A cytokine-mediated link between innate immunity, inflammation, and cancer

The hallmarks of cancer

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Inflammation and cancer

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Pathogen Recognition and Innate Immunity

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Inflammation and cancer: back to Virchow?

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Interleukin-10 and the Interleukin-10 Receptor

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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

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Toll-like receptors and innate immunity

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

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Are Markers of Systemic Inflammatory Response Useful in the Management of Patients With Neuroendocrine Neoplasms?

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Role of p53 in Regulating Radiation Responses

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Marine- and plant-derived ω-3 fatty acids differentially regulate prostate cancer cell proliferation

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The role of corticotropin-releasing hormone receptor 1 in the development of colitis-associated cancer in mouse model

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History of tuberculosis as an independent prognostic factor for lung cancer survival

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Micelles with Sheddable Dendritic Polyglycerol Sulfate Shells Show Extraordinary Tumor Targetability and Chemotherapy in Vivo

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Contribution of genetic factors to platinum-based chemotherapy sensitivity and prognosis of non-small cell lung cancer

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Stellera chamaejasme and its constituents induce cutaneous wound healing and anti-inflammatory activities

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Aflatoxin G1 induced TNF‐α‐dependent lung inflammation to enhance DNA damage in alveolar epithelial cells

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New insights into affinity proteins for HER2-targeted therapy: Beyond trastuzumab

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Cannabidiol and the Canonical WNT/β-Catenin Pathway in Glaucoma

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Tumor immunotherapy and multi-mode therapies mediated by medical imaging of nanoprobes

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The Interplay Between Inflammation and Stromal Components in Pancreatic Cancer

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Contribution du système immunitaire à l’efficacité des chimiothérapies anticancéreuses

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Myeloid-Derived Suppressor Cell Differentiation in Cancer: Transcriptional Regulators and Enhanceosome-Mediated Mechanisms

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Sparassis latifolia polysaccharides inhibit colon cancer in mice by modulating gut microbiota and metabolism

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Study of the Anti-Inflammatory Mechanism of β-Carotene Based on Network Pharmacology

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Brain-wide mapping of immune receptors uncovers a neuromodulatory role of IL-17E and the receptor IL-17RB

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In VitroAntiinflammatory Activity of a New Sesquiterpene Lactone Isolated fromSiegesbeckia glabrescens

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Praeruptorin a inhibits lipopolysaccharide‐induced inflammatory response in murine macrophages through inhibition of NF‐κB pathway activation

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Interleukin-16 (IL-16) gene polymorphisms in Iranian patients with colorectal cancer.

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Proteomic-Based Approaches for the Study of Cytokines in Lung Cancer

Marrugal, Á., Ojeda, L., Paz-Ares, L. G., Molina‐Pinelo, S., & Ferrer, I. (2016) · Disease Markers · doi:10.1155/2016/2138627 · Cited by 38

Transcriptional modulation of regulatory T cell development by novel regulators NR4As

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Impact of chemotactic factors and receptors on the cancer immune infiltrate: a bioinformatics study revealing homogeneity and heterogeneity among patient cohorts

Stoll, G., Pol, J. G., Soumelis, V., Zitvogel, L., & Kroemer, G. (2018) · OncoImmunology · doi:10.1080/2162402x.2018.1484980 · Cited by 38

Inflammatory mediators of prostate epithelial cells stimulated with Trichomonas vaginalis promote proliferative and invasive properties of prostate cancer cells

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Neuroprotective and Anti-inflammatory Effects of Pterostilbene Metabolites in Human Neuroblastoma SH-SY5Y and RAW 264.7 Macrophage Cells

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Peripherally-driven myeloid NFkB and IFN/ISG responses predict malignancy risk, survival, and immunotherapy regime in ovarian cancer

Sprooten, J., Vankerckhoven, A., Vanmeerbeek, I., Borràs, D., Berckmans, Y., Wouters, R., Laureano, R. S., Baert, T., Boon, L., Landolfo, C., et al. (2021) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2021-003609 · Cited by 38

Previous pulmonary tuberculosis enhances the risk of lung cancer: systematic reviews and meta-analysis

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The Serpin Saga; Development of a New Class of Virus Derived Anti-Inflammatory Protein Immunotherapeutics

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Interplay of broccoli/broccoli sprout bioactives with gut microbiota in reducing inflammation in inflammatory bowel diseases

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EGCG downregulates IL-1RI expression and suppresses IL-1-induced tumorigenic factors in human pancreatic adenocarcinoma cells

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Increased Intratumoral Interleukin 22 Levels and Frequencies of Interleukin 22–Producing CD4+ T Cells Correlate With Pancreatic Cancer Progression

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CCAAT Enhancer Binding Protein-β Regulates Matrix Metalloproteinase-1 Expression in Interleukin-1β–Stimulated A549 Lung Carcinoma Cells

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STAT3 and NF-κB are Simultaneously Suppressed in Dendritic Cells in Lung Cancer

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Tumor-Treating Fields Induce RAW264.7 Macrophage Activation Via NK-κB/MAPK Signaling Pathways

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Oxidative Stress and Inflammation Can Fuel Cancer

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Therapeutic perspective of thiosemicarbazones derivatives in inflammatory pathologies: A summary of in vitro/in vivo studies

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Diarylheptanoid–myricanone isolated from ethanolic extract of Myrica cerifera shows anticancer effects on HeLa and PC3 cell lines: signalling pathway and drug-DNA interaction

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Apoptosis Inhibition Can Be Threatening in Aβ-Induced Neuroinflammation, Through Promoting Cell Proliferation

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Erucin Exerts Anti-Inflammatory Properties in Murine Macrophages and Mouse Skin: Possible Mediation through the Inhibition of NFκB Signaling

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Interleukin‐37 improves T‐cell‐mediated immunity and chimeric antigen receptor T‐cell therapy in aged backgrounds

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Presence of S100A9-positive inflammatory cells in cancer tissues correlates with an early stage cancer and a better prognosis in patients with gastric cancer

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Tumour microenvironment of both early- and late-stage colorectal cancer is equally immunosuppressive

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Modulation of the NF-κB Pathway by Bordetella pertussis Filamentous Hemagglutinin

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Interdependent and independent multidimensional role of tumor microenvironment on hepatocellular carcinoma

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Relationship between Circulating Inflammation Proteins and Lung Cancer Diagnosis in the National Lung Screening Trial

Brown, D. W., Zingone, A., Yu, Y., Zhu, B., Candia, J., Cao, L., & Ryan, B. M. (2018) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-18-0598 · Cited by 36

A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls

Cohen-Lavi, L., Fiore-Gartland, A., Randolph, A. G., Panoskaltsis‐Mortari, A., Wong, S., Ralston, J., Wood, T., Seeds, R., Huang, Q. S., Webby, R. J., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01338 · Cited by 35

Albumin–globulin ratio is a predictive biomarker of antitumor effect of anti-PD-1 antibody in patients with non-small cell lung cancer

Nakanishi, Y., Masuda, T., Yamaguchi, K., Sakamoto, S., Horimasu, Y., Mimae, T., Nakashima, T., Miyamoto, S., Tsutani, Y., Iwamoto, H., et al. (2019) · International Journal of Clinical Oncology · doi:10.1007/s10147-019-01539-2 · Cited by 36

Histologic margins and the residual tumour classification scheme: Is it time to use a validated scheme in human oncology to standardise margin assessment in veterinary oncology?

Liptak, J. M. (2019) · Veterinary and Comparative Oncology · doi:10.1111/vco.12555 · Cited by 36

Myrislignan Attenuates Lipopolysaccharide‐induced Inflammation Reaction in Murine Macrophage Cells Through Inhibition of NF‐κB Signalling Pathway Activation

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Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis

Kawamata, S., Matsuzaki, K., Murata, M., Seki, T., Matsuoka, K., Iwao, Y., Hibi∥, T., & Okazaki, K. (2010) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21395 · Cited by 36

Vernolide-A, a sesquiterpene lactone fromVernonia cinerea,induces apoptosis in B16F-10 melanoma cells by modulating p53 and caspase-3 gene expressions and regulating NF-κB-mediated bcl-2 activation

Pratheeshkumar, P., & Kuttan, G. (2011) · Drug and Chemical Toxicology · doi:10.3109/01480545.2010.520017 · Cited by 36

Intra-tumoral IFN-γ-producing Th22 cells correlate with TNM staging and the worst outcomes in pancreatic cancer

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Association of immunologic markers from complete blood counts with the response to preoperative chemoradiotherapy and prognosis in locally advanced rectal cancer

Jung, S. W., Park, I. J., Oh, S. H., Yeom, S., Lee, J. L., Yoon, Y. S., Kim, C. W., Lim, S., Lee, J. B., Yu, C. S., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.15760 · Cited by 36

Inflammatory Events During Murine Squamous Cell Carcinoma Development

Gasparoto, T. H., de Oliveira, C. E., de Freitas, L. T., Pinheiro, C. R., Ramos, R. N., da Silva, A. L., Garlet, G. P., da Silva, J. S., & Campanelli, A. P. (2012) · Journal of Inflammation · doi:10.1186/1476-9255-9-46 · Cited by 35

The role of IL‐1β during human immunodeficiency virus type 1 infection

Yaseen, M. M., Abuharfeil, N. M., & Darmani, H. (2022) · Reviews in Medical Virology · doi:10.1002/rmv.2400 · Cited by 35

Cathepsin D promotes polarization of tumor-associated macrophages and metastasis through TGFBI-CCL20 signaling

Lee, S. G., Woo, S. M., Seo, S. U., Lee, C., Baek, M., Jang, S. H., Park, Z., Yook, S., Nam, J., & Kwon, T. K. (2024) · Experimental & Molecular Medicine · doi:10.1038/s12276-024-01163-9 · Cited by 35

Association of Interleukin-12 Polymorphisms and Serum IL-12p40 Levels with Osteosarcoma Risk

Wang, J., Nong, L.-G., Wei, Y., Qin, S., Zhou, Y., & Tang, Y. (2013) · DNA and Cell Biology · doi:10.1089/dna.2013.2098 · Cited by 37

Micronome revealed miR-19a/b as key regulator of SOCS3 during cancer related inflammation of oral squamous cell carcinoma

Christopher, A. F., Gupta, M., & Bansal, P. (2016) · Gene · doi:10.1016/j.gene.2016.08.044 · Cited by 35

Cancer-induced inflammation and inflammation-induced cancer in colon: a role for S1P lyase

Schwiebs, A., Juan, M. H. S., Schmidt, K. G., Wiercinska, E., Anlauf, M., Ottenlinger, F. M., Thomas, D., Elwakeel, E., Weigert, A., Farin, H. F., et al. (2019) · Oncogene · doi:10.1038/s41388-019-0758-x · Cited by 34

Anticancer IrIII–Aspirin Conjugates for Enhanced Metabolic Immuno‐Modulation and Mitochondrial Lifetime Imaging

Wu, X., Zheng, Y., Wang, F., Cao, J., Zhang, H., Zhang, D., Tan, C., Ji, L., & Mao, Z. (2019) · Chemistry - A European Journal · doi:10.1002/chem.201900851 · Cited by 37

Propolis Exerts an Anti-Inflammatory Effect on PMA-Differentiated THP-1 Cells via Inhibition of Purine Nucleoside Phosphorylase

Alqarni, A. M., Niwasabutra, K., Sahlan, M., Fearnley, H., Fearnley, J., Ferro, V. A., & Watson, D. G. (2019) · Metabolites · doi:10.3390/metabo9040075 · Cited by 35

The prognostic impact of traditional Chinese medicine monomers on tumor-associated macrophages in non-small cell lung cancer

Wan, L., Tan, Y. L., Jiang, M., & Hua, Q. (2019) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(19)30089-5 · Cited by 35

Over‐expression of IκB‐kinase‐ε (IKKε/IKKi) induces secretion of inflammatory cytokines in prostate cancer cell lines

Péant, B., Diallo, J., Dufour, F., Page, C. L., Delvoye, N., Fred Saad, C., & Mes‐Masson, A. (2009) · The Prostate · doi:10.1002/pros.20912 · Cited by 35

Indoor secondary organic aerosols formation from ozonolysis of monoterpene: An example of d-limonene with ammonia and potential impacts on pulmonary inflammations

Niu, X., Ho, S. S. H., Ho, K., Huang, Y. H., Cao, J., Shen, Z., Sun, J., Wang, X., Wang, Y., Lee, S., et al. (2016) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2016.11.018 · Cited by 35

The Dynamics of Interactions Among Immune and Glioblastoma Cells

Éder, K., & Kálmán, B. (2015) · NeuroMolecular Medicine · doi:10.1007/s12017-015-8362-x · Cited by 37

The relationship between hypoxia and Alzheimer’s disease: an updated review

Tao, B., Gong, W., Xu, C., Ma, Z., Mei, J., & Chen, M. (2024) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2024.1402774 · Cited by 36

Downregulation of nuclear factor-kappa B (NF-κB) pathway by silibinin in human monocytes challenged with Paracoccidioides brasiliensis

Castro, C. F. B., Nakaira-Takahagi, É., Golim, M. D. A., de Medeiros, L. T. L., Romão‐Veiga, M., Weel, I. C., & Peraçoli, M. T. S. (2010) · Life Sciences · doi:10.1016/j.lfs.2010.04.005 · Cited by 34

The association of interleukin-16 gene polymorphisms with IL-16 serum levels and risk of nasopharyngeal carcinoma in a Chinese population

Qin, X. Y., Peng, Q., Lao, X., Chen, Z., Yu, L., Lao, X., Mo, C., Sui, J., Wu, J., Zhai, L., et al. (2013) · Tumor Biology · doi:10.1007/s13277-013-1257-2 · Cited by 34

The therapeutic value of targeting inflammation in gastrointestinal cancers

Sun, B., & Karin, M. (2014) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2014.04.011 · Cited by 34

State of the Science: Stress, Inflammation, and Cancer

Payne, J. K. (2014) · Oncology nursing forum · doi:10.1188/14.onf.533-540 · Cited by 35

Viola yedoensisLiposoluble Fraction Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice

Li, W. J., Xie, J.-Y., Li, H., Zhang, Y., Cao, J., Cheng, Z., & Chen, D. (2012) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x12500747 · Cited by 34

Medroxyprogesterone Acetate Differentially Regulates Interleukin (IL)-12 and IL-10 in a Human Ectocervical Epithelial Cell Line in a Glucocorticoid Receptor (GR)-dependent Manner

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Carabrol suppresses LPS-induced nitric oxide synthase expression by inactivation of p38 and JNK via inhibition of I-κBα degradation in RAW 264.7 cells

Lee, H. J., Lim, H. J., Lee, D. Y., Jung, H., Kim, M.-R., Moon, D., Kim, K. I., Lee, M., & Ryu, J. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.12.073 · Cited by 34

2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione inhibits the growth and metastasis of breast carcinoma in mice

Chen, C., Nong, Z., Xie, Q., He, J., Wene, C., Tang, X., Chen, X., Huang, R., & Gao, Y. (2017) · Scientific Reports · doi:10.1038/s41598-017-07162-3 · Cited by 34

An inflammation-based cumulative prognostic score system in patients with diffuse large B cell lymphoma in rituximab era

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Ongoing and future directions in the management of metastatic colorectal cancer: Update on clinical trials

Advani, S., & Kopetz, S. (2019) · Journal of Surgical Oncology · doi:10.1002/jso.25441 · Cited by 35

NK cell‑produced IFN‑γ regulates cell growth and apoptosis of colorectal cancer by regulating IL‑15

Cui, F., Qu, D., Sun, R., Zhang, M., & Nan, K. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.8343 · Cited by 34

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Circulating Levels of TNF Receptor II Are Prognostic for Patients with Peripheral T-cell Non–Hodgkin Lymphoma

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IL‐32γ enhances TNF‐α‐induced cell death in colon cancer

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Topographical changes in extracellular matrix: Activation of TLR4 signaling and solid tumor progression.

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The role of inflammation in HPV infection of the Oesophagus

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Tumor Promoting or Tumor Suppressing of NF-κ B, a Matter of Cell Context Dependency

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Optical advances in skeletal imaging applied to bone metastases

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Pulmonary Tuberculosis and Lung Cancer Risk in Current Smokers: The Seoul Male Cancer Cohort Study

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Overall Survival and Clinicopathological Characteristics of Patients with Breast Cancer in Relation to the Expression Pattern of HER-2, IL-6, TNF-α and TGF-β1

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In vivo and in vitro anti-inflammatory effects of Zao-Jiao-Ci (the spine of Gleditsia sinensis Lam.) aqueous extract and its mechanisms of action

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Pharmacogenetic predictors of toxicity to platinum based chemotherapy in non-small cell lung cancer patients

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Increased expression of interleukin‐23 associated with progression of colorectal cancer

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Role of interleukin-12 gene polymorphisms in the onset risk of cancer: a meta-analysis

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Phosphatidylcholine regulates NF-κB activation in attenuation of LPS-induced inflammation: evidence from in vitro study

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Lactobacillus paracasei DTA81, a cholesterol‐lowering strain having immunomodulatory activity, reveals gut microbiota regulation capability in BALB/c mice receiving high‐fat diet

Tarrah, A., Cruz, B. C. D. S., Dias, R. S., Duarte, V. D. S., Pakroo, S., de Oliveira, L. L., Pelúzio, M. D. C. G., Corich, V., Giacomini, A., & de Paula, S. O. (2021) · Journal of Applied Microbiology · doi:10.1111/jam.15058 · Cited by 34

Cytokines – major molecular messengers orchestrate between inflammation and cancer

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The cytokines in tumor microenvironment: from cancer initiation-elongation-progression to metastatic outgrowth

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The role of pro-inflammatory cytokines in the pathogenesis and progression of neoplasms

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Pro-tumorigenic and Anti-tumorigenic Roles of Pro-inflammatory Cytokines in Cancer

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