Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A “Set Up” for Vascular Disease

Hemodynamic Patterns of Age-Related Changes in Blood Pressure: The Framingham Heart Study

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Impact of Aortic Stiffness on Survival in End-Stage Renal Disease

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Is Pulse Pressure Useful in Predicting Risk for Coronary Heart Disease?

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Aortic Stiffness Is an Independent Predictor of Primary Coronary Events in Hypertensive Patients

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Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients

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Does the Relation of Blood Pressure to Coronary Heart Disease Risk Change With Aging?: The Framingham Heart Study

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Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women

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Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises

Lakatta, E. G., & Levy, D. A. (2003) · Circulation · doi:10.1161/01.cir.0000048893.62841.f7 · Cited by 1,257

Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises

Lakatta, E. G. (2003) · Circulation · doi:10.1161/01.cir.0000048894.99865.02 · Cited by 1,105

Effects of age and aerobic capacity on arterial stiffness in healthy adults.

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Expert consensus document on arterial stiffness: methodological issues and clinical applications

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Exercise and Physical Activity for Older Adults

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Use of Carotid Ultrasound to Identify Subclinical Vascular Disease and Evaluate Cardiovascular Disease Risk: A Consensus Statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force Endorsed by the Society for Vascular Medicine

Stein, J. H., Korcarz, C. E., Hurst, R. T., Lonn, E., Kendall, C. B., Mohler, E. R., Najjar, S. S., Rembold, C. M., & Post, W. S. (2008) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2007.11.011 · Cited by 2,454

Exercise Standards for Testing and Training: A Scientific Statement From the American Heart Association

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Myocardial Fatty Acid Metabolism in Health and Disease

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Mechanisms, Pathophysiology, and Therapy of Arterial Stiffness

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The intersection between aging and cardiovascular disease

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Changes in Arterial Stiffness and Wave Reflection With Advancing Age in Healthy Men and Women

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Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness

Townsend, R. R., Wilkinson, I. B., Schiffrin, E. L., Avolio, A. P., Chirinos, J. A., Cockcroft, J. R., Heffernan, K. S., Lakatta, E. G., McEniery, C. M., Mitchell, G. F., et al. (2015) · Hypertension · doi:10.1161/hyp.0000000000000033 · Cited by 1,527

Normal Vascular Aging: Differential Effects on Wave Reflection and Aortic Pulse Wave Velocity

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Phenomics: the next challenge

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Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises

Lakatta, E. G., & Levy, D. A. (2003) · Circulation · doi:10.1161/01.cir.0000048893.62841.f7 · Cited by 1,257

Mechanical Factors in Arterial Aging

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Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

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Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises

Lakatta, E. G. (2003) · Circulation · doi:10.1161/01.cir.0000048894.99865.02 · Cited by 1,105

Toward ubiquitous blood pressure monitoring via pulse transit time: Theory and practice

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Mechanisms of Vascular Aging

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Age- and Gender-Related Ventricular-Vascular Stiffening

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Mitochondrial Dysfunction in Atherosclerosis

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Aging Biology and Geriatric Clinical Pharmacology

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Caloric restriction

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Physical activity and exercise: Strategies to manage frailty

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Aging-Associated Cardiovascular Changes and Their Relationship to Heart Failure

Strait, J. B., & Lakatta, E. G. (2011) · Heart Failure Clinics · doi:10.1016/j.hfc.2011.08.011 · Cited by 769

Aging and vascular endothelial function in humans

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Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation

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Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease

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Mechanisms of Dysfunction in the Aging Vasculature and Role in Age-Related Disease

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Progression of Left Ventricular Diastolic Dysfunction and Risk of Heart Failure

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Monocyte-macrophages and T cells in atherosclerosis

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Arterial Aging: Is It an Immutable Cardiovascular Risk Factor?

Najjar, S. S., Scuteri, A., & Lakatta, E. G. (2005) · Hypertension · doi:10.1161/01.hyp.0000177474.06749.98 · Cited by 640

Aging and Arterial Stiffness

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The Aging Cardiovascular System

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Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

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Oxidative stress and vascular inflammation in aging

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Vascular Cell Senescence: Contribution to Atherosclerosis

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Aortic Diameter, Aortic Stiffness, and Wave Reflection Increase With Age and Isolated Systolic Hypertension

O’Rourke, M. F., & Nichols, W. W. (2005) · Hypertension · doi:10.1161/01.hyp.0000153793.84859.b8 · Cited by 543

Effect of Aging and Physical Activity on Left Ventricular Compliance

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Cellular and molecular biology of aging endothelial cells

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Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging

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When drug therapy gets old: pharmacokinetics and pharmacodynamics in the elderly

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Chronic Oxidative Stress Compromises Telomere Integrity and Accelerates the Onset of Senescence in Human Endothelial Cells

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2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope

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Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults

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Cardiac Stem Cells and Mechanisms of Myocardial Regeneration

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Aging and Autophagy in the Heart

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Inflammation and endothelial dysfunction during aging: role of NF-κB

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2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society

Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000499 · Cited by 463

Exercise Attenuates the Major Hallmarks of Aging

Garatachea, N., Pareja-Galeano, H., Sanchis-Gomar, F., Santos-Lozano, A., Fiuza-Luces, C., Morán, M., Emanuele, E., Joyner, M. J., & Lucia, A. (2015) · Rejuvenation Research · doi:10.1089/rej.2014.1623 · Cited by 413

2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society

Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000498 · Cited by 411

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

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Vascular endothelial senescence: from mechanisms to pathophysiology

Erusalimsky, J. D. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.91353.2008 · Cited by 399

Senescence and Death of Primitive Cells and Myocytes Lead to Premature Cardiac Aging and Heart Failure

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Reduced Ascending Aortic Strain and Distensibility

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Vascular Fibrosis in Aging and Hypertension: Molecular Mechanisms and Clinical Implications

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Age-Related Left Ventricular Remodeling and Associated Risk for Cardiovascular Outcomes

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Invited Review: Aging and the cardiovascular system

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Habitual exercise and arterial aging

Seals, D. R., DeSouza, C. A., Donato, A. J., & Tanaka, H. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90553.2008 · Cited by 379

Atorvastatin enhances the therapeutic efficacy of mesenchymal stem cells-derived exosomes in acute myocardial infarction via up-regulating long non-coding RNA H19

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The roles of senescence and telomere shortening in cardiovascular disease

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Extracellular matrix remodeling and matrix metalloproteinases in the vascular wall during aging and in pathological conditions

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Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway

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25-Hydroxyvitamin D Deficiency Is Associated With Inflammation-Linked Vascular Endothelial Dysfunction in Middle-Aged and Older Adults

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L-Arginine Therapy in Acute Myocardial Infarction: The Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) Randomized Clinical Trial

Schulman, S. P., Becker, L. C., Kass, D. A., Champion, H. C., Terrin, M. L., Forman, S., Ernst, K. V., Kelemen, M. D., Townsend, S. N., Capriotti, A., et al. (2006) · JAMA · doi:10.1001/jama.295.1.58 · Cited by 357

Endothelial Function Is Impaired across the Stages of the Menopause Transition in Healthy Women

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Premature aging‐like phenotype in fibroblast growth factor 23 null mice is a vitamin D‐mediated process

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Effect of acute and chronic ascorbic acid on flow‐mediated dilatation with sedentary and physically active human ageing

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Vascular biology of ageing—Implications in hypertension

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Exercise modulates oxidative stress and inflammation in aging and cardiovascular diseases

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Cardiac Aging: From Molecular Mechanisms to Significance in Human Health and Disease

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Age-related Impairment of Vascular Structure and Functions

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Mechanisms of Vascular Aging, A Geroscience Perspective

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2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope

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Extension of Human Cell Lifespan by Nicotinamide Phosphoribosyltransferase

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Association Between Advanced Age and Vascular Disease in Different Arterial Territories

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Endothelial dysfunction and aging: An update

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Age-associated changes in cardiovascular structure and function: a fertile milieu for future disease

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Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity

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Angiotensin II Induces Premature Senescence of Vascular Smooth Muscle Cells and Accelerates the Development of Atherosclerosis via a p21-Dependent Pathway

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Age-Related Changes in Aortic Arch Geometry

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