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Partial-thickness burn wounds healing by topical treatment: A randomized controlled comparison between silver sulfadiazine and centiderm

Saeidinia, A., Keihanian, F., Lashkari, A. P., Lahiji, H. G., Mobayyen, M., Heidarzade, A., & Golchai, J. (2017) · Medicine · doi:10.1097/md.0000000000006168 · Cited by 70 · see citing works

Polyurethane-biomacromolecule combined foam dressing containing asiaticoside: fabrication, characterization and clinical efficacy for traumatic dermal wound treatment

Namviriyachote, N., Muangman, P., Chinaroonchai, K., Chuntrasakul, C., & Ritthidej, G. C. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.10.166 · Cited by 68 · see citing works

Asiaticoside Induces Type I Collagen Synthesis and Osteogenic Differentiation in Human Periodontal Ligament Cells

Nowwarote, N., Osathanon, T., Jitjaturunt, P., Manopattanasoontorn, S., & Pavasant, P. (2012) · Phytotherapy Research · doi:10.1002/ptr.4742 · Cited by 50 · see citing works

Establishing the Pharmaceutical Quality of Chinese Herbal Medicine: A Provisional BCS Classification

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Ethnobotany, Phytochemistry and Pharmacological Features of Centella asiatica: A Comprehensive Review

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An optimization approach of dynamic maceration of Centella asiatica to obtain the highest content of four centelloids by response surface methodology

Monton, C., Settharaksa, S., Luprasong, C., & Songsak, T. (2019) · Revista Brasileira de Farmacognosia · doi:10.1016/j.bjp.2019.01.001 · Cited by 46 · see citing works

Herbal Treatment for Dermatologic Disorders

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Comparison of Partial Least Squares and Artificial Neural Network for the prediction of antioxidant activity in extract of Pegaga (Centella) varieties from 1H Nuclear Magnetic Resonance spectroscopy

Maulidiani, M., Abas, F., Khatib, A., Shitan, M., Shaari, K., & Lajis, N. H. (2013) · Food Research International · doi:10.1016/j.foodres.2013.08.029 · Cited by 44 · see citing works

Burn-Induced Local and Systemic Immune Response: Systematic Review and Meta-Analysis of Animal Studies

Mulder, P. P. G., Koenen, H. J. P. M., Vlig, M., Joosten, I., de Vries, R. B. M., & Boekema, B. K. H. L. (2022) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2022.05.004 · Cited by 41 · see citing works

How to Promote Skin Repair? In-Depth Look at Pharmaceutical and Cosmetic Strategies

Torres, A., Rego, L., Martins, M., Ferreira, M. S., Cruz, M. T., Sousa, E., & Almeida, I. F. (2023) · Pharmaceuticals · doi:10.3390/ph16040573 · Cited by 42 · see citing works

A Systematic Review of the Efficacy ofCentella asiaticafor Improvement of the Signs and Symptoms of Chronic Venous Insufficiency

Chong, N. J., & Aziz, Z. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/627182 · Cited by 34 · see citing works

CENTELLA ASIATICA: A CONCISE DRUG REVIEW WITH PROBABLE CLINICAL USES

Tiwari, S., Gehlot, S., & Gambhir, I. S. (2011) · Cited by 32 · see citing works

Asiatic acid: a review on its polypharmacological properties and therapeutic potential against various Maladies

Mushtaq, Z., Imran, M., Hussain, M., Saeed, F., Imran, A., Umar, M., Abdelgawad, M. A., El-Ghorab, A. H., Ahmed, A., Alsagaby, S. A., et al. (2023) · International Journal of Food Properties · doi:10.1080/10942912.2023.2209702 · Cited by 31 · see citing works

A Prospective Randomized, Controlled, Double‐Blind Trial of the Efficacy Using Centella Cream for Scar Improvement

Jenwitheesuk, K., Rojsanga, P., Chowchuen, B., & Surakunprapha, P. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/9525624 · Cited by 29 · see citing works

A mechanistic perspective on the role of phytoconstituents-based pharmacotherapeutics and their topical formulations in chronic wound management

Pattnaik, S., Mohanty, S., Sahoo, S. K., & Mohanty, C. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104546 · Cited by 29 · see citing works

Asiaticoside delays senescence and attenuate generation of ROS in UV‑exposure cells through regulates TGF‑β1/Smad pathway

Jiang, H., Zhou, X., & Chen, L. (2022) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2022.11603 · Cited by 27 · see citing works

Protective effect of ginsenosides Rg 2 and Rh 1 on oxidation-induced impairment of erythrocyte membrane properties

Samukawa, K., Suzuki, Y., Ohkubo, N., Aoto, M., Sakanaka, M., & Mitsuda, N. (2008) · Biorheology · doi:10.3233/bir-2008-0516 · Cited by 27 · see citing works

Preparation, Development, and Scale-Up of Standardized Pentacyclic Triterpenoid-Rich Extract from Centella asiatica (L.) Urb. and Study of Its Wound Healing Activity

Rachpirom, M., Pichayakorn, W., & Puttarak, P. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e17807 · Cited by 26 · see citing works

Anti inflammatory effect of asiaticoside on human umbilical vein endothelial cells induced by ox-LDL

Li, J., Hai-tao, W., Wang, Q., Fu, Z., Nan, Z., & Xuezheng, Z. (2018) · Cytotechnology · doi:10.1007/s10616-018-0198-4 · Cited by 26 · see citing works

Effects of topical applications of porcine acellular urinary bladder matrix and Centella asiatica extract on oral wound healing in a rat model

Camacho‐Alonso, F., Torralba-Ruiz, M. R., García‐Carrillo, N., Lacal‐Luján, J., Martínez-Díaz, F., & Sánchez‐Siles, M. (2018) · Clinical Oral Investigations · doi:10.1007/s00784-018-2620-x · Cited by 26 · see citing works

Strategies for Improving Healing of the Gastric Epithelium Using Oral Solid Dispersions Loaded with Pentacyclic Triterpene–Rich Centella Extract

Wannasarit, S., Puttarak, P., Kaewkroek, K., & Wiwattanapatapee, R. (2019) · AAPS PharmSciTech · doi:10.1208/s12249-019-1488-7 · Cited by 26 · see citing works

Effect of asiaticoside on the healing of skin wounds in the carp Cirrhinus mrigala: An immunohistochemical investigation

Verma, N., Kumari, U., Mittal, S., & Mittal, S. (2017) · Tissue and Cell · doi:10.1016/j.tice.2017.10.005 · Cited by 25 · see citing works

Asiatic acid abridges pre-neoplastic lesions, inflammation, cell proliferation and induces apoptosis in a rat model of colon carcinogenesis

Siddique, A. I., Mani, V., Renganathan, S., Ayyanar, R., Nagappan, A., & Nalini, N. (2017) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2017.10.024 · Cited by 25 · see citing works

Preparation and evaluation of PEGylated asiatic acid nanostructured lipid carriers on anti-fibrosis effects

Chen, X., Zhang, Y., Zhao, P., Chen, Y., Zhou, Y., Wang, S., & Yin, L. (2019) · Drug Development and Industrial Pharmacy · doi:10.1080/03639045.2019.1701002 · Cited by 25 · see citing works

Production of asiaticoside from centella (Centella asiatica L. Urban) cells in bioreactor

Lộc, N. H., & Nhat, N. T. D. (2013) · Asian Pacific Journal of Tropical Biomedicine · doi:10.1016/s2221-1691(13)60159-8 · Cited by 25 · see citing works

Current Updates on Centella asiatica: Phytochemistry, Pharmacology and Traditional Uses

Md, M. S. (2013) · Medicinal Plant Research · doi:10.5376/mpr.2013.03.0004 · Cited by 24 · see citing works

Effects of Asiaticoside Treatment on the Survival of Random Skin Flaps in Rats

Feng, X., Huang, D., Lin, D., Zhu, L., Zhang, M., Chen, Y., & Wu, F. (2021) · Journal of Investigative Surgery · doi:10.1080/08941939.2019.1584255 · Cited by 23 · see citing works

Morphological Description and Ethnobotanical Review of the Orphan Crop Myin-Hkwa (Centella asiatica L.) From Myanmar

Shukurova, M. K., Myint, D., Yi, S. S., Ohm, M. S., & Watanabe, K. (2021) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2021.680862 · Cited by 23 · see citing works

The Efficacy of Combined Herbal Extracts Gel in Reducing Scar Development at a Split-Thickness Skin Graft Donor Site

Chuangsuwanich, A., Arunakul, S., & Kamnerdnakta, S. (2013) · Aesthetic Plastic Surgery · doi:10.1007/s00266-013-0140-2 · Cited by 22 · see citing works

The Electrical Conductivity of Nutrient Solution Influenced the Growth, Centellosides Content and Gene Expression of Centella asiatica in a Hydroponic System

Shawon, M. R. A., Azad, M. O. K., Ryu, B. R., Na, J.-K., & Choi, K. (2023) · Agriculture · doi:10.3390/agriculture13122236 · Cited by 20 · see citing works

A phase II trial of a transmucosal herbal patch for the treatment of gingivitis

Grbic, J. T., Wexler, I. D., Celenti, R. S., Altman, J., & Saffer, A. (2011) · The Journal of the American Dental Association · doi:10.14219/jada.archive.2011.0086 · Cited by 20 · see citing works

AA-PMe, a novel asiatic acid derivative, induces apoptosis and suppresses proliferation, migration, and invasion of gastric cancer cells

Jing, Y., Wang, G., Ge, Y., Xu, M., Tang, S., & Gong, Z. (2016) · OncoTargets and Therapy · doi:10.2147/ott.s98849 · Cited by 16 · see citing works

Dissolvable microneedles loaded with asiaticoside nanocrystals stabilized by Panax Notoginseng saponins for hypertrophic scar treatment

Huang, H., Shen, Y., Yang, X., Hou, C., Ke, X., & Yang, R. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.105854 · Cited by 16 · see citing works

Anti-Proliferative Activities of Centella Asiatica Extracts on Human Respiratory Epithelial Cells in vitro

Mutua, P. M., Gicheru, M. M., Makanya, A. N., & Kiama, S. G. (2013) · International Journal of Morphology · doi:10.4067/s0717-95022013000400028 · Cited by 16 · see citing works

Synthesis and evaluation of asiatic acid derivatives as anti-fibrotic agents: Structure/activity studies

Li, Y., Yang, F., Yuan, M., Jiang, L., Yuan, L., Zhang, X., Li, Y., Dong, L., Bao, X., & Yin, S. (2014) · Steroids · doi:10.1016/j.steroids.2014.11.001 · Cited by 15 · see citing works

Accession in Centella asiatica; Current Understanding and Future Knowledge

Gbolahan, B., Abiola, A., Kamaldin, J., Ahmad, M. A., & Atanassova, M. (2016) · Journal of Pure and Applied Microbiology · doi:10.22207/jpam.10.4.02 · Cited by 15 · see citing works

Madecassoside induces apoptosis of keloid fibroblasts via a mitochondrial‐dependent pathway

Song, J., Dai, Y., Bian, D., Zhang, H., Xu, X., Xia, Y., & Gong, Z. (2010) · Drug Development Research · doi:10.1002/ddr.20432 · Cited by 15 · see citing works

Harnessing Plant Bioactive Compounds in Biomaterial Scaffolds for Advanced Wound Healing: A Comprehensive Review

Sabarudin, N. S., Ghani, N. A., Ahmat, N., Harlin, E. W., Hao, L. Q., Handajani, J., Nor, F. M., Fadilah, N. I. M., Maarof, M., & Fauzi, M. (2025) · Biomedicines · doi:10.3390/biomedicines13102414 · Cited by 12 · see citing works

New alternative therapy for orofacial localized scleroderma

Liu, X. S., Gao, Y., Zheng, L. W., & Hua, H. (2010) · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology · doi:10.1016/j.tripleo.2010.04.004 · Cited by 14 · see citing works

Asiaticoside alleviates atherosclerosis progression by suppressing RhoF–NF-κB/MAPK signaling and inflammation in macrophages

Wang, J., Lei, L., Wang, S., & Sun, Y. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.157137 · Cited by 13 · see citing works

A Convergent Synthesis of the Triterpene Saponin Asiaticoside

Shao, W., Cao, X., Shen, L., Zhang, F., & Yu, B. (2017) · Asian Journal of Organic Chemistry · doi:10.1002/ajoc.201700153 · Cited by 13 · see citing works

Current Concepts in Scar Evolution and Control

Widgerow, A. D. (2010) · Aesthetic Plastic Surgery · doi:10.1007/s00266-010-9635-2 · Cited by 12 · see citing works

Asiatic Acid Inhibits Adipogenic Differentiation of Bone Marrow Stromal Cells

Li, Z., Piao, C., Sun, H., Ren, X.-S., & Bai, Y.-S. (2013) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-013-9725-2 · Cited by 11 · see citing works

Analysis of genetic diversity of Centella asiatica using SSR markers

Sakthipriya, M., Vishnu, S. S., Sujith, S. S., Kumar, P. R., & Sabu, K. K. (2018) · International Journal of Applied Sciences and Biotechnology · doi:10.3126/ijasbt.v6i2.19583 · Cited by 10 · see citing works

Therapeutic applications of natural products in the management of venous diseases: a comprehensive review

Mostafa, R. E., Ali, D. E., El‐Shiekh, R. A., Elalfy, A., Hafeez, M. S. A. E., Reda, A. M., & Fayek, N. M. (2025) · Inflammopharmacology · doi:10.1007/s10787-025-01688-z · Cited by 9 · see citing works

Triterpenoid Centellosides: Bioactivities and Uses in Healthcare Application

Hashim, P. (2013) · Springer eBooks · doi:10.1007/978-3-642-22144-6_167 · Cited by 9 · see citing works

Proangiogenic Potential of Medicinal Plants in Wound Healing

Kasote, D. M., Ahmad, A., & Viljoen, A. M. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800874-4.00006-4 · Cited by 9 · see citing works

Saponins from Saffron Corms Inhibit the Gene Expression and Secretion of Pro-Inflammatory Cytokines

Keller, M., Fankhauser, S. C., Giezendanner, N., König, M., Keresztes, F., Danton, O., Fertig, O., Marcourt, L., Hamburger, M. O., Butterweck, V., et al. (2021) · Journal of Natural Products · doi:10.1021/acs.jnatprod.0c01220 · Cited by 8 · see citing works

Advancement in wound healing treatment using functional nanocarriers

Lukhey, M. S., & Shende, P. K. (2022) · International Journal of Polymeric Materials · doi:10.1080/00914037.2022.2099393 · Cited by 8 · see citing works

Simultaneous determination of four active compounds in Centella asiatica by supramolecular solvent-based extraction coupled with high performance liquid chromatography-tandem mass spectrometry

Yuan, Y., Qiao, Y., Zheng, X. X., Yu, X., Dong, Y., Wang, H., & Sun, L. (2023) · Journal of Chromatography A · doi:10.1016/j.chroma.2023.464298 · Cited by 8 · see citing works

Asiaticoside: A Wonderful Herbal Component of Versatile Therapeutic Benefits with Special Reference to Wound Healing Activity

Kumar, M., & Uttam Kumar, M. (2021) · Journal of Clinical & Experimental Dermatology Research · doi:10.35248/2155-9554.21.s9.571 · Cited by 7 · see citing works

Aktivitas pegagan (Centella asiatica) pada dermatologi

Fernenda, L., Ramadani, A. P., & Syukri, Y. (2023) · Jurnal Sains Farmasi & Klinis · doi:10.25077/jsfk.9.3.237-244.2022 · Cited by 7 · see citing works

The Effect of Production and Post-Harvest Processing Practices on Quality Attributes in Centella asiatica (L.) Urban—A Review

Singh, R., Kharsyntiew, B., Sharma, P., Sahoo, U. K., Sarangi, P. K., Prus, P., & Imbrea, F. (2023) · Agronomy · doi:10.3390/agronomy13081999 · Cited by 7 · see citing works

Anti-proliferative activities of Centella asiatica extracts on human respiratory epithelial cells in vitro

Heikal, M. Y. M., Mariam, H., Ilham, A. M., Fong, C. M., Aminuddin, B. S., & Ruszymah, B. (2014) · Journal of Medicinal Plants Research · doi:10.5897/jmpr12.660 · Cited by 7 · see citing works

Validation of Fespixon in Postoperative Scar Cosmesis Using Quantitative Digital Photography Analysis

Huang, T.-R., Chen, S.-G., Chen, J.-C., & Liu, S. (2023) · Aesthetic Surgery Journal · doi:10.1093/asj/sjad005 · Cited by 6 · see citing works

Activité cicatrisante de l’extrait aqueux des feuilles de Elaeis guineensis Jacq. (Arecaceae)

Sene, M., Barboza, F. S., Top, B., Mamadou, N., Sarr, A., Alioune Dior, F. A. L. L., & Sy, G. Y. (2020) · International Journal of Biological and Chemical Sciences · doi:10.4314/ijbcs.v14i3.3 · Cited by 6 · see citing works

Combination treatment with asiaticoside and rapamycin: A new hope for in-stent restenosis

GUO, T., FANG, M., Zhang, D., & Li, X. (2013) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2013.1155 · Cited by 6 · see citing works

Effect of Roasting and Kneading on Antioxidant Activity and Consumer Acceptance towards Asiatic Pennywort Tea

Ploenkutham, R., Sripromma, P., Amornraksa, S., Yasurin, P., & Soontrunnarudrungsri, A. (2018) · MATEC Web of Conferences · doi:10.1051/matecconf/201818701004 · Cited by 6 · see citing works

Antidiabetic and Antioxidant Activities of Decoctions of Coccinia grandis Linn. and Centella asiatica (L.) on Alloxan-induced Diabetic rats

Islam, M. S., Parvin, S., Uddin, M. N., & Mazid, M. A. (2015) · Bangladesh Pharmaceutical Journal · doi:10.3329/bpj.v17i1.22322 · Cited by 6 · see citing works

Molecular authentication of Centella asiatica products by a novel real-time PCR approach: Influence of plant matrix

Biltes, R., Villa, C., Costa, J. S., & Mafra, I. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.106395 · Cited by 5 · see citing works

Crystallization of Asiaticoside from Total Triterpenoid Saponins of Centella Asiatica in a Methanol + Water System

Fu, J., Zheng, X.-F., & Lü, X. (2014) · Industrial & Engineering Chemistry Research · doi:10.1021/ie502657h · Cited by 5 · see citing works

Asiaticoside A for the modulation of 1-TbAd- a potential target and ligand for extensive drug resistance Mycobacterium tuberculosis

Tilwani, K., Patel, A., Patel, M., Sojitra, P., & Dave, G. (2023) · AMB Express · doi:10.1186/s13568-023-01616-w · Cited by 5 · see citing works

Injectable Microparticle-containing hydrogel with controlled release of bioactive molecules for facial rejuvenation

Lee, S., Baek, S., Kim, D., Park, S., Kim, J. H., Jung, J., Lee, J., Park, G.-M., Park, C. G., & Han, D. K. (2023) · Materials Today Bio · doi:10.1016/j.mtbio.2023.100890 · Cited by 5 · see citing works

Hydrogel-based delivery systems loaded with natural active compounds for endometrial injury repair: a review of recent advances

Zhou, X., Yi, Q., & Yang, L. (2025) · Biomedical Materials · doi:10.1088/1748-605x/adde09 · Cited by 4 · see citing works

Surgery and Medicinal Plants: A review of important indigenous medicinal plants of Iran for burn wound healing

Sharifian, M., Hasanvand, A., Basati, G., & Abbaszadeh, S. (2019) · Plant Science Today · doi:10.14719/pst.2019.6.2.552 · Cited by 4 · see citing works

Development and comprehensive evaluation of Centella asiatica loaded polyvinyl alcohol films for enhanced wound healing applications

Ayyanar, C. B., Jaibharathraj, N., Prasaath, K. S., Bal, T., Fahaduddin, Devika, K., Rinusuba, V., Santhini, E., Bindhu, J., Thomas, S., et al. (2026) · Materials Chemistry and Physics · doi:10.1016/j.matchemphys.2026.132109 · Cited by 3 · see citing works

AQbD enabled analytical method development and validation for simultaneous estimation of Asiaticoside (AC) and Chlorhexidine (CHX) in nanostructured lipid carriers

Kumar, A., Chauhan, A., Kumar, D., Tripathi, A. K., Awasthi, A., Singh, T., Kondaveeti, S. B., & Kumar, M. (2026) · Journal of Pharmaceutical Innovation · doi:10.1007/s12247-026-10506-0 · Cited by 3 · see citing works

Asiaticoside Attenuates Burn Serum-induced Human Dermal Microvascular Endothelial Cell Injury via Regulating ACTN4-mediated p38-MAPK/p53 Signaling Pathway

Wang, S., Tan, J., Ying, W., Sun, T., Sun, P., & Chen, C. (2024) · Journal of Biological Regulators and Homeostatic Agents/Journal of Biological Regulators & Homeostatic Agents · doi:10.23812/j.biol.regul.homeost.agents.20243801.54

Burn wound healing properties of asiaticoside and madecassoside

Hou, Q., Li, M., Lu, Y., Liu, D., & Li, C.-C. (2016) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2016.3459 · Cited by 69 · see citing works

Influence of asiaticoside on the expression of Cyclin,proliferating cell nuclear antigen in wounds tissue healing of burned rat

Li, T. X. (2005) · Zhonghua shiyan waike zazhi

Madecassoside Isolated from<i>Centella asiatica</i>Herbs Facilitates Burn Wound Healing in Mice

Liu, M., Dai, Y., Li, Y., Luo, Y., Huang, F., Gong, Z., & Meng, Q. (2008) · Planta Medica · doi:10.1055/s-2008-1074533 · Cited by 142 · see citing works

Identification of Major Active Ingredients Responsible for Burn Wound Healing of<i>Centella asiatica</i>Herbs

Wu, F., Bian, D., Xia, Y., Gong, Z., Tan, Q., Chen, J., & Dai, Y. (2012) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2012/848093 · Cited by 105 · see citing works