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Cited by 166Gut microbiota and healthInfant Nutrition and HealthProbiotics and Fermented Foods

The human intestinal microbiome at extreme ages of life. Dietary intervention as a way to counteract alterations

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Salazar, Nuria, Arboleya, Silvia, Valdés, Lorena, Stanton, Catherine, Ross, Paul, Ruiz, Lorena, Gueimonde, Miguel, de los Reyes-Gavilán, Clara G.·2014·Frontiers in Genetics
DOI 10.3389/fgene.2014.00406PMC PMC4240173
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Abstract

The intestinal microbiome is defined as the assembly of genomes from microorganisms inhabiting the gut. This microbial ecosystem regulates important functions of the host and its correct composition and functionality is essential for a "healthy status." Metagenomic studies have highlighted variations of the intestinal microbiota as a function of age and diet. Colonization of the infant gut starts at birth and is influenced by feeding habits (formula vs. breast-feeding), birth mode and antibiotic exposure. The intestinal microbiota of full-term vaginally delivered breast-fed infants is considered the gold-standard, representing the reference for studies of alterations in other pediatric populations. At 2-3 years of age, the intestinal microbiota reaches a composition similar to adults, remaining without noticeable variations until senescence, when microbial instability and changes reappear. Here we summarize the current knowledge on intestinal microbiota alterations at extreme stages of life and tools for designing differentiated nutritional strategies by the use of probiotics, prebiotics and specific nutrients in order to restore a balanced microbiota and to improve immune and nutritional status.

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  • At both extremes of life, the microbiota is characteristically different from the typical adult gut microbiota in both levels of diversity and representation of specific taxa.

    “At both extremes of life, the microbiota is characteristically different from the typical adult gut microbiota in both levels of diversity and representation of specific taxa (Claesson et al., 2012;Salazar et al., 2014;Yatsunenko et al., 2012).”

    From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Salazar et al., 2014

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Authors
Salazar, N., Arboleya, S., Valdés, L., Stanton, C., Ross, P., Ruiz, L., Gueimonde, M., & de los Reyes-Gavilán, C. G.
Affiliations
  • Consejo Superior de Investigaciones Científicas (ES)
  • Teagasc - The Irish Agriculture and Food Development Authority (IE)
ORCID
Venue
Frontiers in Genetics
Publisher
Frontiers Media SA
Published
2014-11-21
Volume
5
Pages
406-406
ISSN
1664-8021 (ISSN-L)
DOI
10.3389/fgene.2014.00406
PMC
PMC4240173
OpenAlex
W1988506400
Cited by
166
References
93
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FWCI
1.32
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Frontiers in Genetics (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DIGITAL.CSIC (Spanish National Research Council (CSIC)) (acceptedVersion)
  • DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Science Foundation Ireland
  • Ministerio de Economía y Competitividad (AGL2013, AGL2013‐43770‐R, AGL2010-16525)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Keywords
gut microbiota, infant gut colonization, breastfeeding, bottle feeding, mode of delivery, antibiotic exposure, probiotics, prebiotics, dietary intervention, immune status, nutritional status

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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