Cited by 265Prosthetics and Rehabilitation RoboticsNeuroscience and Neural EngineeringMuscle activation and electromyography studies

Enhancing functional abilities and cognitive integration of the lower limb prosthesis

Open access
Petrini, Francesco Maria, Valle, Giacomo, Bumbasirevic, Marko, Barberi, Federica, Bortolotti, Dario, Cvancara, Paul, Hiairrassary, Arthur, Mijovic, Pavle +12 more·2019·Science Translational Medicine

Abstract

Recreated missing leg sensations, connected to the prosthesis sensors, restored leg functional abilities and promoted its cognitive integration.

Integrity signals

Registry

Crossref · 10.1126/scitranslmed.aav8939

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55 of 55 references verified0 citation errors · 0 not checkable

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  • A recent trial documented that TIME electrodes improve functional abilities, cognitive ease in dual-tasks, and prosthesis embodiment in lower limb amputees.

    “In regard to lower limb amputees, a recent trial has documented the qualification of TIME electrodes in improving functional abilities, cognitive ease in dual-tasks, and prosthesis embodiment [102].”

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Authors
Petrini, F. M., Valle, G., Bumbasirevic, M., Barberi, F., Bortolotti, D., Cvancara, P., Hiairrassary, A., Mijovic, P., Sverrisson, A. Ö., Pedrocchi, A., Divoux, J.-L., Popovic, I., Lechler, K., Mijovic, B., Guiraud, D., Stieglitz, T., Alexandersson, A., Micera, S., Lesic, A., & Raspopovic, S.
Affiliations
  • ETH Zurich (CH)
  • Scuola Superiore Sant'Anna (IT)
  • Orthopaedic Surgery Department, School of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
  • Politecnico di Milano (IT)
  • Laboratory for Biomedical Microtechnology, Department of Microsystems Engineering, University of Freiburg—IMTEK, 79110 Freiburg, Germany.
  • Institut national de recherche en sciences et technologies du numérique (FR)
  • mBrainTrain d.o.o., 11000 Belgrade, Serbia.
  • Össur (Iceland) (IS)
  • Axonic, 06220 Vallauris, France.
  • Specialized hospital for rehabilitation and orthopaedic prosthetics, 11000 Belgrade, Serbia.
  • University of Freiburg (DE)
  • Össur hf., R&D, 110 Reykjavik, Iceland.
  • Laboratory for Neuroengineering, Department of Health Sciences and Technology, Institute for Robotics and Intelligent Systems, ETH Zürich, 8092 Zürich, Switzerland.
Corresponding author
  • Petrini, Francesco Maria
  • Valle, Giacomo
  • Micera, Silvestro
Venue
Science Translational Medicine
Published
2019-10-02
Volume
11
Issue
512
Pages
eaav8939
ISSN
  • 1946-6234 (ISSN-L)
  • 1946-6242
OpenAlex
W2977579781
Cited by
265
References
56
Citations by year
2026: 18 · 2025: 32 · 2024: 28 · 2023: 35 · 2022: 29 · 2021: 76 · 2020: 42 · 2019: 5
FWCI
13.41
Type
journal article
Language
en
Open access
Licence
cc-by-nc-nd
Locations
  • Science Translational Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion)
  • Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion, cc-by-nc-nd)
  • Virtual Community of Pathological Anatomy (University of Castilla La Mancha) (submittedVersion)
  • CINECA IRIS Institutional Research Information System (Sant'Anna School of Advanced Studies) (submittedVersion)
  • Repository for Publications and Research Data (ETH Zurich) (submittedVersion, other-oa)
  • ETH Zürich Research Collection
Funders
  • H2020 European Research Council (759998)
  • H2020 Future and Emerging Technologies (754497)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Prosthetics and Rehabilitation Robotics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
  • Physical Sciences › Engineering › Biomedical Engineering › Muscle activation and electromyography studies
Keywords
lower limb prosthesis, transfemoral amputation, sensory feedback, neurostimulation, neural prostheses, proprioception, tactile feedback, embodiment, cognitive effort, dual-task performance, fall prevention, mobility (physical function)
MeSH terms
Activities of Daily Living, Amputees, Artificial Limbs, Cognition, Humans, Knee Joint, Prosthesis Design, Lower Extremity

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