The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Light Pulses that Shift Rhythms Induce Gene Expressions in the Suprachiasmatic Nucleus
Abstract
Lighting cycles synchronize (entrain) mammalian circadian rhythms by altering activity of cells in the suprachiasmatic nucleus (SCN) of the hypothalamus, a circadian pacemaker. Exposure of hamsters and rats to light pulses at those phases of the circadian rhythm during which light can shift the rhythm caused increased immunoreactivity for the product of the immediate-early gene c- fos in cells in the region of the SCN that receives retinal fibers. Light pulses also increased messenger RNA for the Fos protein and for the immediate-early protein NGFI-A in the rat SCN. Similar increases in mRNA for NGFI-A were seen in the SCN of hamsters. Thus cells in this portion of the SCN undergo alterations in gene expression in response to retinal illumination, but only at times in the circadian cycle when light is capable of influencing entrainment.
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Expression of c- fos Protein in Brain: Metabolic Mapping at the Cellular Level
Sagar, S. M., Sharp, F. R., & Curran, T. (1988) · Science · doi:10.1126/science.3131879 · Cited by 1,925
Stimulus-transcription coupling in neurons: role of cellular immediate-early genes
Morgan, J. I., & Curran, T. (1989) · Trends in Neurosciences · doi:10.1016/0166-2236(89)90096-9 · Cited by 969
Circadian rhythm of firing rate recorded from single cells in the rat suprachiasmatic brain slice
Green, D. J., & Gillette, R. (1982) · Brain Research · doi:10.1016/0006-8993(82)90361-4 · Cited by 503
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Shigeyoshi, Y., Taguchi, K., Yamamoto, S., Takekida, S., Yan, L., Tei, H., Moriya, T., Shibata, S., Loros, J. J., Dunlap, J. C., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80494-8 · Cited by 891
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Robertson, G. S., Pfaus, J. G., Atkinson, L. J., Matsumura, H., Phillips, A. G., & Fibiger, H. C. (1991) · Brain Research · doi:10.1016/0006-8993(91)91477-i · Cited by 169
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Metadata
- Authors
- Rusak, B., Robertson, H. A., Wisden, W., & Hunt, S. P.
- Venue
- Science
- Published
- 1990-06-08
- Volume
- 248
- Issue
- 4960
- Pages
- 1237-1240
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1975146102
- Cited by
- 548
- References
- 3
- FWCI
- 28.47
- Type
- journal article
- Language
- en
- Open access
- closed
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