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Arctic-adapted dogs emerged at the Pleistocene–Holocene transition
Open accessAbstract
Sled dog arctic adaptations go far back: Dogs have been used for sledding in the Arctic as far back as ∼9500 years ago. However, the relationships among the earliest sled dogs, other dog populations, and wolves are unknown. Sinding et al. sequenced an ancient sled dog, 10 modern sled dogs, and an ancient wolf and analyzed their genetic relationships with other modern dogs. This analysis indicates that sled dogs represent an ancient lineage going back at least 9500 years and that wolves bred with the ancestors of sled dogs and precontact American dogs. However, gene flow between sled dogs and wolves likely stopped before ∼9500 years ago. Science , this issue p. 1495
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Large-scale population replacement occurred in dogs, wolves, horses, pigs and crops such as potato.
“Large-scale population replacement occurred in dogs 278 , wolves 196,279,280 , horses 148,281 , pigs 282 and crops such as potato 283 .”
From Ancient DNA analysis (2021) · cites this paper as [280]
Citation 278 is attached to the claim about dogs, not the other animals or potato. The paper’s discussion of genetic continuity in Arctic sled dogs and admixture in some sled dogs (indexed section labeled Abstract; page unavailable) does not establish large-scale population replacement in dogs. A search for replacement and for replacement of indigenous dogs found no passage in our copy that establishes that claim. (LLM, conf=0.72)
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Self-citation
Metadata
- Authors
- Sinding, M.-H. S., Gopalakrishnan, S., Ramos-Madrigal, J., de Manuel, M., Pitulko, V. V., Kuderna, L., Feuerborn, T. R., Frantz, L. A. F., Vieira, F. G., Niemann, J., Samaniego Castruita, J. A., Carøe, C., Andersen-Ranberg, E. U., Jordan, P. D., Pavlova, E. Y., Nikolskiy, P. A., Kasparov, A. K., Ivanova, V. V., Willerslev, E., Skoglund, P., Fredholm, M., Wennerberg, S. E., Heide-Jørgensen, M. P., Dietz, R., Sonne, C., Meldgaard, M., Dalén, L., Larson, G., Petersen, B., Sicheritz-Pontén, T., Bachmann, L., Wiig, Ø., Marques-Bonet, T., Hansen, A. J., & Gilbert, M. T. P.
- Affiliations
- University of Copenhagen (DK)
- The GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
- Consejo Superior de Investigaciones Científicas (ES)
- Institute for the History of Material Culture, Russian Academy of Sciences, St. Petersburg, Russia.
- Queen Mary University of London (GB)
- University of Groningen (NL)
- Arctic and Antarctic Research Institute (RU)
- Russian Academy of Sciences (RU)
- VNIIOkeangeologia Research Institute (The All-Russian Research Institute of Geology and Mineral Resources of the World Ocean), St. Petersburg, Russia.
- Harvard University (US)
- Greenland Government (GL)
- Greenland Institute of Natural Resources, Nuuk, Greenland.
- Department of Bioscience, Arctic Research Centre, Aarhus University, Roskilde, Denmark.
- Ilisimatusarfik (GL)
- Swedish Museum of Natural History (SE)
- University of Oxford (GB)
- University of Oslo (NO)
- Institute of Evolutionary Biology (UPF-CSIC), Barcelona, Spain.
- Corresponding author
- Sinding, Mikkel-Holger S.
- Gopalakrishnan, Shyam
- de Manuel, Marc
- Hansen, Anders J.
- Gilbert, M. Thomas P.
- ORCID
- Sinding, Mikkel-Holger S.
- Gopalakrishnan, Shyam
- Ramos-Madrigal, Jazmín
- de Manuel, Marc
- Pitulko, Vladimir V.
- Kuderna, Lukas
- Feuerborn, Tatiana R.
- Frantz, Laurent A. F.
- Vieira, Filipe G.
- Niemann, Jonas
- Carøe, Christian
- Andersen-Ranberg, Emilie U.
- Jordan, Peter D.
- Pavlova, Elena Y.
- Nikolskiy, Pavel A.
- Kasparov, Aleksei K.
- Ivanova, Varvara V.
- Willerslev, Eske
- Skoglund, Pontus
- Fredholm, Merete
- Wennerberg, Sanne Eline
- Heide-Jørgensen, Mads Peter
- Dietz, Rune
- Sonne, Christian
- Meldgaard, Morten
- Dalén, Love
- Larson, Greger
- Petersen, Bent
- Sicheritz-Pontén, Thomas
- Bachmann, Lutz
- Wiig, Øystein
- Marques-Bonet, Tomas
- Hansen, Anders J.
- Gilbert, M. Thomas P.
- Venue
- Science
- Published
- 2020-06-26
- Volume
- 368
- Issue
- 6498
- Pages
- 1495-1499
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- PMC
- PMC7116267
- OpenAlex
- W3037423625
- Cited by
- 103
- References
- 12
- Citations by year
- 2026: 16 · 2025: 14 · 2024: 19 · 2023: 12 · 2022: 18 · 2021: 18 · 2020: 6
- FWCI
- 11.04
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- other-oa
- Locations
- Science (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (publishedVersion, other-oa)
- University of Southern Denmark Research Portal (University of Southern Denmark) (publishedVersion, other-oa)
- PubMed (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion, other-oa)
- PubMed Central (acceptedVersion)
- Oxford University Research Archive (ORA) (University of Oxford) (acceptedVersion)
- Dipòsit Digital de Documents de la UAB (Universitat Autònoma de Barcelona) (submittedVersion, public-domain)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion)
- Scopus (Elsevier) (submittedVersion, cc-by)
- Queen Mary Research Online (Queen Mary University of London) (submittedVersion)
- Repositori digital de la UPF (Universitat Pompeu Fabra) (submittedVersion)
- NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
- Funders
- European Molecular Biology Organization (STF 8286)
- Wellcome (210119/Z/18/Z)
- Natural Environment Research Council (NE/S00078X/1)
- European Research Council (ERC-2015-CoG-681396–Extinction Genomics, ERC-2013-StG-337574-UNDEAD)
- Carlsbergfondet (CF14 - 0995)
- The Velux Foundations and Aage og Johanne Louis-Hansens Fond (The Qimmeq Project)
- European Union's Innovation Horizon 2020 (ArchSci2020 NO 676154)
- Rock Foundation of New York
- Ministerio de Economía y Competitividad (BES-2015-072143)
- Institut Nacional d'Educacio Fisica de Catalunya, Generalitat de Catalunya (FI_B01111)
- Obra Social "La Caixa" and Secretaria d’Universitats i Recerca and CERCA Programme del Departament d’Economia i Coneixement de la Generalitat de Catalunya (GRC 2017 SGR 880)
- Howard Hughes International Early Career
- MINECO/FEDER, UE (BFU2017-86471-P)
- Russian Science Foundation (N 16-18-10265-RNF)
- Marie Skłodowska-Curie actions (H2020 655732 - WhereWolf)
- Independent Research Fund Denmark (8028-00005B)
- Natural Environmental Research Council (NE/K005243/1 and NE/K003259/1)
- NHM Oslo
- Topics
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Human-Animal Interaction Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
- Keywords
- sled dogs, dog domestication, Arctic adaptation, Pleistocene-Holocene transition, gene flow
- MeSH terms
- Selective Breeding, Adaptation, Physiological, Animals, Apolipoproteins, Arctic Regions, Dogs, Fatty Acids, Greenland, Haplotypes, Siberia, Triglycerides, Genome, Sequence Analysis, DNA, Wolves, Mitochondrial Membrane Transport Proteins
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