Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans

Oude Munnink, Bas B.; Sikkema, Reina S.; Nieuwenhuijse, David F.; Molenaar, Robert Jan; Munger, Emmanuelle; Molenkamp, Richard; van der Spek, Arco; Tolsma, Paulien; Rietveld, Ariene; Brouwer, Miranda; Bouwmeester-Vincken, Noortje; Harders, Frank; Hakze-van der Honing, Renate; Wegdam-Blans, Marjolein C. A.; Bouwstra, Ruth J.; GeurtsvanKessel, Corine; van der Eijk, Annemiek A.; Velkers, Francisca C.; Smit, Lidwien A. M.; Stegeman, Arjan; van der Poel, Wim H. M.; Koopmans, Marion P. G.

doi:10.1126/science.abe5901

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Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans

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Oude Munnink, Bas B., Sikkema, Reina S., Nieuwenhuijse, David F., Molenaar, Robert Jan, Munger, Emmanuelle, Molenkamp, Richard, van der Spek, Arco, Tolsma, Paulien, Rietveld, Ariene, Brouwer, Miranda, Bouwmeester-Vincken, Noortje, Harders, Frank, Hakze-van der Honing, Renate, Wegdam-Blans, Marjolein C. A., Bouwstra, Ruth J., GeurtsvanKessel, Corine, van der Eijk, Annemiek A., Velkers, Francisca C., Smit, Lidwien A. M., Stegeman, Arjan, van der Poel, Wim H. M., Koopmans, Marion P. G.·2021·Science

DOI 10.1126/science.abe5901

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Abstract

Two-way transmission on mink farms: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a zoonotic virus—one that spilled over from another species to infect and transmit among humans. We know that humans can infect other animals with SARS-CoV-2, such as domestic cats and even tigers in zoos. Oude Munnink et al. used whole-genome sequencing to show that SARS-CoV-2 infections were rife among mink farms in the southeastern Netherlands, all of which are destined to be closed by March 2021 (see the Perspective by Zhou and Shi). Toward the end of June 2020, 68% of mink farm workers tested positive for the virus or had antibodies to SARS-CoV-2. These large clusters of infection were initiated by human COVID-19 cases with viruses that bear the D614G mutation. Sequencing has subsequently shown that mink-to-human transmission also occurred. More work must be done to understand whether there is a risk that mustelids may become a reservoir for SARS-CoV-2. Science , this issue p. 172 ; see also p. 120

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Authors: Oude Munnink, B. B., Sikkema, R. S., Nieuwenhuijse, D. F., Molenaar, R. J., Munger, E., Molenkamp, R., van der Spek, A., Tolsma, P., Rietveld, A., Brouwer, M., Bouwmeester-Vincken, N., Harders, F., Hakze-van der Honing, R., Wegdam-Blans, M. C. A., Bouwstra, R. J., GeurtsvanKessel, C., van der Eijk, A. A., Velkers, F. C., Smit, L. A. M., Stegeman, A., van der Poel, W. H. M., & Koopmans, M. P. G.
Venue: Science
Publisher: American Association for the Advancement of Science (AAAS)
Published: 2021-01-08
Volume: 371
Issue: 6525
Pages: 172-177
ISSN: 0036-8075 (ISSN-L)
1095-9203
DOI: 10.1126/science.abe5901
OpenAlex: W3102258632
Cited by: 1,117
References: 10
FWCI: 27.40
Type: journal article
Language: en
Open access: hybrid
Licence: creativecommons.org/licenses/by/4.0/ (vor)
Funders: ZonMW (10150062010005)
European Union’s Horizon 2020 research and innovation programme (848096, 101003589)
The European Union’s Horizon 2020 research and innovation programme (874735)
the Netherlands Ministry of Agriculture, Nature and Foods

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This page: CoChat. (2026). Citation check: Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans. https://app.cochat.ai/papers/10.1126/science.abe5901
The paper: Oude Munnink, B. B., Sikkema, R. S., Nieuwenhuijse, D. F., Molenaar, R. J., Munger, E., Molenkamp, R., van der Spek, A., Tolsma, P., Rietveld, A., Brouwer, M., Bouwmeester-Vincken, N., Harders, F., Hakze-van der Honing, R., Wegdam-Blans, M. C. A., Bouwstra, R. J., GeurtsvanKessel, C., van der Eijk, A. A., Velkers, F. C., Smit, L. A. M., . . . Koopmans, M. P. G. (2021). Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans. Science. https://doi.org/10.1126/science.abe5901

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Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans

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