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Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies
Open accessAbstract
OBJECTIVE: To determine whether individual fruits are differentially associated with risk of type 2 diabetes. DESIGN: Prospective longitudinal cohort study. SETTING: Health professionals in the United States. PARTICIPANTS: 66,105 women from the Nurses' Health Study (1984-2008), 85,104 women from the Nurses' Health Study II (1991-2009), and 36,173 men from the Health Professionals Follow-up Study (1986-2008) who were free of major chronic diseases at baseline in these studies. MAIN OUTCOME MEASURE: Incident cases of type 2 diabetes, identified through self report and confirmed by supplementary questionnaires. RESULTS: During 3,464,641 person years of follow-up, 12,198 participants developed type 2 diabetes. After adjustment for personal, lifestyle, and dietary risk factors of diabetes, the pooled hazard ratio of type 2 diabetes for every three servings/week of total whole fruit consumption was 0.98 (95% confidence interval 0.97 [corrected] to 0.99). With mutual adjustment of individual fruits, the pooled hazard ratios of type 2 diabetes for every three servings/week were 0.74 (0.66 to 0.83) for blueberries, 0.88 (0.83 to 0.93) for grapes and raisins, 0.89 (0.79 to 1.01) for prunes, 0.93 (0.90 to 0.96) for apples and pears, 0.95 (0.91 to 0.98) for bananas, 0.95 (0.91 to 0.99) for grapefruit, 0.97 (0.92 to 1.02) for peaches, plums, and apricots, 0.99 (0.95 to 1.03) for oranges, 1.03 (0.96 to 1.10) for strawberries, and 1.10 (1.02 to 1.18) for cantaloupe. The pooled hazard ratio for the same increment in fruit juice consumption was 1.08 (1.05 to 1.11). The associations with risk of type 2 diabetes differed significantly among individual fruits (P<0.001 in all cohorts). CONCLUSION: Our findings suggest the presence of heterogeneity in the associations between individual fruit consumption and risk of type 2 diabetes. Greater consumption of specific whole fruits, particularly blueberries, grapes, and apples, is significantly associated with a lower risk of type 2 diabetes, whereas greater consumption of fruit juice is associated with a higher risk.
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“Ezetimibe or a PCSK9 inhibitor as add‐on to statin therapy is shown to reduce the incidence of CVD in patients with diabetes and hyper‐LDL‐cholesterolemia 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 (grade B: 88% agreement).”
From Japanese clinical practice guideline for diabetes 2019 (2020) · cites this paper as [29]
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Cites
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus* (2002) · Diabetes Care · doi:10.2337/diacare.25.2007.s5 · Cited by 10,325
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (1997) · Diabetes Care · doi:10.2337/diacare.20.7.1183 · Cited by 6,220
Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance.
National Diabetes Data Group (1979) · Diabetes · doi:10.2337/diab.28.12.1039 · Cited by 4,909
Resveratrol improves health and survival of mice on a high-calorie diet
Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature · doi:10.1038/nature05354 · Cited by 4,290
Alternative Dietary Indices Both Strongly Predict Risk of Chronic Disease
Chiuve, S. E., Fung, T. T., Rimm, E. B., Hu, F. B., McCullough, M. L., Wang, M., Stampfer, M. J., & Willett, W. C. (2012) · The Journal of Nutrition · doi:10.3945/jn.111.157222 · Cited by 1,951
Self-citationDietary Fiber, Glycemic Load, and Risk of Non—insulin-dependent Diabetes Mellitus in Women
Salmerón, J. (1997) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1997.03540300040031 · Cited by 1,804
Flavonoid intake and risk of chronic diseases
Knekt, P., Kumpulainen, J. T., Järvinen, R., Rissanen, H. A., Heliövaara, M., Reunanen, A., Hakulinen, T., & Aromaa, A. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.3.560 · Cited by 1,765
Dietary Fiber, Glycemic Load, and Risk of NIDDM in Men
Salmerón, J., Ascherio, A., Rimm, E. B., Colditz, G. A., Spiegelman, D., Jenkins, D. J., Stampfer, M. J., Wing, A. L., & Willett, W. C. (1997) · Diabetes Care · doi:10.2337/diacare.20.4.545 · Cited by 1,426
Self-citationTimmers, S., Konings, E., Bilet, L., Houtkooper, R. H., van de Weijer, T., Goossens, G. H., Hoeks, J., van der Krieken, S., Ryu, D., Kersten, S., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.10.002 · Cited by 1,320
USDA National Nutrient Database for Standard Reference, Release 22
(2018) · Cited by 1,284
Carbohydrates, dietary fiber, and incident type 2 diabetes in older women
Meyer, K. A., Kushi, L. H., Jacobs, D. R., Slavin, J., Sellers, T. A., & Folsom, A. R. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.4.921 · Cited by 1,271
Reproducibility and validity of dietary patterns assessed with a food-frequency questionnaire
Hu, F. B., Rimm, E., Smith-Warner, S. A., Feskanich, D., Stampfer, M. J., Ascherio, A., Sampson, L., & Willett, W. C. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.2.243 · Cited by 1,165
Self-citationPhysical activity and incidence of non-insulin-dependent diabetes mellitus in women
Manson, J. E., Stampfer, M. J., Colditz, G. A., Willett, W. C., Rosner, B., Hennekens, C. H., Speizer, F. E., Rimm, E. B., & Krolewski, A. S. (1991) · The Lancet · doi:10.1016/0140-6736(91)90664-b · Cited by 1,164
Self-citationHu, F. B., Stampfer, M. J., Rimm, E., Ascherio, A., Rosner, B. A., Spiegelman, D., & Willett, W. C. (1999) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009849 · Cited by 1,085
Self-citationFeskanich, D., Rimm, E. B., Giovannucci, E. L., Colditz, G. A., Stampfer, M. J., Litin, L. B., & Willett, W. C. (1993) · Journal of the American Dietetic Association · doi:10.1016/0002-8223(93)91754-e · Cited by 1,070
Self-citationBiological Activities of Polyphenols from Grapes
Xia, E.-Q., Deng, G.-F., Guo, Y.-J., & Li, H.-B. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11020622 · Cited by 1,063
Salvini, S., Hunter, D. J., SAMPSON, L., Stampfer, M. J., Colditz, G. A., ROSNER, B. A., & Willett, W. C. (1989) · International Journal of Epidemiology · doi:10.1093/ije/18.4.858 · Cited by 1,038
Self-citationReport of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
The Expert Committee On The Diagnosis And Classification Of Diabetes Mellitus (1998) · Diabetes Care · doi:10.2337/diacare.21.1.s5 · Cited by 904
Physical Activity and Television Watching in Relation to Risk for Type 2 Diabetes Mellitus in Men
Hu, F. B., Leitzmann, M. F., Stampfer, M. J., Colditz, G. A., Willett, W. C., & Rimm, E. B. (2001) · Archives of Internal Medicine · doi:10.1001/archinte.161.12.1542 · Cited by 828
Self-citationSchulze, M. B., Liu, S., Rimm, E. B., Manson, J. E., Willett, W. C., & Hu, F. B. (2004) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.2.348 · Cited by 773
Self-citationCarter, P., Gray, L. J., Troughton, J., Khunti, K., & Davies, M. J. (2010) · BMJ · doi:10.1136/bmj.c4229 · Cited by 728
Depletion and disruption of dietary fibre. Effects on satiety, plasma-glucose, and serum-insulin.
Haber, G., Heaton, K. W., Murphy, D., & Burroughs, L. F. (1977) · The Lancet · doi:10.1016/s0140-6736(77)90494-9 · Cited by 638
Dietary Fat and Meat Intake in Relation to Risk of Type 2 Diabetes in Men
van Dam, R. M., Willett, W. C., Rimm, E. B., Stampfer, M. J., & Hu, F. B. (2002) · Diabetes Care · doi:10.2337/diacare.25.3.417 · Cited by 593
Self-citationMajor Dietary Protein Sources and Risk of Coronary Heart Disease in Women
Bernstein, A. M., Sun, Q., Hu, F. B., Stampfer, M. J., Manson, J. E., & Willett, W. C. (2010) · Circulation · doi:10.1161/circulationaha.109.915165 · Cited by 573
Self-citationTest of the National Death Index and Equifax Nationwide Death Search
Rich-Edwards, J. W., Corsano, K. A., & Stampfer, M. J. (1994) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a117191 · Cited by 530
Dietary flavonoid intakes and risk of type 2 diabetes in US men and women
Wedick, N. M., Pan, A., Cassidy, A., Rimm, E. B., Sampson, L., ROSNER, B. A., Willett, W. C., Hu, F. B., Sun, Q., & van Dam, R. M. (2012) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.028894 · Cited by 527
Self-citationDietary Patterns, Meat Intake, and the Risk of Type 2 Diabetes in Women
Fung, T. T., Schulze, M. B., Manson, J. E., Willett, W. C., & Hu, F. B. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.20.2235 · Cited by 492
Self-citationCoffee, Decaffeinated Coffee, and Tea Consumption in Relation to Incident Type 2 Diabetes Mellitus
Huxley, R. (2009) · Archives of Internal Medicine · doi:10.1001/archinternmed.2009.439 · Cited by 476
High-Dose Resveratrol Supplementation in Obese Men
Poulsen, M. M., Vestergaard, P. F., Clasen, B. F., Radko, Y., Christensen, L. P., Stødkilde-Jørgensen, H., Møller, N., Jessen, N., Pedersen, S. B., & Jørgensen, J. O. L. (2013) · Diabetes · doi:10.2337/db12-0975 · Cited by 455
Takikawa, M., Inoue, S., Horio, F., & Tsuda, T. (2010) · Journal of Nutrition · doi:10.3945/jn.109.118216 · Cited by 448
Intake of Fruit, Vegetables, and Fruit Juices and Risk of Diabetes in Women
Bazzano, L. A., Li, T. Y., Joshipura, K. J., & Hu, F. B. (2008) · Diabetes Care · doi:10.2337/dc08-0080 · Cited by 437
Self-citationUSDA Database for the Flavonoid Content of Selected Foods Release 3.1
Bhagwat, S. A., Haytowitz, D. B., & Holden, J. M. (2015) · Cited by 407
Nakatani, N., Kayano, S.-I., Kikuzaki, H., Sumino, K., Katagiri, K., & Mitani, T. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf000422s · Cited by 399
Yoshino, J., Conte, C., Fontana, L., Mittendorfer, B., Imai, S., Schechtman, K. B., Gu, C. C., Kunz, I., Fanelli, F. R., Patterson, B. W., et al. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.09.015 · Cited by 389
Song, Y., Manson, J. E., Buring, J. E., Sesso, H. D., & Liu, S. (2005) · Journal of the American College of Nutrition · doi:10.1080/07315724.2005.10719488 · Cited by 389
Self-citationDipeptidyl Peptidase-4 Inhibition and the Treatment of Type 2 Diabetes
Drucker, D. J. (2007) · Diabetes Care · doi:10.2337/dc07-0228 · Cited by 367
Dietary fiber, glycemic load, and risk of non-insulin-dependent diabetes mellitus in women
Salmerón, J. (1997) · JAMA · doi:10.1001/jama.277.6.472 · Cited by 346
Dragović‐Uzelac, V., Levaj, B., Mrkić, V., Kovačević, D. B., & Boras, M. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2006.04.001 · Cited by 313
Fruit and vegetable intake and type 2 diabetes: EPIC-InterAct prospective study and meta-analysis
Cooper, A., Forouhi, N. G., Ye, Z., Buijsse, B., Arriola, L., Balkau, B., Barricarte, A., Beulens, J. W. J., Boeing, H., Büchner, F. L., et al. (2012) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2012.85 · Cited by 282
Ong, K. W., Hsu, A., & Tan, B. K. H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032718 · Cited by 270
Cooper, A., Sharp, S. J., Lentjes, M. A. H., Luben, R., Khaw, K., Wareham, N. J., & Forouhi, N. G. (2012) · Diabetes Care · doi:10.2337/dc11-2388 · Cited by 255
The role of dietary fiber in satiety, glucose, and insulin: studies with fruit and fruit juice
Bolton, R. P., Heaton, K. W., & Burroughs, L. F. (1981) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/34.2.211 · Cited by 247
Food consumption and the incidence of type II diabetes mellitus
Montonen, J., Järvinen, R., Heliövaara, M., Reunanen, A., Aromaa, A., & Knekt, P. (2005) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602094 · Cited by 237
USDA Database for the Flavonoid Content of Selected Foods Release 3.2
Haytowitz, D. B. (2015) · Cited by 233
Lotito, S. B., & Frei, B. B. (2003) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2003.10.005 · Cited by 228
Livesey, G., Taylor, R., Livesey, H. F., & Liu, S. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.041467 · Cited by 213
Processed meat intake and incidence of Type 2 diabetes in younger and middle-aged women
Schulze, M. B., Manson, J. E., Willett, W. C., & Hu, F. B. (2003) · Diabetologia · doi:10.1007/s00125-003-1220-7 · Cited by 210
Self-citationA Prospective Study of Fruit and Vegetable Intake and the Risk of Type 2 Diabetes in Women
Liu, S., Serdula, M. K., Janket, S., Cook, N. R., Sesso, H. D., Willett, W. C., Manson, J. E., & Buring, J. E. (2004) · Diabetes Care · doi:10.2337/diacare.27.12.2993 · Cited by 208
Self-citationVegetable but Not Fruit Consumption Reduces the Risk of Type 2 Diabetes in Chinese Women
Villegas, R., Shu, X. O., Gao, Y., Yang, G., Elasy, T. A., Li, H., & Zheng, W. (2008) · Journal of Nutrition · doi:10.1093/jn/138.3.574 · Cited by 189
Jenkins, D. J. A., Srichaikul, K., Kendall, C. W. C., Sievenpiper, J. L., Abdulnour, S., Mirrahimi, A., Meneses, C., Nishi, S., He, X., Lee, S., et al. (2011) · Diabetologia · doi:10.1007/s00125-010-1927-1 · Cited by 130
Dong, J.-Y., Zhang, L., Zhang, Y.-H., & Qin, L.-Q. (2011) · British Journal Of Nutrition · doi:10.1017/s000711451100540x · Cited by 124
DPP-IV inhibitory potential of naringin: An in silico, in vitro and in vivo study
Parmar, H. S., Jain, P., Chauhan, D. S., Bhinchar, M. K., Munjal, V., Yusuf, M., Choube, K., Tawani, A., Tiwari, V., Manivannan, E., et al. (2012) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2012.02.011 · Cited by 99
Nettleton, J. A., Harnack, L., Scrafford, C., Mink, P. J., Barraj, L. M., & Jacobs, D. R. (2006) · Journal of Nutrition · doi:10.1093/jn/136.12.3039 · Cited by 99
Tunnicliffe, J. M., Eller, L. K., Reimer, R. A., Hittel, D. S., & Shearer, J. (2011) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h11-072 · Cited by 64
Kurotani, K., Nanri, A., Goto, A., Mizoue, T., Noda, M., Kato, M., Inoue, M., & Tsugane, S. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512001705 · Cited by 58
Antioxidant Potential of Peels and Fleshes of Peaches from Different Cultivars
Rossato, S. B., Haas, C. B., Raseira, M. D. C. B., Moreira, J. C. F., & Zuanazzi, J. Â. S. (2009) · Journal of Medicinal Food · doi:10.1089/jmf.2008.0267 · Cited by 47
DIETARY LIPIDS AND SERUM CHOLESTEROL LEVEL
Shekelle, R. B., Stamler, J., Paul, O., Shryock, A. M., Liu, S., & Lepper, M. M. (1982) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113332 · Cited by 43
Willis, H. J., Thomas, W. T. B., Willis, D. J., & Slavin, J. L. (2011) · Appetite · doi:10.1016/j.appet.2011.03.006 · Cited by 34
Dietary flavonoid intakes and risk of type 2 diabetes in US men and women
Wedick, N. M., Pan, A., Cassidy, A., Rimm, E. B., Sampson, L., ROSNER, B. A., Willett, W. C., Willett, W. C., Hu, F. B., Sun, Q., et al. (2012) · SciVee · doi:10.4016/39918.01 · Cited by 30
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Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems
Willett, W., Rockström, J., Loken, B., Springmann, M., Lang, T., Vermeulen, S., Garnett, T., Tilman, D., DeClerck, F., Wood, A., et al. (2019) · The Lancet · doi:10.1016/s0140-6736(18)31788-4 · Cited by 10,880
Self-citationPrevention and management of type 2 diabetes: dietary components and nutritional strategies
Ley, S. H., Hamdy, O., Mohan, V., & Hu, F. B. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60613-9 · Cited by 1,301
Self-citationSatija, A., Bhupathiraju, S. N., Rimm, E. B., Spiegelman, D., Chiuve, S. E., Borgi, L., Willett, W. C., Manson, J. E., Sun, Q., & Hu, F. B. (2016) · PLOS Medicine · doi:10.1371/journal.pmed.1002039 · Cited by 1,069
Self-citationImamura, F., O’Connor, L., Ye, Z., Mursu, J., Hayashino, Y., Bhupathiraju, S. N., & Forouhi, N. G. (2015) · BMJ · doi:10.1136/bmj.h3576 · Cited by 977
Self-citationImamura, F., O’Connor, L., Ye, Z., Mursu, J., Hayashino, Y., Bhupathiraju, S. N., & Forouhi, N. G. (2016) · British Journal of Sports Medicine · doi:10.1136/bjsports-2016-h3576rep · Cited by 968
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Metadata
- Authors
- Muraki, I., Imamura, F., Manson, J. E., Hu, F. B., Willett, W. C., van Dam, R. M., & Sun, Q.
- Affiliations
- Harvard University (US)
- University of Cambridge (GB)
- Brigham and Women's Hospital (US)
- Corresponding author
- Sun, Q.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2013-08-28
- Volume
- 347
- Issue
- aug28 1
- Pages
- f5001-f5001
- ISSN
- 1756-1833 (ISSN-L)
- PMC
- PMC3978819
- OpenAlex
- W2010234625
- Cited by
- 544
- References
- 60
- Citations by year
- 2026: 20 · 2025: 33 · 2024: 40 · 2023: 32 · 2022: 54 · 2021: 50 · 2020: 57 · 2019: 40 · 2018: 37 · 2017: 35 · 2016: 51 · 2015: 46 · 2014: 42 · 2013: 7
- FWCI
- 6.94
- Type
- journal article
- Language
- en
- Update notices
- correction (2013-12-04)
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- BMJ (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
- National University of Singapore (submittedVersion)
- Funders
- Medical Research Council (MC_UU_12015/5)
- National Heart, Lung, and Blood Institute (R00HL098459)
- National Cancer Institute (CA-167552, CA-87969, CA-55075, P01CA087969, CA50385, UM1CA176726, CA176726, P01CA055075, R01CA050385, UM1CA167552)
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK058845, DK-082486, R01DK082486, DK58845, T32DK007703)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Keywords
- type 2 diabetes, fruit consumption, whole fruit, fruit juice, blueberry, prunes, banana, grapefruit, strawberry, cantaloupe, dietary risk factors, Nurses' Health Study, Health Professionals Follow-up Study, prospective cohort, pooled hazard ratio, diabetes prevention
- MeSH terms
- Beverages, Diabetes Mellitus, Type 2, Diet, Epidemiologic Methods, Female, Fruit, Humans, Male, Middle Aged, Prospective Studies, Risk Factors, Body Mass Index
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