Cited by 162T-cell and B-cell ImmunologyHematopoietic Stem Cell TransplantationImmunotherapy and Immune Responses

Long-term maintenance of human naive T cells through in situ homeostasis in lymphoid tissue sites

Open access
Thome, Joseph J. C., Grinshpun, Boris, Kumar, Brahma V., Kubota, Masaru, Ohmura, Yoshiaki, Lerner, Harvey, Sempowski, Gregory D., Shen, Yufeng +1 more·2016·Science Immunology

Abstract

Human naïve T cells are maintained in lymph nodes for decades and clonally expand in situ after cessation of thymopoiesis.

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Integrity signals

Registry

Crossref · 10.1126/sciimmunol.aah6506

Cites

51 of 51 references verified0 citation errors · 0 not checkable

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Claims other papers make about this one

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  • Compartmentalization of naive and memory CD4+ and CD8+ T cells in spleen, lymph nodes, and blood changes over life.

    “compartmentalization of naive and memory CD4+ and CD8+ T cells in spleen, lymph nodes, and blood changes over life”

    From Successful and Maladaptive T Cell Aging (2017) · cites this paper as Thome et al., 2016

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Cites

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Research works printed but not linked: 1

  1. [52]Sims JS Grinshpun B Feng Y Ung TH Neira JA Samanamud JL Canoll P Shen Y Sims PA Bruce JN Diversity and divergence of the glioma-infiltrating T-cell receptor repertoire Proc Natl Acad Sci U S A 2016 PMC4922177 27261081

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Authors
Thome, J. J. C., Grinshpun, B., Kumar, B. V., Kubota, M., Ohmura, Y., Lerner, H., Sempowski, G. D., Shen, Y., & Farber, D. L.
Affiliations
  • Columbia University Irving Medical Center (US)
  • LiveOnNY, New York, NY 10001, USA.
  • Duke University (US)
  • Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY 10032, USA.
Corresponding author
  • Thome, Joseph J. C.
  • Grinshpun, Boris
Venue
Science Immunology
Published
2016-12-23
Volume
1
Issue
6
ISSN
2470-9468 (ISSN-L)
OpenAlex
W2560349103
Cited by
162
References
51
Citations by year
2026: 13 · 2025: 19 · 2024: 10 · 2023: 10 · 2022: 18 · 2021: 25 · 2020: 22 · 2019: 18 · 2018: 14 · 2017: 13
FWCI
9.02
Type
journal article
Language
en
Open access
Locations
  • Science Immunology (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institute on Aging (F31AG047003)
  • National Institute of General Medical Sciences (T32GM007367)
  • National Institute of Allergy and Infectious Diseases (U01AI100119, P01AI106697, R01AI100119, UC6AI058607)
  • National Center for Research Resources (S10RR027050)
Topics
  • Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
  • Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
  • Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
Keywords
naive T cells, T cell homeostasis, lymph nodes, thymopoiesis, lymphoid tissue

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