Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A “Set Up” for Vascular Disease

Hemodynamic Patterns of Age-Related Changes in Blood Pressure: The Framingham Heart Study

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Impact of Aortic Stiffness on Survival in End-Stage Renal Disease

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Is Pulse Pressure Useful in Predicting Risk for Coronary Heart Disease?

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Aortic Stiffness Is an Independent Predictor of Primary Coronary Events in Hypertensive Patients

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Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients

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Does the Relation of Blood Pressure to Coronary Heart Disease Risk Change With Aging?: The Framingham Heart Study

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Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women

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Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises

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Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises

Lakatta, E. G. (2003) · Circulation · doi:10.1161/01.cir.0000048894.99865.02 · Cited by 1,105

Effects of age and aerobic capacity on arterial stiffness in healthy adults.

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Microparticles Induce Cell Cycle Arrest Through Redox‐Sensitive Processes in Endothelial Cells: Implications in Vascular Senescence

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Tetrahydrobiopterin improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women

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Xanthine oxidase does not contribute to impaired peripheral conduit artery endothelium‐dependent dilatation with ageing

Eskurza, I., Kahn, Z. D., & Seals, D. R. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2005.102566 · Cited by 99

Nutritional strategies for healthy cardiovascular aging: Focus on micronutrients

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Exercise Training Stimulates Ischemia-Induced Neovascularization via Phosphatidylinositol 3-Kinase/Akt-Dependent Hypoxia-Induced Factor-1α Reactivation in Mice of Advanced Age

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Downregulation of dynamin-related protein 1 contributes to impaired autophagic flux and angiogenic function in senescent endothelial cells

Lin, J.-R., Shen, W.-L., Yan, C., & Gao, P.-J. (2015) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.115.305706 · Cited by 97

mTOR and Aging: An Old Fashioned Dress

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Uterine Artery Remodeling and Reproductive Performance Are Impaired in Endothelial Nitric Oxide Synthase-Deficient Mice1

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The Noninvasive Assessment of Vascular Aging

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Endothelial cell senescence and thrombosis: Ageing clots

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The Role of Oxidative Stress in the Aging Heart

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Ascorbic Acid Selectively Improves Large Elastic Artery Compliance in Postmenopausal Women

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Accelerated senescence of cord blood endothelial progenitor cells in premature neonates is driven by SIRT1 decreased expression

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Sex differences in vascular aging in response to testosterone

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Carotid intima-media thickness should not be referred to as subclinical atherosclerosis: A recommended update to the editorial policy at Atherosclerosis

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Aortic stiffness: pathophysiology, clinical implications, and approach to treatment

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The role of the paracrine/autocrine mediator endothelin‐1 in regulation of cardiac contractility and growth

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The effects of aging and exercise training on endothelin-1 vasoconstrictor responses in rat skeletal muscle arterioles

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Cellular Senescence Contributes to Large Elastic Artery Stiffening and Endothelial Dysfunction With Aging: Amelioration With Senolytic Treatment

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Role of endothelial NAD+deficiency in age-related vascular dysfunction

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Cholesterol, Lipids and Arterial Stiffness

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Age‐related changes in aortic 3D blood flow velocities and wall shear stress: Implications for the identification of altered hemodynamics in patients with aortic valve disease

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Effects of Relaxin on Arterial Dilation, Remodeling, and Mechanical Properties

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Correlates of vascular structure and function measures in asymptomatic young adults: The Bogalusa Heart Study

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Vascular endothelial ageing, heartbeat after heartbeat

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B6D2F1 Mice Are a Suitable Model of Oxidative Stress-Mediated Impaired Endothelium-Dependent Dilation With Aging

Lesniewski, L. A., Connell, M., Durrant, J., Folian, B. J., Anderson, M. C., Donato, A. J., & Seals, D. R. (2009) · The Journals of Gerontology Series A · doi:10.1093/gerona/gln049 · Cited by 90

Cardiometabolic determinants of mortality in a geriatric population: Is there a “reverse metabolic syndrome”?

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Angiotensin II Requires Zinc and Downregulation of the Zinc Transporters ZnT3 and ZnT10 to Induce Senescence of Vascular Smooth Muscle Cells

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SIRT 1‐mediated epigenetic downregulation of plasminogen activator inhibitor‐1 prevents vascular endothelial replicative senescence

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The impact of a naturalistic hands-free cellular phone task on heart rate and simulated driving performance in two age groups

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Resveratrol reduces vascular cell senescence through attenuation of oxidative stress by SIRT1/NADPH oxidase-dependent mechanisms

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Implications of Vascular Aging

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The roles of autophagy in vascular smooth muscle cells

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Role of Aldosterone and Mineralocorticoid Receptor in Cardiovascular Aging

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Perivascular adipose tissue in age-related vascular disease

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Epidemiology, Clinical Features, and Prognosis of Acute Myocardial Infarction in the Elderly

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Comparative effects of non-steroidal anti-inflammatory drugs (NSAIDs) on blood pressure in patients with hypertension

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A systematic literature review of the effect of carotid atherosclerosis on local vessel stiffness and elasticity

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Predictive Utility of Pulse Pressure and Other Blood Pressure Measures for Cardiovascular Outcomes

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Vascular aging: implications for cardiovascular disease and therapy

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Age-related ocular vascular changes

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Exercise intolerance in heart failure with preserved ejection fraction: more than a heart problem.

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Dietary potassium regulates vascular calcification and arterial stiffness

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Effects of Physical Activity on Cardiovascular and Noncardiovascular Outcomes in Older Adults

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Hydrogen sulfide prevents H2O2-induced senescence in human umbilical vein endothelial cells through SIRT1 activation

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Adaptation of pulmonary O2 uptake kinetics and muscle deoxygenation at the onset of heavy-intensity exercise in young and older adults

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Coenzyme Q10 Prevents Senescence and Dysfunction Caused by Oxidative Stress in Vascular Endothelial Cells

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Progesterone Increases Circulating Endothelial Progenitor Cells and Induces Neural Regeneration after Traumatic Brain Injury in Aged Rats

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Ethnicity and Arterial Stiffness

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Temporal trend and attributable risk factors of cardiovascular disease burden for adults 55 years and older in 204 countries/territories from 1990 to 2021: an analysis for the Global Burden of Disease Study 2021

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DNA damage, vascular senescence and atherosclerosis

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Nutrition and other lifestyle influences on arterial aging

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Sodium nitrite de-stiffening of large elastic arteries with aging: Role of normalization of advanced glycation end-products

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Does Wave Reflection Dominate Age-Related Change in Aortic Blood Pressure Across the Human Life Span?

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Pulse Pressure Is Inversely Related to Aortic Root Diameter Implications for the Pathogenesis of Systolic Hypertension

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Plasma Oxidized Low-Density Lipoprotein Levels and Arterial Stiffness in Older Adults

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MicroRNAs and Cardiovascular Diseases

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Pharmacotherapy in Older Adults with Cardiovascular Disease: Report from an American College of Cardiology, American Geriatrics Society, and National Institute on Aging Workshop

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Modulatory influence of sex hormones on vascular aging

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Dose-dependent increases in flow-mediated dilation following acute cocoa ingestion in healthy older adults

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Oral trehalose supplementation improves resistance artery endothelial function in healthy middle-aged and older adults

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Influence of Child and Adult Elevated Blood Pressure on Adult Arterial Stiffness

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Smooth Muscle Cell–Mineralocorticoid Receptor as a Mediator of Cardiovascular Stiffness With Aging

Kim, S. K., McCurley, A., DuPont, J. J., Aronovitz, M. A., Moss, M. E., Stillman, I. E., Karumanchi, S. A., Christou, D. D., & Jaffe, I. Z. (2018) · Hypertension · doi:10.1161/hypertensionaha.117.10437 · Cited by 84

Mitochondrial quality control: The role of mitophagy in aging

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Healthy lifestyle-based approaches for successful vascular aging

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Elevated Sodium and Dehydration Stimulate Inflammatory Signaling in Endothelial Cells and Promote Atherosclerosis

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Impact of age, sex and exercise on brachial and popliteal artery remodelling in humans

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Relationship Between Obesity and Obesity-Related Morbidities Weakens With Aging

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Age-related changes in plaque composition

van Oostrom, O., Velema, E., Schoneveld, A. H., de Vries, J. P. M., de Bruin, P. C., Seldenrijk, C. A., de Kleijn, D. P. V., Busser, E., Moll, F. L., Verheijen, J. H., et al. (2005) · Cardiovascular Pathology · doi:10.1016/j.carpath.2005.03.002 · Cited by 83

Drug Treatment of Hypertension: Focus on Vascular Health

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Accelerated Aging and Age-Related Diseases (CVD and Neurological) Due to Air Pollution and Traffic Noise Exposure

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Non-Invasive Methods for PWV Measurement in Blood Vessel Stiffness Assessment

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Urgent needs of caregiving in ageing populations with Alzheimer’s disease and other chronic conditions: Support our loved ones

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Involvement of endothelin‐1 in habitual exercise‐induced increase in arterial compliance

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All-Extremity Exercise Training Improves Arterial Stiffness in Older Adults

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Age-Related Vascular Changes Affect Turbulence in Aortic Blood Flow

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Autophagy and cardiovascular aging

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Mitochondrial quality control and age-associated arterial stiffening

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Imaging Insights on the Aorta in Aging

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Continuous Non-Invasive Blood Pressure Monitoring: A Methodological Review on Measurement Techniques

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A conserved KLF-autophagy pathway modulates nematode lifespan and mammalian age-associated vascular dysfunction

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The Effect of Aging on Relationships between Lean Body Mass and VO2max in Rowers

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Hydroxymethylglutaryl‐CoA Reductase Inhibitors in Older Persons with Acute Myocardial Infarction: Evidence for an Age–Statin Interaction

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Endothelial dysfunction and vascular disease in later life

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Mechanisms underlying enhanced cardiac excitation contraction coupling observed in the senescent sheep myocardium

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The role of insulin in the vascular contributions to age-related dementia

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The role of the endothelial glycocalyx in advanced age and cardiovascular disease

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Cardiac tissue remodeling in healthy aging: the road to pathology

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SIRT2 counteracts primate cardiac aging via deacetylation of STAT3 that silences CDKN2B

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Mechanisms of MicroRNAs in Atherosclerosis

Schober, A., & Weber, C. (2016) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-012615-044135 · Cited by 78

Efficacy of Cardioprotective ‘Conditioning’ Strategies in Aging and Diabetic Cohorts

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Arterial stiffness and 24h ambulatory blood pressure monitoring in young healthy volunteers: The early vascular ageing Aristotle University Thessaloniki Study (EVA–ARIS Study)

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Genes, physical fitness and ageing

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Aging-Associated Vascular Phenotype in Mutant Mice With Low Levels of BubR1

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Co-expression network analysis identified hub genes critical to triglyceride and free fatty acid metabolism as key regulators of age-related vascular dysfunction in mice

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Heterogeneous vasodilator responses of human limbs: influence of age and habitual endurance training

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Cardiovascular Disease in the Elderly

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Epidemiology, Pathophysiology, and Prognosis of Heart Failure in the Elderly

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Association Between Human Immunodeficiency Virus Infection and Stiffness of the Common Carotid Artery

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Melatonin: Protection against age-related cardiac pathology

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Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises. Part III: cellular and molecular clues to heart and arterial aging. Circulation

Lakatta, E. G., Levy, D. A., & Levy, D. A. (2015)

Aging and Cardiovascular Disease

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Aging of the Heart and Arteries: A Set-up for Cardiovascular Disease Leading to Heart Failure

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Aging’s Accomplice in Harming the Cardiovascular System

Wei, Y. (2020) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.120.315217

Aging Issues in Cardiology

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