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Cell-Autonomous Role of Endothelial GTP Cyclohydrolase 1 and Tetrahydrobiopterin in Blood Pressure Regulation

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Impaired intestinal immune barrier and physical barrier function by phosphorus deficiency: Regulation of TOR, NF-κB, MLCK, JNK and Nrf2 signalling in grass carp (Ctenopharyngodon idella) after infection with Aeromonas hydrophila

Chen, K., Zhou, X., Jiang, W., Wu, P., Liu, Y., Jiang, J., Kuang, S., Tang, L., Tang, W., Zhang, Y., et al. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.12.060 · Cited by 61

The role of tetrahydrobiopterin in inflammation and cardiovascular disease

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Low-Fat Diet and Exercise Preserve eNOS Regulation and Endothelial Function in the Penis of Early Atherosclerotic Pigs: A Molecular Analysis

Musicki, B., Liu, T., Strong, T., Jin, L., Laughlin, M. H., Turk, J. R., & Burnett, A. L. (2008) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2007.00731.x · Cited by 58

Regulation of Vascular Function and Inflammation via Cross Talk of Reactive Oxygen and Nitrogen Species from Mitochondria or NADPH Oxidase—Implications for Diabetes Progression

Daiber, A., Steven, S., Vujačić-Mirski, K., Kalinovic, S., Oelze, M. W., Lisa, F. D., & Münzel, T. F. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21103405 · Cited by 59

Plasma Tetrahydrobiopterin/Dihydrobiopterin Ratio A Possible Marker of Endothelial Dysfunction

Takeda, M., Yamashita, T., Shinohara, M., Sasaki, N., Takaya, T., Nakajima, K., Inoue, N., Masano, T., Tawa, H., Satomi‐Kobayashi, S., et al. (2009) · Circulation Journal · doi:10.1253/circj.cj-08-0850 · Cited by 58

Functional alterations in endothelial NO, PGI2 and EDHF pathways in aorta in ApoE/LDLR−/− mice

Csányi, G., Gajda, M., Franczyk‐Żarów, M., Kostogrys, R. B., Gwóźdź, P., Mateuszuk, Ł., Sternak, M., Wójcik, L., Zalewska, T., Walski, M., et al. (2012) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2012.02.002 · Cited by 54

Metallothionein Abrogates GTP Cyclohydrolase I Inhibition–Induced Cardiac Contractile and Morphological Defects

Ceylan‐Isik, A. F., Guo, K. K., Carlson, E. C., Privratsky, J. R., Liao, S.-J., Cai, L. F., Chen, A. F., & Ren, J. T. (2009) · Hypertension · doi:10.1161/hypertensionaha.108.123422 · Cited by 55

Augmentation of Vascular Remodeling by Uncoupled Endothelial Nitric Oxide Synthase in a Mouse Model of Diabetes Mellitus

Sasaki, N., Yamashita, T., Takaya, T., Shinohara, M., Shiraki, R., Takeda, M., Emoto, N., Fukatsu, A., Hayashi, T., Ikemoto, K., et al. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.160754 · Cited by 56

A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance

Bailey, J. D., Shaw, A., Fischer, R., Ryan, B. J., Kessler, B. M., McCullagh, J., Wade‐Martins, R., Channon, K. M., & Crabtree, M. J. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.01.012 · Cited by 53

Nitric oxide, angiotensin II, and reactive oxygen species in hypertension and atherogenesis

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Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism

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Antioxidants and endothelial nitric oxide synthesis

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Nitric Oxide is a Central Common Metabolite in Vascular Dysfunction Associated with Diseases of Human Pregnancy

Leiva, A., Fuenzalida, B., Barros, E., Sobrevia, B., Salsoso, R., Sáez, T., Villalobos-Labra, R., Silva, L., Chiarello, D. I., Toledo, F., et al. (2016) · Current Vascular Pharmacology · doi:10.2174/1570161114666160222115158 · Cited by 50

Tetrahydrobiopterin in energy metabolism and metabolic diseases

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Fenofibrate plus Metformin Produces Cardioprotection in a Type 2 Diabetes and Acute Myocardial Infarction Model

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Effects of resveratrol on eNOS in the endothelium and the perivascular adipose tissue

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Modeling of biopterin-dependent pathways of eNOS for nitric oxide and superoxide production

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Regulation of Endothelial Cell Tetrahydrobiopterin

Harrison, D. G., Chen, W., Dikalov, S., & Li, L. (2010) · Advances in pharmacology · doi:10.1016/b978-0-12-385061-4.00005-2 · Cited by 41

Oral Tetrahydrobiopterin Treatment Prevents Accelerated Atherosclerosis Caused by Oscillatory Shear Stress

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Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression

Douglas, G., Hale, A., Patel, J., Chuaiphichai, S., Zen, A. A. H., Rashbrook, V. S., Trelfa, L., Crabtree, M. J., McNeill, E., & Channon, K. M. (2018) · Cardiovascular Research · doi:10.1093/cvr/cvy078 · Cited by 49

A key role for tetrahydrobiopterin‐dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin‐deficient mice

Chuaiphichai, S., Crabtree, M. J., McNeill, E., Hale, A., Trelfa, L., Channon, K. M., & Douglas, G. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13728 · Cited by 52

The requirement for endothelial cell tetrahydrobiopterin in health and disease

Chuaiphichai, S. (2014) · Oxford University Research Archive (ORA) (University of Oxford) · doi:10.5287/ora-qzkjnpkkb

Increased vascular biosynthesis of tetrahydrobiopterin in apolipoprotein E-deficient mice

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