Cited by 484Antifungal resistance and susceptibilityBacterial Identification and Susceptibility TestingYeasts and Rust Fungi Studies

The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.

Progress in Antifungal Susceptibility Testing of Candida spp. by Use of Clinical and Laboratory Standards Institute Broth Microdilution Methods, 2010 to 2012

Open access

Pfaller, M. A., Diekema, D. J.·2012·Journal of Clinical Microbiology

DOI 10.1128/jcm.00937-12PMC PMC3421803

Open this paper in CoChat — free account Open PDF

Abstract

Antifungal susceptibility testing of Candida has been standardized and refined and now may play a useful role in managing Candida infections. Important new developments include validation of 24-h reading times for all antifungal agents and the establishment of species-specific epidemiological cutoff values (ECVs) for the systemically active antifungal agents and both common and uncommon species of Candida . The clinical breakpoints (CBPs) for fluconazole, voriconazole, and the echinocandins have been revised to provide species-specific interpretive criteria for the six most common species. The revised CBPs not only are predictive of clinical outcome but also provide a more sensitive means of identifying those strains with acquired or mutational resistance mechanisms. This brief review serves as an update on the new developments in the antifungal susceptibility testing of Candida spp. using Clinical and Laboratory Standards Institute (CLSI) broth microdilution (BMD) methods.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1128/jcm.00937-12

Cites

105 of 105 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Clinical Practice Guidelines for the Management Candidiasis: 2009 Update by the Infectious Diseases Society of America
Pappas, P. G., Kauffman, C. A., Andes, D., Benjamin, D. K., Calandra, T. F., Edwards, J. E., Filler, S. G., Fisher, J. F., Kullberg, B.-J., Zeichner, L. O., et al. (2009) · Clinical Infectious Diseases · doi:10.1086/596757 · Cited by 3,191
Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance
Ghannoum, M. A., & Rice, L. B. (1999) · Clinical Microbiology Reviews · doi:10.1128/cmr.12.4.501 · Cited by 1,811
Comparison of Caspofungin and Amphotericin B for Invasive Candidiasis
Mora-Duarte, J., Betts, R., Rotstein, C., Colombo, A. L., Thompson-Moya, L., Smietana, J., Lupinacci, R., Sable, C., Kartsonis, N., & Perfect, J. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa021585 · Cited by 1,380
Clinical, Cellular, and Molecular Factors That Contribute to Antifungal Drug Resistance
White, T. C., Marr, K. A., & Bowden, R. A. (1998) · Clinical Microbiology Reviews · doi:10.1128/cmr.11.2.382 · Cited by 1,353
Delaying the Empiric Treatment of Candida Bloodstream Infection until Positive Blood Culture Results Are Obtained: a Potential Risk Factor for Hospital Mortality
Morrell, M., Fraser, V. J., & Kollef, M. H. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.9.3640-3645.2005 · Cited by 1,286
Time to initiation of fluconazole therapy impacts mortality in patients with candidemia: A multi-institutional study.
Garey, K. W., Rege, M., Pai, M. P., Mingo, D. E., Suda, K. J., Turpin, R. S., & Bearden, D. T. (2006) · Clinical Infectious Diseases · doi:10.1086/504810 · Cited by 1,171
A Randomized Trial Comparing Fluconazole with Amphotericin B for the Treatment of Candidemia in Patients without Neutropenia
Rex, J. H., Bennett, J. E., Sugar, A. M., Pappas, P. G., van der Horst, C. M., Edwards, J. E., Washburn, R. G., Scheld, W. M., Karchmer, A. W., Dine, A. P., et al. (1994) · New England Journal of Medicine · doi:10.1056/nejm199411173312001 · Cited by 1,039
Candida and candidiasis.
Calderone, R. (2012) · ASM Press eBooks · Cited by 912
Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment
Pfaller, M. A. (2012) · The American Journal of Medicine · doi:10.1016/j.amjmed.2011.11.001 · Cited by 903
Self-citation
Epidemiology of Invasive Mycoses in North America
Pfaller, M. A., & Diekema, D. J. (2010) · Critical Reviews in Microbiology · doi:10.3109/10408410903241444 · Cited by 901
Self-citation

Show all 105 references

Research works printed but not linked: 1

PfallerMA DiekemaDJ. 2007. Azole antifungal drug cross-resistance: mechanisms, epidemiology, and clinical significance. J. Invasive Fungal Infect. 1:74–92.

Sorted by citations

Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species
Whaley, S. G., Berkow, E. L., Rybak, J. M., Nishimoto, A. T., Barker, K. S., & Rogers, P. D. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.02173 · Cited by 900
The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection
Mazuski, J. E., Tessier, J. M., May, A. K., Sawyer, R. G., Nadler, E. P., Rosengart, M. R., Chang, P. K., O’Neill, P. J., Mollen, K. P., Huston, J. M., et al. (2017) · Surgical Infections · doi:10.1089/sur.2016.261 · Cited by 604
Changes in the epidemiological landscape of invasive candidiasis
Lamoth, F., Lockhart, S. R., Berkow, E. L., & Calandra, T. (2018) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkx444 · Cited by 547
Emerging Threats in Antifungal-Resistant Fungal Pathogens
Sanglard, D. (2016) · Frontiers in Medicine · doi:10.3389/fmed.2016.00011 · Cited by 435
Multidrug-resistant endemic clonal strain of Candida auris in India
Chowdhary, A., Anil Kumar, V., Sharma, C., Prakash, A., Agarwal, K., Babu, R., Dinesh, K. R., Karim, S., Singh, S. K., Hagen, F., et al. (2014) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-013-2027-1 · Cited by 373
Malassezia ecology, pathophysiology, and treatment
Theelen, B., Cafarchia, C., Gaitanis, G., Bassukas, I. D., Boekhout, T., & Dawson, T. L. (2017) · Medical Mycology · doi:10.1093/mmy/myx134 · Cited by 353
Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.
Healey, K. R., Zhao, Y., Perez, W. B., Lockhart, S. R., Sobel, J. D., Farmakiotis, D., Kontoyiannis, D. P., Sanglard, D., Taj-Aldeen, S. J., Alexander, B. D., et al. (2016) · Nature Communications · doi:10.1038/ncomms11128 · Cited by 276
Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia
Rosenberg, A., Ene, I. V., Bibi, M., Zakin, S., Segal, E. S., Ziv, N., Dahan, A. M., Colombo, A. L., Bennett, R. J., & Berman, J. (2018) · Nature Communications · doi:10.1038/s41467-018-04926-x · Cited by 270
“Studying growth dynamics and quantifying tolerance revealed that it is: (1) a subpopulation effect and the size of the subpopulation is stable; (2) due to slow growth in drug stress; (3) correlates with intracellular drug levels; (4) dependent upon stress response pathways, and (5) mechanistically distinct from resist…”
Background
Candida auris–Associated Candidemia, South Africa
Magobo, R. E., Corcoran, C., Seetharam, S., & Govender, N. P. (2014) · Emerging Infectious Diseases · doi:10.3201/eid2007.131765 · Cited by 259
Non- albicans Candida Infection: An Emerging Threat
Deorukhkar, S. C., Saini, S., & Mathew, S. K. (2014) · Interdisciplinary Perspectives on Infectious Diseases · doi:10.1155/2014/615958 · Cited by 251
Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris
Rhodes, J., Abdolrasouli, A., Farrer, R. A., Cuomo, C. A., Aanensen, D. M., Armstrong-James, D., Fisher, M. C., & Schelenz, S. (2018) · Emerging Microbes & Infections · doi:10.1038/s41426-018-0045-x · Cited by 246
Echinocandin and Triazole Antifungal Susceptibility Profiles for Clinical Opportunistic Yeast and Mold Isolates Collected from 2010 to 2011: Application of New CLSI Clinical Breakpoints and Epidemiological Cutoff Values for Characterization of Geographic and Temporal Trends of Antifungal Resistance
Pfaller, M. A., Messer, S. A., Woosley, L. N., Jones, R. N., & Castanheira, M. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.00308-13 · Cited by 237
Self-citation
Epidemiology, species distribution, antifungal susceptibility, and outcome of Candidemia across five sites in Italy and Spain
Bassetti, M., Merelli, M., Righi, E., Diaz-Martin, A., Rosello, E. M., Luzzati, R., Parra, A., Trecarichi, E. M., Sanguinetti, M., Posteraro, B., et al. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.01998-13 · Cited by 228
Age and Gender Affect the Composition of Fungal Population of the Human Gastrointestinal Tract
Strati, F., Paola, M. D., Stefanini, I., Albanese, D., Rizzetto, L., Lionetti, P., Calabrò, A., Jousson, O., Donati, C., Cavalieri, D., et al. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01227 · Cited by 230
Whole genome sequencing of emerging multidrug resistant Candida auris isolates in India demonstrates low genetic variation
Sharma, C., Kumar, N., Pandey, R., Meis, J. F., & Chowdhary, A. (2016) · New Microbes and New Infections · doi:10.1016/j.nmni.2016.07.003 · Cited by 202
Nosocomial Candidiasis: Antifungal Stewardship and the Importance of Rapid Diagnosis
Pfaller, M. A., & Castanheira, M. (2015) · Medical Mycology · doi:10.1093/mmy/myv076 · Cited by 166
Self-citation
Oropharyngeal candidiasis in hospitalised COVID‐19 patients from Iran: Species identification and antifungal susceptibility pattern
Salehi, M., Ahmadikia, K., Mahmoudi, S., Kalantari, S., Jamalimoghadamsiahkali, S., Izadi, A., Kord, M., Manshadi, S. A. D., Seifi, A., Ghiasvand, F., et al. (2020) · Mycoses · doi:10.1111/myc.13137 · Cited by 160
New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics
Geddes‐McAlister, J., & Shapiro, R. S. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13739 · Cited by 161
Virulence Factors Contributing to Pathogenicity of Candida tropicalis and Its Antifungal Susceptibility Profile
Deorukhkar, S. C., Saini, S., & Mathew, S. K. (2014) · International Journal of Microbiology · doi:10.1155/2014/456878 · Cited by 152
Drug resistance in eukaryotic microorganisms
Fairlamb, A. H., Gow, N. A. R., Matthews, K. R., & Waters, A. P. (2016) · Nature Microbiology · doi:10.1038/nmicrobiol.2016.92 · Cited by 153
Antimicrobial Susceptibility Testing of Antimicrobial Peptides to Better Predict Efficacy
Mercer, D. K., Torres, M. D. T., Duay, S. S., Lovie, E., Simpson, L. W., von Köckritz‐Blickwede, M., de la Fuente‐Núñez, C., O′Neil, D. A., & Angeles-Boza, A. M. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.00326 · Cited by 142
Antifungal Pharmacokinetics and Pharmacodynamics
Lepak, A. J., & Andes, D. R. (2015) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a019653 · Cited by 134
Molecular Identification and Antifungal Susceptibility of Yeast Isolates Causing Fungemia Collected in a Population-Based Study in Spain in 2010 and 2011
Guinea, J., Zaragoza, Ó., Escribano, P., Martín‐Mazuelos, E., Pemán, J., Sánchez, F., & Cuenca‐Estrella, M. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02155-13 · Cited by 129
Isavuconazole, micafungin, and 8 comparator antifungal agents' susceptibility profiles for common and uncommon opportunistic fungi collected in 2013: temporal analysis of antifungal drug resistance using CLSI species-specific clinical breakpoints and proposed epidemiological cutoff values
Pfaller, M. A., Rhomberg, P. R., Messer, S. A., Jones, R. N., & Castanheira, M. (2015) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2015.04.008 · Cited by 127
Self-citation
Rapid antifungal susceptibility testing by matrix-assisted laser desorption ionization-time of flight mass spectrometry analysis.
Vella, A., De Carolis, E., Vaccaro, L., Posteraro, P., Perlin, D. S., Kostrzewa, M., Posteraro, B., & Sanguinetti, M. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.00903-13 · Cited by 124
Candida parapsilosis Resistance to Fluconazole: Molecular Mechanisms and In Vivo Impact in Infected Galleria mellonella Larvae
Souza, A. C. R., Fuchs, B. B., Pinhati, H. M. S., Siqueira, R. A., Hagen, F., Meis, J. F., Mylonakis, E., & Colombo, A. L. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01177-15 · Cited by 121
Current status of antifungal resistance and its impact on clinical practice
Alcázar‐Fuoli, L., & Mellado, E. (2014) · British Journal of Haematology · doi:10.1111/bjh.12896 · Cited by 118
Is the emergence of fungal resistance to medical triazoles related to their use in the agroecosystems? A mini review
Ribas, A. D. R. E., Spolti, P., Ponte, E. M. D., Donato, K. Z., Schrekker, H. S., & Fuentefría, A. M. (2016) · Brazilian Journal of Microbiology · doi:10.1016/j.bjm.2016.06.006 · Cited by 111
First Report of Candidemia Clonal Outbreak Caused by Emerging Fluconazole-Resistant Candida parapsilosis Isolates Harboring Y132F and/or Y132F+K143R in Turkey
Arastehfar, A. A., Daneshnia, F., Polat, S. H., Fang, W., Yaşar, M., Polat, F., Metin, D. Y., Rigole, P., Coenye, T., İlkit, M., et al. (2020) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01001-20 · Cited by 112
Caspofungin MICs correlate with treatment outcomes among patients with Candida glabrata invasive candidiasis and prior echinocandin exposure.
Shields, R. K., Nguyen, M. H., Press, E. G., Updike, C. L., & Clancy, C. J. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00136-13 · Cited by 105
Multilaboratory study of epidemiological cutoff values for detection of resistance in eight Candida species to fluconazole, posaconazole, and voriconazole
Espinel-Ingroff, A., Pfaller, M. A., Bustamante, B., Canton, E., Fothergill, A., Fuller, J., Gonzalez, G. M., Lass-Flörl, C., Lockhart, S. R., Martin-Mazuelos, E., et al. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02615-13 · Cited by 105
Self-citation
Antifungal susceptibility, genotyping, resistance mechanism, and clinical profile of Candida tropicalis blood isolates
Arastehfar, A. A., Daneshnia, F., Hafez, A. I., Khodavaisy, S., Najafzadeh, M. J., Charsizadeh, A., Zarrinfar, H., Salehi, M., Shahrabadi, Z. Z., Sasani, E., et al. (2019) · Medical Mycology · doi:10.1093/mmy/myz124 · Cited by 100
Epidemiology, clinical characteristics, and outcome of candidemia in a tertiary referral center in Italy from 2010 to 2014
The Candidemia Study Group, Barchiesi, F., Orsetti, E., Gesuita, R., Skrami, E., & Manso, E. (2015) · Infection · doi:10.1007/s15010-015-0845-z · Cited by 100
Nationwide Study of Candidemia, Antifungal Use, and Antifungal Drug Resistance in Iceland, 2000 to 2011
Ásmundsdóttir, L. R., Erlendsdóttir, H., & Gottfreðsson, M. (2012) · Journal of Clinical Microbiology · doi:10.1128/jcm.02566-12 · Cited by 99
Emergence of non-Candida albicans species: Epidemiology, phylogeny and fluconazole susceptibility profile
Sadeghi, G., Ebrahimi-Rad, M., Mousavi, S. F., Shams-Ghahfarokhi, M., & Razzaghi-Abyaneh, M. (2018) · Journal de Mycologie Médicale · doi:10.1016/j.mycmed.2017.12.008 · Cited by 96
UncommonCandidaSpecies Fungemia among Cancer Patients, Houston, Texas, USA
Jung, D. S., Farmakiotis, D., Jiang, Y., Tarrand, J. J., & Kontoyiannis, D. P. (2015) · Emerging infectious diseases · doi:10.3201/eid2111.150404 · Cited by 96
Advances in Identification of Clinical Yeast Isolates by Use of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
Buchan, B. W., & Ledeboer, N. A. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.03105-12 · Cited by 95
Regional data analysis of Candida non‐albicans strains collected in United States medical sites over a 6‐year period, 2006–2011
Pfaller, M. A., Jones, R. N., & Castanheira, M. (2014) · Mycoses · doi:10.1111/myc.12206 · Cited by 91
Self-citation
Invasive candidiasis in intensive care units in China: a multicentre prospective observational study
Guo, F., Yang, Y., Kang, Y., Zang, B., Cui, W., Qin, B., Qin, Y., Fang, Q., Qin, T., Jiang, D., et al. (2013) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkt083 · Cited by 91
Synergistic Effect of Fluconazole and Calcium Channel Blockers against Resistant Candida albicans
Liu, S., Yue, L., Gu, W., Li, X., Zhang, L., & Sun, S. (2016) · PLOS ONE · doi:10.1371/journal.pone.0150859 · Cited by 87
Curcumin as a Promising Antibacterial Agent: Effects on Metabolism and Biofilm Formation inS. mutans
Li, B., Li, X., Lin, H., & Zhou, Y. N. (2018) · BioMed Research International · doi:10.1155/2018/4508709 · Cited by 86
Clonal Candidemia Outbreak by Candida parapsilosis Carrying Y132F in Turkey: Evolution of a Persisting Challenge
Arastehfar, A. A., Polat, S. H., Daneshnia, F., Pan, W., Hafez, A. I., Fang, W., Liao, W., Şahbudak-Bal, Z., Metin, D. Y., de Almeida, J. N., et al. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.676177 · Cited by 86
In Vitro Activities of Isavuconazole and Comparator Antifungal Agents Tested against a Global Collection of Opportunistic Yeasts and Molds
Pfaller, M. A., Messer, S. A., Rhomberg, P. R., Jones, R. N., & Castanheira, M. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.00863-13 · Cited by 85
Self-citation
Differential activity of the oral glucan synthase inhibitor SCY-078 against wild-type and echinocandin-resistant strains of Candida species
Pfaller, M. A., Messer, S. A., Rhomberg, P. R., Borroto-Esoda, K., & Castanheira, M. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00161-17 · Cited by 84
Self-citation
Antifungal Susceptibility Testing of Fusarium: A Practical Approach
Al‐Hatmi, A. M. S., Curfs-Breuker, I., de Hoog, S., Meis, J. F. G. M., & Verweij, P. E. (2017) · Journal of Fungi · doi:10.3390/jof3020019 · Cited by 84
Epidemiology of Candidemia and Antifungal Susceptibility in Invasive Candida Species in the Asia-Pacific Region
Wang, H., Xu, Y., & Hsueh, P. (2016) · Future Microbiology · doi:10.2217/fmb-2016-0099 · Cited by 84
ERG6 and ERG2 Are Major Targets Conferring Reduced Susceptibility to Amphotericin B in Clinical Candida glabrata Isolates in Kuwait
Ahmad, S., Joseph, L., Parker, J. E., Asadzadeh, M., Kelly, S. L., Meis, J. F. G. M., & Khan, Z. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01900-18 · Cited by 83
Comparison of EUCAST and CLSI broth microdilution methods for the susceptibility testing of 10 Systemically active antifungal agents when tested against Candida spp.
Pfaller, M. A., Castanheira, M., Messer, S. A., Rhomberg, P. R., & Jones, R. N. (2014) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2014.03.004 · Cited by 83
Self-citation
The ever-evolving landscape of candidaemia in patients with acute leukaemia: non-susceptibility to caspofungin and multidrug resistance are associated with increased mortality
Wang, E., Farmakiotis, D., Yang, D., McCue, D. A., Kantarjian, H. M., Kontoyiannis, D. P., & Mathisen, M. S. (2015) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkv087 · Cited by 82
Candidemia among Iranian Patients with Severe COVID-19 Admitted to ICUs
Arastehfar, A. A., Shaban, T., Zarrinfar, H., Roudbary, M., Ghazanfari, M., Hedayati, M. T., Sedaghat, A., İlkit, M., Najafzadeh, M. J., & Perlin, D. S. (2021) · Journal of Fungi · doi:10.3390/jof7040280 · Cited by 82
Candidemia in the elderly: What does it change?
Barchiesi, F., Orsetti, E., Mazzanti, S., Trave, F., Salvi, A., Nitti, C., & Manso, E. (2017) · PLoS ONE · doi:10.1371/journal.pone.0176576 · Cited by 81
Antifungal Susceptibility Testing: A Primer for Clinicians
Wiederhold, N. P. (2021) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofab444 · Cited by 81
Epidemiology, risk factor, species distribution, antifungal resistance and outcome of Candidemia at a single French hospital: a 7‐year study
Tadec, L., Talarmin, J., Gastinne, T., Bretonnière, C., Miegeville, M., Pape, P. L., & Morio, F. (2016) · Mycoses · doi:10.1111/myc.12470 · Cited by 79
Azole susceptibility ofMalassezia pachydermatisandMalassezia furfurand tentative epidemiological cut-off values
Cafarchia, C., Iatta, R., Immediato, D., Puttilli, M. R., & Otranto, D. (2015) · Medical Mycology · doi:10.1093/mmy/myv049 · Cited by 77
Use of Micafungin as a Surrogate Marker To Predict Susceptibility and Resistance to Caspofungin among 3,764 Clinical Isolates of Candida by Use of CLSI Methods and Interpretive Criteria
Pfaller, M. A., Messer, S. A., Diekema, D. J., Jones, R. N., & Castanheira, M. (2014) · Journal of Clinical Microbiology · doi:10.1128/jcm.02481-13 · Cited by 74
Self-citation
Antifungal Susceptibility Profiles of Bloodstream Yeast Isolates by Sensititre YeastOne over Nine Years at a Large Italian Teaching Hospital
Posteraro, B., Spanu, T., Fiori, B., Maio, F. D., Carolis, E. D., Giaquinto, A., Prete, V., Angelis, G. D., Torelli, R., D’Inzeo, T., et al. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00285-15 · Cited by 74
A multi-centric Study of Candida bloodstream infection in Lima-Callao, Peru: Species distribution, antifungal resistance and clinical outcomes
Rodriguez, L., Bustamante, B., Huaroto, L., Agurto, C., Illescas, R., Ramírez, R., Díaz, A., & Hidalgo, J. A. M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0175172 · Cited by 73
Curcumin-Loaded Liquid Crystalline Systems for Controlled Drug Release and Improved Treatment of Vulvovaginal Candidiasis
Rodero, C. F., Calixto, G. M. F., dos Santos, K. C., Sato, M. R., Ramos, M. A. D. S., Miró, M. S., Rodríguez, E., Vigezzi, C., Bauab, T. M., Sotomayor, C. E., et al. (2018) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.8b00507 · Cited by 72
Gut microbiota profiles and characterization of cultivable fungal isolates in IBS patients
Sciavilla, P., Strati, F., Paola, M. D., Modesto, M., Vitali, F., Cavalieri, D., Prati, G. M., Vito, M. D., Aragona, G., Filippo, C. D., et al. (2021) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-021-11264-4 · Cited by 72
Synergistic Effects of Amiodarone and Fluconazole on Candida tropicalis Resistant to Fluconazole
da Silva, C. R., Neto, J. B. D. A., Sidrim, J. J. C., Ângelo, M. R. F., Magalhães, H. I. F., Cavalcanti, B. C., Brilhante, R. S. N., Macêdo, D. S., de Moraes, M. O., Lobo, M. D. P., et al. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00966-12 · Cited by 71
Epidemiology, species distribution and outcome of nosocomial Candida spp.bloodstream infection in Shanghai
Yang, Z., Wu, L., Liu, X., Zhou, M., Li, J., Wu, J., Cai, Y., Mao, E., Chen, E., & Lortholary, O. (2014) · BMC Infectious Diseases · doi:10.1186/1471-2334-14-241 · Cited by 70
Antifungal Activity of Naphthoquinoidal Compounds In Vitro against Fluconazole-Resistant Strains of Different Candida Species: A Special Emphasis on Mechanisms of Action on Candida tropicalis
Neto, J. B. D. A., da Silva, C. R., Neta, M. A. S., Campos, R. D. S., Siebra, J. T., Silva, R. A. C., Gaspar, D. M., Magalhães, H. I. F., de Moraes, M. O., Lobo, M. D. P., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093698 · Cited by 69
Resistance Mechanisms and Clinical Features of Fluconazole-Nonsusceptible Candida tropicalis Isolates Compared with Fluconazole-Less-Susceptible Isolates
Choi, M. J., Won, E. J., Shin, J. H., Kim, S. H., Lee, W. G., Kim, M., Lee, K., Shin, M., Suh, S., Ryang, D. W., et al. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02652-15 · Cited by 72
Activity of a Long-Acting Echinocandin, Rezafungin, and Comparator Antifungal Agents Tested against Contemporary Invasive Fungal Isolates (SENTRY Program, 2016 to 2018)
Pfaller, M. A., Carvalhaes, C., Messer, S. A., Rhomberg, P. R., & Castanheira, M. (2020) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00099-20 · Cited by 68
Self-citation
In vitro activity of a Hos2 deacetylase inhibitor, MGCD290, in combination with echinocandins against echinocandin-resistant Candida species
Pfaller, M. A., Rhomberg, P. R., Messer, S. A., & Castanheira, M. (2015) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2014.11.008 · Cited by 67
Self-citation
Activity of echinocandins and triazoles against a contemporary (2012) worldwide collection of yeast and moulds collected from invasive infections
Castanheira, M., Messer, S. A., Jones, R. N., Farrell, D. J., & Pfaller, M. A. (2014) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2014.06.007 · Cited by 66
Self-citation
Invasive candidiasis in intensive care units in China: in vitro antifungal susceptibility in the China-SCAN study
Liu, W., Tan, J., Sun, J., Xu, Z., Li, M., Yang, Q., Shao, H., Zhang, L., Liu, W., Wan, Z., et al. (2013) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkt330 · Cited by 67
Candida tropicalis is the most prevalent yeast species causing candidemia in Algeria: the urgent need for antifungal stewardship and infection control measures
Megri, Y., Arastehfar, A. A., Boekhout, T., Daneshnia, F., Hörtnagl, C., Sartori, B., Hafez, A. I., Pan, W., Lass‐Flörl, C., & Hamrioui, B. (2020) · Antimicrobial Resistance and Infection Control · doi:10.1186/s13756-020-00710-z · Cited by 70
Changing trends in epidemiology and antifungal susceptibility patterns of six bloodstream Candida species isolates over a 12-year period in Kuwait
Khan, Z., Ahmad, S., Al‐Sweih, N., Mokaddas, E. M., Al-Banwan, K., Alfouzan, W. A., Al‐Obaid, I., Alobaid, K., Asadzadeh, M., Jeragh, A., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0216250 · Cited by 67
Retrospective analysis of mortality and Candida isolates of 75 patients with candidemia: a single hospital experience
Hirano, R., Sakamoto, Y., Kudo, K., & Ohnishi, M. (2015) · Infection and Drug Resistance · doi:10.2147/idr.s80677 · Cited by 65
CD101, a long-acting echinocandin, and comparator antifungal agents tested against a global collection of invasive fungal isolates in the SENTRY 2015 Antifungal Surveillance Program
Pfaller, M. A., Messer, S. A., Rhomberg, P. R., & Castanheira, M. (2017) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2017.03.028 · Cited by 65
Self-citation
Antifungal susceptibilities of Candida, Cryptococcus neoformans and Aspergillus fumigatus from the Asia and Western Pacific region: data from the SENTRY antifungal surveillance program (2010–2012)
Pfaller, M. A., Messer, S. A., Jones, R. N., & Castanheira, M. (2015) · The Journal of Antibiotics · doi:10.1038/ja.2015.29 · Cited by 64
Self-citation
Candida,Cryptococcus, and Other Yeasts of Medical Importance
Howell, S. A., Hazen, K. C., & Brandt, M. E. (2015) · ASM Press eBooks · doi:10.1128/9781555817381.ch117 · Cited by 62
In Vitro Activity of Isavuconazole against Opportunistic Fungal Pathogens from Two Mycology Reference Laboratories
Pfaller, M. A., Rhomberg, P. R., Wiederhold, N. P., Gibas, C. F. C., Sanders, C. J., Fan, H., Mele, J., Kovanda, L. L., & Castanheira, M. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01230-18 · Cited by 64
Self-citation
Screening the antifungal activities of monoterpenes and their isomers againstCandidaspecies
Iraji, A., Yazdanpanah, S., Alizadeh, F., Mirzamohammadi, S., Ghasemi, Y., Pakshir, K., Yang, Y., & Zomorodian, K. (2020) · Journal of Applied Microbiology · doi:10.1111/jam.14740 · Cited by 62
Factors related to outcome of bloodstream infections due to Candida parapsilosis complex
Barchiesi, F., Orsetti, E., Osimani, P., Catassi, C., Santelli, F., & Manso, E. (2016) · BMC Infectious Diseases · doi:10.1186/s12879-016-1704-y · Cited by 61
The Candida albicans ATO Gene Family Promotes Neutralization of the Macrophage Phagolysosome
Danhof, H. A., & Lorenz, M. C. (2015) · Infection and Immunity · doi:10.1128/iai.00984-15 · Cited by 62
Prevalence and antifungal susceptibility profiles of Candida glabrata, Candida parapsilosis and their close-related species in oral candidiasis
Miranda-Cadena, K., Marcos‐Arias, C., Mateo, E., Aguirre, J. M., Quindós, G., & Eraso, E. (2018) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2018.07.017 · Cited by 58
Oral colonization by Candida species in HIV-positive patients: association and antifungal susceptibility study
Goulart, L. S., de Souza, W. W. R., Vieira, C. A., de Lima, J. S., de Olinda, R. A., & de Araújo, C. (2018) · Einstein (São Paulo) · doi:10.1590/s1679-45082018ao4224 · Cited by 57
Rapid emergence of echinocandin resistance during Candida kefyr fungemia treatment with caspofungin
Fekkar, A., Meyer, I., Brossas, J. Y., Dannaoui, E., Palous, M., Uzunov, M., Nguyen, S., Leblond, V., Mazier, D., & Datry, A. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02037-12 · Cited by 56
Microbiologic and clinical characteristics of biofilm-forming Candida parapsilosis isolates associated with fungaemia and their impact on mortality
Soldini, S., Posteraro, B., Vella, A., Carolis, E. D., Borghi, E., Falleni, M., Losito, A. R., Maiuro, G., Trecarichi, E. M., Sanguinetti, M., et al. (2017) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2017.11.005 · Cited by 57
Antifungal susceptibility testing of Candida species isolated from the immunocompromised patients admitted to ten university hospitals in Iran: comparison of colonizing and infecting isolates
Badiee, P., Badali, H., Boekhout, T., Diba, K., Moghadam, A. G., Hosseininasab, A., Jafarian, H., Mohammadi, R., Mirhendi, H., Najafzadeh, M. J., et al. (2017) · BMC Infectious Diseases · doi:10.1186/s12879-017-2825-7 · Cited by 56
Susceptibility testing of fungi to antifungal drugs
Sanguinetti, M., & Posteraro, B. (2018) · Journal of Fungi · doi:10.3390/jof4030110 · Cited by 55
MDR1 overexpression combined with ERG11 mutations induce high-level fluconazole resistance in Candida tropicalis clinical isolates
Jin, L., Cao, Z., Wang, Q., Wang, Y., Wang, X., Chen, H., & Wang, H. (2018) · BMC Infectious Diseases · doi:10.1186/s12879-018-3082-0 · Cited by 55
Detection of triazole resistance among Candida species by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS)
Saraçlı, M. A., Fothergill, A. W., Sutton, D. A., & Wiederhold, N. P. (2015) · Medical Mycology · doi:10.1093/mmy/myv046 · Cited by 54
Core/shell (ZnO/polyacrylamide) nanocomposite: In-situ emulsion polymerization, corrosion inhibition, anti-microbial and anti-biofilm characteristics
Morsi, R. E., Labena, A., & Khamis, E. A. (2016) · Journal of the Taiwan Institute of Chemical Engineers · doi:10.1016/j.jtice.2016.03.037 · Cited by 54
Low Level of Antifungal Resistance in Iranian Isolates of Candida glabrata Recovered from Blood Samples in a Multicenter Study from 2015 to 2018 and Potential Prognostic Values of Genotyping and Sequencing of PDR1
Arastehfar, A. A., Daneshnia, F., Zomorodian, K., Najafzadeh, M. J., Khodavaisy, S., Zarrinfar, H., Hagen, F., Shahrabadi, Z. Z., Lackner, M., Mirhendi, H., et al. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02503-18 · Cited by 57
Iron Restriction to Clinical Isolates of Candida albicans by the Novel Chelator DIBI Inhibits Growth and Increases Sensitivity to Azoles In Vitro and In Vivo in a Murine Model of Experimental Vaginitis
Savage, K. A., Parquet, M. D. C., Allan, D. S., Davidson, R. J., Holbein, B. E., Lilly, E. A., & Fidel, P. L. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02576-17 · Cited by 53
Fruits as the vehicle of drug resistant pathogenic yeasts
Lo, H., Tsai, S.-H., Chu, W.-L., Chen, Y.-Z., Zhou, Z.-L., Chen, H.-F., Lee, C.-F., & Yang, Y.-L. (2017) · Journal of Infection · doi:10.1016/j.jinf.2017.06.005 · Cited by 53
RETRACTED: Sanguinarine Inhibits Mono- and Dual-Species Biofilm Formation by Candida albicans and Staphylococcus aureus and Induces Mature Hypha Transition of C. albicans
Qian, W., Wang, W., Zhang, J., Liu, M., Fu, Y., Li, X., Wang, T., & Li, Y. (2020) · Pharmaceuticals · doi:10.3390/ph13010013 · Cited by 52
Retracted
Quantitative Microplate-Based Growth Assay for Determination of Antifungal Susceptibility of Histoplasma capsulatum Yeasts
Goughenour, K. D., Balada-Llasat, J.-M., & Rappleye, C. A. (2015) · Journal of Clinical Microbiology · doi:10.1128/jcm.00795-15 · Cited by 55
Genetically related micafungin-resistant Candida parapsilosis blood isolates harbouring novel mutation R658G in hotspot 1 of Fks1p: a new challenge?
Arastehfar, A. A., Daneshnia, F., Polat, S. H., İlkit, M., Yaşar, M., Polat, F., Metin, D. Y., Dökümcü, Z., Pan, W., Hagen, F., et al. (2020) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkaa419 · Cited by 52
Clonality of Fluconazole-Nonsusceptible Candida tropicalis in Bloodstream Infections, Taiwan, 2011–2017
Chen, P.-Y., Chuang, Y.-C., Wu, U.-I., Sun, H.-Y., Wang, J.-T., Sheng, W.-H., Lo, H.-J., Wang, H.-Y., Chen, Y.-C., & Chang, S.-C. (2019) · Emerging Infectious Diseases · doi:10.3201/eid2509.190520 · Cited by 51
Use of Anidulafungin as a Surrogate Marker To Predict Susceptibility and Resistance to Caspofungin among 4,290 Clinical Isolates of Candida by Using CLSI Methods and Interpretive Criteria
Pfaller, M. A., Diekema, D. J., Jones, R. N., & Castanheira, M. (2014) · Journal of Clinical Microbiology · doi:10.1128/jcm.00782-14 · Cited by 51
Self-citation
Multicenter Study of Anidulafungin and Micafungin MIC Distributions and Epidemiological Cutoff Values for Eight Candida Species and the CLSI M27-A3 Broth Microdilution Method
Pfaller, M. A., Espinel‐Ingroff, A., Bustamante, B., Cantón, R., Diekema, D. J., Fothergill, A., Fuller, J., González, G. M., Guarro, J., Lass‐Flörl, C., et al. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02020-13 · Cited by 51
Self-citation
Spectrum of Opportunistic Fungal Infections in HIV/AIDS Patients in Tertiary Care Hospital in India
Kaur, R., Dhakad, M. S., Goyal, R., Bhalla, P., & Dewan, R. (2016) · Canadian Journal of Infectious Diseases and Medical Microbiology · doi:10.1155/2016/2373424 · Cited by 51
Multilocus Sequence Typing (MLST) Genotypes of Candida glabrata Bloodstream Isolates in Korea: Association With Antifungal Resistance, Mutations in Mismatch Repair Gene (Msh2), and Clinical Outcomes
Byun, S. A., Won, E. J., Kim, M., Lee, W. G., Lee, K., Lee, H. S., Uh, Y., Healey, K. R., Perlin, D. S., Choi, M. J., et al. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01523 · Cited by 51
CandidaBloodstream Infections in Italy: Changing Epidemiology during 16 Years of Surveillance
Caggiano, G., Coretti, C., Bartolomeo, N., Lovero, G., Giglio, O. D., & Montagna, M. T. (2015) · BioMed Research International · doi:10.1155/2015/256580 · Cited by 51
Culture-Independent Molecular Methods for Detection of Antifungal Resistance Mechanisms and Fungal Identification
Perlin, D. S., & Wiederhold, N. P. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix121 · Cited by 51
Milbemycins: More than Efflux Inhibitors for Fungal Pathogens
Silva, L. V., Sanguinetti, M., Vandeputte, P., Torelli, R., Rochat, B., & Sanglard, D. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02040-12 · Cited by 49

Authors: Pfaller, M. A., & Diekema, D. J.
Affiliations: University of Iowa (US)
ORCID: Pfaller, M. A.
Diekema, D. J.
Venue: Journal of Clinical Microbiology
Publisher: American Society for Microbiology
Published: 2012-09
Volume: 50
Issue: 9
Pages: 2846-2856
ISSN: 0095-1137 (ISSN-L)
1098-660X
DOI: 10.1128/jcm.00937-12
PMC: PMC3421803
OpenAlex: W2120299440
Cited by: 484
References: 105
Citations by year: 2026: 15 · 2025: 20 · 2024: 24 · 2023: 29 · 2022: 26 · 2021: 41 · 2020: 41 · 2019: 31 · 2018: 43 · 2017: 46 · 2016: 45 · 2015: 41 · 2014: 47 · 2013: 31 · 2012: 4
FWCI: 4.88
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Journal of Clinical Microbiology (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Pfizer
Eisai
Astellas Pharma
Topics: Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
Health Sciences › Medicine › Microbiology (medical) › Bacterial Identification and Susceptibility Testing
Life Sciences › Immunology and Microbiology › Microbiology › Yeasts and Rust Fungi Studies
Keywords: Candida, antifungal susceptibility testing, broth microdilution, epidemiological cut-off values, clinical breakpoints, fluconazole, voriconazole, echinocandins, antifungal resistance, Candida species, CLSI guidelines
MeSH terms: Antifungal Agents, Candida, Candidiasis, Humans, Microbial Sensitivity Tests

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Progress in Antifungal Susceptibility Testing of Candida spp. by Use of Clinical and Laboratory Standards Institute Broth Microdilution Methods, 2010 to 2012

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks