Gut Microbiota Modification: Another Piece in the Puzzle of the Benefits of Physical Exercise in Health?
Open accessAbstract
Regular physical exercise provides many health benefits, protecting against the development of chronic diseases, and improving quality of life. Some of the mechanisms by which exercise provides these effects are the promotion of an anti-inflammatory state, reinforcement of the neuromuscular function, and activation of the hypothalamic-pituitary-adrenal (HPA) axis. Recently, it has been proposed that physical exercise is able to modify gut microbiota, and thus this could be another factor by which exercise promotes well-being, since gut microbiota appears to be closely related to health and disease. The purpose of this paper is to review the recent findings on gut microbiota modification by exercise, proposing several mechanisms by which physical exercise might cause changes in gut microbiota.
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Exercise appears to be able to enrich microbiota diversity.
“Exercise appears to be able to enrich microbiota diversity [20–25]”
From International Society of Sports Nutrition Position Stand: Probiotics (2019) · cites this paper as [21]
The microbiota has an indirect influence on various indices of exercise performance, recovery, and patterns of illness, such as signaling through myokines and other cytokines, modulating activation of the hypothalamic-pituitary-adrenal axis, and affecting performance-associated metabolic pathways.
“The microbiota has an indirect influence on various indices of exercise performance, recovery, and patterns of illness, such as signaling through myokines and other cytokines, modulating activation of the hypothalamic–pituitary–adrenal axis, and affecting performance-associated metabolic pathways [13, 16–18].”
From The athletic gut microbiota (2020) · cites this paper as [17]
Exercise influences the composition of the gut microbiota community.
“These preliminary studies indicate that exercise influences the composition of the gut microbiota community.”
From The athletic gut microbiota (2020) · cites this paper as [17]
A common finding in murine studies examining the effects of exercise training on the gut microbiome is an increase in alpha diversity.
“A common finding in these murine studies examining the effects of exercise training on the gut microbiome, is an increase in alpha diversity [17].”
From The athletic gut microbiota (2020) · cites this paper as [17]
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- Authors
- Cerdá, B., Pérez, M., Pérez-Santiago, J. D., Tornero-Aguilera, J. F., González-Soltero, R., & Larrosa, M.
- Affiliations
- Universidad Europea de Madrid (ES)
- Corresponding author
- Larrosa, Mar
- Venue
- Frontiers in Physiology
- Publisher
- Frontiers Media SA
- Published
- 2016-02-18
- Volume
- 7
- Pages
- 51-51
- ISSN
- 1664-042X (ISSN-L)
- PMC
- PMC4757670
- OpenAlex
- W2262964121
- Cited by
- 247
- References
- 134
- Citations by year
- 2026: 14 · 2025: 11 · 2024: 33 · 2023: 33 · 2022: 28 · 2021: 24 · 2020: 24 · 2019: 37 · 2018: 18 · 2017: 17 · 2016: 7
- FWCI
- 2.38
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Physiology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- ABACUS. Repositorio de Producción Científica (Universidad Europea) (submittedVersion, cc-by)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Ramón y Cajal fellowship
- Ministerio de Economía y Competitividad
- Universidad Europea de Madrid (2015UEM24, 2015UEM46)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Keywords
- gut microbiota, physical activity, anti-inflammatory activity, hypothalamic-pituitary-adrenal axis, neuromuscular function, chronic disease prevention
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