Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A “Set Up” for Vascular Disease

Hemodynamic Patterns of Age-Related Changes in Blood Pressure: The Framingham Heart Study

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Impact of Aortic Stiffness on Survival in End-Stage Renal Disease

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Is Pulse Pressure Useful in Predicting Risk for Coronary Heart Disease?

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Aortic Stiffness Is an Independent Predictor of Primary Coronary Events in Hypertensive Patients

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Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients

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Does the Relation of Blood Pressure to Coronary Heart Disease Risk Change With Aging?: The Framingham Heart Study

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Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women

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Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises

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Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises

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Effects of age and aerobic capacity on arterial stiffness in healthy adults.

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Biological aortic age derived from the arterial pressure waveform

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Age-related remodeling of small arteries is accompanied by increased sphingomyelinase activity and accumulation of long-chain ceramides

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The Effect of Physical Activity on Passive Leg Movement–Induced Vasodilation with Age

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Visibility graph analysis of very short-term heart rate variability during sleep

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Sex Differences in Peripheral Vascular Disease: A Scientific Statement From the American Heart Association

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Brachial-ankle pulse wave velocity is associated with coronary calcium in young and middle-aged asymptomatic adults: The Kangbuk Samsung Health Study

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Pulse wave velocity and flow in the carotid artery versus the aortic arch: Effects of aging

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Use of Metformin in Diseases of Aging

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Enzymatic and free radical formation of cis- and trans- epoxyeicosatrienoic acids in vitro and in vivo

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Hesperidin reverses perivascular adipose-mediated aortic stiffness with aging

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Relaxin reverses maladaptive remodeling of the aged heart through Wnt-signaling

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Integrating affective and cognitive correlates of heart rate variability: A structural equation modeling approach

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Femoral Plaques Confound the Association of Circulating Oxidized Low-Density Lipoprotein With Carotid Atherosclerosis in a General Population Aged 35 to 55 Years

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Induction of bovine articular chondrocyte senescence with oxidized low‐density lipoprotein through lectin‐like oxidized low‐density lipoprotein receptor 1

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Crataegus special extract WS®1442 prevents aging-related endothelial dysfunction

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Resveratrol Decreases TXNIP mRNA and Protein Nuclear Expressions With an Arterial Function Improvement in Old Mice

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Lack of independent relationship between age-related kidney function decline and carotid intima-media thickness in a healthy Chinese population

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Effect of omega-3 polyunsaturated fatty acid supplementation on central arterial stiffness and arterial wave reflections in young and older healthy adults

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Age-related arterial immune cell infiltration in mice is attenuated by caloric restriction or voluntary exercise

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Deferiprone inhibits iron overload-induced tissue factor bearing endothelial microparticle generation by inhibition oxidative stress induced mitochondrial injury, and apoptosis

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Are Age-Associated Diseases an Integral Part of Aging?

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Genome-wide transcript and protein analysis highlights the role of protein homeostasis in the aging mouse heartPreprint

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Impact of air pollution on cardiovascular aging

Kuntić, M., Kuntić, I., Hahad, O., Lelieveld, J., Münzel, T. F., & Daiber, A. (2023) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2023.111857 · Cited by 36

Cardiovascular Aging and Exercise: Implications for Heart Failure Prevention and Management

Subramanian, V., Tucker, W. J., Peters, A. E., Upadhya, B., Kitzman, D. W., & Pandey, A. (2025) · Circulation Research · doi:10.1161/circresaha.125.325531 · Cited by 34

Rb1 Protects Endothelial Cells from Hydrogen Peroxide-Induced Cell Senescence by Modulating Redox Status

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Ageing-exaggerated proliferation of vascular smooth muscle cells is related to attenuation of Jagged1 expression in endothelial cells

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Aging alters reactivity of microvascular resistance networks in mouse gluteus maximus muscle

Sinkler, S. Y., & Segal, S. S. (2014) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00368.2014 · Cited by 32

Modulation of Circulating Macrophage Migration Inhibitory Factor in the Elderly

Rammos, C., Hendgen-Cotta, U. B., Pohl, J., Totzeck, M., Luedike, P., Schulze, V. T., Kelm, M., & Rassaf, T. (2014) · BioMed Research International · doi:10.1155/2014/582586 · Cited by 31

Testosterone delays vascular smooth muscle cell senescence and inhibits collagen synthesis via the Gas6/Axl signaling pathway

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Extra- and intracranial blood flow regulation during the cold pressor test: influence of age

Flück, D., Ainslie, P. N., Bain, A. R., Wildfong, K. W., Morris, L. E., & Fisher, J. P. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00224.2017 · Cited by 32

Novel role of PKR in palmitate-induced Sirt1 inactivation and endothelial cell senescence

Li, Y., Peng, Z., Wang, C., Li, L., Leng, Y., Chen, R., Yuan, H., Zhou, S., Zhang, Z., & Chen, A. F. (2018) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00038.2018 · Cited by 32

Hemodynamic Characterization of Primary Hypertension in Children and Adolescents

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Vascular Aging and Central Aortic Blood Pressure: From Pathophysiology to Treatment

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NLRP3 inflammasome links vascular senescence to diabetic vascular lesions

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Cardiovascular protection afforded by caloric restriction: Essential role of nitric oxide synthase

Shinmura, K. (2011) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/j.1447-0594.2010.00675.x · Cited by 31

Cardiac Aging and Insulin Resistance: Could Insulin/Insulin-Like Growth Factor (IGF) Signaling be used as a Therapeutic Target?

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Effects of Old Age on Vascular Complexity and Dispersion of the Hepatic Sinusoidal Network

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Retarding the senescence of human vascular endothelial cells induced by hydrogen peroxide: effects of 17beta-estradiol (E2) mediated mitochondria protection

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Depressed perivascular sensory innervation of mouse mesenteric arteries with advanced age

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Matrice extracellulaire et vieillissement vasculaire

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Explainable AI Associates ECG Aging Effects with Increased Cardiovascular Risk in a Longitudinal Population Study

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Impact of dietary nitrate on age-related diastolic dysfunction

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Age and sex differences in muscle sympathetic nerve activity in relation to haemodynamics, blood volume and left ventricular size

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Perfusion pressure and movement-induced hyperemia: evidence of limited vascular function and vasodilatory reserve with age

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The Soluble VEGF Receptor sFlt-1 Contributes to Impaired Neovascularization in Aged Mice

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Morning Diastolic Blood Pressure May Be Independently Associated With Severity of Obstructive Sleep Apnea in Non-Hypertensive Patients: A Cross-Sectional Study

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Antiplatelet therapy in very elderly and comorbid patients with acute coronary syndromes.

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Pregnancy as a model for aging

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Effects of multicomponent exercise training intervention on hemodynamic and physical function in older residents of long-term care facilities: A multicenter randomized clinical controlled trial

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Vascular Ageing Features Caused by Selective DNA Damage in Smooth Muscle Cell

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Mechanisms underlying the effects of caloric restriction on hypertension

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Initiation of 3,3‐dimethyl‐1‐butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in mice

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Restoration of Erectile Capacity in Normotensive Aged Rats by Modulation of Angiotensin Receptor Type 1

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Vascular oxidative stress and inflammation increase with age: ameliorating effects of α‐lipoic acid supplementation

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Impaired cross-activation of β3 integrin and VEGFR-2 on endothelial progenitor cells with aging decreases angiogenesis in response to hypoxia

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Red wine extract protects against oxidative-stress-induced endothelial senescence

Botden, I. P. G., Oeseburg, H., Durik, M., Leijten, F. P. J., der Zee, L. C. V. V., Musterd‐Bhaggoe, U. M., Garrelds, I. M., Seynhaeve, A. L. B., Langendonk, J. G., Sijbrands, E. J. G., et al. (2012) · Clinical Science · doi:10.1042/cs20110679 · Cited by 34

CD69 Plays a Beneficial Role in Ischemic Stroke by Dampening Endothelial Activation

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Severe impairment of ventricular compliance accounts for advanced age-associated hemodynamic dysfunction in rats

Rozenberg, S., Tavernier, B., Riou, B., Bernard Swynghedauw, A., Page, C. L., Boucher, F. R., de Leiris, J., & BESSE, S. (2006) · Experimental Gerontology · doi:10.1016/j.exger.2005.11.009 · Cited by 31

Protein expression dynamics during replicative senescence of endothelial cells studied by 2‐D difference in‐gel electrophoresis

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Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence

Barros, P. R., Costa, T. J. D., Akamine, E. H., & Tostes, R. C. (2021) · Frontiers in Aging · doi:10.3389/fragi.2021.727604 · Cited by 33

Unraveling the Intricate Roles of Exosomes in Cardiovascular Diseases: A Comprehensive Review of Physiological Significance and Pathological Implications

Zhang, S., Yang, Y., Lv, X., Liu, W.-D., Zhu, S., Wang, Y., & Xu, H.-F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242115677 · Cited by 24

Targeting the hallmarks of aging: mechanisms and therapeutic opportunities

Sanada, F., Hayashi, S., & Morishita, R. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1631578 · Cited by 40

Impact of global hemodynamic load on exercise capacity in aortic stenosis

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Age‐associated downregulation of vasohibin‐1 in vascular endothelial cells

Takeda, E., Suzuki, Y., & Sato, Y. (2016) · Aging Cell · doi:10.1111/acel.12497 · Cited by 30

Impact of tapering of arterial vessels on blood pressure, pulse wave velocity, and wave intensity analysis using one‐dimensional computational model

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Relationship of Exercise Capacity and Left Ventricular Dimensions in Patients with a Normal Ejection Fraction. An Exploratory Study

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Aortic root dilatation in hypertensive patients: A multicenter survey in echocardiographic practice

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Cardiopulmonary aspects of anaesthesia for the elderly

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Cardiac aging

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Early atherogenesis in senescence-accelerated mice

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The procyanidin-induced pseudo laminar shear stress response: a new concept for the reversal of endothelial dysfunction

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Results of Blood Inflammatory Markers Are Associated More Strongly With Toe-Brachial Index Than With Ankle-Brachial Index in Patients With Type 2 Diabetes

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Photobiomodulation therapy mitigates cardiovascular aging and improves survival

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Endogenous sulfur dioxide deficiency as a driver of cardiomyocyte senescence through abolishing sulphenylation of STAT3 at cysteine 259

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Research on the Age-Related Changes in the Nitric Oxide Pathway in the Arteries of Rats and the Intervention Effect of Dehydroepiandrosterone

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Heart Failure in Very Old Adults

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The impact of the metabolic syndrome – but not of hypertension – on all-cause mortality disappears in the elderly

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