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Twenty years of microplastic pollution research—what have we learned?
Open accessAbstract
Twenty years after the first publication that used the term microplastic, we review current understanding, refine definitions, and consider future prospects. Microplastics arise from multiple sources, including tires, textiles, cosmetics, paint, and the fragmentation of larger items. They are widely distributed throughout the natural environment, with evidence of harm at multiple levels of biological organization. They are pervasive in food and drink and have been detected throughout the human body, with emerging evidence of negative effects. Environmental contamination could double by 2040, and wide-scale harm has been predicted. Public concern is increasing, and diverse measures to address microplastic pollution are being considered in international negotiations. Clear evidence on the efficacy of potential solutions is now needed to address the issue and to minimize the risks of unintended consequences.
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Risk-based management framework for microplastics in aquatic ecosystems
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Self-citationPlastic debris and policy: Using current scientific understanding to invoke positive change
Rochman, C. M., Cook, A., & Koelmans, A. A. (2016) · Environmental Toxicology and Chemistry · doi:10.1002/etc.3408 · Cited by 152
Self-citationThe evolving global plastics policy landscape: An inventory and effectiveness review
Diana, Z., Vegh, T., Karasik, R., Bering, J., Caldas, J. D. L., Pickle, A., Rittschof, D., Lau, W. W. Y., & Virdin, J. (2022) · Environmental Science & Policy · doi:10.1016/j.envsci.2022.03.028 · Cited by 139
Hampton, L. M. T., Bouwmeester, H., Brander, S. M., Coffin, S., Cole, M., Hermabessière, L., Mehinto, A. C., Miller, E. L., Rochman, C. M., & Weisberg, S. B. (2022) · Microplastics and Nanoplastics · doi:10.1186/s43591-022-00038-y · Cited by 128
Marine litter keeps increasing
Ryan, P. G., & Moloney, C. L. (1993) · Nature · doi:10.1038/361023a0 · Cited by 127
On the Creation of Risk: Framing of Microplastics Risks in Science and Media
Völker, C., Kramm, J., & Wagner, M. (2019) · Global Challenges · doi:10.1002/gch2.201900010 · Cited by 127
Comparative study of three sampling methods for microplastics analysis in seawater
Zheng, Y., Li, J., Sun, C., Cao, W., Wang, M., Jiang, F., & Ju, P. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.144495 · Cited by 126
Swedish sources and pathways for microplastics to the marine environment
Magnusson, K., Eliaeson, K., Fråne, A., Haikonen, K., Olshammar, M., Stadmark, J., & Hultén, J. (2016) · Diva portal (Dalarna University Library) · Cited by 124
Davison, S. M. C., White, M. P., Pahl, S., Taylor, T., Fielding, K. S., Roberts, B. R., Economou, T., McMeel, O., Kellett, P., & Fleming, L. E. (2021) · Global Environmental Change · doi:10.1016/j.gloenvcha.2021.102309 · Cited by 117
Self-citationIngested microplastics: Do humans eat one credit card per week?
Pletz, M. (2022) · Journal of Hazardous Materials Letters · doi:10.1016/j.hazl.2022.100071 · Cited by 115
Global discharge of microplastics from mechanical recycling of plastic waste
Suzuki, G., Uchida, N., Tanaka, K., Higashi, O., Takahashi, Y., Kuramochi, H., Yamaguchi, N., & Osako, M. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.123855 · Cited by 113
New Evidence of Microplastics in the Lower Respiratory Tract: Inhalation through Smoking
Lu, W., Li, X., Wang, S., Tu, C., Qiu, L., Zhang, H., Zhong, C., Li, S., Liu, Y., Liu, J., et al. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.3c00716 · Cited by 111
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Micro(nano)plastics in the Human Body: Sources, Occurrences, Fates, and Health Risks
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Plastic Food Packaging from Five Countries Contains Endocrine- and Metabolism-Disrupting Chemicals
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Reducing plastic waste: A meta-analysis of influences on behaviour and interventions
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On the harmonization of methods for measuring the occurrence, fate and effects of microplastics
Rochman, C. M., Regan, F. B., & Thompson, R. C. (2017) · Analytical Methods · doi:10.1039/c7ay90014g · Cited by 81
Self-citationShafi, M., Lodh, A., Khajuria, M., Ranjan, V. P., Gani, K. M., Chowdhury, S., & Goel, S. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.133445 · Cited by 80
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Self-citationExplaining risk perception of microplastics: Results from a representative survey in Germany
Kramm, J., Steinhoff, S., Werschmöller, S., Völker, B., & Völker, C. (2022) · Global Environmental Change · doi:10.1016/j.gloenvcha.2022.102485 · Cited by 78
Armada, D., Llompart, M., Celeiro, M., Garcia-Castro, P., Ratola, N., Dagnac, T., & de Boer, J. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.152542 · Cited by 74
Risk Perception of Plastic Pollution: Importance of Stakeholder Involvement and Citizen Science
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Fontes, B. L. M., Souza, L. C. D. S. E., de Oliveira, A. P. S. D. S., da Fonseca, R. N., Neto, M. P. C., & Pinheiro, C. R. (2024) · Journal of Toxicology and Environmental Health Part B · doi:10.1080/10937404.2024.2330962 · Cited by 61
Weight of Evidence for the Microplastic Vector Effect in the Context of Chemical Risk Assessment
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Self-citationBiodegradability of Plastics in the Open Environment
(SAPEA), S. A. F. P. B. E. A. (2022) · Climate Change and Law Collection · doi:10.1163/9789004322714_cclc_2020-0189-1063 · Cited by 59
Nano- and microplastic PBK modeling in the context of human exposure and risk assessment
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Self-citationMetal-doping of nanoplastics enables accurate assessment of uptake and effects on Gammarus pulex
Redondo‐Hasselerharm, P. E., Vink, G. J., Mitrano, D. M., & Koelmans, A. A. (2021) · Environmental Science Nano · doi:10.1039/d1en00068c · Cited by 57
Self-citationCommunicating the absence of evidence for microplastics risk: Balancing sensation and reflection
Wardman, T., Koelmans, A. A., Whyte, J., & Pahl, S. (2020) · Environment International · doi:10.1016/j.envint.2020.106116 · Cited by 50
Self-citationRisk characterization of microplastics in San Francisco Bay, California
Coffin, S., Weisberg, S. B., Rochman, C. M., Kooi, M., & Koelmans, A. A. (2022) · Microplastics and Nanoplastics · doi:10.1186/s43591-022-00037-z · Cited by 50
Self-citationDeep dive into the chronic toxicity of tyre particle mixtures and their leachates
Boisseaux, P., Rauert, C., Dewapriya, P., Delignette‐Muller, M. L., Barrett, R., Durndell, L. J., Pohl, F., Thompson, R. C., Thomas, K. V., & Galloway, T. S. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.133580 · Cited by 50
Self-citationMiller, J. V., Maskrey, J. R., Chan, K., & Unice, K. M. (2021) · Analytical Letters · doi:10.1080/00032719.2021.1979994 · Cited by 49
Should we worry about the accumulation of microplastics in human organs?
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Falco, F. D., Nacci, T., Durndell, L. J., Thompson, R. C., Degano, I., & Modugno, F. (2023) · Journal of Analytical and Applied Pyrolysis · doi:10.1016/j.jaap.2023.105937 · Cited by 46
Self-citationBaechler, B. R., Frond, H. D., Dropkin, L., Leonard, G. H., Proano, L., & Mallos, N. J. (2024) · Frontiers in Marine Science · doi:10.3389/fmars.2023.1323477 · Cited by 46
Keep Plastics on a Tight Leash: Swedish Public Opinion on Plastic Policies
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Parker-Jurd, F. N. F., Smith, N. S., Gibson, L., Nuojua, S., & Thompson, R. C. (2022) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2022.114199 · Cited by 35
Self-citationFelipe-Rodriguez, M., Böhm, G., & Doran, R. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.920454 · Cited by 35
de Ruijter, V. N., Hof, M., Kotorou, P., van Leeuwen, J., van den Heuvel-Greve, M. J., Roessink, I., & Koelmans, A. A. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.3c06829 · Cited by 32
Self-citationExploring expert perceptions about microplastics: from sources to potential solutions
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Self-citationJanzik, R., Koch, S., Zamariola, G., Vrbos, D., White, M. P., Pahl, S., & Berger, N. (2023) · Risk Analysis · doi:10.1111/risa.14184 · Cited by 28
Self-citationRedondo‐Hasselerharm, P. E., Rico, A., Lwanga, E. H., van Gestel, C. A. M., & Koelmans, A. A. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.133732 · Cited by 27
Self-citationEckert, S., Karassin, O., & Steinebach, Y. (2024) · Environmental Policy and Governance · doi:10.1002/eet.2092 · Cited by 25
Addressing cultural context is the missing piece in policy solutions to plastic pollution
Willis, K. A., van Putten, I. E., & Hardesty, B. D. (2024) · Environmental Science & Policy · doi:10.1016/j.envsci.2024.103829 · Cited by 24
Dijk, J. V., Figuière, R., Dekker, S. C., van Wezel, A. P., & Cousins, I. T. (2023) · Environmental Science Processes & Impacts · doi:10.1039/d3em00025g · Cited by 22
Global criteria to address problematic, unnecessary and avoidable plastic products
Raubenheimer, K., & Urho, N. (2024) · TemaNord · doi:10.6027/temanord2024-508 · Cited by 18
Self-citationPlastics treaty — research must inform action
Thompson, R. C., Pahl, S., & Sembiring, E. (2022) · Nature · doi:10.1038/d41586-022-02201-0 · Cited by 16
Self-citationClark, N. J., Fischer, A. C., Durndell, L. J., Galloway, T. S., & Thompson, R. C. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2023.140058 · Cited by 14
Self-citationInfluence of psychological factors in food risk assessment – A review
Jenkins, S. C., Harris, A. J. L., & Osman, M. (2020) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2020.07.010 · Cited by 13
Nuojua, S., Cracknell, D., Heske, A., Pahl, S., Wyles, K. J., & Thompson, R. C. (2024) · Conservation Science and Practice · doi:10.1111/csp2.13174 · Cited by 13
Self-citationPlastic Pollution LitigationPreprint
Morath, S. J., Thompson, A. B., & Hamilton, S. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3919319 · Cited by 5
Flagged first, then by citations
Research works printed but not linked: 18
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- 10.1021/acs.est.7b03331 · DOI
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- 10.1098/rstb.2008.0284 · DOI · Paper page
- 10.1016/j.jhazmat.2024.133732 · DOI
- 10.1016/j.scitotenv.2020.144481 · DOI
- 10.1016/j.scitotenv.2020.144481 · DOI
- 10.1186/s43591-022-00040-4 · DOI · Paper page
- 10.1186/s43591-022-00040-4 · DOI · Paper page
- GESAMP Proceedings of the GESAMP International Workshop on Assessing the Risks Associated with Plastics and Microplastics in the Marine Environment P. J. Kershaw B. Carney Almroth P. Villarrubia-Gómez A. A. Koelmans T. Gouin Eds. (Reports and Studies 103 UNEP 2020).
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The distribution of subsurface microplastics in the ocean
Zhao, S., Kvale, K., Zhu, L., Zettler, E., Egger, M., Mincer, T. J., Amaral‐Zettler, L., Lebreton, L., Niemann, H., Nakajima, R., et al. (2025) · Nature · doi:10.1038/s41586-025-08818-1 · Cited by 357
Imperfect wound healing sets the stage for chronic diseases
Martin, P. B., Pardo-Pastor, C., Jenkins, G. R., & Rosenblatt, J. (2024) · Science · doi:10.1126/science.adp2974 · Cited by 262
Health impacts of microplastic and nanoplastic exposure
Lamoree, M. H., van Boxel, J., Nardella, F., Houthuijs, K. J., Brandsma, S. H., Béen, F. M., & van Duursen, M. B. M. (2025) · Nature Medicine · doi:10.1038/s41591-025-03902-5 · Cited by 243
The Lancet Countdown on health and plastics
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Zhao, Q., Fang, Z., Wang, P., Qian, Z., Yang, Y., Ran, L., Zheng, J., Tang, Y., Cui, X., Li, Y., et al. (2025) · ACS Nano · doi:10.1021/acsnano.4c15112 · Cited by 116
Metadata
- Authors
- Thompson, R. C., Courtene-Jones, W., Boucher, J., Pahl, S., Raubenheimer, K., & Koelmans, A. A.
- Affiliations
- University of Plymouth (GB)
- School of Biological and Marine Sciences, University of Plymouth, Plymouth, UK.
- EA–Earth Action, CH 1004 Lausanne, Switzerland.
- University of Vienna (AT)
- University of Wollongong (AU)
- Wageningen University & Research (NL)
- Corresponding author
- Thompson, Richard C.
- ORCID
- Venue
- Science
- Published
- 2024-10-25
- Volume
- 386
- Issue
- 6720
- Pages
- eadl2746-eadl2746
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W4402625926
- Cited by
- 1,521
- References
- 145
- Citations by year
- 2026: 829 · 2025: 647 · 2024: 45
- FWCI
- 39.21
- Type
- journal article
- Language
- en
- Open access
- green
- research.wur.nl
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Socio-Environmental Systems Modeling (submittedVersion)
- PEARL (University of Plymouth) (submittedVersion)
- Funders
- Natural Environment Research Council (NE/V00185X/1, NE/V007556/1, NE/S003967/1)
- Topics
- Physical Sciences › Environmental Science › Pollution › Microplastics and Plastic Pollution
- Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
- Keywords
- microplastics, microplastic pollution, microplastic sources, microplastic fragmentation, microplastic toxicity, human exposure to microplastics, plastic pollution mitigation
- MeSH terms
- Microplastics, Environmental Monitoring, Environmental Pollution, Humans
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