CoChat
Sign Up
Cited by 375Dementia and Cognitive Impairment ResearchPsychological Testing and AssessmentHistorical and Modern Theater Studies

The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.

Early Detection and Differential Diagnosis of Alzheimer’s Disease and Depression with Neuropsychological Tasks

Swainson, R., Hodges, J.R., Galton, C.J., Semple, J., Michael, A., Dunn, B.D., Iddon, J.L., Robbins, T.W., Sahakian, B.J.·2001·Dementia and Geriatric Cognitive Disorders
DOI 10.1159/000051269
Open this paper in CoChat — free account

Abstract

The development of novel treatments for Alzheimer’s disease (AD), aimed at ameliorating symptoms and modifying disease processes, increases the need for early diagnosis. Neuropsychological deficits such as poor episodic memory are a consistent feature of early-in-the-course AD, but they overlap with the cognitive impairments in other disorders such as depression, making differential diagnosis difficult. Computerised and traditional tests of memory, attention and executive function were given to four subject groups: mild AD (n = 26); questionable dementia (QD; n = 43); major depression (n = 37) and healthy controls (n = 39). A visuo-spatial associative learning test accurately distinguished AD from depressed/control subjects and revealed an apparent sub-group of QD patients who performed like AD patients. QD patients’ performance correlated with the degree of subsequent global cognitive decline. Elements of contextual and cued recall may account for the task’s sensitivity and specificity for AD.

Overview

Integrity signals

Registry

Crossref · 10.1159/000051269

Cites

66 of 66 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 2

  1. 10.1037//0735-7044.107.1.3 · DOI · Paper page
  2. 10.1037//0894-4105.9.1.126 · DOI

Cited by

Sorted by citations

See all 375

Related

See all

Metadata

Authors
Swainson, R., Hodges, J. R., Galton, C. J., Semple, J., Michael, A., Dunn, B. D., Iddon, J. L., Robbins, T. W., & Sahakian, B. J.
Affiliations
  • University of Cambridge (GB)
  • Addenbrooke's Hospital (GB)
  • West Suffolk Hospital (GB)
ORCID
Venue
Dementia and Geriatric Cognitive Disorders
Publisher
S. Karger AG
Published
2001
Volume
12
Issue
4
Pages
265-280
ISSN
  • 1420-8008 (ISSN-L)
  • 1421-9824
DOI
10.1159/000051269
OpenAlex
W1980584599
Cited by
375
References
65
Citations by year
2026: 4 · 2025: 6 · 2024: 14 · 2023: 8 · 2022: 7 · 2021: 9 · 2020: 14 · 2019: 17 · 2018: 12 · 2017: 17 · 2016: 20 · 2015: 19 · 2014: 21 · 2013: 22 · 2012: 18
FWCI
8.37
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Dementia and Geriatric Cognitive Disorders (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
  • Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
Keywords
Alzheimer's disease, depression, differential diagnosis, early detection, episodic memory, cognitive decline, cued recall, neuropsychological assessment
MeSH terms
Aged, Alzheimer Disease, Analysis of Variance, Dementia, Major Depressive Disorder, Diagnosis, Differential, Female, Humans, Male, Memory, Middle Aged, Neuropsychological Tests, Predictive Value of Tests, Logistic Models, Case-Control Studies

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review