Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A “Set Up” for Vascular Disease

Hemodynamic Patterns of Age-Related Changes in Blood Pressure: The Framingham Heart Study

Franklin, S. S., Gustin, W., Wong, N. D., Larson, M. G., Weber, M. A., Kannel, W. B., & Levy, D. (1997) · Circulation · doi:10.1161/01.cir.96.1.308 · Cited by 2,321

Impact of Aortic Stiffness on Survival in End-Stage Renal Disease

Blacher, J., Guerin, A. P., Pannier, B., Marchais, S. J., Safar, M. E., & London, G. M. (1999) · Circulation · doi:10.1161/01.cir.99.18.2434 · Cited by 2,138

Is Pulse Pressure Useful in Predicting Risk for Coronary Heart Disease?

Franklin, S. S., Khan, S. A., Wong, N. D., Larson, M. G., & Levy, D. A. (1999) · Circulation · doi:10.1161/01.cir.100.4.354 · Cited by 1,756

Aortic Stiffness Is an Independent Predictor of Primary Coronary Events in Hypertensive Patients

Boutouyrie, P., Tropeano, A., Asmar, R. G., Gautier, I., Bénétos, A., Lacolley, P. J., & Laurent, S. (2002) · Hypertension · doi:10.1161/hy0102.099031 · Cited by 1,745

Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients

Blacher, J., Asmar, R., Djane, S., London, G. M., & Safar, M. E. (1999) · Hypertension · doi:10.1161/01.hyp.33.5.1111 · Cited by 1,493

Does the Relation of Blood Pressure to Coronary Heart Disease Risk Change With Aging?: The Framingham Heart Study

Franklin, S. S., Larson, M. G., Khan, S. A., Wong, N. D., Leip, E. P., Kannel, W. B., & Levy, D. (2001) · Circulation · doi:10.1161/01.cir.103.9.1245 · Cited by 1,390

Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women

Celermajer, D. S., Sørensen, K. E., Spiegelhalter, D. J., Georgakopoulos, D., Robinson, J. T. C., & Deanfield, J. E. (1994) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)90305-0 · Cited by 1,354

Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises

Lakatta, E. G., & Levy, D. A. (2003) · Circulation · doi:10.1161/01.cir.0000048893.62841.f7 · Cited by 1,257

Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises

Lakatta, E. G. (2003) · Circulation · doi:10.1161/01.cir.0000048894.99865.02 · Cited by 1,105

Effects of age and aerobic capacity on arterial stiffness in healthy adults.

Vaitkevicius, P. V., Fleg, J. L., Engel, J.-H., O’Connor, F. C., Wright, J. G., Lakatta, L. E., Yin, F. C. P., & Lakatta, E. G. (1993) · Circulation · doi:10.1161/01.cir.88.4.1456 · Cited by 1,085

Mortality and safety of catheter ablation for antiarrhythmic drug-refractory ventricular tachycardia in elderly patients with coronary artery disease

Inada, K., Roberts‐Thomson, K. C., Seiler, J., Steven, D., Tedrow, U. B., Koplan, B. A., & Stevenson, W. G. (2010) · Heart Rhythm · doi:10.1016/j.hrthm.2010.02.019 · Cited by 41

Nitric oxide regulates tissue transglutaminase localization and function in the vasculature

Jandu, S. K., Webb, A. K., Pak, A., Sevinc, B., Nyhan, D. P., Belkin, A. M., Flavahan, N. A., Berkowitz, D. E., & Santhanam, L. (2011) · Amino Acids · doi:10.1007/s00726-011-1090-0 · Cited by 40

Aging and arterial-cardiac interactions in the elderly

Maruyama, Y. (2011) · International Journal of Cardiology · doi:10.1016/j.ijcard.2011.01.087 · Cited by 40

Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies

Zhang, L., Connelly, J. J., Peppel, K., Brian, L., Shah, S. H., Nelson, S. C., Crosslin, D. R., Wang, T., Allen, A. S., Kraus, W. E., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq172 · Cited by 40

Heart Failure as an Aging-Related Phenotype

Morita, H., & Komuro, I. (2018) · International Heart Journal · doi:10.1536/ihj.17-519 · Cited by 40

Quercetin-induced apoptosis ameliorates vascular smooth muscle cell senescence through AMP-activated protein kinase signaling pathway

Kim, S. G., Sung, J. Y., Kim, J., & Choi, H. C. (2020) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2020.24.1.69 · Cited by 42

Tumor Necrosis Factor Alpha-Mediated Inflammation and Remodeling of the Extracellular Matrix Underlies Aortic Stiffening Induced by the Common Chemotherapeutic Agent Doxorubicin

Clayton, Z. S., Brunt, V. E., Hutton, D. A., Casso, A. G., Ziemba, B. P., Melov, S., Campisi, J., & Seals, D. R. (2021) · Hypertension · doi:10.1161/hypertensionaha.120.16759 · Cited by 40

Ageing, Age-Related Cardiovascular Risk and the Beneficial Role of Natural Components Intake

Rysz, J., Franczyk, B., Rysz-Górzyńska, M., & Gluba-Brzózka, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010183 · Cited by 41

Matrix Metalloproteinases and Descending Aortic Aneurysms: Parity, Disparity, and Switch

Theruvath, T. P., Jones, J. A., & Ikonomidis, J. S. (2011) · Journal of Cardiac Surgery · doi:10.1111/j.1540-8191.2011.01315.x · Cited by 40

Hydrogen sulfide delays nicotinamide-induced premature senescence via upregulation of SIRT1 in human umbilical vein endothelial cells

Zheng, M., Qiao, W., Cui, J., Liu, L., Liu, H., Wang, Z., & Yan, C. (2014) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-014-2046-y · Cited by 40

Physiological Changes in Human Cardiac Sympathetic Innervation and Activity Assessed by 123I-Metaiodobenzylguanidine (MIBG) Imaging

Sakata, K., Iida, K., Mochizuki, N., Ito, M., & Nakaya, Y. (2009) · Circulation Journal · doi:10.1253/circj.cj-08-0614 · Cited by 40

Role of telomeres in vascular senescence

Minamino, T. (2007) · Frontiers in bioscience · doi:10.2741/2902 · Cited by 39

Age-independent association of pulse pressure with cerebral white matter lesions in asymptomatic elderly individuals

Kim, C. K., Lee, S., Kim, B. J., Ryu, W., & Yoon, B. (2010) · Journal of Hypertension · doi:10.1097/hjh.0b013e3283408ffb · Cited by 40

Aging enhances contraction to thromboxane A2 in aorta from female senescence-accelerated mice

Novella, S., Dantas, A. P., Segarra, G., Novensà, L., Heras, M., Hermenegildo, C., & Medina, P. (2011) · AGE · doi:10.1007/s11357-011-9337-y · Cited by 41

Blood Pressure in Relation to Age and Frailty

Rockwood, M. R. H., & Howlett, S. E. (2011) · Canadian Geriatrics Journal · doi:10.5770/cgj.v14i1.1 · Cited by 40

Cardiovascular adaptations to exercise training in postmenopausal women with type 2 diabetes mellitus

McGavock, J., Mandic, S., Lewanczuk, R. Z., Koller, M., Muhll, I. V., Quinney, A., Taylor, D. A., Welsh, R. C., & Haykowsky, M. J. (2004) · Cardiovascular Diabetology · doi:10.1186/1475-2840-3-3 · Cited by 40

Association of biological age acceleration with cardiac morphology, function, and incident heart failure: insights from UK Biobank participants

Mao, R., Wang, F., Zhong, Y., Xin, M., Zhang, T., & Li, J. (2024) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeae126 · Cited by 40

Aging-associated insulin resistance predisposes to hypertension and its reversal by exercise: the role of vascular vasorelaxation to insulin

Li, Q., Zheng-ying, X., Bai-ping, H., Tian, Z., Zhang, H., Gou, W.-Y., Wang, H., Gao, F., & Zhang, Q. (2008) · Basic Research in Cardiology · doi:10.1007/s00395-008-0754-8 · Cited by 39

The cross-sectional association of sitting time with carotid artery stiffness in young adults

Huynh, Q. L., Blizzard, C. L., Sharman, J. E., Magnussen, C. G., Dwyer, T., & Venn, A. (2014) · BMJ Open · doi:10.1136/bmjopen-2013-004384 · Cited by 40

Lifelong Cyclic Mechanical Strain Promotes Large Elastic Artery Stiffening: Increased Pulse Pressure and Old Age-Related Organ Failure

Thorin‐Trescases, N., & Thorin, É. (2015) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2015.12.022 · Cited by 39

Chronic Endurance Exercise Impairs Cardiac Structure and Function in Middle-Aged Mice with Impaired Nrf2 Signaling

Shanmugam, G., Narasimhan, M., Conley, R. L., Sairam, T., Kumar, A., Mason, R. P., Ramalingam, S., Hoidal, J. R., & Rajasekaran, N. S. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00268 · Cited by 39

Prospective observational study in elderly patients with non-valvular atrial fibrillation: Rationale and design of the All Nippon AF In the Elderly (ANAFIE) Registry

Inoue, H., Yamashita, T., Akao, M., Atarashi, H., Ikeda, T., Okumura, K., Koretsune, Y., Shimizu, W., Tsutsui, H., Toyoda, Ḱ., et al. (2018) · Journal of Cardiology · doi:10.1016/j.jjcc.2018.02.018 · Cited by 39

Effects of Resistance Training on Arterial Stiffness in Persons at Risk for Cardiovascular Disease: A Meta-analysis

Evans, W., Willey, Q., Hanson, E. D., & Stoner, L. R. (2018) · Sports Medicine · doi:10.1007/s40279-018-1001-6 · Cited by 39

Prevalence of type III arch configuration in patients with type B aortic dissection

Marrocco-Trischitta, M. M., Rylski, B., Schofer, F., Secchi, F., Piffaretti, G., de Beaufort, H., Belvroy, V. M., Bismuth, J. X., Czerny, M., & Trimarchi, S. (2019) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezz137 · Cited by 39

Long‐term repopulation of aged bone marrow stem cells using young Sca‐1 cells promotes aged heart rejuvenation

Li, J., Li, S., Dong, J., Alibhai, F. J., Zhang, C., Shao, Z., Song, H., he, S. T., Yin, W., Wu, J., et al. (2019) · Aging Cell · doi:10.1111/acel.13026 · Cited by 39

Glucocorticoid Signaling and the Aging Heart

Cruz‐Topete, D., Oakley, R. H., & Cidlowski, J. A. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00347 · Cited by 44

Vascular Ageing in Youth: A Call to Action

Climie, R. E., Park, C. M., Avolio, A. P., Mynard, J. P., Kruger, R., & Bruno, R. M. (2021) · Heart Lung and Circulation · doi:10.1016/j.hlc.2021.06.516 · Cited by 39

Increased Monocytic Adhesion by Senescence in Human Umbilical Vein Endothelial Cells

Yanaka, M., Honma, T., Sato, K., Shinohara, N., Ito, J., Tanaka, Y., Tsuduki, T., & Ikeda, I. (2011) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.100909 · Cited by 39

Determinants of Aortic Root Dilatation and Reference Values Among Young Adults Over a 20-Year Period

Teixidó‐Turà, G., de Almeida, A. L. C., Choi, E., Gjesdal, O., Jacobs, D. R., Dietz, H. C., Liu, K., Sidney, S. S., Lewis, C. E., David Garcia-dorado, A., et al. (2015) · Hypertension · doi:10.1161/hypertensionaha.115.05156 · Cited by 39

Habitual aerobic exercise is associated with smaller femoral artery intima–media thickness with age in healthy men and women

Moreau, K. L., Silver, A., Dinenno, F. A., & Seals, D. R. (2006) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/01.hjr.0000230103.55653.42 · Cited by 39

Aging hearts and vessels: Masters of adaptation and survival

Pepe, S., & Lakatta, E. G. (2005) · Cardiovascular Research · doi:10.1016/j.cardiores.2005.03.004 · Cited by 39

Age-related vascular gene expression profiling in mice

Rammos, C., Hendgen-Cotta, U. B., Deenen, R., Pohl, J., Stock, P., Hinzmann, C., Kelm, M., & Rassaf, T. (2014) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2014.01.001 · Cited by 35

Spectral and symbolic analysis of the effect of gender and postural change on cardiac autonomic modulation in healthy elderly subjects

Perseguini, N. M., Takahashi, A. C. D. M., Rebelatto, J. R., Silva, E. D. C., Borghi‐Silva, A., Porta, A., Montano, N., & Catai, A. M. (2010) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2010007500137 · Cited by 38

Effect of exercise training on biologic vascular age in healthy seniors

Shibata, S., & Levine, B. D. (2012) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00511.2011 · Cited by 38

Cardiac Micro–Computed Tomography Imaging of the Aging Coronary Vasculature

Sangaralingham, S. J., Ritman, E. L., McKie, P. M., Ichiki, T., Lerman, A., Scott, C. G., Martín, F. L., Harders, G. E., Bellavia, D., & Burnett, J. C. J. (2012) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.112.973057 · Cited by 38

The effects of resistance exercise training on arterial stiffness in metabolic syndrome

DeVallance, E., Fournier, S., Lemaster, K., Moore, C. W., Asano, S., Bonner, D., Donley, D., Olfert, I. M., & Chantler, P. D. (2016) · European Journal of Applied Physiology · doi:10.1007/s00421-016-3348-4 · Cited by 39

Socioeconomic status, education, and aortic stiffness progression over 5 years

Trudel, X., Shipley, M. J., McEniery, C. M., Wilkinson, I. B., & Brunner, E. J. (2016) · Journal of Hypertension · doi:10.1097/hjh.0000000000001057 · Cited by 38

Culprit lesion morphology in young patients with ST-segment elevated myocardial infarction: A clinical, angiographic and optical coherence tomography study

Fang, C., Dai, J., Zhang, S., Wang, Y., Wang, J., Li, L., Wang, Y., Yu, H., Guo, W., Zhang, X., et al. (2019) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2019.08.011 · Cited by 38

Muscle mass reduction, low muscle strength, and their combination are associated with arterial stiffness in community-dwelling elderly population: the Wakayama Study

Zhang, Y., Miyai, N., Abe, K., Utsumi, M., Uematsu, Y., Terada, K., Nakatani, T., Takeshita, T., & Arita, M. (2020) · Journal of Human Hypertension · doi:10.1038/s41371-020-0355-z · Cited by 38

Numerical knockouts–In silico assessment of factors predisposing to thoracic aortic aneurysms

Latorre, M., & Humphrey, J. D. (2020) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1008273 · Cited by 38

Epigenetic dysregulation in cardiovascular aging and disease

Herman, A. B., Occean, J. R., & Sen, P. (2021) · The Journal of Cardiovascular Aging · doi:10.20517/jca.2021.16 · Cited by 39

Effect of combined aerobic and resistance exercise on blood pressure in postmenopausal women: A systematic review and meta-analysis of randomized controlled trials

Xi, H., He, Y., Niu, Y., Sui, X., Zhang, J., Zhu, R., Xu, H., Zhang, S., Li, Y., Yuan, Y., et al. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111560 · Cited by 38

Endothelial SIRT1 as a Target for the Prevention of Arterial Aging: Promises and Challenges

Begum, M. K., Konja, D., Singh, S., Chłopicki, S., & Wang, Y. (2021) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001154 · Cited by 40

Does Arterial Stiffness Predict Atherosclerotic Coronary Events?

McEniery, C. M., & Cockcroft, J. R. (2006) · KARGER eBooks · doi:10.1159/000096728 · Cited by 38

AMPK induces vascular smooth muscle cell senescence via LKB1 dependent pathway

Sung, J. Y., Woo, C.-H., Kang, Y. J., Lee, K. Y., & Choi, H. C. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.08.071 · Cited by 40

Aging-Shifted Prostaglandin Profile in Endothelium as a Factor in Cardiovascular Disorders

Qian, H., Luo, N., & Chi, Y. (2012) · Journal of Aging Research · doi:10.1155/2012/121390 · Cited by 38

Cardiorespiratory Fitness Suppresses Age‐Related Arterial Stiffening in Healthy Adults: A 2‐Year Longitudinal Observational Study

Gando, Y., Murakami, H., Kawakami, R., Yamamoto, K., Kawano, H., Tanaka, N., Sawada, S. S., Miyatake, N., & Miyachi, M. (2015) · Journal of Clinical Hypertension · doi:10.1111/jch.12753 · Cited by 42

Cardiovascular Drug Therapy in Elderly Patients

Mangoni, A. A. (2005) · Drugs & Aging · doi:10.2165/00002512-200522110-00003 · Cited by 38

Anti-ageing interventions for the treatment of cardiovascular disease

Abdellatif, M., Schmid, S., Fuerlinger, A., & Kroemer, G. (2024) · Cardiovascular Research · doi:10.1093/cvr/cvae177 · Cited by 44

Cardiovascular function is better in veteran football players than age‐matched untrained elderly healthy men

Schmidt, J. F., Andersen, T. R., Andersen, L. J., Randers, M. B., Hornstrup, T., Hansen, P. R., Bangsbo, J., & Krustrup, P. (2013) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.12153 · Cited by 37

Variations in the protein level of Omi/HtrA2 in the heart of aged rats may contribute to the increased susceptibility of cardiomyocytes to ischemia/reperfusion injury and cell death

Wang, K., Zhang, J., Liu, J., Tian, J., Wu, Y., Wang, X., Quan, L., Xu, H., Wang, W., & Liu, H. (2012) · AGE · doi:10.1007/s11357-012-9406-x · Cited by 37

Metabolomic profile of arterial stiffness in aged adults

Koh, A. S.-M., Gao, F., Liu, J., Fridianto, K. T., Ching, J., Tan, R., Wong, J.-I., Chua, S. J., Leng, S., Zhong, L., et al. (2017) · Diabetes and Vascular Disease Research · doi:10.1177/1479164117733627 · Cited by 37

Adult Cardiac Stem Cell Aging: A Reversible Stochastic Phenomenon?

Cianflone, E., Torella, M., Chimenti, C., Angelis, A. D., Beltrami, A. P., Urbanek, K., Rota, M., & Torella, D. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/5813147 · Cited by 40

Association between central haemodynamics and risk of all-cause mortality and cardiovascular disease: a systematic review and meta-analysis

Li, W., Huang, Y., & Feng, Y. (2019) · Journal of Human Hypertension · doi:10.1038/s41371-019-0187-x · Cited by 37

Sex Differences in Instantaneous Wave-Free Ratio or Fractional Flow Reserve–Guided Revascularization Strategy

Kim, C. H., Koo, B., Dehbi, H., Lee, J. M., Doh, J., Nam, C., Shin, E., Cook, C., Al-Lamee, R. K., Petraco, R., et al. (2019) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2019.06.035 · Cited by 37

Long Non-coding RNA Aerrie Controls DNA Damage Repair via YBX1 to Maintain Endothelial Cell Function

Pham, T. P., Bink, D. I., Stanicek, L., van Bergen, A. S., van Leeuwen, E., Tran, Y., Matic, L. P., Hedin, U., Wittig, I., Dimmeler, S., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.619079 · Cited by 37

Mechanobiology of Microvascular Function and Structure in Health and Disease: Focus on the Coronary Circulation

Brandt, M. M., Cheng, C., Merkus, D., Duncker, D. J., & Sorop, O. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.771960 · Cited by 40

Sickle cell disease as an accelerated aging syndrome

Idris, I. M., Botchwey, E. A., & Hyacinth, H. I. (2022) · Experimental Biology and Medicine · doi:10.1177/15353702211068522 · Cited by 37

Prevalence of specific variant carotid geometric patterns and incidence of cardiovascular events in older persons

Scuteri, A., Manolio, T. A., Marino, E. K., Arnold, A. M., & Lakatta, E. G. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.08.035 · Cited by 37

Relationship between birthweight and arterial elasticity in childhood

Rondó, P. H. D. C., Lemos, J. O., Pereira, J. A., de Oliveira, J. M., & Innocente, L. R. (2008) · Clinical Science · doi:10.1042/cs20070420 · Cited by 37

Relative contributions of different cardiovascular risk factors to significant arterial stiffness

Song, H., Kim, E. J., Seo, H. S., Kim, S. H., Park, C. G., Han, S. W., & Ryu, K.-H. (2008) · International Journal of Cardiology · doi:10.1016/j.ijcard.2008.10.032 · Cited by 37

Distribution and Correlates of Arterial Compliance Measures in Asymptomatic Young Adults: The Bogalusa Heart Study

Bhuiyan, A. R., LI, S., LI, H., CHEN, W., SRINIVASAN, S., & Berenson, G. S. (2005) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2004.11.039 · Cited by 37

Alternate-day fasting reverses the age-associated hypertrophy phenotype in rat heart by influencing the ERK and PI3K signaling pathways

Castello, L., Maina, M., Testa, G., Cavallini, G., Biasi, F., Donati, A., Leonarduzzi, G., Bergamini, E., Poli, G., & Chiarpotto, E. (2011) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2011.06.006 · Cited by 34

Reduced peripheral arterial blood flow with preserved cardiac output during submaximal bicycle exercise in elderly heart failure

Puntawangkoon, C., Kitzman, D. W., Kritchevsky, S. B., Hamilton, C. A., Nicklas, B. J., Leng, X., Brubaker, P. H., & Hundley, W. G. (2009) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/1532-429x-11-48 · Cited by 37

Gathering of aging and estrogen withdrawal in vascular dysfunction of senescent accelerated mice

Novella, S., Dantas, A. P., Segarra, G., Novensà, L., Bueno, C., Heras, M., Hermenegildo, C., & Medina, P. (2010) · Experimental Gerontology · doi:10.1016/j.exger.2010.07.007 · Cited by 42

Influence of hyperglycemia during and after pregnancy on postpartum vascular function

Davenport, M. H., Goswami, R., Shoemaker, J. K., & Mottola, M. F. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00115.2011 · Cited by 36

Cumulative Community-Level Lead Exposure and Pulse Pressure: The Normative Aging Study

Perlstein, T. S., Weuve, J., Schwartz, J. D., Sparrow, D., Wright, R. O., Litonjua, A. A., Nie, H., & Hu, H. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10350 · Cited by 37

Delay of endothelial cell senescence protects cerebral barrier against age-related dysfunction: role of senolytics and senomorphics

Ya, J., Kadir, R. R. A., & Bayraktutan, U. (2022) · Tissue Barriers · doi:10.1080/21688370.2022.2103353 · Cited by 35

Effect of urolithin A on the improvement of vascular endothelial function depends on the gut microbiota

Nishimoto, Y., Fujisawa, K., Ukawa, Y., Kudoh, M., Funahashi, K., Kishimoto, Y., & Fukuda, S. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1077534 · Cited by 36

Age-related cardiovascular disease and the beneficial effects of calorie restriction

Sung, M. M. Y., & Dyck, J. R. B. (2011) · Heart Failure Reviews · doi:10.1007/s10741-011-9293-8 · Cited by 38

STEMI and heart failure in the elderly: role of adverse remodeling

Jelani, A., & Jugdutt, B. I. (2010) · Heart Failure Reviews · doi:10.1007/s10741-010-9177-3 · Cited by 36

1-Deoxynojirimycin attenuates high glucose-accelerated senescence in human umbilical vein endothelial cells

Shuang, E., Kijima, R., Honma, T., Yamamoto, K., Hatakeyama, Y., Kitano, Y., Kimura, T., Nakagawa, K., Miyazawa, T., & Tsuduki, T. (2014) · Experimental Gerontology · doi:10.1016/j.exger.2014.03.025 · Cited by 36

Do Hypertensive Individuals Have Enlarged Aortic Root Diameters? Insights From Studying the Various Subtypes of Hypertension

Farasat, S. M., Morrell, C., Scuteri, A., Ting, C.-T., Yin, F. C. P., Spurgeon, H. A., Chen, C.-H., Lakatta, E. G., & Najjar, S. S. (2008) · American Journal of Hypertension · doi:10.1038/ajh.2008.10 · Cited by 36

Perioperative management of left ventricular diastolic dysfunction and heart failure: an anesthesiologist's perspective

Ryu, T., & Song, S. Y. (2017) · Korean Journal of Anesthesiology · doi:10.4097/kjae.2017.70.1.3 · Cited by 36

Distinctive molecular signature and activated signaling pathways in aortic smooth muscle cells of patients with myocardial infarction

Wongsurawat, T., Woo, C. C., Giannakakis, A., Lin, X. Y., Cheow, E. S. H., Lee, C. N., Richards, M., Sze, S. K., Nookaew, I., Kuznetsov, V., et al. (2018) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2018.01.024 · Cited by 36

As time flies by: Investigating cardiac aging in the short-lived Drosophila model

Blice‐Baum, A. C., Guida, M. C., Hartley, P. S., Adams, P. D., Bodmer, R., & Cammarato, A. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.11.010 · Cited by 41

Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress

Morgan, R. G., Walker, A. E., Trott, D. W., Machin, D. R., Henson, G. D., Reihl, K. D., Cawthon, R., Denchi, E. L., Liu, Y., Bloom, S. I., et al. (2018) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2018.11.014 · Cited by 39

Phylogenic Determinants of Cardiovascular Frailty, Focus on Hemodynamics and Arterial Smooth Muscle Cells

Michel, J. (2020) · Physiological Reviews · doi:10.1152/physrev.00022.2019 · Cited by 38

Sirtuins, aging, and cardiovascular risks

Favero, G., Franceschetti, L., Rodella, L. F., & Rezzani, R. (2015) · AGE · doi:10.1007/s11357-015-9804-y · Cited by 36

Cardioprotective Actions of Ascorbic Acid during Isoproterenol-Induced Acute Myocardial Infarction in Rats

Buttros, J. B., Bergamaschi, C. T., Ribeiro, D. A., Fracalossi, A. C. C., & Campos, R. R. (2009) · Pharmacology · doi:10.1159/000222245 · Cited by 36

Racial Differences in Arterial Stiffness are Mainly Determined by Blood Pressure Levels: Results From the ELSA‐Brasil Study

Baldo, M. P., Cunha, R. S., Ribeiro, A. L. P., Lotufo, P. A., Chor, D., Barreto, S. M., Benseñor, I. M., Pereira, A. C., & Mill, J. G. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.117.005477 · Cited by 36

Age-dependent associations between blood pressure and coronary artery calcification in asymptomatic adults

Bielak, L. F., Turner, S. T., Franklin, S. S., Sheedy, P. F., & Peyser, P. A. (2004) · Journal of Hypertension · doi:10.1097/00004872-200404000-00014 · Cited by 36

Genomic instability in the naturally and prematurely aged myocardium

De Majo, F., Martens, L., Hegenbarth, J.-C., Rühle, F., Hamczyk, M. R., Nevado, R. M., Andrés, V., Hilbold, E., Bär, C., Thum, T., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2022974118 · Cited by 35

Mitochondrial DNA leakage triggers inflammation in age-related cardiovascular diseases

Ding, W., Chen, J., Zhao, L., Wu, S., Chen, X., & Chen, H. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1287447 · Cited by 41

Endothelial function, arterial stiffness and adherence to the 2010 Dietary Guidelines for Americans: a cross-sectional analysis

Sauder, K. A., Proctor, D. N., Chow, M., Troy, L. M., Wang, N., Vita, J. A., Vasan, R. S., Mitchell, G. F., Jacques, P. F., Hamburg, N. M., et al. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114515000859 · Cited by 35

Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence

Yamagata, K., Suzuki, S., & Tagami, M. (2015) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2015.10.006 · Cited by 35

The role of dipeptidylpeptidase-4 inhibitors in management of cardiovascular disease in diabetes; focus on linagliptin

Aroor, A. R., Manrique‐Acevedo, C., & DeMarco, V. G. (2018) · Cardiovascular Diabetology · doi:10.1186/s12933-018-0704-1 · Cited by 37

P2Y2R activation by ATP induces oxLDL-mediated inflammasome activation through modulation of mitochondrial damage in human endothelial cells

Jin, H., Ko, G. H., Park, S. W., & Kim, H. J. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.04.004 · Cited by 37

Serum from young, sedentary adults who underwent passive heat therapy improves endothelial cell angiogenesis via improved nitric oxide bioavailability

Brunt, V. E., Needham, K. W., Comrada, L. N., Francisco, M. A., Eymann, T. M., & Minson, C. T. (2019) · Temperature · doi:10.1080/23328940.2019.1614851 · Cited by 35

The Impact of Aging on the Association Between Aortic Stiffness and Cerebral Pulsatility Index

Fico, B. G., Miller, K. B., Rivera‐Rivera, L. A., Corkery, A. T., Pearson, A. G., Eisenmann, N. A., Howery, A. J., Rowley, H. A., Johnson, K. M., Johnson, S. C., et al. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.821151 · Cited by 35

Theories and Molecular Basis of Vascular Aging: A Review of the Literature from VascAgeNet Group on Pathophysiological Mechanisms of Vascular Aging

Gkaliagkousi, Ε., Lazaridis, A. A., Doğan, S., Fraenkel, E., Tuna, B. G., Mozos, I. M., VUKIĆEVIĆ, M., Yalçın, Ö., & Gopčević, K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158672 · Cited by 35

Defining Hypotension in Moderate to Severely Injured Trauma Patients: Raising the Bar for the Elderly

Edwards, M., Ley, E. J., Mirocha, J., Hadjibashi, A. A., Margulies, D. R., & Salim, A. (2010) · The American Surgeon · doi:10.1177/000313481007601001 · Cited by 35

Current Status and Characteristics of Hypertension Control in Community Resident Elderly Korean People: Data from a Korean Longitudinal Study on Health and Aging (KLoSHa Study)

Kim, K., Chang, H., Cho, Y., Youn, T., Chung, W., Chae, I., Choi, D., & Kim, C. (2008) · Hypertension Research · doi:10.1291/hypres.31.97 · Cited by 33

Genetics of arterial structure and function: towards new biomarkers for aortic stiffness?

Yasmin, Y., & O’Shaughnessy, K. M. (2008) · Clinical Science · doi:10.1042/cs20070369 · Cited by 35

Pathophysiology of acute coronary syndromes in the elderly

Badimón, L., Bugiardini, R., & Cubedo, J. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.07.205 · Cited by 34

Quantitative assessment of the intracranial vasculature in an older adult population using iCafe

Chen, L., Sun, J., Hippe, D. S., Balu, N., Yuan, Q., Yuan, I., Zhao, X., Li, R., He, L., Hatsukami, T. S., et al. (2019) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2019.02.027 · Cited by 33

Testosterone ameliorates vascular aging via the Gas6/Axl signaling pathway

Chen, Y., Zhou, H., Chen, F., Liu, Y., Han, L., Song, M., Wang, Z., Zhang, W., Shang, Y., & Zhong, M. (2020) · Aging · doi:10.18632/aging.103584 · Cited by 34

Potential Applications of Polyhydroxyalkanoates as a Biomaterial for the Aging Population

Ang, S. L., Sivashankari, R. M., Shaharuddin, B., Chuah, J., Tsuge, T., Abe, H., & Sudesh, K. (2020) · Polymer Degradation and Stability · doi:10.1016/j.polymdegradstab.2020.109371 · Cited by 35

Switching of vascular cells towards atherogenesis, and other factors contributing to atherosclerosis: a systematic review

Shafi, O. (2020) · Thrombosis Journal · doi:10.1186/s12959-020-00240-z · Cited by 36

Cerebrovascular disease in women

Kumar, A., & McCullough, L. D. (2021) · Therapeutic Advances in Neurological Disorders · doi:10.1177/1756286420985237 · Cited by 35

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises. Part III: cellular and molecular clues to heart and arterial aging. Circulation

Lakatta, E. G., Levy, D. A., & Levy, D. A. (2015)

Aging and Cardiovascular Disease

Wissler, R. W., & Robert, L. (1996) · Circulation · doi:10.1161/01.cir.93.9.1608 · Cited by 19

Aging of the Heart and Arteries: A Set-up for Cardiovascular Disease Leading to Heart Failure

Lakatta, E. G. (2006) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2006.08.040

Aging’s Accomplice in Harming the Cardiovascular System

Wei, Y. (2020) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.120.315217

Aging Issues in Cardiology

(2004) · Developments in cardiovascular medicine · doi:10.1007/978-1-4419-8865-2 · Cited by 6