Mindfulness-Based Cognitive Therapy Improves Polysomnographic and Subjective Sleep Profiles in Antidepressant Users with Sleep Complaints
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BACKGROUND: Many antidepressant medications (ADM) are associated with disruptions in sleep continuity that can compromise medication adherence and impede successful treatment. The present study investigated whether mindfulness meditation (MM) training could improve self-reported and objectively measured polysomnographic (PSG) sleep profiles in depressed individuals who had achieved at least partial remission with ADM, but still had residual sleep complaints. METHODS: Twenty-three ADM users with sleep complaints were randomized into an 8-week Mindfulness-Based Cognitive Therapy (MBCT) course or a waitlist control condition. Pre-post measurements included PSG sleep studies and subjectively reported sleep, residual depression symptoms. RESULTS: Compared to controls, the MBCT participants improved on both PSG and subjective measures of sleep. They showed a pattern of decreased wake time and increased sleep efficiency. Sleep depth, as measured by stage 1 and slow-wave sleep, did not change as a result of mindfulness training. CONCLUSIONS: MM is associated with increases in both objectively and subjectively measured sleep continuity in ADM users. MM training may serve as more desirable and cost-effective alternative to discontinuation or supplementation with hypnotics, and may contribute to a more sustainable recovery from depression.
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Controlled trial evidence supports the use of mind-body interventions for sleep disturbances in adults.
“Indeed, controlled trial evidence provides support for the use of mind-body interventions for sleep disturbances in adults (Andersen et al, 2013;Britton et al, 2012)”
From Sleep health: Reciprocal regulation of sleep and innate immunity (2017) · cites this paper as Britton et al, 2012
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- Authors
- Britton, W. B., Haynes, P. L., Fridel, K. W., & Bootzin, R. R.
- Affiliations
- Brown University (US)
- University of Arizona (US)
- Venue
- Psychotherapy and Psychosomatics
- Publisher
- S. Karger AG
- Published
- 2012
- Volume
- 81
- Issue
- 5
- Pages
- 296-304
- ISSN
- 0033-3190 (ISSN-L)
- 1423-0348
- PMC
- PMC3495555
- OpenAlex
- W2081594108
- Cited by
- 81
- References
- 78
- Citations by year
- 2026: 7 · 2025: 6 · 2024: 5 · 2023: 3 · 2022: 7 · 2021: 6 · 2020: 1 · 2019: 5 · 2018: 4 · 2017: 8 · 2016: 7 · 2015: 10 · 2014: 5 · 2013: 7
- FWCI
- 7.98
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychotherapy and Psychosomatics (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (T32MH067553, MH067553-05)
- National Center for Complementary and Integrative Health (T32AT001287, K23AT006328)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- mindfulness-based cognitive therapy, mindfulness meditation, antidepressants, sleep complaints, sleep continuity, polysomnography, sleep efficiency, wake time, slow-wave sleep, depression remission
- MeSH terms
- Adult, Analysis of Variance, Antidepressive Agents, Depressive Disorder, Female, Humans, Sleep Initiation and Maintenance Disorders, Male, Middle Aged, Psychiatric Status Rating Scales, Recurrence, Cognitive Behavioral Therapy, Outcome Assessment, Health Care, Polysomnography, Meditation
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