Trophic Interactions Between Astroglial Cells and Hippocampal Neurons in Culture

Growth of a rat neuroblastoma cell line in serum-free supplemented medium.

Bottenstein, J. E., & SATO, G. H. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.1.514 · Cited by 2,282 · see citing works

Rat hippocampal neurons in dispersed cell culture.

Banker, G. A., & Cowan, W. M. (1977) · Brain Research · doi:10.1016/0006-8993(77)90594-7 · Cited by 1,110 · see citing works

Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures.

Booher, J., & Sensenbrenner, M. (1972) · PubMed · Cited by 760 · see citing works

Adult rat brain astrocytes support survival of both NGF-dependent and NGF-insensitive neurones

Lindsay, R. M. (1979) · Nature · doi:10.1038/282080a0 · Cited by 373 · see citing works

Trophic Mechanisms in the Peripheral Nervous System

Varon, S. S., & Bunge, R. P. (1978) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.01.030178.001551 · Cited by 326 · see citing works

Further observations on hippocampal neurons in dispersed cell culture

Banker, G. A., & Cowan, W. M. (1979) · Journal of Comparative Neurology · doi:10.1002/cne.901870302 · Cited by 285 · see citing works

Nerve Growth Factor

Bradshaw, R. A. (1978) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.47.070178.001203 · Cited by 246 · see citing works

Neuron-glia interactions.

Varon, S. S., & Gg, S. (1979) · PubMed · Cited by 244 · see citing works

Induction of neurite outgrowth by a conditioned-medium factor bound to the culture substratum

Collins, F. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.10.5210 · Cited by 241 · see citing works

Survival and development in culture of dissociated parasympathetic neurons from ciliary ganglia

Helfand, S. L., Smith, G. A., & Wessells, N. K. (1976) · Developmental Biology · doi:10.1016/0012-1606(76)90174-3 · Cited by 177 · see citing works

New factor released by cultured glioma cells supporting survival and growth of sensory neurones

Barde, Y., Lindsay, R. M., Monard, D., & Thoenen, H. (1978) · Nature · doi:10.1038/274818a0 · Cited by 171 · see citing works

Enzymatic and morphological properties of primary rat brain astrocyte cultures, and enzyme development in vivo

Kimelberg, H. K., Narumi, S., & Bourke, R. S. (1978) · Brain Research · doi:10.1016/0006-8993(78)91128-9 · Cited by 160 · see citing works

Axon initiation by ciliary neurons in culture

Collins, F. (1978) · Developmental Biology · doi:10.1016/0012-1606(78)90178-1 · Cited by 153 · see citing works

Cation transport and membrane potential properties of primary astroglial cultures from neonatal rat brains

Kimelberg, H. K., Bowman, C. L., Biddlecome, S., & Bourke, R. S. (1979) · Brain Research · doi:10.1016/0006-8993(79)90470-0 · Cited by 141 · see citing works

DETERMINATION OF BRAIN‐SPECIFIC ANTIGENS IN SHORT TERM CULTIVATED RAT ASTROGLIAL CELLS AND IN RAT SYNAPTOSOMES

Bock, E., Jørgensen, O. S., Dittmann, L., & Eng, L. F. (1975) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1975.tb04419.x · Cited by 140 · see citing works

Survival and development of ciliary ganglion neurones grown alone in cell culture

Nishi, R., & Berg, D. K. (1979) · Nature · doi:10.1038/277232a0 · Cited by 126 · see citing works

Non-equivalence of conditioned medium and nerve growth factor for sympathetic, parasympathetic, and sensory neurons

Helfand, S. L., Riopelle, R. J., & Wessells, N. K. (1978) · Experimental Cell Research · doi:10.1016/0014-4827(78)90085-x · Cited by 122 · see citing works

Secretion of nerve growth factor by central nervous system glioma cells in culture.

Murphy, R. A., Oger, J. J.-F., Saide, J. D., Blanchard, M. H., Arnason, B. G. W., Hogan, C., & Pantazis, N. J. (1977) · The Journal of Cell Biology · doi:10.1083/jcb.72.3.769 · Cited by 90 · see citing works

Nerve Growth Factor in Rat Glioma Cells

Longo, A. M., & Penhoet, E. E. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.6.2347 · Cited by 88 · see citing works

Distinction between nerve growth factor and glial factor

Monard, D., Stöckel, K., Goodman, R., & Thoenen, H. (1975) · Nature · doi:10.1038/258444a0 · Cited by 63 · see citing works

Morphology of dissociated hippocampal cultures from fetal mice

Peacock, J. H., Rush, D. F., & Mathers, L. H. (1979) · Brain Research · doi:10.1016/0006-8993(79)91027-8 · Cited by 60 · see citing works

Implication of a nerve growth factor-like antigen in the support derived by ganglionic neurons from their homologous glia in dissociated cultures.

Varon, S. S., Raiborn, C., & Burnham, P. A. (1974) · PubMed · Cited by 52 · see citing works

Comparative effects of nerve growth factor and ganglionic nonneuronal cells on purified mouse ganglionic neurons in culture

Varon, S. S., Raiborn, C., & Burnham, P. (1974) · Journal of Neurobiology · doi:10.1002/neu.480050407 · Cited by 48 · see citing works

Culture techniques and glial-neuronal interrelationships in vitro

Varon, S. S., & Saier, M. H. (1975) · Experimental Neurology · doi:10.1016/0014-4886(75)90174-0 · Cited by 48 · see citing works

Stimulatory Role of Glial Cells on the Differentiation of Dissociated Chick Embryo Encephalon Cells

Touzet, N., & Sensenbrenner, M. (2007) · Developmental Neuroscience · doi:10.1159/000112568 · Cited by 20 · see citing works

Neurotoxic reactive astrocytes are induced by activated microglia

Liddelow, S. A., Guttenplan, K. A., Clarke, L. E., Bennett, F. C., Bohlen, C. J., Schirmer, L., Bennett, M. L., Münch, A. E., Chung, W.-S., Peterson, T. C., et al. (2017) · Nature · doi:10.1038/nature21029 · Cited by 7,971 · see citing works

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

Zhang, Y., Sloan, S. A., Clarke, L. E., Caneda, C., Plaza, C. A., Blumenthal, P. D., Vogel, H., Steinberg, G. K., Edwards, M. S. B., Li, G., et al. (2016) · Neuron · doi:10.1016/j.neuron.2015.11.013 · Cited by 2,295 · see citing works

The establishment of polarity by hippocampal neurons in culture.

Dotti, C., Sullivan, C., & Banker, G. (1988) · The Journal of Neuroscience · doi:10.1523/jneurosci.08-04-01454.1988 · Cited by 1,862 · see citing works

Astroglia induce neurogenesis from adult neural stem cells

Song, H., Stevens, C. F., & Gage, F. H. (2002) · Nature · doi:10.1038/417039a · Cited by 1,452 · see citing works

Molecular profile of reactive astrocytes—Implications for their role in neurologic disease

Eddleston, M., & Mucke, L. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90380-x · Cited by 1,422 · see citing works

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

Barres, B. A. (2008) · Neuron · doi:10.1016/j.neuron.2008.10.013 · Cited by 1,352 · see citing works

Normal aging induces A1-like astrocyte reactivity

Clarke, L. E., Liddelow, S. A., Chakraborty, C., Münch, A. E., Heiman, M., & Barres, B. A. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1800165115 · Cited by 1,237 · see citing works

Leukocyte Infiltration, Neuronal Degeneration, and Neurite Outgrowth after Ablation of Scar-Forming, Reactive Astrocytes in Adult Transgenic Mice

Bush, T. G., Puvanachandra, N., Horner, C. H., Polito, A., Ostenfeld, T., Svendsen, C. N., Mucke, L., Johnson, M. H., & Sofroniew, M. V. (1999) · Neuron · doi:10.1016/s0896-6273(00)80781-3 · Cited by 1,116 · see citing works

Cell Biology of Astrocyte-Synapse Interactions

Allen, N. J., & Eroğlu, Ç. (2017) · Neuron · doi:10.1016/j.neuron.2017.09.056 · Cited by 1,031 · see citing works

Astrocytes Control Synapse Formation, Function, and Elimination

Chung, W.-S., Allen, N. J., & Eroglu, C. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020370 · Cited by 839 · see citing works

Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates

Volpicelli-Daley, L. A., Luk, K. C., & Lee, V. M.-Y. (2014) · Nature Protocols · doi:10.1038/nprot.2014.143 · Cited by 731 · see citing works

Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension.

Walicke, P. A., Cowan, W. M., Ueno, N., Baird, A., & Guillemin, R. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.9.3012 · Cited by 730 · see citing works

Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture.

Morrison, R. S., Sharma, A., de Vellis, J., & Bradshaw, R. A. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.19.7537 · Cited by 684 · see citing works

Astrocyte heterogeneity: an underappreciated topic in neurobiology

Zhang, Y., & Barres, B. A. (2010) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.06.005 · Cited by 548 · see citing works

Basic and acidic fibroblast growth factors have trophic effects on neurons from multiple CNS regions

Walicke, P. A. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-07-02618.1988 · Cited by 527 · see citing works

The Indispensable Roles of Microglia and Astrocytes during Brain Development

Reemst, K., Noctor, S. C., Lucassen, P. J., & Hol, E. M. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00566 · Cited by 516 · see citing works

Synaptic degeneration in Alzheimer disease

Tzioras, M., McGeachan, R. I., Durrant, C. S., & Spires-Jones, T. L. (2023) · Nature Reviews Neurology · doi:10.1038/s41582-022-00749-z · Cited by 504 · see citing works

Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer

Lim, J. S., Ibaseta, A., Fischer, M. M., Cancilla, B., O’Young, G., Cristea, S., Luca, V. C., Yang, D., Jahchan, N. S., Hamard, C., et al. (2017) · Nature · doi:10.1038/nature22323 · Cited by 482 · see citing works

Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture

Mattson, M., Murrain, M., Guthrie, P., & Kater, S. (1989) · The Journal of Neuroscience · doi:10.1523/jneurosci.09-11-03728.1989 · Cited by 409 · see citing works

Non–cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology

Ballas, N., Lioy, D. T., Grunseich, C., & Mandel, G. (2009) · Nature Neuroscience · doi:10.1038/nn.2275 · Cited by 466 · see citing works

NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis

Cheng, B., & Mattson, M. P. (1991) · Neuron · doi:10.1016/0896-6273(91)90347-3 · Cited by 460 · see citing works

Proliferation, differentiation, and long-term culture of primary hippocampal neurons.

Ray, J., Peterson, D. A., Schinstine, M., & Gage, F. H. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.8.3602 · Cited by 457 · see citing works

Development of a Method for the Purification and Culture of Rodent Astrocytes

Foo, L. C., Allen, N. J., Bushong, E. A., Ventura, P. B., Chung, W.-S., Zhou, L., Cahoy, J. D., Daneman, R., Zong, H., Ellisman, M. H., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.07.022 · Cited by 433 · see citing works

Polarized sorting of viral glycoproteins to the axon and dendrites of hippocampal neurons in culture

Dotti, C. G., & Simons, K. (1990) · Cell · doi:10.1016/0092-8674(90)90240-f · Cited by 427 · see citing works

Experimental observations on the development of polarity by hippocampal neurons in culture.

Goslin, K., & Banker, G. A. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.108.4.1507 · Cited by 416 · see citing works

Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors

Schwab, M. E., & Thoenen, H. (1985) · Journal of Neuroscience · doi:10.1523/jneurosci.05-09-02415.1985 · Cited by 413 · see citing works

Survival and growth of hippocampal neurons in defined medium at low density: advantages of a sandwich culture technique or low oxygen

Brewer, G. J., & Cotman, C. W. (1989) · Brain Research · doi:10.1016/0006-8993(89)90144-3 · Cited by 376 · see citing works

Immunocytochemical localization of tubulin and microtubule-associated protein 2 during the development of hippocampal neurons in culture

Caceres, A., Banker, G., & Binder, L. (1986) · The Journal of Neuroscience · doi:10.1523/jneurosci.06-03-00714.1986 · Cited by 367 · see citing works

Glia Accumulate Evidence that Actions Are Futile and Suppress Unsuccessful Behavior

Mu, Y., Bennett, D., Rubinov, M., Narayan, S., Yang, C.-T., Tanimoto, M., Mensh, B. D., Looger, L. L., & Ahrens, M. B. (2019) · Cell · doi:10.1016/j.cell.2019.05.050 · Cited by 361 · see citing works

An electron microscopic study of the development of axons and dendrites by hippocampal neurons in culture. I. Cells which develop without intercellular contacts

Bartlett, W., & Banker, G. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-08-01944.1984 · Cited by 348 · see citing works

Astrocyte regulation of synaptic behavior

Allen, N. J. (2014) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100913-013053 · Cited by 343 · see citing works

Oligodendrocytes promote neuronal survival and axonal length by distinct intracellular mechanisms: a novel role for oligodendrocyte-derived glial cell line-derived neurotrophic factor

Wilkins, A., Majed, H., Layfield, R., Compston, A., & Chandran, S. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-12-04967.2003 · Cited by 337 · see citing works

Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF

Ip, N. Y., Li, Y., Yancopoulos, G. D., & Lindsay, R. M. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-08-03394.1993 · Cited by 330 · see citing works

Glial heterogeneity may define the three-dimensional shape of mouse mesencephalic dopaminergic neurones

Denis‐Donini, S., Glowinski, J., & Prochiantz, A. (1984) · Nature · doi:10.1038/307641a0 · Cited by 323 · see citing works

MAP2 is localized to the dendrites of hippocampal neurons which develop in culture

Cáceres, A., Banker, G. A., Steward, O., Binder, L. I., & Payne, M. R. (1984) · Developmental Brain Research · doi:10.1016/0165-3806(84)90167-6 · Cited by 320 · see citing works

The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia [published erratum appears in J Neurosci 1992 Mar;12(3):685]

Engele, J., & Bohn, M. (1991) · Journal of Neuroscience · doi:10.1523/jneurosci.11-10-03070.1991 · Cited by 303 · see citing works

Trophic Stimulation of Cultured Neurons from Neonatal Rat Brain by Epidermal Growth Factor

Morrison, R. S., Kornblum, H. I., Leslie, F. M., & Bradshaw, R. A. (1987) · Science · doi:10.1126/science.3498986 · Cited by 294 · see citing works

Studies of adhesion molecules mediating interactions between cells of peripheral nervous system indicate a major role for L1 in mediating sensory neuron growth on Schwann cells in culture.

Seilheimer, B., & Schachner, M. (1988) · The Journal of Cell Biology · doi:10.1083/jcb.107.1.341 · Cited by 285 · see citing works

Synaptic Integration of Adult-Born Hippocampal Neurons Is Locally Controlled by Astrocytes

Sultan, S., Li, L., Moss, J., Petrelli, F., Cassé, F., Gebara, E., Lopatar, J., Pfrieger, F. W., Bezzi, P., Bischofberger, J., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.10.037 · Cited by 284 · see citing works

Astrocytes Provide Cysteine to Neurons by Releasing Glutathione

Wang, X. F., & Cynader, M. S. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0741434.x · Cited by 281 · see citing works

Role of the lesion scar in the response to damage and repair of the central nervous system

Kawano, H., Kimura‐Kuroda, J., Komuta, Y., Yoshioka, N., Li, H. P., Kawamura, K., Li, Y., & Raisman, G. (2012) · Cell and Tissue Research · doi:10.1007/s00441-012-1336-5 · Cited by 275 · see citing works

Glial and Neuroimmune Mechanisms as Critical Modulators of Drug Use and Abuse

Lacagnina, M. J., Rivera, P. D., & Bilbo, S. D. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.121 · Cited by 271 · see citing works

Long‐term culture of mouse cortical neurons as a model for neuronal development, aging, and death

Lesuisse, C., & Martin, L. J. (2002) · Journal of Neurobiology · doi:10.1002/neu.10037 · Cited by 263 · see citing works

Cell-cell interactions influence survival and differentiation of purified purkinje cells in vitro

Hatten, C. A. B. E., Blazeski, R., & Mason, C. A. (1994) · Neuron · doi:10.1016/0896-6273(94)90268-2 · Cited by 260 · see citing works

Ca2+ waves in astrocytes

Cornell-Bell, A. H., & Finkbeiner, S. M. (1991) · Cell Calcium · doi:10.1016/0143-4160(91)90020-f · Cited by 257 · see citing works

Suppression of MAP2 in cultured cerebeller macroneurons inhibits minor neurite formation

Cáceres, A., Mautino, J., & Kosik, K. S. (1992) · Neuron · doi:10.1016/0896-6273(92)90025-9 · Cited by 256 · see citing works

Fibroblast growth factors stimulate nerve growth factor synthesis and secretion by astrocytes

Yoshida, K., & Gage, F. H. (1991) · Brain Research · doi:10.1016/0006-8993(91)90385-9 · Cited by 245 · see citing works

Contrasting the Glial Response to Axon Injury in the Central and Peripheral Nervous Systems

Lutz, A. B., & Barres, B. A. (2014) · Developmental Cell · doi:10.1016/j.devcel.2013.12.002 · Cited by 229 · see citing works

Astrocytes are important for sprouting in the septohippocampal circuit

Gage, F. H., Olejniczak, P. W., & Armstrong, D. M. (1988) · Experimental Neurology · doi:10.1016/0014-4886(88)90073-8 · Cited by 227 · see citing works

Astrocyte-immune cell interactions in physiology and pathology

Han, R. T., Kim, R. D., Molofsky, A. V., & Liddelow, S. A. (2021) · Immunity · doi:10.1016/j.immuni.2021.01.013 · Cited by 223 · see citing works

Neuronal–glial interactions and behaviour

Laming, P. R., Kimelberg, H. K., Robinson, S. R., Salm, A. K., Hawrylak, N., Müller, C. M., Roots, B. I., & Ng, K. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(99)00080-9 · Cited by 220 · see citing works

Changes in the distribution of GAP-43 during the development of neuronal polarity

Goslin, K., Schreyer, D., Skene, J. H. P., & Banker, G. A. (1990) · Journal of Neuroscience · doi:10.1523/jneurosci.10-02-00588.1990 · Cited by 217 · see citing works

Primary support cultures of hippocampal and substantia nigra neurons

Fath, T., Ke, Y. D., Gunning, P. W., Götz, J., & Ittner, L. M. (2008) · Nature Protocols · doi:10.1038/nprot.2008.199 · Cited by 210 · see citing works

CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes

Barbar, L., Jain, T., Zimmer, M., Kruglikov, I., Sadick, J. S., Wang, M., Kalpana, K., Rose, I. V. L., Burstein, S. R., Rusielewicz, T., et al. (2020) · Neuron · doi:10.1016/j.neuron.2020.05.014 · Cited by 206 · see citing works

Nonneuronal cells mediate neurotrophic action of vasoactive intestinal peptide.

Brenneman, D. E., Neale, E. A., Foster, G. A., d'Autremont, S. W., & Westbrook, G. L. (1987) · The Journal of Cell Biology · doi:10.1083/jcb.104.6.1603 · Cited by 203 · see citing works

Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines

Yoshida, K., & Gage, F. H. (1992) · Brain Research · doi:10.1016/0006-8993(92)90364-f · Cited by 202 · see citing works

Astrocyte-induced modulation of synaptic transmission

Araque, A., Sanzgiri, R. P., Parpura, V., & Haydon, P. G. (1999) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y99-076 · Cited by 201 · see citing works

Glial Fibrillary Acidic Protein and the Mesolimbic Dopamine System: Regulation by Chronic Morphine and Lewis‐Fischer Strain Differences in the Rat Ventral Tegmental Area

Beitner‐Johnson, D., Guitart, X., & Nestler, E. J. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb09814.x · Cited by 197 · see citing works

Expression of Ciliary Neurotrophic Factor and the Neurotrophins – Nerve Growth Factor, Brain‐Derived Neurotrophic Factor and Neurotrophin 3—in Cultured Rat Hippocampal Astrocytes

Rudge, J. S., Alderson, R. F., Pasnikowski, E. M., McClain, J., Ip, N. Y., & Lindsay, R. M. (1992) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1992.tb00896.x · Cited by 196 · see citing works

Mutant Superoxide Dismutase-1-Linked Familial Amyotrophic Lateral Sclerosis: Molecular Mechanisms of Neuronal Death and Protection

Ghadge, G. D., Lee, J. P., Bindokas, V. P., Jordán, J., Ma, L., Miller, R. J., & Roos, R. P. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-22-08756.1997 · Cited by 195 · see citing works

Neurite outgrowth in molluscan organ and cell cultures: the role of conditioning factor(s)

Wong, R., Hadley, R., Kater, S. B., & Hauser, G. C. (1981) · Journal of Neuroscience · doi:10.1523/jneurosci.01-09-01008.1981 · Cited by 193 · see citing works

The excitatory neurotransmitter glutamate causes filopodia formation in cultured hippocampal astrocytes

Cornell-Bell, A. H., Thomas, P. G., & Smith, S. J. (1990) · Glia · doi:10.1002/glia.440030503 · Cited by 189 · see citing works

A role for oligodendrocyte‐derived IGF‐1 in trophic support of cortical neurons

Wilkins, A., Chandran, S., & Compston, A. (2001) · Glia · doi:10.1002/glia.1094 · Cited by 185 · see citing works

Hypoxia/reoxygenation-mediated induction of astrocyte interleukin 6: a paracrine mechanism potentially enhancing neuron survival.

Maeda, Y., Matsumoto, M., Hori, O., Kuwabara, K., Ogawa, S., Yan, S. D., Ohtsuki, T., Kinoshita, T., Kamada, T., & Stern, D. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.180.6.2297 · Cited by 185 · see citing works

Axonal Elongation in Peripheral and Central Nervous System Transplants

Aguayo, A. J., David, S., Richardson, P. M., & Bray, G. M. (1982) · Advances in cellular neurobiology · doi:10.1016/b978-0-12-008303-9.50011-6 · Cited by 185 · see citing works

Vasoactive intestinal peptide: A neurotrophic releasing agent and an astroglial mitogen

Brenneman, D. E., Nicol, T., Warren, D., & Bowers, L. M. (1990) · Journal of Neuroscience Research · doi:10.1002/jnr.490250316 · Cited by 184 · see citing works

Neuron-Specific Expression of Therapeutic Proteins: Evaluation of Different Cellular Promoters in Recombinant Adenoviral Vectors

Kügler, S., Meyn, L., Holzmüller, H., Gerhardt, E., Isenmann, S., Schulz, J. B., & Bähr, M. (2001) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2000.0929 · Cited by 182 · see citing works

Induced Neuronal Cells: How to Make and Define a Neuron

Yang, N., Ng, Y. H., Pang, Z. P., Südhof, T. C., & Wernig, M. (2011) · Cell stem cell · doi:10.1016/j.stem.2011.11.015 · Cited by 180 · see citing works

GABAB receptor‐mediated inhibition of Ca2+ currents and synaptic transmission in cultured rat hippocampal neurones.

Scholz, K. P., & Miller, R. J. (1991) · The Journal of Physiology · doi:10.1113/jphysiol.1991.sp018900 · Cited by 177 · see citing works

Lineage-restricted neural precursors survive, migrate, and differentiate following transplantation into the injured adult spinal cord

Lepore, A. C., & Fischer, I. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.02.020 · Cited by 176 · see citing works

The Regulation of Astrocytic Glutamate Transporters in Health and Neurodegenerative Diseases

Todd, A., & Hardingham, G. E. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249607 · Cited by 170 · see citing works

Astrocytes prevent abnormal neuronal development in the fragile X mouse.

Jacobs, S., & Doering, L. C. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5027-09.2010 · Cited by 170 · see citing works

Gap-junctional coupling between neurons and astrocytes in primary central nervous system cultures

Fróes, M. M., Correia, A. H., Garcia-Abreu, J., Spray, D. C., de Carvalho, A. C. C., & Moura‐Neto, V. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.13.7541 · Cited by 167 · see citing works

TrkB Signaling Modulates Spine Density and Morphology Independent of Dendrite Structure in Cultured Neonatal Purkinje Cells

Shimada, A., Mason, C. A., & Morrison, M. E. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-21-08559.1998 · Cited by 164 · see citing works

Primary astrocyte cultures?a key to astrocyte function

Kimelberg, H. K. (1983) · Cellular and Molecular Neurobiology · doi:10.1007/bf00734994 · Cited by 162 · see citing works

In vivo evidence for a hippocampal adrenergic neuronotrophic factor specifically released on septal deafferentation

Björklund, A., & Stenevi, U. (1981) · Brain Research · doi:10.1016/0006-8993(81)91004-0 · Cited by 161 · see citing works

Analysis of adenosine actions on Ca2+ currents and synaptic transmission in cultured rat hippocampal pyramidal neurones.

Scholz, K. P., & Miller, R. J. (1991) · The Journal of Physiology · doi:10.1113/jphysiol.1991.sp018515 · Cited by 160 · see citing works

Neuron-Glia Interrelations

Vernodokis, A. (1988) · International review of neurobiology · doi:10.1016/s0074-7742(08)60049-5 · Cited by 159 · see citing works

Peptide growth factors protect against ischemia in culture by preventing nitric oxide toxicity

Maiese, K., Boniece, I. R., DeMeo, D. L., & Wagner, J. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-07-03034.1993 · Cited by 159 · see citing works

Neurotrophic effects of basic and acidic fibroblast growth factors are not mediated through glial cells

Walicke, P. A., & Baird, A. (1988) · Developmental Brain Research · doi:10.1016/0165-3806(88)90009-0 · Cited by 155 · see citing works

Enhanced graft survival in the hippocampus following selective denervation

Gage, F. H., & Björklund, A. (1986) · Neuroscience · doi:10.1016/0306-4522(86)90227-7 · Cited by 155 · see citing works

Excitotoxicity induced by enhanced excitatory neurotransmission in cultured hippocampal pyramidal neurons

Abele, A. E., Scholz, K. P., Scholz, W. K., & Miller, R. J. (1990) · Neuron · doi:10.1016/0896-6273(90)90053-i · Cited by 154 · see citing works

Kinesin-mediated organelle translocation revealed by specific cellular manipulations.

Feiguin, F. M., Ferreira, A., Kosik, K. S., & Cáceres, A. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.127.4.1021 · Cited by 151 · see citing works

Conditioned media derived from glial cell lines promote survival and differentiation of dopaminergic neurons in vitro: Role of mesencephalic glia

Engele, J., Schubert, D. A., & Bohn, M. C. (1991) · Journal of Neuroscience Research · doi:10.1002/jnr.490300212 · Cited by 150 · see citing works

Regulation by Interleukin‐1 of Nerve Growth Factor Secretion and Nerve Growth Factor mRNA Expression in Rat Primary Astroglial Cultures

Čarman‐Kržan, M., Vigé, X., & Wise, B. C. (1991) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1991.tb08197.x · Cited by 150 · see citing works

REACTIVE GLIOSIS

Lindsay, R. M. (1986) · Elsevier eBooks · doi:10.1016/b978-0-12-250453-2.50013-x · Cited by 150 · see citing works

Calsyntenin-1 Docks Vesicular Cargo to Kinesin-1

Konecna, A., Frischknecht, R., Kinter, J., Ludwig, A., Steuble, M., Meskenaïte, V., Indermühle, M., Engel, M., Cen, C., Mateos, J. M., et al. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-02-0112 · Cited by 148 · see citing works

Cellular communication in the circadian clock, the suprachiasmatic nucleus

van den Pol, A. N., & Dudek, F. E. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90128-3 · Cited by 146 · see citing works

The output of neuronotrophic and neurite-promoting agents from rat brain astroglial cells: a microculture method for screening potential regulatory molecules

Rudge, J. S., Manthorpe, M., & Varon, S. S. (1985) · Developmental Brain Research · doi:10.1016/0165-3806(85)90188-9 · Cited by 145 · see citing works

Glial patterns during early development of antennal lobes of Manduca sexta: A comparison between normal lobes and lobes deprived of antennal axons

Oland, L. A., & Tolbert, L. P. (1987) · The Journal of Comparative Neurology · doi:10.1002/cne.902550204 · Cited by 144 · see citing works

Lesion of the rat entorhinal cortex leads to a rapid microglial reaction in the dentate gyrus

Gehrmann, J., Schoen, S. W., & Kreutzberg, G. W. (1991) · Acta Neuropathologica · doi:10.1007/bf00293378 · Cited by 144 · see citing works

Astroglia from defined brain regions as studied with primary cultures

Hansson, E. (1988) · Progress in Neurobiology · doi:10.1016/0301-0082(88)90008-1 · Cited by 144 · see citing works

Stimulation of astroglial serotonin receptors produces culture media which regulates growth of serotonergic neurons

Whitaker‐Azmitia, P. M., & Azmitia, E. C. (1989) · Brain Research · doi:10.1016/0006-8993(89)90972-4 · Cited by 141 · see citing works

Blocking C3d+/GFAP+ A1 Astrocyte Conversion with Semaglutide Attenuates Blood-Brain Barrier Disruption in Mice after Ischemic Stroke

Zhang, Q., Liu, C., Shi, R., Zhou, S., Shan, H., Deng, L., Chen, T., Guo, Y., Zhang, Z., Yang, G., et al. (2022) · Aging and Disease · doi:10.14336/ad.2021.1029 · Cited by 138 · see citing works

Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells

Tang, X., Zhou, L., Biel, A., Marchetto, M. C., Muotri, A. R., Gage, F. H., & Chen, G. (2013) · Stem Cell Research · doi:10.1016/j.scr.2013.05.002 · Cited by 136 · see citing works

Neuronotrophic factors for mammalian brain neurons: Injury induction in neonatal, adult and aged rat brain

Whittemore, S. R., Nieto‐Sampedro, M., Needels, D. L., & Cotman, C. W. (1985) · Developmental Brain Research · doi:10.1016/0165-3806(85)90102-6 · Cited by 136 · see citing works

Pyruvate participation in the low molecular weight trophic activity for central nervous system neurons in glia-conditioned media

Selak, I., Skaper, S. D., & Varon, S. S. (1985) · Journal of Neuroscience · doi:10.1523/jneurosci.05-01-00023.1985 · Cited by 133 · see citing works

On the numbers of neurons on fields CA1 and CA3 of the hippocampus of Sprague-Dawley and Wistar rats

Boss, B. D., Turlejski, K., Stanfield, B. B., & Cowan, W. M. (1987) · Brain Research · doi:10.1016/0006-8993(87)90793-1 · Cited by 131 · see citing works

Roles of l-serine and sphingolipid synthesis in brain development and neuronal survival

Hirabayashi, Y., & Furuya, S. (2008) · Progress in Lipid Research · doi:10.1016/j.plipres.2008.01.003 · Cited by 130 · see citing works

Astrocyte Depletion Impairs Redox Homeostasis and Triggers Neuronal Loss in the Adult CNS

Schreiner, B., Romanelli, E., Liberski, P. P., Ingold‐Heppner, B., Sobottka, B., Hartwig, T., Chandrasekar, V., Johannssen, H. C., Zeilhofer, H. U., Aguzzi, A., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.07.051 · Cited by 129 · see citing works

A neurotrophic factor (NTF) released from primary glial cultures supports survival and fiber outgrowth of cultured hippocampal neurons

Müller, H. W., & Seifert, W. E. (1982) · Journal of Neuroscience Research · doi:10.1002/jnr.490080209 · Cited by 179 · see citing works

The output of neuronotrophic and neurite-promoting agents from rat brain astroglial cells: a microculture method for screening potential regulatory molecules

Rudge, J. S., Manthorpe, M., & Varon, S. S. (1985) · Developmental Brain Research · doi:10.1016/0165-3806(85)90188-9 · Cited by 145 · see citing works

Interactions of astroglia derived factors with hippocampal neurons

Matthiessen, H. P., Schmalenbach, C., & Müller, H. W. (1987) · Journal of Neuroimmunology · doi:10.1016/0165-5728(87)90311-0

A Neuron-Astrocyte Co-Culture System to Investigate Astrocyte-Secreted Factors in Mouse Neuronal Development

Jones, E. V., Cook, D., & Murai, K. K. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-452-0_22 · Cited by 60 · see citing works

Divergent Trophic Actions of Glioma Conditioned Media on Cultured Rat Hippocampal Neurons.

Okuda, S., Saitō, H., & Katsuki, H. (1994) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.17.735 · Cited by 3 · see citing works