Cited by 305Cardiovascular Health and Risk FactorsHealthcare Systems and Public HealthHealth Promotion and Cardiovascular Prevention

Factors Predictive of Long-Term Coronary Heart Disease Mortality among 10,059 Male Israeli Civil Servants and Municipal Employees

Goldbourt, Uri, Yaari, Shlomit, Medalie, Jack H.·2008·Cardiology

Abstract

Over 10,000 male civil servants and municipal employees in Israel, aged 40 years and above, underwent an extensive clinical, biochemical, anthropometric, sociodemographic and psychosocial evaluation in 1963, 1965 and 1968. Follow-up for mortality was continued through 1986. Over 23 years, a number of previously established risk factors for coronary heart disease (CHD) incidence were found to predict mortality. The long-term follow-up assisted in illustrating temporal patterns. A single casual assessment of blood pressure retained high prediction for long-term mortality. Blood lipids, while significantly associated with both coronary and all-cause mortality, exhibited a small contribution to the latter, when compared to hypertension, cigarette smoking habits and diabetes. Weak associations of long-term coronary mortality with the dietary intake patterns of fatty acids, as reported at baseline, were probably fully mediated by the effect of the diet on serum cholesterol. Religious orthodoxy appeared to provide a degree of immunity, part of which was independent of life-style correlates. A number of now well-established associations in cardiovascular epidemiology were first demonstrated, or amplified, in the study. Patterns of ethnic diversity in the risk factor and prevalence rates of CHD persisted, as viewed from the angle of mortality rates, over nearly a quarter of a decade, highlighting the enigma of a migrant country as a cardiovascular melting pot.

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Crossref · 10.1159/000175862

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Authors
Goldbourt, U., Yaari, S., & Medalie, J. H.
Affiliations
  • Tel Aviv University (IL)
  • Bar-Ilan University (IL)
  • Case Western Reserve University (US)
Venue
Cardiology
Publisher
S. Karger AG
Published
2008-11-14
Volume
82
Issue
2-3
Pages
100-121
ISSN
  • 0008-6312 (ISSN-L)
  • 1421-9751
OpenAlex
W2069442178
Cited by
304
References
0
Citations by year
2026: 1 · 2025: 1 · 2024: 5 · 2023: 44 · 2022: 4 · 2021: 5 · 2020: 4 · 2019: 3 · 2018: 6 · 2017: 1 · 2016: 5 · 2015: 10 · 2014: 6 · 2013: 9 · 2012: 5
FWCI
10.87
Type
journal article
Language
en
Open access
closed
Locations
  • Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
Keywords
coronary heart disease mortality, cardiovascular risk factors, blood pressure, serum lipids, serum cholesterol, cigarette smoking, diabetes mellitus, dietary fatty acids, religious orthodoxy, ethnic diversity, public sector employees, municipal employees, long-term follow-up
MeSH terms
Adult, Aged, Blood Pressure, Cholesterol, Coronary Disease, Cross-Cultural Comparison, Emigration and Immigration, Feeding Behavior, Follow-Up Studies, Humans, Israel, Jews, Male, Middle Aged, Local Government, Prospective Studies, Religion and Medicine, Risk Factors, Survival Rate, Multivariate Analysis

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