Cited by 489Muscle Physiology and DisordersNutrition and Health in AgingMuscle metabolism and nutrition

The DOI matches its Crossref record; 50 of the 51 references it cites were found in a registry or an index.

Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly

Open access

Verdijk, Lex B., Koopman, René, Schaart, Gert, Meijer, Kenneth, Savelberg, Hans H. C. M., van Loon, Luc J. C.·2007·American Journal of Physiology-Endocrinology and Metabolism

DOI 10.1152/ajpendo.00278.2006

Open this paper in CoChat — free account Open PDF

Abstract

Satellite cells (SC) are essential for skeletal muscle growth and repair. Because sarcopenia is associated with type II muscle fiber atrophy, we hypothesized that SC content is specifically reduced in the type II fibers in the elderly. A total of eight elderly (E; 76 ± 1 yr) and eight young (Y; 20 ± 1 yr) healthy males were selected. Muscle biopsies were collected from the vastus lateralis in both legs. ATPase staining and a pax7-antibody were used to determine fiber type-specific SC content (i.e., pax7-positive SC) on serial muscle cross sections. In contrast to the type I fibers, the proportion and mean cross-sectional area of the type II fibers were substantially reduced in E vs. Y. The number of SC per type I fiber was similar in E and Y. However, the number of SC per type II fiber was substantially lower in E vs. Y (0.044 ± 0.003 vs. 0.080 ± 0.007; P < 0.01). In addition, in the type II fibers, the number of SC relative to the total number of nuclei and the number of SC per fiber area were also significantly lower in E. This study is the first to show type II fiber atrophy in the elderly to be associated with a fiber type-specific decline in SC content. The latter is evident when SC content is expressed per fiber or per fiber area. The decline in SC content might be an important factor in the etiology of type II muscle fiber atrophy, which accompanies the loss of skeletal muscle with aging.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1152/ajpendo.00278.2006

Cites

50 of 50 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502
SATELLITE CELL OF SKELETAL MUSCLE FIBERS
Mauro, A. (1961) · The Journal of Cell Biology · doi:10.1083/jcb.9.2.493 · Cited by 3,683
Pax7 Is Required for the Specification of Myogenic Satellite Cells
Seale, P., Sabourin, L. A., Girgis-Gabardo, A., Mansouri, A., Gruß, P., & Rudnicki, M. A. (2000) · Cell · doi:10.1016/s0092-8674(00)00066-0 · Cited by 2,345
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
Conboy, I. M., Conboy, M. J., Wagers, A. J., Girma, E. R., Weissman, I. L., & Rando, T. A. (2005) · Nature · doi:10.1038/nature03260 · Cited by 2,287
Muscle Fiber Types: How Many and What Kind?
Brooke, M. H., & Kaiser, K. K. (1970) · Archives of Neurology · doi:10.1001/archneur.1970.00480280083010 · Cited by 2,179
What is the cause of the ageing atrophy?
Lexell, J. E., Taylor, C. C., & Sjöstróm, M. (1988) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(88)90132-3 · Cited by 2,080
Myogenic satellite cells: physiology to molecular biology
Hawke, T. J., & Garry, D. J. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.91.2.534 · Cited by 1,646
High-Intensity Strength Training in Nonagenarians: Effects on Skeletal Muscle
Fiatarone, M. A. (1990) · JAMA · doi:10.1001/jama.1990.03440220053029 · Cited by 1,593
Human aging, muscle mass, and fiber type composition.
Evans, W. J., & Lexell, J. (1995) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/50a.special_issue.11 · Cited by 1,308
Percutaneous Needle Biopsy of Skeletal Muscle in Physiological and Clinical Research
Bergström, J. P. (1975) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365517509095787 · Cited by 1,173

Flagged first, then by citations

Show all 51 references

1 of the 51 references couldn’t be matched to a known paper.

Sorted by citations

Items 101–200 of 487

Tissue-Engineered Skeletal Muscle Models to Study Muscle Function, Plasticity, and Disease
Khodabukus, A. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.619710 · Cited by 92
Elevated SOCS3 and altered IL-6 signaling is associated with age-related human muscle stem cell dysfunction
McKay, B. R., Ogborn, D. I., Baker, J. M., Toth, K., Tarnopolsky, M. A., & Parise, G. (2013) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00305.2012 · Cited by 87
Pax7 Reveals a Greater Frequency and Concentration of Satellite Cells at the Ends of Growing Skeletal Muscle Fibers
Allouh, M. Z., Yablonka‐Reuveni, Z., & Rosser, B. W. C. (2007) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.7a7301.2007 · Cited by 83
The critical role of oxidative stress in sarcopenic obesity
Gonzalez, A., Simon, F., Achiardi, O., Vilos, C., Cabrera, D., & Cabello-Verrugio, C. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/4493817 · Cited by 79
Proteomics of muscle chronological ageing in post-menopausal women
Gueugneau, M., Coudy‐Gandilhon, C., Gourbeyre, O., Chambon, C., Combaret, L., Polge, C., Taillandier, D., Attaix, D., Friguet, B., Maier, A. B., et al. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-1165 · Cited by 82
Satellite cell number and cell cycle kinetics in response to acute myotrauma in humans: immunohistochemistryversusflow cytometry
McKay, B. R., Toth, K., Tarnopolsky, M. A., & Parise, G. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.190876 · Cited by 83
Importance of Lean Body Mass in the Oncologic Patient
Tsai, S. (2012) · Nutrition in Clinical Practice · doi:10.1177/0884533612457949 · Cited by 83
Acute low-load resistance exercise with and without blood flow restriction increased protein signalling and number of satellite cells in human skeletal muscle
Wernbom, M., Apró, W., Paulsen, G., Nilsen, T. S., Blomstrand, E., & Raastad, T. (2013) · European Journal of Applied Physiology · doi:10.1007/s00421-013-2733-5 · Cited by 80
Genes and the ageing muscle: a review on genetic association studies
Garatachea, N., & Lucía, A. (2011) · AGE · doi:10.1007/s11357-011-9327-0 · Cited by 79
Identification of morphological markers of sarcopenia at early stage of aging in skeletal muscle of mice
Sayed, R. K. A., de Leonardis, E. C., Guerrero-Martinez, J. A., Rahim, I., Mokhtar, D. M., Saleh, A. M., Abdalla, K. E. H., Pozo, M. J., Escames, G., López, L. C., et al. (2016) · Experimental Gerontology · doi:10.1016/j.exger.2016.07.007 · Cited by 81
Maintenance of Skeletal Muscle to Counteract Sarcopenia in Patients with Advanced Chronic Kidney Disease and Especially Those Undergoing Hemodialysis
Mori, K. (2021) · Nutrients · doi:10.3390/nu13051538 · Cited by 86
The Role of Satellite Cells in Skeletal Muscle Regeneration—The Effect of Exercise and Age
Kaczmarek, A., Kaczmarek, M., Ciałowicz, M., Clemente, F. M., Wolański, P. M., Bădicu, G., & Murawska‐Ciałowicz, E. (2021) · Biology · doi:10.3390/biology10101056 · Cited by 87
The role of satellite cells in muscle hypertrophy
Blaauw, B., & Reggiani, C. (2014) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-014-9376-y · Cited by 90
Genes, physical fitness and ageing
Garatachea, N., & Lucía, A. (2012) · Ageing Research Reviews · doi:10.1016/j.arr.2012.09.003 · Cited by 84
The influence of capillarization on satellite cell pool expansion and activation following exercise‐induced muscle damage in healthy young men
Nederveen, J. P., Joanisse, S., Snijders, T., Thomas, A. C. Q., Kumbhare, D. A., & Parise, G. (2018) · The Journal of Physiology · doi:10.1113/jp275155 · Cited by 81
Central and Peripheral Neuromuscular Adaptations to Ageing
Borzuola, R., Giombini, A., Torre, G., Campi, S., Albo, E., Bravi, M., Borrione, P., FOSSATI, C., & Macaluso, A. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9030741 · Cited by 91
Is the myonuclear domain size fixed?
van der Meer, S. F. T., Jaspers, R. T., & Degens, H. (2011) · PubMed · Cited by 78
Heterogeneity of quadriceps muscle phenotype in chronic obstructive pulmonary disease ( Copd ); implications for stratified medicine?
Natanek, S. A., Gosker, H. R., Slot, I. G. M., Marsh, G. S., Hopkinson, N. S., Man, W. D., Tal‐Singer, R., Moxham, J., Kemp, P. R., Schols, A. M. W. J., et al. (2013) · Muscle & Nerve · doi:10.1002/mus.23784 · Cited by 80
Sarcopenia, a Neurogenic Syndrome?
Kwan, P. (2013) · Journal of Aging Research · doi:10.1155/2013/791679 · Cited by 77
Muscle disuse atrophy is not accompanied by changes in skeletal muscle satellite cell content
Snijders, T., Wall, B. T., Dirks, M. L., Senden, J. M., Hartgens, F., Dolmans, J., Losen, M. H., Verdijk, L. B., & van Loon, L. J. C. (2013) · Clinical Science · doi:10.1042/cs20130295 · Cited by 82
Self-citation
New multiple labelling method for improved satellite cell identification in human muscle: application to a cohort of power-lifters and sedentary men
Lindström, M., & Thornell, L. (2009) · Histochemistry and Cell Biology · doi:10.1007/s00418-009-0606-0 · Cited by 77
Potential roles of vitamin E in age-related changes in skeletal muscle health
Chung, E., Mo, H., Wang, S. F., Zu, Y., Elfakhani, M., Rios, S. R., Chyu, M.-C., Yang, R., & Shen, C. (2017) · Nutrition Research · doi:10.1016/j.nutres.2017.09.005 · Cited by 74
Age modifies respiratory complex I and protein homeostasis in a muscle type‐specific manner
Kruse, S. E., Karunadharma, P. P., Basisty, N., Johnson, R. S., Beyer, R. P., MacCoss, M. J., Rabinovitch, P. S., & Marcinek, D. J. (2015) · Aging Cell · doi:10.1111/acel.12412 · Cited by 73
Extensive Type II Muscle Fiber Atrophy in Elderly Female Hip Fracture Patients
Kramer, I. F., Snijders, T., Smeets, J. S. J., Leenders, M., van Kranenburg, J. M. X., den Hoed, M., Verdijk, L. B., Poeze, M., & van Loon, L. J. C. (2017) · The Journals of Gerontology Series A · doi:10.1093/gerona/glw253 · Cited by 77
Self-citation
An aPPARent functional consequence in skeletal muscle physiology via peroxisome proliferator-activated receptors
Phua, W. W. T., Wong, M. X. Y., Liao, Z., & Tan, N. S. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19051425 · Cited by 72
Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging
Crupi, A. N., Nunnelee, J. S., Taylor, D. J., Thomas, A., Vit, J., Riera, C. E., Gottlieb, R. A., & Goodridge, H. S. (2018) · Aging · doi:10.18632/aging.101643 · Cited by 72
Changes in Redox Signaling in the Skeletal Muscle with Aging
Szentesi, P., Csernoch, L., Dux, L., & Keller-Pintér, A. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/4617801 · Cited by 71
Exercise training as S-Klotho protein stimulator in sedentary healthy adults: Rationale, design, and methodology
Amaro‐Gahete, F. J., De‐la‐O, A., Jurado‐Fasoli, L., Espuch-Oliver, A., Robles‐González, L., Navarro‐Lomas, G., de Haro, T., Femia, P., Castillo, M. J., & Gutiérrez, Á. (2018) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2018.05.013 · Cited by 78
Vitamin D Signaling in Myogenesis: Potential for Treatment of Sarcopenia
Wagatsuma, A., & Sakuma, K. (2014) · BioMed Research International · doi:10.1155/2014/121254 · Cited by 73
'Protein Supplementation after Exercise and before Sleep Does Not Further Augment Muscle Mass and Strength Gains during Resistance Exercise Training in Active Older Men
Holwerda, A. M., Overkamp, M., Paulussen, K. J. M., Smeets, J. S. J., van Kranenburg, J. M. X., Backx, E. M. P., Gijsen, A. P., Goessens, J. P. B., Verdijk, L. B., & van Loon, L. J. C. (2018) · Journal of Nutrition · doi:10.1093/jn/nxy169 · Cited by 80
Self-citation
Impact of viral-mediated IGF-I gene transfer on skeletal muscle following cast immobilization
Stevens‐Lapsley, J. E., Ye, F., Liu, M., Borst, S. E., Conover, C. F., Yarasheski, K. E., Walter, G. A., Sweeney, H. L., & Vandenborne, K. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00230.2010 · Cited by 71
Factors influencing pacing in triathlon
Wu, S. S. X., Abbiss, C. R., Peiffer, J. J., Brisswalter, J., & Nosaka, K. (2014) · Open Access Journal of Sports Medicine · doi:10.2147/oajsm.s44392 · Cited by 70
Lack of muscle fibre hypertrophy, myonuclear addition, and satellite cell pool expansion with resistance training in 83‐94‐year‐old men and women
Karlsen, A., Bechshøft, R. L., Malmgaard‐Clausen, N. M., Andersen, J. L., Schjerling, P., Kjær, M., & Mackey, A. L. (2019) · Acta Physiologica · doi:10.1111/apha.13271 · Cited by 73
Impact of Aging on Endurance and Neuromuscular Physical Performance: The Role of Vascular Senescence
Mendonça, G. V., Pezarat‐Correia, P., Vaz, J. R., Silva, L., & Heffernan, K. S. (2016) · Sports Medicine · doi:10.1007/s40279-016-0596-8 · Cited by 78
Structural and Functional Changes in the Coupling of Fascial Tissue, Skeletal Muscle, and Nerves During Aging
Zullo, A., Fleckenstein, J., Schleip, R., Hoppe, K., Wearing, S. C., & Klingler, W. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00592 · Cited by 73
Efficacy and safety of pharmacological agents in managing osteoporosis in the old old: Review of the evidence
Inderjeeth, C. A., Foo, A. C. H., Lai, M. M. Y., & Glendenning, P. (2008) · Bone · doi:10.1016/j.bone.2008.12.003 · Cited by 67
Lipotoxicity, aging, and muscle contractility: does fiber type matter?
Carter, C. S., Justice, J. N., & Thompson, L. (2019) · GeroScience · doi:10.1007/s11357-019-00077-z · Cited by 66
Role of microRNAs in the age-related changes in skeletal muscle and diet or exercise interventions to promote healthy aging in humans
McGregor, R. A., Poppitt, S. D., & Cameron‐Smith, D. (2014) · Ageing Research Reviews · doi:10.1016/j.arr.2014.05.001 · Cited by 66
Altered muscle satellite cell activation following 16 wk of resistance training in young men
Nederveen, J. P., Snijders, T., Joanisse, S., Wavell, C. G., Mitchell, C. J., Johnston, L. M., Baker, S. K., Phillips, S. M., & Parise, G. (2016) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00221.2016 · Cited by 65
Human muscle satellite cells show age-related differential expression of S100B protein and RAGE
Beccafico, S., Riuzzi, F., Puglielli, C., Mancinelli, R., Fulle, S., Sorci, G., & Donato, R. (2010) · AGE · doi:10.1007/s11357-010-9197-x · Cited by 66
A single bout of exercise activates skeletal muscle satellite cells during subsequent overnight recovery
Snijders, T., Verdijk, L. B., Beelen, M., McKay, B. R., Parise, G., Kadi, F., & van Loon, L. J. C. (2012) · Experimental Physiology · doi:10.1113/expphysiol.2011.063313 · Cited by 66
Self-citation
Differential satellite cell density of type I and II fibres with lifelong endurance running in old men
Mackey, A. L., Karlsen, A., Couppé, C., Mikkelsen, U. R., Nielsen, R. H., Magnusson, S. P., & Kjær, M. (2013) · Acta Physiologica · doi:10.1111/apha.12195 · Cited by 63
Creatine Loading Does not Preserve Muscle Mass or Strength during Leg Immobilization in Healthy, Young Males: A Randomized Controlled Trial
Backx, E. M. P., Hangelbroek, R., Snijders, T., Verscheijden, M.-L., Verdijk, L. B., de Groot, L. C. P. G. M., & van Loon, L. J. C. (2017) · Sports Medicine · doi:10.1007/s40279-016-0670-2 · Cited by 61
Self-citation
Advanced Glycation End-Products in Skeletal Muscle Aging
Olson, L. C., Redden, J. T., Schwartz, Z., Cohen, D. J., & McClure, M. J. (2021) · Bioengineering · doi:10.3390/bioengineering8110168 · Cited by 66
PAX7+ satellite cells in young and older adults following resistance exercise
Walker, D. K., Fry, C. S., Drummond, M. J., Dickinson, J. M., Timmerman, K. L., Gundermann, D. M., Jennings, K., Volpi, E., & Rasmussen, B. B. (2011) · Muscle & Nerve · doi:10.1002/mus.23266 · Cited by 58
Inflammatory and Satellite Cells in the Quadriceps of Patients With COPD and Response to Resistance Training
Menon, M. K., Houchen, L., Singh, S. J., Morgan, M. D. L., Bradding, P. H., & STEINER, M. C. (2012) · CHEST Journal · doi:10.1378/chest.11-2144 · Cited by 57
Skeletal Muscle Function Deficits in the Elderly: Current Perspectives on Resistance Training.
Papa, E. V., Dong, X., & Hassan, M. (2017) · PubMed · Cited by 57
NMR based biomarkers to study age-related changes in the human quadriceps
Azzabou, N., Hogrel, J., & Carlier, P. G. (2015) · Experimental Gerontology · doi:10.1016/j.exger.2015.06.015 · Cited by 57
Effect of ractopamine-hydrochloride and trenbolone acetate on longissimus muscle fiber area, diameter, and satellite cell numbers in cull beef cows1
Gonzalez, J. M., Carter, J. N., Johnson, D. D., Ouellette, S. E., & Johnson, S. E. (2007) · Journal of Animal Science · doi:10.2527/jas.2006-624 · Cited by 57
Dietary protein considerations to support active aging
Wall, B. T., Cermak, N. M., & van Loon, L. J. C. (2014) · Sports Medicine · doi:10.1007/s40279-014-0258-7 · Cited by 56
Protein Supplementation Augments Muscle Fiber Hypertrophy but Does Not Modulate Satellite Cell Content During Prolonged Resistance-Type Exercise Training in Frail Elderly
Dirks, M. L., Tieland, M., Verdijk, L. B., Losen, M., Nilwik, R., Mensink, M., de Groot, L. C. P. G. M., & van Loon, L. J. C. (2017) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2017.02.006 · Cited by 56
Novel Intriguing Strategies Attenuating to Sarcopenia
Sakuma, K., & Yamaguchi, A. (2012) · Journal of Aging Research · doi:10.1155/2012/251217 · Cited by 59
Patterns of Age-Associated Degeneration Differ in Shoulder Muscles
Raz, Y., Henseler, J. F., Kolk, A., Riaz, M., van der Zwaal, P., Nagels, J., Nelissen, R. G. H. H., & Raz, V. (2015) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2015.00236 · Cited by 56
Effects of strength training and detraining on regional muscle in young and older men and women
Melnyk, J. A., Rogers, M. A., & Hurley, B. F. (2009) · European Journal of Applied Physiology · doi:10.1007/s00421-008-0979-0 · Cited by 56
Aging Changes in Satellite Cells and Their Functions
Hikida, R. S. (2011) · Current Aging Science · doi:10.2174/1874609811104030279 · Cited by 55
Sarcopenia: current theories and the potential beneficial effect of creatine application strategies
Candow, D. G. (2011) · Biogerontology · doi:10.1007/s10522-011-9327-6 · Cited by 53
Sarcopenic Dysphagia. A Narrative Review
Dellis, S., Papadopoulou, S. L., Krikonis, K., & Zigras, F. (2018) · Journal of Frailty Sarcopenia and Falls · doi:10.22540/jfsf-03-001 · Cited by 53
Sarcopenia: Molecular regulatory network for loss of muscle mass and function
Wu, J., Ding, P., Wu, H., Yang, P., Guo, H., Tian, Y., Meng, L., & Zhao, Q. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1037200 · Cited by 55
Up-regulation of calcium-dependent proteolysis in human myoblasts under acute oxidative stress
Dargelos, É., Brulé, C., Stuelsatz, P., Mouly, V., Veschambre, P., Cottin, P., & Poussard, S. (2009) · Experimental Cell Research · doi:10.1016/j.yexcr.2009.07.025 · Cited by 53
Strength training increases the size of the satellite cell pool in type I and II fibres of chronically painful trapezius muscle in females
Mackey, A. L., Andersen, L. L., Frandsen, U., & Sjøgaard, G. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.217885 · Cited by 54
Factors associated with masseter muscle quality assessed from ultrasonography in community-dwelling elderly individuals: A cross-sectional study
Yamaguchi, K., Tohara, H., Hara, K., Nakane, A., Yoshimi, K., Nakagawa, K., & Minakuchi, S. (2019) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2019.02.003 · Cited by 53
Inflamma-miR-21 Negatively Regulates Myogenesis during Ageing
Borja-Gonzalez, M., Casas-Martinez, J. C., McDonagh, B., & Goljanek‐Whysall, K. (2020) · Antioxidants · doi:10.3390/antiox9040345 · Cited by 56
Regulation of Satellite Cells Functions during Skeletal Muscle Regeneration: A Critical Step in Physiological and Pathological Conditions
Careccia, G., Mangiavini, L., & Cirillo, F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010512 · Cited by 66
Mitochondrial function in skeletal myofibers is controlled by a TRF2‐SIRT3 axis over lifetime
Robin, J. D., Burbano, M. S. J., Peng, H., Croce, O., Thomas, J. L., Laberthonnìère, C., Renault, V. M., Lototska, L., Pousse, M., Tessier, F., et al. (2020) · Aging Cell · doi:10.1111/acel.13097 · Cited by 58
Dietary protein and exercise training in ageing
Koopman, R. (2011) · Proceedings of The Nutrition Society · doi:10.1017/s0029665110003927 · Cited by 50
Self-citation
The effect of exercise mode on the acute response of satellite cells in old men
Nederveen, J. P., Joanisse, S., Séguin, C., Bell, K. E., Baker, S. K., Phillips, S. M., & Parise, G. (2015) · Acta Physiologica · doi:10.1111/apha.12601 · Cited by 52
Ursolic acid ameliorates aging-metabolic phenotype through promoting of skeletal muscle rejuvenation
Bakhtiari, N., Hosseinkhani, S., Tashakor, A., & Hemmati, R. (2015) · Medical Hypotheses · doi:10.1016/j.mehy.2015.02.014 · Cited by 51
Early-Phase Adaptations to a Split-Body, Linear Periodization Resistance Training Program in College-Aged and Middle-Aged Men
Kerksick, C. M., Wilborn, C., Campbell, B. I., Roberts, M. D., Rasmussen, C. J., Greenwood, M. P., & Kreider, R. B. (2009) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0b013e3181a00baf · Cited by 49
Iron accumulation causes impaired myogenesis correlated with MAPK signaling pathway inhibition by oxidative stress
Ikeda, Y., Satoh, A., Horinouchi, Y., Hamano, H., Watanabe, H., Imao, M., Imanishi, M., Zamami, Y., Takechi, K., Izawa‐Ishizawa, Y., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201802724rr · Cited by 50
Time‐course of changes in the myonuclear domain during denervation in young‐adult and old rat gastrocnemius muscle
van der Meer, S. F. T., Jaspers, R. T., Jones, D. A., & Degens, H. (2011) · Muscle & Nerve · doi:10.1002/mus.21822 · Cited by 48
Short-Term Heavy Resistance Training Eliminates Age-Related Deficits in Muscle Mass and Strength in Healthy Older Males
Candow, D. G., Chilibeck, P. D., Abeysekara, S., & Zello, G. A. (2010) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0b013e3181bf43c8 · Cited by 48
Myosin Heavy Chain Plasticity in Aging Skeletal Muscle With Aerobic Exercise Training
Konopka, A. R., Trappe, T. A., Jemioło, B., Trappe, S. W., & Harber, M. P. (2011) · The Journals of Gerontology Series A · doi:10.1093/gerona/glr088 · Cited by 48
Human myotubes from myoblast cultures undergoing senescence exhibit defects in glucose and lipid metabolism
Nehlin, J. O., Just, M., Rustan, A. C., & Gaster, M. (2011) · Biogerontology · doi:10.1007/s10522-011-9336-5 · Cited by 53
Nuclei of aged myofibres undergo structural and functional changes suggesting impairment in RNA processing
Malatesta, M., Perdoni, F., Muller, S., Zancanaro, C., & Pellicciari, C. (2009) · European Journal of Histochemistry · doi:10.4081/ejh.2009.e12 · Cited by 48
Leucine Supplementation Does Not Attenuate Skeletal Muscle Loss during Leg Immobilization in Healthy, Young Men
Backx, E. M. P., Horstman, A. M. H., Marzuca-Nassr, G. N., van Kranenburg, J. M. X., Smeets, J. S. J., Fuchs, C. J., Janssen, A. A. W., de Groot, C. P. G. M., Snijders, T., Verdijk, L. B., et al. (2018) · Nutrients · doi:10.3390/nu10050635 · Cited by 49
Self-citation
Ageing has no effect on the regulation of the ubiquitin proteasome-related genes and proteins following resistance exercise
Stefanetti, R. J., Zacharewicz, E., Gatta, P. A. D., GARNHAM, A. P., Russell, A. P., & Lamon, S. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00030 · Cited by 48
Role of exercise in estrogen deficiency-induced sarcopenia
Cho, E., Choi, Y., Jung, S., & Kwak, H. (2022) · Journal of Exercise Rehabilitation · doi:10.12965/jer.2244004.002 · Cited by 49
Isolation, characterization, and molecular regulation of muscle stem cells
Fukada, S., Ma, Y., Ohtani, T., Watanabe, Y., Murakami, S., & Yamaguchi, M. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00317 · Cited by 48
Botulinum Toxin Induced Atrophy: An Uncharted Territory
Salari, M., Sharma, S., & Jog, M. (2018) · Toxins · doi:10.3390/toxins10080313 · Cited by 45
Superior Aerobic Capacity and Indices of Skeletal Muscle Morphology in Chronically Trained Master Endurance Athletes Compared With Untrained Older Adults
McKendry, J., Joanisse, S., Baig, S., Liu, B., Parise, G., Greig, C. A., & Breen, L. (2019) · The Journals of Gerontology Series A · doi:10.1093/gerona/glz142 · Cited by 46
Influence of sex and fiber type on the satellite cell pool in human skeletal muscle
Horwath, O., Moberg, M., Larsen, F. J., Philp, A., Apró, W., & Ekblom, B. T. (2020) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.13848 · Cited by 44
Improving maternal vitamin D status promotes prenatal and postnatal skeletal muscle development of pig offspring
Zhou, H., Chen, Y., Lv, G., Zhuo, Y., Lin, Y., Feng, B., Fang, Z., Che, L., Li, J., Xu, S., et al. (2016) · Nutrition · doi:10.1016/j.nut.2016.03.004 · Cited by 43
Ageing leads to selective type II myofibre deterioration and denervation independent of reinnervative capacity in human skeletal muscle
Horwath, O., Moberg, M., Edman, S., Philp, A., & Apró, W. (2024) · Experimental Physiology · doi:10.1113/ep092222 · Cited by 41
Physiological and pathological skeletal muscle T1 changes quantified using a fast inversion-recovery radial NMR imaging sequence
Marty, B., & Carlier, P. G. (2019) · Scientific Reports · doi:10.1038/s41598-019-43398-x · Cited by 42
Myonuclear permanence in skeletal muscle memory: a systematic review and meta‐analysis of human and animal studies
Rahmati, M., McCarthy, J. J., & Malakoutinia, F. (2022) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13043 · Cited by 41
Age-related sex differences in erector spinae muscle endurance using surface electromyographic power spectral analysis in healthy humans
Tsuboi, H., Nishimura, Y., Sakata, T., Ohko, H., Tanina, H., Kouda, K., Nakamura, T., Umezu, Y., & Tajima, F. (2013) · The Spine Journal · doi:10.1016/j.spinee.2013.06.060 · Cited by 41
Effects of age on human skeletal muscle: a systematic review and meta-analysis of myosin heavy chain isoform protein expression, fiber size, and distribution
Lee, C., Woods, P. C., Paluch, A. E., & Miller, M. S. (2024) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00347.2024 · Cited by 45
Active muscle regeneration following eccentric contraction-induced injury is similar between healthy young and older adults
Buford, T. W., MacNeil, R. G., Clough, L. G., Dirain, M. L. S., Sandesara, B. D., Pahor, M., Manini, T. M., & Leeuwenburgh, C. (2013) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01350.2012 · Cited by 40
Long-lived crowded-litter mice have an age-dependent increase in protein synthesis to DNA synthesis ratio and mTORC1 substrate phosphorylation
Drake, J. C., Bruns, D. R., Peelor, F. F., Biela, L. M., Miller, R. A., Hamilton, K. L., & Miller, B. F. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00256.2014 · Cited by 39
Short-term ursolic acid promotes skeletal muscle rejuvenation through enhancing of SIRT1 expression and satellite cells proliferation
Bakhtiari, N., Hosseinkhani, S., Soleimani, M., Hemmati, R., Noori-Zadeh, A., Javan, M., & Tashakor, A. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.01.010 · Cited by 40
Nutmeg Extract Increases Skeletal Muscle Mass in Aging Rats Partly via IGF1‐AKT‐mTOR Pathway and Inhibition of Autophagy
Pratiwi, Y. S., Lesmana, R., Goenawan, H., Sylviana, N., Setiawan, I. B., Tarawan, V. M., Lestari, K., Abdulah, R., Dwipa, L., Purba, A., et al. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/2810840 · Cited by 40
Skeletal muscle mitochondria in health and disease
Mario, A. D., Gherardi, G., Rizzuto, R., & Mammucari, C. (2021) · Cell Calcium · doi:10.1016/j.ceca.2021.102357 · Cited by 42
Musculoskeletal ageing and primary prevention
Nedergaard, A., Henriksen, K., Karsdal, M. A., & Christiansen, C. (2013) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2013.06.001 · Cited by 42
Neural and musculotendinous mechanisms underpinning age-related force reductions
Orssatto, L. B. R., Wiest, M. J., & Diefenthaeler, F. (2018) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2018.06.005 · Cited by 55
Distribution of myogenic progenitor cells and myonuclei is altered in women with vs. those without chronically painful trapezius muscle
Mackey, A. L., Andersen, L. L., Frandsen, U., Suetta, C., & Sjøgaard, G. (2010) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00789.2010 · Cited by 39
Continuous endurance-type exercise training does not modulate satellite cell content in obese type 2 diabetes patients.
Snijders, T., Verdijk, L. B., Hansen, D., Dendale, P., & van Loon, L. J. C. (2011) · Muscle & Nerve · doi:10.1002/mus.21891 · Cited by 37
Self-citation
Large‐scale isolation of human skeletal muscle satellite cells from post‐mortem tissue and development of quantitative assays to evaluate modulators of myogenesis
Scott, I. C., Tomlinson, W., Walding, A., Isherwood, B. J., & Dougall, I. G. (2013) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1007/s13539-012-0097-z · Cited by 37
Troponin T nuclear localization and its role in aging skeletal muscle
Zhang, T., Birbrair, A., Wang, Z., Taylor, J. R., Messi, M. L., & Delbono, O. (2011) · AGE · doi:10.1007/s11357-011-9368-4 · Cited by 37
Lactate Activates AMPK Remodeling of the Cellular Metabolic Profile and Promotes the Proliferation and Differentiation of C2C12 Myoblasts
Zhou, Y., Liu, X., Huang, C., & Lin, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232213996 · Cited by 36
Satellite cell therapy – from mice to men
Bareja, A., & Billin, A. N. (2013) · Skeletal Muscle · doi:10.1186/2044-5040-3-2 · Cited by 35

Authors: Verdijk, L. B., Koopman, R., Schaart, G., Meijer, K., Savelberg, H. H. C. M., & van Loon, L. J. C.
Affiliations: Maastricht University (NL)
ORCID: Verdijk, Lex B.
Koopman, René
Schaart, Gert
Meijer, Kenneth
Savelberg, Hans H. C. M.
Venue: American Journal of Physiology-Endocrinology and Metabolism
Publisher: American Physiological Society
Published: 2007-01
Volume: 292
Issue: 1
Pages: E151-E157
ISSN: 0193-1849 (ISSN-L)
1522-1555
DOI: 10.1152/ajpendo.00278.2006
OpenAlex: W2113612408
Cited by: 489
References: 51
Citations by year: 2026: 14 · 2025: 17 · 2024: 21 · 2023: 20 · 2022: 35 · 2021: 33 · 2020: 27 · 2019: 27 · 2018: 35 · 2017: 25 · 2016: 28 · 2015: 28 · 2014: 35 · 2013: 36 · 2012: 27
FWCI: 4.48
Type: journal article
Language: en
Open access: green
cris.maastrichtuniversity.nl
Licence: other-oa
Locations: American Journal of Physiology-Endocrinology and Metabolism (publishedVersion)
PubMed (publishedVersion)
Research Publications (Maastricht University) (submittedVersion, other-oa)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
Keywords: satellite cells, sarcopenia, muscle atrophy, aging, older adults, Pax7, vastus lateralis, muscle fiber cross-sectional area
MeSH terms: Adult, Aged, Atrophy, Biopsy, Cell Count, Cell Nucleus, Humans, Male, Muscle Fibers, Fast-Twitch, Satellite Cells, Skeletal Muscle

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks