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The Pathophysiology Of Tumor Necrosis Factors
Abstract
Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More
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“…Marino et al., 1997; Novosad and Winthrop, 2014; Pfeffer et al., 1993; Vassalli, 1992), overproduction of TNF is a typical feature of autoimmune and other chronic inflammatory diseases, leading to tissue destruction in mice and humans (Atreya et al., 2014; Riminton et al., 1998; Vassalli, 1992).”
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“TNF-a is produced by macrophages and circulating monocytes and plays an important role in a wide range of immune reactions, including autoimmune conditions (Vassalli 1992).”
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Metadata
- Authors
- VASSALLI, P.
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 1992-01-01
- Volume
- 10
- Issue
- 1
- Pages
- 411-452
- ISSN
- 0732-0582 (ISSN-L)
- OpenAlex
- W2176899369
- Cited by
- 1,920
- References
- 0
- FWCI
- 29.74
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
