMarika Ruponen, Seppo Rönkkö, Paavo Honkakoski, Jukka Pelkonen, Markku Tammi, Arto O. Urtti · 2001 · Journal of Biological Chemistry
- Cancer Gene Therapy Using Plasmid DNA: Pharmacokinetic Study of DNA Following Injection in MiceDenise Lew, Suezanne E. Parker, T Latimer, A. M. Abai, Ann Kuwahara-Rundell, Soeun Grace Doh, Zhiyong Yang, Drake LaFace, Stanislaw H. Gromkowski, Gary J. Nabel et al. · 1995 · Human Gene Therapy
- Genetic Immunization Against the Human Thyrotropin Receptor Causes Thyroiditis and Allows Production of Monoclonal Antibodies Recognizing the Native ReceptorSabine Costagliola, Patrice Rodien, M -C Many, Marian Elizabeth Ludgate, Gilbert Vassart · 1998 · The Journal of Immunology
- How mRNA therapeutics are entering the monoclonal antibody fieldVan Hoecke, Lien, Roose, Kenny · 2019 · Journal of Translational Medicine
- Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependentProbst, J, Weide, B, Scheel, B, Pichler, B J, Hoerr, I, Rammensee, H-G, Pascolo, S · 2007 · Gene Therapy
- Combined DNA Immunization with the Glycoprotein Gene of Viral Hemorrhagic Septicemia Virus and Infectious Hematopoietic Necrosis Virus Induces Double-Specific Protective Immunity and Nonspecific Response in Rainbow TroutPierre Boudinot, M. Mar Blanco, Pierre de Kinkelin, Abdenour Benmansour · 1998 · Virology
- Pharmaceutical Approach to Somatic Gene TherapyFred David Ledley · 1996 · Pharmaceutical Research
- Polymer genomics: An insight into pharmacology and toxicology of nanomedicines☆Alexander V. Kabanov · 2006 · Advanced Drug Delivery Reviews
- Expression of naked plasmids by cultured myotubes and entry of plasmids into T tubules and caveolae of mammalian skeletal muscleJon A. Wolff, Martin E. Dowty, Shoushu Jiao, Gabriella Repetto, Randi K. Berg, James J. Ludtke, Phillip Williams, David B. Slautterback · 1992 · Journal of Cell Science
- Effect of Plasmid DNA Vaccine Design and In Vivo Electroporation on the Resulting Vaccine-Specific Immune Responses in Rhesus MacaquesAmara Luckay, Maninder K. Sidhu, Rune Kjeken, Shakuntala Megati, Siew-Yen Chong, Vidia Roopchand, Dorys Garcia-Hand, Rashed Abdullah, Ralph Peter Braun, David C. Montefiori et al. · 2007 · Journal of Virology
- Magnetic nanoparticles as targeted delivery systems in oncologySara Prijic, Gregor Serša · 2011 · Radiology and Oncology
- Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene deliveryChristopher L. Grigsby, Kam W. Leong · 2009 · Journal of The Royal Society Interface
- A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infectionKose, Nurgun, Fox, Julie M., Sapparapu, Gopal, Bombardi, Robin, Tennekoon, Rashika N., de Silva, A. Dharshan, Elbashir, Sayda M., Theisen, Matthew A., Humphris-Narayanan, Elisabeth, Ciaramella, Giuseppe et al. · 2019 · Science Immunology
- DNA Vaccines: Developing New Strategies against CancerDaniela Piergili Fioretti, Sandra Iurescia, Vito Michele Fazio, Monica Rinaldi · 2010 · BioMed Research International
- Gene Transfer by Adeno-Associated Virus Vectors into the Central Nervous SystemXiao Xiao, Juan Li, Thomas J. McCown, R. Jude Samulski · 1997 · Experimental Neurology
- Expression of naked DNA in human, pig, and mouse skin.Ulrich R. Hengge, Patricia S. Walker, Jonathan C. Vogel · 1996 · Journal of Clinical Investigation
- Formation of stable cationic lipid/DNA complexes for gene transfer.Hans E. J. Hofland, L.B. Shephard, Seán M. Sullivan · 1996 · Proceedings of the National Academy of Sciences
- Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeysDan H. Barouch, Abie Craiu, Marcelo J. Kuroda, Jörn E. Schmitz, Xin Xiao Zheng, Sampa Santra, Julie D. Frost, Georgia R. Krivulka, Michelle A. Lifton, Carroll L. Crabbs et al. · 2000 · Proceedings of the National Academy of Sciences
- Possible orthopaedic applications of gene therapy.Christopher H. Evans, Paul D. Robbins · 1995 · Journal of Bone and Joint Surgery
- Toll‐like receptor‐dependent activation of several human blood cell types by protamine‐condensed mRNABirgit Scheel, Regina Teufel, Jochen Probst, Jean‐Philippe Carralot, Jens Geginat, Markus Philipp Radsak, David Jarrossay, Hermann Wagner, Günther Jung, Hans‐Georg Rammensee et al. · 2005 · European Journal of Immunology
- Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2.Peter R. Strack, Michelle West Frey, Carmelo J. Rizzo, Beverly C. Cordova, Henry J. George, R Meade, S. P. HO, J Corman, R.J. Tritch, Bruce D. Korant · 1996 · Proceedings of the National Academy of Sciences
- Human Clinical Trials of Plasmid DNA VaccinesMargaret A. Liu, Jeffrey B. Ulmer · 2005 · Advances in genetics
- Immunization for Ebola virus infectionLing Xu, Anthony Sanchez, Zhiyong Yang, Sherif R. Zaki, Elizabeth G. Nabel, Stuart T. Nichol, Gary J. Nabel · 1998 · Nature Medicine
- Antiviral developmentsA.Paul Fiddian · 2000 · Reviews in Medical Virology
- Application of membrane-active peptides for nonviral gene deliveryErnst Wagner · 1999 · Advanced Drug Delivery Reviews
- A Facile Nonviral Method for Delivering Genes and siRNAs to Skeletal Muscle of Mammalian LimbsJames E. Hagstrom, Julia Hegge, Guofeng Zhang, Mark Noble, Vladimir G. Budker, David L. Lewis, Hans Herweijer, Jon A. Wolff · 2004 · Molecular Therapy
- Electroporation-Mediated Gene DeliveryJennifer L. Young, David A. Dean · 2014 · Advances in genetics
- Direct Intramuscular Injection of Plasmid DNA Encoding Angiopoietin-1 but not Angiopoietin-2 Augments Revascularization in the Rabbit Ischemic HindlimbKou‐Gi Shyu, Orit Manor, Meredith Magner, George D. Yancopoulos, Jeffrey M. Isner · 1998 · Circulation
- Non-viral vectors in cancer gene therapy: principles and progressAndreas G. Schätzlein · 2001 · Anti-Cancer Drugs
- Coping with the inevitable: how cells repair a torn surface membranePaul L. McNeil, Mark Terasaki · 2001 · Nature Cell Biology
- Nonviral Gene Delivery to the Rat Kidney with PolyethylenimineAlessandra Boletta, Ariela Benigni, Jens Lutz, Giuseppe Remuzzi, Marco R. Soria, Lucía Monaco · 1997 · Human Gene Therapy
- Current and future strategies for the treatment of malignant brain tumorsMaria Graciela Castro, Rachel L. Cowen, Ian Williamson, Anne David, Maximiliano Javier Jimenez-Dalmaroni, Xueer Yuan, A Bigliari, Judith C. Williams, Jinwei Hu, Pedro Ricardo Lowenstein · 2003 · Pharmacology & Therapeutics
- Linear DNAs Concatemerize in Vivo and Result in Sustained Transgene Expression in Mouse LiverZhi-Ying Chen, Stephen R. Yant, Cheng-Yi He, Leonard A. Meuse, Shiliang Shen, Mark A. Kay · 2001 · Molecular Therapy
- RNA: The new revolution in nucleic acid vaccinesAndrew J. Geall, Christian W. Mandl, Jeffrey B. Ulmer · 2013 · Seminars in Immunology
- Non-viral gene delivery in skeletal muscle: a protein factoryQ L Lu, George Bou–Gharios, Terence A. Partridge · 2003 · Gene Therapy
- In vitro and in vivo transfection of plasmid DNA in the Dunning prostate tumor R3327-AT1 is enhanced by focused ultrasoundPeter Ernst Huber, Petra H. Pfisterer · 2000 · Gene Therapy
- DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infectionM Yokoyama, J Zhang, J. Lindsay Whitton · 1995 · Journal of Virology
- Long-term, high level in vivo gene expression after electric pulse-mediated gene transfer into skeletal muscleLluis M. Mir, Michel Francis Bureau, Ravi Rangara, Bertrand Schwartz, Daniel Scherman · 1998 · Comptes Rendus de l Académie des Sciences - Series III - Sciences de la Vie
- RNA-based vaccinesJeffrey B. Ulmer, Peter W. Mason, Andrew J. Geall, Christian W. Mandl · 2012 · Vaccine
- Nucleic acid drugs: recent progress and future perspectivesXiaoyi Sun, Sarra Setrerrahmane, Chencheng Li, Jialiang Hu, Hanmei Xu · 2024 · Signal Transduction and Targeted Therapy