The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Air Pollution and Cardiovascular Disease: A Statement for Healthcare Professionals From the Expert Panel on Population and Prevention Science of the American Heart Association
Abstract
Air pollution is a heterogeneous, complex mixture of gases, liquids, and particulate matter. Epidemiological studies have demonstrated a consistent increased risk for cardiovascular events in relation to both short- and long-term exposure to present-day concentrations of ambient particulate matter. Several plausible mechanistic pathways have been described, including enhanced coagulation/thrombosis, a propensity for arrhythmias, acute arterial vasoconstriction, systemic inflammatory responses, and the chronic promotion of atherosclerosis. The purpose of this statement is to provide healthcare professionals and regulatory agencies with a comprehensive review of the literature on air pollution and cardiovascular disease. In addition, the implications of these findings in relation to public health and regulatory policies are addressed. Practical recommendations for healthcare providers and their patients are outlined. In the final section, suggestions for future research are made to address a number of remaining scientific questions.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Heart rate variability: Standards of measurement, physiological interpretation, and clinical use
Malik, M., Bigger, J. T., Camm, A. J., Kleiger, R. E., Malliani, A., Moss, A. J., & Schwartz, P. J. (1996) · European Heart Journal · doi:10.1093/oxfordjournals.eurheartj.a014868 · Cited by 15,289
An association between air pollution and mortality in six U.S. cities
Dockery, D. W., Pope, C. A., Xu, X., Spengler, J. D., Ware, J. H., Fay, M. E., Ferris, B. G., & Speizer, F. E. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312093292401 · Cited by 8,018
Inflammation and Atherosclerosis
Libby, P., Ridker, P. M., & Maseri, A. (2002) · Circulation · doi:10.1161/hc0902.104353 · Cited by 7,724
Pope, C. A., Burnett, R. T., Thurston, G. D., Thun, M. J., Calle, E. E., Krewski, D., & Godleski, J. J. (2004) · Circulation · doi:10.1161/01.cir.0000108927.80044.7f · Cited by 2,592
Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage
Li, N., Sioutas, C., Cho, A., Schmitz, D., Misra, C., Sempf, J., Wang, M., Oberley, T., Froines, J., & Nel, A. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.6000 · Cited by 2,097
Passage of inhaled particles into the blood circulation in humans
Nemmar, A., Hoet, P. H. M., Vanquickenborne, B., Dinsdale, D., Thomeer, M., Hoylaerts, M. F., Vanbilloen, H., Mortelmans, L., & Nemery, B. (2002) · Circulation · doi:10.1161/hc0402.104118 · Cited by 1,719
Increased plasma viscosity during an air pollution episode: a link to mortality?
Peters, A., Döring, A., Wichmann, H.-E., & Koenig, W. (1997) · The Lancet · doi:10.1016/s0140-6736(97)01211-7 · Cited by 706
Smith, S. C., Blair, S. N., Bonow, R. O., Brass, L. M., Cerqueira, M. D., Dracup, K., Fuster, V., Gotto, A., Grundy, S. M., Miller, N. H., et al. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01682-5 · Cited by 691
Self-citationFichtlscherer, S., Rosenberger, G., Walter, D. H., Breuer, S., Dimmeler, S., & Zeiher, A. M. (2000) · Circulation · doi:10.1161/01.cir.102.9.1000 · Cited by 665
Smith, S. C., Blair, S. N., Bonow, R. O., Brass, L. M., Cerqueira, M. D., Dracup, K., Fuster, V., Gotto, A., Grundy, S. M., Miller, N. H., et al. (2001) · Circulation · doi:10.1161/hc3801.097475 · Cited by 661
Self-citation
Cited by
Toxic potential of materials at the nanolevel
Nel, A., Xia, T., Mädler, L., & Li, N. (2006) · Science · doi:10.1126/science.1114397 · Cited by 9,324
Brook, R. D., Rajagopalan, S., Pope, C. A., Brook, J. R., Bhatnagar, A., Diez-Roux, A. V., Holguin, F., Hong, Y., Luepker, R. V., Mittleman, M. A., et al. (2010) · Circulation · doi:10.1161/cir.0b013e3181dbece1 · Cited by 6,548
Self-citationThe Lancet Commission on pollution and health
Landrigan, P. J., Fuller, R., Acosta, N. J. R., Adeyi, O., Arnold, R., Basu, N. (., Baldé, A. B., Bertollini, R., Bose-O'Reilly, S., Boufford, J. I., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(17)32345-0 · Cited by 4,929
Long-term exposure to air pollution and incidence of cardiovascular events in women
Miller, K. A., Siscovick, D. S., Sheppard, L., Shepherd, K., Sullivan, J. H., Anderson, G. L., & Kaufman, J. D. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa054409 · Cited by 1,854
Long-term ozone exposure and mortality
Jerrett, M., Burnett, R. T., Pope, C. A., Ito, K., Thurston, G., Krewski, D., Shi, Y., Calle, E., & Thun, M. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0803894 · Cited by 1,602
Carnethon, M. R., Pu, J., Howard, G., Albert, M. A., Anderson, C. A. M., Bertoni, A. G., Mujahid, M. S., Palaniappan, L., Taylor, H. A., Willis, M., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000534 · Cited by 1,147
Self-citationCardiovascular Effects of Secondhand Smoke: Nearly as Large as Smoking
Barnoya, J., & Glantz, S. A. (2005) · Circulation · doi:10.1161/circulationaha.104.492215 · Cited by 939
Lackland, D. T., Roccella, E. J., Deutsch, A. F., Fornage, M., George, M. G., Howard, G., Kissela, B. M., Kittner, S. J., Lichtman, J. H., Lisabeth, L. D., et al. (2014) · Stroke · doi:10.1161/01.str.0000437068.30550.cf · Cited by 815
Self-citationChuang, K.-J., Chan, C.-C., Su, T.-C., Lee, C.-T., & Tang, C.-S. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200611-1627oc · Cited by 685
Rapid DNA methylation changes after exposure to traffic particles
Baccarelli, A., Wright, R. O., Bollati, V., Tarantini, L., Litonjua, A. A., Suh, H. H., Zanobetti, A., Sparrow, D., Vokonas, P. S., & Schwartz, J. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200807-1097oc · Cited by 653
Bollati, V, & Baccarelli, A. (2010) · Heredity · doi:10.1038/hdy.2010.2 · Cited by 590
Alegría-Torres, J. A., Baccarelli, A., & Bollati, V. (2011) · Epigenomics · doi:10.2217/epi.11.22 · Cited by 587
Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge
Stone, V., Miller, M. R., Clift, M. J. D., Elder, A., Mills, N. L., Møller, P., Schins, R. P. F., Vogel, U., Kreyling, W. G., Alstrup Jensen, K., et al. (2017) · Environmental Health Perspectives · doi:10.1289/ehp424 · Cited by 370
Bollati, V., Marinelli, B., Apostoli, P., Bonzini, M., Nordio, F., Hoxha, M., Pegoraro, V., Motta, V., Tarantini, L., Cantone, L., et al. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901300 · Cited by 347
Differentiating the effects of fine and coarse particles on daily mortality in Shanghai, China
Kan, H., London, S. J., Chen, G., Zhang, Y., Song, G., Zhao, N., Jiang, L., & Chen, B. (2007) · Environment International · doi:10.1016/j.envint.2006.12.001 · Cited by 339
Air Pollution, Oxidative Stress, and Alzheimer's Disease
Moulton, P. V., & Yang, W. (2012) · Journal of Environmental and Public Health · doi:10.1155/2012/472751 · Cited by 265
Barone-Adesi, F., Vizzini, L., Merletti, F., & Richiardi, L. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl201 · Cited by 240
Exposure to particulate air pollution and risk of deep vein thrombosis
Baccarelli, A., Martinelli, I., Zanobetti, A., Grillo, P., Hou, L.-F., Bertazzi, P. A., Mannucci, P. M., & Schwartz, J. (2008) · Archives of Internal Medicine · doi:10.1001/archinte.168.9.920 · Cited by 230
Fairweather, D., & Rose, N. R. (2007) · Methods · doi:10.1016/j.ymeth.2006.07.009 · Cited by 208
Gerlofs-Nijland, M. E., van Berlo, D., Cassee, F. R., Schins, R. P., Wang, K., & Campbell, A. (2010) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-7-12 · Cited by 170
Ozone and daily mortality in Shanghai, China
Zhang, Y., Huang, W., London, S. J., Song, G., Chen, G., Jiang, L., Zhao, N., Chen, B., & Kan, H. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.9014 · Cited by 163
Yang, C., Yang, H., Guo, S., Wang, Z., Xu, X., Duan, X., & Kan, H. (2012) · Science of The Total Environment · doi:10.1016/j.scitotenv.2012.03.036 · Cited by 161
Chow, C. K., Lock, K., Teo, K., Subramanian, S., McKee, M., & Yusuf, S. (2009) · International Journal of Epidemiology · doi:10.1093/ije/dyn258 · Cited by 160
Pulmonary ozone exposure induces vascular dysfunction, mitochondrial damage, and atherogenesis
Chuang, G. C., Yang, Z., Westbrook, D. G., Pompilius, M., Ballinger, C. A., White, C. R., Krzywanski, D. M., Postlethwait, E. M., & Ballinger, S. W. (2009) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00102.2009 · Cited by 145
Oudin, A., Segersson, D., Adolfsson, R., & Forsberg, B. (2018) · PLOS ONE · doi:10.1371/journal.pone.0198283 · Cited by 133
Nakane, H. (2012) · Environmental Health and Preventive Medicine · doi:10.1007/s12199-011-0252-8 · Cited by 101
Air pollution shortens life expectancy and health expectancy for older adults: the case of China
Wen, M., & Gu, D. (2012) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/gls094 · Cited by 94
Gawda, A., Majka, G., Nowak, B., Śróttek, M., Walczewska, M., & Marcinkiewicz, J. (2018) · Inflammation Research · doi:10.1007/s00011-018-1165-4 · Cited by 71
Maternal residential proximity to major roadways, birth weight, and placental DNA methylation
Kingsley, S. L., Eliot, M. N., Whitsel, E. A., Huang, Y.-T., Kelsey, K. T., Marsit, C. J., & Wellenius, G. A. (2016) · Environment International · doi:10.1016/j.envint.2016.03.020 · Cited by 88
Danger in the Air: Air Pollution and Cognitive Dysfunction
Cipriani, G., Danti, S., Carlesi, C., & Borin, G. (2018) · American Journal of Alzheimer's Disease & Other Dementias® · doi:10.1177/1533317518777859 · Cited by 77
Household Air Pollution from Solid Fuel Use: Evidence for Links to CVD
McCracken, J. P., Wellenius, G. A., Bloomfield, G. S., Brook, R. D., Tolunay, H. E., Dockery, D. W., Rabadan-Diehl, C., Checkley, W., & Rajagopalan, S. (2012) · Global Heart · doi:10.1016/j.gheart.2012.06.010 · Cited by 76
Self-citationDriving and Implantable Cardioverter-Defibrillator Shocks for Ventricular Arrhythmias
Albert, C. M., Rosenthal, L., Calkins, H., Steinberg, J. S., Ruskin, J. N., Wang, P., Muller, J. E., & Mittleman, M. A. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.06.059 · Cited by 61
Self-citationPrenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults
Breton, C. V., Mack, W. J., Yao, J., Berhane, K., Amadeus, M., Lurmann, F., Gilliland, F., McConnell, R., Hodis, H. N., Künzli, N., et al. (2016) · PLOS ONE · doi:10.1371/journal.pone.0150825 · Cited by 53
Climate change, air quality, and respiratory health: a focus on particle deposition in the lungs
Chang, J.-H., Lee, Y.-L., Chang, L.-T., Chang, T.-Y., Hsiao, T.-C., Chung, K. F., Ho, K. F., Kuo, H.-P., Lee, K.-Y., Chuang, K.-J., et al. (2023) · Annals of Medicine · doi:10.1080/07853890.2023.2264881 · Cited by 49
Indoor air pollution from biomass fuels: a major health hazard in developing countries
Oluwole, O., Otaniyi, O. O., Ana, G. A., & Olopade, C. O. (2012) · Journal of Public Health · doi:10.1007/s10389-012-0511-1 · Cited by 46
Jiang, Y., Li, J., Ren, F., Ji, C., Aniagu, S., & Chen, T. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.113331 · Cited by 46
Air pollution and fecundability: Results from a Danish preconception cohort study
Wesselink, A. K., Wang, T. R., Ketzel, M., Mikkelsen, E. M., Brandt, J., Khan, J., Hertel, O., Laursen, A. S. D., Johannesen, B. R., Willis, M. D., et al. (2022) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.12832 · Cited by 42
Particulate air pollution: Major research methods and applications in animal models
Sun, Q., & Shang, Y. (2018) · Environmental Disease · doi:10.4103/ed.ed_16_18 · Cited by 37
Ren, C., Baccarelli, A., Wilker, E., Suh, H., Sparrow, D., Vokonas, P., Wright, R., & Schwartz, J. (2010) · Journal of Epidemiology and Community Health · doi:10.1136/jech.2008.083295 · Cited by 37
Measuring the productivity impacts of energy-efficiency: The case of high-efficiency buildings
Chatterjee, S., & Ürge-Vorsatz, D. (2021) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2021.128535 · Cited by 36
Calderón-Garcidueñas, L., Mora-Tiscareño, A., Gómez-Garza, G., Carrasco-Portugal, M. D. C., Pérez-Guillé, B., Flores-Murrieta, F. J., Pérez-Guillé, G., Osnaya, N., Juárez-Olguín, H., Monroy, M. E., et al. (2009) · Toxicologic Pathology · doi:10.1177/0192623309340277 · Cited by 28
Lai, A., Chang, M. L., O'Donnell, R. P., Zhou, C., Sumner, J. A., & Hsiai, T. K. (2021) · Science of The Total Environment · doi:10.1016/j.scitotenv.2021.146464 · Cited by 25
Ichihara, S., Li, W., Omura, S., Fujitani, Y., Liu, Y., Wang, Q., Hiraku, Y., Hisanaga, N., Wakai, K., Ding, X., et al. (2016) · Journal of Nanoparticle Research · doi:10.1007/s11051-016-3340-2 · Cited by 16
Metadata
- Authors
- Brook, R. D., Franklin, B., Cascio, W., Hong, Y., Howard, G., Lipsett, M., Luepker, R., Mittleman, M., Samet, J., Smith, S. C., & Tager, I.
- Venue
- Circulation
- Published
- 2004-06
- Volume
- 109
- Issue
- 21
- Pages
- 2655-2671
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2116237065
- Cited by
- 2,380
- References
- 15
- FWCI
- 61.03
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.