THE SYNAPTIC VESICLE CYCLE

Short-Term Synaptic Plasticity

Zucker, R. S., & Regehr, W. G. (2002) · Annual Review of Physiology · doi:10.1146/annurev.physiol.64.092501.114547 · Cited by 5,068

SNAP receptors implicated in vesicle targeting and fusion

Söllner, T. H., Whiteheart, S. W., Brunner, M., Erdjument‐Bromage, H., Geromanos, S. J., Tempst, P., & Rothman, J. E. (1993) · Nature · doi:10.1038/362318a0 · Cited by 3,239

EVIDENCE FOR RECYCLING OF SYNAPTIC VESICLE MEMBRANE DURING TRANSMITTER RELEASE AT THE FROG NEUROMUSCULAR JUNCTION

Heuser, J. E., & Reese, T. S. (1973) · The Journal of Cell Biology · doi:10.1083/jcb.57.2.315 · Cited by 2,147

The synaptic vesicle cycle: a cascade of protein–protein interactions

Südhof, T. C. (1995) · Nature · doi:10.1038/375645a0 · Cited by 1,991

Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse

Geppert, M., Goda, Y., Hammer, R. E., Li, C., Rosahl, T. W., Stevens, C. F., & Südhof, T. C. (1994) · Cell · doi:10.1016/0092-8674(94)90556-8 · Cited by 1,483

Synaptic assembly of the brain in the absence of neurotransmitter secretion.

Verhage, M., Maia, A., Plomp, J., Brussaard, A., Heeroma, J., Vermeer, H., Toonen, R., Hammer, R., van den Berg, T. K., Missler, M., et al. (2000) · Science · doi:10.1126/science.287.5454.864 · Cited by 1,387

Membrane Fusion

Jahn, R., Lang, T., & Südhof, T. C. (2003) · Cell · doi:10.1016/s0092-8674(03)00112-0 · Cited by 1,364

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

Bennett, M. K., Calakos, N., & Scheller, R. H. (1992) · Science · doi:10.1126/science.1321498 · Cited by 1,263

SNARE-mediated membrane fusion

Chen, Y. A., & Scheller, R. H. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35052017 · Cited by 1,133

Definition of the readily releasable pool of vesicles at hippocampal synapses.

Rosenmund, C., & Stevens, C. (1996) · Neuron · doi:10.1016/s0896-6273(00)80146-4 · Cited by 1,084

Vitamin D and Its Potential Interplay With Pain Signaling Pathways

Habib, A. M., Nagi, K., Thillaiappan, N. B., Sukumaran, V., & Akhtar, S. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00820 · Cited by 127

Classification of four distinct osteoarthritis subtypes with a knee joint tissue transcriptome atlas

Yuan, C., Pan, Z., Zhao, K., Li, J., Sheng, Z., Yao, X., Liu, H., Zhang, X., Yang, Y., Yu, D., et al. (2020) · Bone Research · doi:10.1038/s41413-020-00109-x · Cited by 127

Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses

Johnson, S. L., Franz, C., Kuhn, S. A. C., Furness, D. N., Rüttiger, L., Münkner, S., Rivolta, M. N., Seward, E. P., Herschman, H. R., Engel, J., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2456 · Cited by 127

Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load

Milnerwood, A. J., & Raymond, L. A. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.142448 · Cited by 126

Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE–Sec1/Munc18 membrane fusion complex

Rathore, S. S., Bend, E. G., Yu, H., Hammarlund, M., Jørgensen, E. M., & Shen, J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1012997108 · Cited by 126

Limited Intermixing of Synaptic Vesicle Components upon Vesicle Recycling

Opazo, F., Punge, A., Bückers, J., Hoopmann, P., Kastrup, L., Hell, S. W., & Rizzoli, S. O. (2010) · Traffic · doi:10.1111/j.1600-0854.2010.01058.x · Cited by 125

The architecture of an excitatory synapse

Chua, J. J. E., Kindler, S., Boyken, J., & Jahn, R. (2010) · Journal of Cell Science · doi:10.1242/jcs.052696 · Cited by 125

Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice

Kim, S., Zhang, Z., Sarkar, C., Tsai, P., Lee, Y., Dye, L., & Mukherjee, A. B. (2008) · Journal of Clinical Investigation · doi:10.1172/jci33482 · Cited by 125

Global and local missions of cAMP signaling in neural plasticity, learning, and memory

Lee, D. (2015) · Frontiers in Pharmacology · doi:10.3389/fphar.2015.00161 · Cited by 124

The Transgenic Overexpression of α-Synuclein and Not Its Related Pathology Associates with Complex I Inhibition

Loeb, V., Yakunin, E., Saada, A., & Sharon, R. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.061051 · Cited by 124

Dynamic Ca 2+ -Dependent Stimulation of Vesicle Fusion by Membrane-Anchored Synaptotagmin 1

Lee, H.-K., Yang, Y., Su, Z., Hyeon, C., Lee, T.-S., Lee, H.-W., Kweon, D.-H., Shin, Y.-K., & Yoon, T.-Y. (2010) · Science · doi:10.1126/science.1187722 · Cited by 123

Beyond BOTOX: advantages and limitations of individual botulinum neurotoxins

Davletov, B. A., Bajohrs, M., & Binz, T. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.06.001 · Cited by 123

Studying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system

Kyoung, M., Zhang, Y., Diao, J., Chu, S., & Brünger, A. T. (2012) · Nature Protocols · doi:10.1038/nprot.2012.134 · Cited by 123

Optical quantal analysis of synaptic transmission in wild-type and rab3-mutant Drosophila motor axons

Peled, E. S., & Isacoff, E. Y. (2011) · Nature Neuroscience · doi:10.1038/nn.2767 · Cited by 123

Streamlined Synaptic Vesicle Cycle in Cone Photoreceptor Terminals

Rea, R., Li, J., Dharia, A., Levitan, E. S., Sterling, P., & Krämer, R. (2004) · Neuron · doi:10.1016/s0896-6273(04)00088-1 · Cited by 123

Different Effects on Fast Exocytosis Induced by Synaptotagmin 1 and 2 Isoforms and Abundance But Not by Phosphorylation

Nagy, G., Kim, J. H., Pang, Z. P., Matti, U., Rettig, J., Südhof, T. C., & Sørensen, J. B. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2589-05.2006 · Cited by 122

A dominant mutation in Snap25 causes impaired vesicle trafficking, sensorimotor gating, and ataxia in the blind-drunk mouse

Jeans, A. F., Oliver, P. L., Johnson, R., Capogna, M., Vikman, J., Molnár, Z., Babbs, A., Partridge, C. J., Salehi, A. A., Bengtsson, M., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610222104 · Cited by 122

Ca2+ microdomains and the control of insulin secretion

Rutter, G. A., Tsuboi, T., & Ravier, M. A. (2006) · Cell Calcium · doi:10.1016/j.ceca.2006.08.015 · Cited by 121

Synaptophysin Is Required for Synaptobrevin Retrieval during Synaptic Vesicle Endocytosis

Gordon, S. L., Leube, R. E., & Cousin, M. A. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.3162-11.2011 · Cited by 121

Zebrafish survival motor neuron mutants exhibit presynaptic neuromuscular junction defects

Boon, K.-L., Xiao, S., McWhorter, M. L., Donn, T. M., Wolf-Saxon, E. R., Bohnsack, M. T., Moens, C. B., & Beattie, C. E. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp310 · Cited by 120

Dysfunction of spatacsin leads to axonal pathology in SPG11-linked hereditary spastic paraplegia

Pérez‐Brangulí, F., Mishra, H. K., Prots, I., Havlicek, S., Kohl, Z., Saul, D., Rummel, C., Dorca‐Arévalo, J., Regensburger, M., Graef, D., et al. (2014) · Human Molecular Genetics · doi:10.1093/hmg/ddu200 · Cited by 120

The Presynaptic Dense Projection of theCaenorhabiditis elegansCholinergic Neuromuscular Junction Localizes Synaptic Vesicles at the Active Zone through SYD-2/Liprin and UNC-10/RIM-Dependent Interactions

Stigloher, C., Zhan, H., Zhen, M., Richmond, J. E., & Bessereau, J. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6164-10.2011 · Cited by 119

Novel Cellular Functions of Very Long Chain-Fatty Acids: Insight From ELOVL4 Mutations

Deák, F., Anderson, R. E., Fessler, J. L., & Sherry, D. M. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00428 · Cited by 119

Synaptotagmin-1 Utilizes Membrane Bending and SNARE Binding to Drive Fusion Pore Expansion

Lynch, K. L., Gerona, R. R. L., Kielar, D. M., Martens, S., McMahon, H. T., & Martin, T. F. J. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-03-0235 · Cited by 119

A Voltage-Gated Calcium Channel Regulates Lysosomal Fusion with Endosomes and Autophagosomes and Is Required for Neuronal Homeostasis

Tian, X., Gala, U., Zhang, Y., Shang, W., Nagarkar-Jaiswal, S., di Ronza, A., Jaiswal, M., Yamamoto, S., Sandoval, H., Duraine, L., et al. (2015) · PLoS Biology · doi:10.1371/journal.pbio.1002103 · Cited by 118

N-Cadherin Transsynaptically Regulates Short-Term Plasticity at Glutamatergic Synapses in Embryonic Stem Cell-Derived Neurons

Jüngling, K., Eulenburg, V., Moore, R. H., Kemler, R., Leßmann, V., & Gottmann, K. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1013-06.2006 · Cited by 118

Expression and Function of SNAP-25 as a Universal SNARE Component in GABAergic Neurons

Tafoya, L. C. R., Mameli, M., Miyashita, T., Guzowski, J. F., Valenzuela, C. F., & Wilson, M. C. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1866-06.2006 · Cited by 118

Proepileptic phenotype of SV2A‐deficient mice is associated with reduced anticonvulsant efficacy of levetiracetam

Kaminski, R. M., Gillard, M. R., Leclercq, K., Hanon, É., Lorent, G., Dassesse, D., Matagne, A., & Klitgaard, H. (2009) · Epilepsia · doi:10.1111/j.1528-1167.2009.02089.x · Cited by 118

Studying vesicle cycling in presynaptic terminals using the genetically encoded probe synaptopHluorin

Burrone, J., Li, Z., & Murthy, V. N. (2006) · Nature Protocols · doi:10.1038/nprot.2006.449 · Cited by 118

Synaptic Vesicle Endocytosis at a CNS Nerve Terminal: Faster Kinetics at Physiological Temperatures and Increased Endocytotic Capacity During Maturation

Renden, R., & von Gersdorff, H. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00898.2007 · Cited by 118

Munc13‐2 −/− baseline secretion defect reveals source of oligomeric mucins in mouse airways

Zhu, Y., Ehré, C., Abdullah, L. H., Sheehan, J. K., Roy, M. G., Evans, C. M., Dickey, B. F., & Davis, C. W. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2007.149310 · Cited by 117

Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons

Dong, M., Tepp, W. H., Liu, H., Johnson, E. A., & Chapman, E. R. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200707184 · Cited by 117

The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM

Yap, C. C., Wisco, D. R., Kujala, P., Lasiecka, Z. M., Cannon, J. T., Chang, M. C. S., Hirling, H., Klumperman, J., & Winckler, B. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200707143 · Cited by 117

Role for the actomyosin complex in regulated exocytosis revealed by intravital microscopy

Masedunskas, A., Šrámková, M., Parente, L., Sales, K. U., Amornphimoltham, P., Bugge, T. H., & Weigert, R. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016778108 · Cited by 116

Retrograde GABA Signaling Adjusts Sound Localization by Balancing Excitation and Inhibition in the Brainstem

Magnusson, A. K., Park, T. J., Pecka, M., Grothe, B., & Koch, U. (2008) · Neuron · doi:10.1016/j.neuron.2008.05.011 · Cited by 116

Rab27b Regulates Mast Cell Granule Dynamics and Secretion

Mizuno, K., Tolmachova, T., Ushakov, D. S., Romao, M., Åbrink, M., Ferenczi, M. A., Raposo, G., & Seabra, M. C. (2007) · Traffic · doi:10.1111/j.1600-0854.2007.00571.x · Cited by 116

Synaptotagmins bind calcium to release insulin

Gauthier, B. R., & Wollheim, C. B. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90568.2008 · Cited by 115

Mutation in Rab3 GTPase-Activating Protein (RAB3GAP) Noncatalytic Subunit in a Kindred with Martsolf Syndrome

Aligianis, I. A., Morgan, N. V., Mione, M., Johnson, C. A., Rosser, E. M., Hennekam, R. C. M., Adams, G., Trembath, R. C., Pilz, D. T., Stoodley, N., et al. (2006) · The American Journal of Human Genetics · doi:10.1086/502681 · Cited by 115

Macromolecular connections of active zone material to docked synaptic vesicles and presynaptic membrane at neuromuscular junctions of mouse

Nagwaney, S., Harlow, M. L., Jung, J. H., Szule, J. A., Ress, D. B., Xu, J., Marshall, R. M., & McMahan, U. J. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.21975 · Cited by 115

SAD: A Presynaptic Kinase Associated with Synaptic Vesicles and the Active Zone Cytomatrix that Regulates Neurotransmitter Release

Inoue, E., Mochida, S., Takagi, H., Higa, S., Deguchi‐Tawarada, M., Takao‐Rikitsu, E., Inoue, M., Yao, I., Takeuchi, K., Kitajima, I., et al. (2006) · Neuron · doi:10.1016/j.neuron.2006.03.018 · Cited by 115

Mechanical unzipping and rezipping of a single SNARE complex reveals hysteresis as a force-generating mechanism

Min, D., Kim, K., Hyeon, C., Cho, Y. H., Shin, Y., & Yoon, T. (2013) · Nature Communications · doi:10.1038/ncomms2692 · Cited by 114

Blocking Endocytosis Enhances Short-Term Synaptic Depression under Conditions of Normal Availability of Vesicles

Hua, Y., Woehler, A., Kahms, M., Haucke, V., Neher, E., & Klingauf, J. (2013) · Neuron · doi:10.1016/j.neuron.2013.08.010 · Cited by 114

Presynaptic enzymatic neurotoxins

Rossetto, O., Morbiato, L., Caccin, P., Rigoni, M., & Montecucco, C. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03965.x · Cited by 114

Rab3 GTPase-activating protein regulates synaptic transmission and plasticity through the inactivation of Rab3

Sakane, A., Manabe, S., Ishizaki, H., Tanaka, M., Kiyokage, E., Toida, K., Yoshida, T., Miyoshi, J., Kamiya, H., Takai, Y., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600304103 · Cited by 114

Activity-dependent phosphorylation of Ser187 is required for SNAP-25-negative modulation of neuronal voltage-gated calcium channels

Pozzi, D., Condliffe, S. B., Bozzi, Y., Chikhladze, M., Grumelli, C., Proux‐Gillardeaux, V., Takahashi, M., Franceschetti, S., Verderio, C., & Matteoli, M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706211105 · Cited by 114

Prolonged Exposure to Levetiracetam Reveals a Presynaptic Effect on Neurotransmission

Yang, X., Weisenfeld, A., & Rothman, S. M. (2007) · Epilepsia · doi:10.1111/j.1528-1167.2006.01132.x · Cited by 114

A Gain-of-Function Mutation in Synaptotagmin-1 Reveals a Critical Role of Ca 2+ -Dependent Soluble N -Ethylmaleimide-Sensitive Factor Attachment Protein Receptor Complex Binding in Synaptic Exocytosis

Pang, Z. P., Shin, O.-H., Meyer, A. C., Rosenmund, C., & Südhof, T. C. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.3804-06.2006 · Cited by 113

The Synaptic Vesicle Glycoprotein 2: Structure, Function, and Disease Relevance

Stout, K. A., Dunn, A. R., Hoffman, C., & Miller, G. W. (2019) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.9b00351 · Cited by 112

How do the Botulinum Neurotoxins block neurotransmitter release: from botulism to the molecular mechanism of action

Poulain, B., Popoff, M. R., & Molgó, J. (2008) · The Botulinum J · doi:10.1504/tbj.2008.018951 · Cited by 112

The NGL family of leucine-rich repeat-containing synaptic adhesion molecules

Woo, J., Kwon, S., & Kim, E. (2009) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2009.05.008 · Cited by 112

Calcium homeostasis in aging neurons

Nikoletopoulou, V., & Tavernarakis, N. (2012) · Frontiers in Genetics · doi:10.3389/fgene.2012.00200 · Cited by 112

The SNARE Machinery in Mast Cell Secretion

Lorentz, A., Baumann, A., Vitte, J., & Blank, U. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00143 · Cited by 112

Neurons derived from different brain regions are inherently different in vitro: a novel multiregional brain-on-a-chip

Dauth, S., Maoz, B. M., Sheehy, S. P., Hemphill, M. A., Murty, T., Macedonia, M. K., Greer, A. M., Budnik, B., & Parker, K. K. (2016) · Journal of Neurophysiology · doi:10.1152/jn.00575.2016 · Cited by 112

Mobility of Synaptic Vesicles in Different Pools in Resting and Stimulated Frog Motor Nerve Terminals

Gaffield, M. A., Rizzoli, S. O., & Betz, W. J. (2006) · Neuron · doi:10.1016/j.neuron.2006.06.031 · Cited by 111

Mechanical Properties of Respiratory Muscles

Sieck, G. C., Ferreira, L. F., Reid, M. B., & Mantilla, C. B. (2013) · Comprehensive physiology · doi:10.1002/cphy.c130003 · Cited by 111

Amyloid Precursor Protein Is Trafficked and Secreted via Synaptic Vesicles

Groemer, T. W., Thiel, C. S., Holt, M. G., Riedel, D., Hua, Y., Hüve, J., Wilhelm, B. G., & Klingauf, J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018754 · Cited by 111

Quantitative Analysis of Synaptic Vesicle Rabs Uncovers Distinct Yet Overlapping Roles for Rab3a and Rab27b in Ca 2+ -Triggered Exocytosis

Pavlos, N. J., Grønborg, M., Riedel, D., Chua, J. J. E., Boyken, J., Kloepper, T. H., Urlaub, H., Rizzoli, S. O., & Jahn, R. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0907-10.2010 · Cited by 110

Rim2α Determines Docking and Priming States in Insulin Granule Exocytosis

Yasuda, T., Shibasaki, T., Minami, K., Takahashi, H., Mizoguchi, A., Uriu, Y., Numata, T., Mori, Y., Miyazaki, J.-I., Miki, T., et al. (2010) · Cell Metabolism · doi:10.1016/j.cmet.2010.05.017 · Cited by 110

Rab3-GAP Controls the Progression of Synaptic Homeostasis at a Late Stage of Vesicle Release

Müller, M., Pym, E. C. G., Tong, A., & Davis, G. W. (2011) · Neuron · doi:10.1016/j.neuron.2011.01.025 · Cited by 109

Oligomeric α-Syn and SNARE complex proteins in peripheral extracellular vesicles of neural origin are biomarkers for Parkinson's disease

Agliardi, C., Meloni, M., Guerini, F. R., Zanzottera, M., Bolognesi, E., Baglio, F., & Clerici, M. (2020) · Neurobiology of Disease · doi:10.1016/j.nbd.2020.105185 · Cited by 109

Enlargeosome Traffic: Exocytosis Triggered by Various Signals Is Followed by Endocytosis, Membrane Shedding or Both

Cocucci, E., Racchetti, G., Podini, P., & Meldolesi, J. (2007) · Traffic · doi:10.1111/j.1600-0854.2007.00566.x · Cited by 108

Digital in vivo 3D atlas of the antennal lobe of Drosophila melanogaster

Grabe, V., Strutz, A., Baschwitz, A., Hansson, B. S., & Sachse, S. (2014) · The Journal of Comparative Neurology · doi:10.1002/cne.23697 · Cited by 108

Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses

Scheuber, A., Rudge, R., Danglot, L., Raposo, G., Binz, T., Poncer, J. C., & Galli, T. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603511103 · Cited by 108

Dysregulation of BDNF-TrkB Signaling in Developing Hippocampal Neurons by Pb2+: Implications for an Environmental Basis of Neurodevelopmental Disorders

Stansfield, K. H., Pilsner, J. R., Lu, Q., Wright, R. O., & Guilarte, T. R. (2012) · Toxicological Sciences · doi:10.1093/toxsci/kfs090 · Cited by 108

Perineuronal Nets and Their Role in Synaptic Homeostasis

Bosiacki, M., Gąssowska-Dobrowolska, M., Kojder, K., Fabiańska, M., Jeżewski, D., Gutowska, I., & Lubkowska, A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20174108 · Cited by 107

Single-Molecule Studies of the Neuronal SNARE Fusion Machinery

Brunger, A. T., Weninger, K., Bowen, M., & Chu, S. (2009) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.77.070306.103621 · Cited by 107

Exosome: A novel neurotransmission modulator or non-canonical neurotransmitter?

Xia, X., Wang, Y., Qin, Y., Zhao, S., & Zheng, J. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101558 · Cited by 107

α-Synuclein: A Multifunctional Player in Exocytosis, Endocytosis, and Vesicle Recycling

Huang, M., Wang, B., Li, X., Fu, C., Wang, C., & Kang, X. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00028 · Cited by 106

Binding of the Munc13-1 MUN Domain to Membrane-Anchored SNARE Complexes

Guan, R. J., Dai, H., & Rizo, J. (2008) · Biochemistry · doi:10.1021/bi702345m · Cited by 106

Liprin-α proteins: scaffold molecules for synapse maturation

Spangler, S. A., & Hoogenraad, C. C. (2007) · Biochemical Society Transactions · doi:10.1042/bst0351278 · Cited by 106

Analysis of the synaptic vesicle proteome using three gel‐based protein separation techniques

Burré, J., Beckhaus, T., Schägger, H., Corvey, C., Hofmann, S., Karas, M., Zimmermann, H., & Volknandt, W. (2006) · PROTEOMICS · doi:10.1002/pmic.200600357 · Cited by 106

Molecular mechanism of the synaptotagmin–SNARE interaction in Ca2+-triggered vesicle fusion

Vrljic, M., Strop, P., Ernst, J. A., Sutton, R. B., Chu, S., & Brünger, A. T. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1764 · Cited by 105

Binding to Rab3A-interacting Molecule RIM Regulates the Presynaptic Recruitment of Munc13-1 and ubMunc13-2

Andrews-Zwilling, Y. S., Kawabe, H., Reim, K., Varoqueaux, F., & Brose, N. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601421200 · Cited by 105

Activity-related redistribution of presynaptic proteins at the active zone

Tao-Cheng, J.-H. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.04.061 · Cited by 105

Fertilization in Mammals

Florman, H. M., & Ducibella, T. (2006) · Elsevier eBooks · doi:10.1016/b978-012515400-0/50007-5 · Cited by 105

cAMP/PKA signaling and RIM1α mediate presynaptic LTP in the lateral amygdala

Fourcaudot, E., Gambino, F., Humeau, Y., Casassus, G., Shaban, H., Poulain, B., & Lüthi, A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806938105 · Cited by 105

SNARE Complex Regulation by Phosphorylation

Snyder, D. A., Kelly, M. L., & Woodbury, D. J. (2006) · Cell Biochemistry and Biophysics · doi:10.1385/cbb:45:1:111 · Cited by 105

Competition between Bending and Internal Pressure Governs the Mechanics of Fluid Nanovesicles

Vorselen, D., MacKintosh, F. C., Roos, W. H., & Wuite, G. J. L. (2017) · ACS Nano · doi:10.1021/acsnano.6b07302 · Cited by 104

Functional and Pathological Effects of α-Synuclein on Synaptic SNARE Complexes

Gao, V., Briano, J. A., Komer, L. E., & Burré, J. (2022) · Journal of Molecular Biology · doi:10.1016/j.jmb.2022.167714 · Cited by 104

Quantification of the Brain Proteome in Alzheimer’s Disease Using Multiplexed Mass Spectrometry

Musunuri, S., Wetterhall, M., Ingelsson, M., Lannfelt, L., Artemenko, K. A., Bergquist, J., Kultima, K., & Shevchenko, G. (2014) · Journal of Proteome Research · doi:10.1021/pr401202d · Cited by 103

Formation of Golgi-Derived Active Zone Precursor Vesicles

Maas, C., Torres, V. I., Altrock, W. D., Leal‐Ortiz, S., Wagh, D. A., Terry-Lorenzo, R. T., Fejtová, A., Gundelfinger, E. D., Ziv, N. E., & Garner, C. C. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0195-12.2012 · Cited by 103

DOC2A and DOC2B are sensors for neuronal activity with unique calcium‐dependent and kinetic properties

Groffen, A. J. A., Friedrich, R., Brian, E. C., Ashery, U., & Verhage, M. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03755.x · Cited by 102

Calcium Triggers Exocytosis from Two Types of Organelles in a Single Astrocyte

Liu, T., Sun, L., Xiong, Y., Shang, S., Guo, N., Teng, S., Wang, Y., Liu, B., Wang, C., Wang, L., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6401-10.2011 · Cited by 102

GSK-3β Inhibits Presynaptic Vesicle Exocytosis by Phosphorylating P/Q-Type Calcium Channel and Interrupting SNARE Complex Formation

Zhu, L., Liu, D., Hu, J., Cheng, J. Q., Wang, S., Wang, Q., Wang, F., Chen, J., & Wang, J. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.5223-09.2010 · Cited by 102

ELKS2α/CAST deletion selectively increases neurotransmitter release at inhibitory synapses

Kaeser, P. S., Deng, L., Chávez, A. E., Liu, X., Castillo, P. E., & Südhof, T. C. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.019 · Cited by 102

V-ATPase Membrane Sector Associates with Synaptobrevin to Modulate Neurotransmitter Release

Giovanni, J. D., Boudkkazi, S., Mochida, S., Bialowas, A., Samari, N., Lévêque, C., Youssouf, F., Bréchet, A., Iborra, C., Maulet, Y., et al. (2010) · Neuron · doi:10.1016/j.neuron.2010.06.024 · Cited by 102

How synapsin I may cluster synaptic vesicles

Shupliakov, O., Haucke, V., & Pechstein, A. (2011) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2011.07.006 · Cited by 102

Munc13 controls the location and efficiency of dense-core vesicle release in neurons

van de Bospoort, R., Farina, M., Schmitz, S. K., de Jong, A. P. H., de Wit, H., Verhage, M., & Toonen, R. F. G. (2012) · The Journal of Cell Biology · doi:10.1083/jcb.201208024 · Cited by 102

Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes

Hoogenraad, C. C., Popa, I., Futai, K., Sanchez-Martinez, E., Wulf, P. S., van Vlijmen, T., Dortland, B. R., Oorschot, V., Govers, R., Monti, M., et al. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000283 · Cited by 101

Synaptic vesicle trafficking and Parkinson's disease

Esposito, G., Clara, F. A., & Verstreken, P. (2011) · Developmental Neurobiology · doi:10.1002/dneu.20916 · Cited by 101

Synaptic vesicle protein trafficking at the glutamate synapse

Santos, M., Li, H., & Voglmaier, S. M. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.03.029 · Cited by 101

Genetic Analysis of Mint/X11 Proteins: Essential Presynaptic Functions of a Neuronal Adaptor Protein Family

Ho, A., Morishita, W., Atasoy, D., Liu, X., Tabuchi, K., Hammer, R. E., Malenka, R. C., & Südhof, T. C. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2855-06.2006 · Cited by 101

Binding of Munc18-1 to Synaptobrevin and to the SNARE Four-Helix Bundle

Xu, Y., Su, L., & Rizo, J. (2010) · Biochemistry · doi:10.1021/bi9021878 · Cited by 101

RIM Promotes Calcium Channel Accumulation at Active Zones of theDrosophilaNeuromuscular Junction

Graf, E. R., Valakh, V., Wright, C. M., Wu, C., Liu, Z., Zhang, Y., & DiAntonio, A. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0965-12.2012 · Cited by 101

Synaptotagmin-1- and Synaptotagmin-7-Dependent Fusion Mechanisms Target Synaptic Vesicles to Kinetically Distinct Endocytic Pathways

Li, Y. C., Chanaday, N. L., Xu, W., & Kavalali, E. T. (2017) · Neuron · doi:10.1016/j.neuron.2016.12.010 · Cited by 101

Protein sorting in the synaptic vesicle life cycle

Bonanomi, D., Benfenati, F., & Valtorta, F. (2006) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2006.09.002 · Cited by 100

RIM1α and RIM1β Are Synthesized from Distinct Promoters of the RIM1 Gene to Mediate Differential But Overlapping Synaptic Functions

Kaeser, P. S., Kwon, H., Chiu, C. Q., Deng, L., Castillo, P. E., & Südhof, T. C. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3235-08.2008 · Cited by 100

N-Glycosylation Is Essential for Vesicular Targeting of Synaptotagmin 1

Han, W., Rhee, J., Maximov, A., Lao, Y., Mashimo, T., Rosenmund, C., & Südhof, T. C. (2004) · Neuron · doi:10.1016/s0896-6273(03)00820-1 · Cited by 100

The morphology of excitatory central synapses: from structure to function.

Rollenhagen, A., & Lübke, J. H. R. (2006) · Cell and Tissue Research · doi:10.1007/s00441-006-0288-z · Cited by 99

Correlated optical and isotopic nanoscopy

Saka, S. K., Vogts, A., Kröhnert, K., Hillion, F., Rizzoli, S. O., & Wessels, J. T. (2014) · Nature Communications · doi:10.1038/ncomms4664 · Cited by 99

Snares and Munc18 in synaptic vesicle fusion

Rizo, J., & Südhof, T. C. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn898 · Cited by 539

Molecular machines governing exocytosis of synaptic vesicles

Jahn, R., & Fasshauer, D. (2012) · Nature · doi:10.1038/nature11320 · Cited by 1,004

The molecular machinery of synaptic vesicle exocytosis

Li, L., & Chin, L. (2003) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-2240-7 · Cited by 129

Mechanism of neurotransmitter release coming into focus

Rizo, J. (2018) · Protein Science · doi:10.1002/pro.3445 · Cited by 210

3. Molecular analysis of neurotransmitter release

Schiavo, G., & Stenbeck, G. (2017) · Princeton University Press eBooks · doi:10.2307/j.ctv3hh4x0.8