A cytokine-mediated link between innate immunity, inflammation, and cancer

The hallmarks of cancer

Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219

Inflammation and cancer

Coussens, L. M., & Werb, Z. (2002) · Nature · doi:10.1038/nature01322 · Cited by 15,111

Pathogen Recognition and Innate Immunity

Akira, S., Uematsu, S., & Takeuchi, O. (2006) · Cell · doi:10.1016/j.cell.2006.02.015 · Cited by 11,976

Inflammation and cancer: back to Virchow?

Balkwill, F., & Mantovani, A. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04046-0 · Cited by 7,746

Interleukin-10 and the Interleukin-10 Receptor

Moore, K. W., de Waal Malefyt, R., Coffman, R. L., & O'Garra, A. (2001) · Annual Review of Immunology · doi:10.1146/annurev.immunol.19.1.683 · Cited by 6,737

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Hugot, J.-P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J.-P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., et al. (2001) · Nature · doi:10.1038/35079107 · Cited by 5,591

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

MANTOVANI, A., SOZZANI, S., LOCATI, M., ALLAVENA, P., & SICA, A. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(02)02302-5 · Cited by 5,528

Smad-dependent and Smad-independent pathways in TGF-β family signalling

Derynck, R., & Zhang, Y. E. (2003) · Nature · doi:10.1038/nature02006 · Cited by 5,498

Toll-like receptors and innate immunity

Medzhitov, R. (2001) · Nature Reviews Immunology · doi:10.1038/35100529 · Cited by 4,308

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Park, H., Li, Z., Yang, X. O., Chang, S. H., Nurieva, R., Wang, Y.-H., Wang, Y., Hood, L., Zhu, Z., Tian, Q., et al. (2005) · Nature Immunology · doi:10.1038/ni1261 · Cited by 4,265

Targeting Apoptosis Pathways in Cancer and Perspectives with Natural Compounds from Mother Nature

Millimouno, F. M., Dong, J., Liu, Y., Li, J., & Li, X. (2014) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-14-0136 · Cited by 276

Desired Turbulence? Gut-Lung Axis, Immunity, and Lung Cancer

Bingula, R., Filaire, M., Radosevic‐Robin, N., Bey, M., Berthon, J., Bernalier‐Donadille, A., Vasson, M., & Filaire, E. (2017) · Journal of Oncology · doi:10.1155/2017/5035371 · Cited by 279

Polymeric nanoparticles promote macrophage reversal from M2 to M1 phenotypes in the tumor microenvironment

Wang, Y., Lin, Y., Qiao, S., An, H., Ma, Y., Qiao, Z., Rajapaksha, R. P. Y. J., & Wang, H. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.09.034 · Cited by 268

Emerging avenues linking inflammation and cancer

Kundu, J. K., & Surh, Y. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.02.035 · Cited by 272

Facts and fiction of the relationship between preexisting tuberculosis and lung cancer risk: A systematic review

Liang, H., Li, X., Yu, X., Guan, P., Yin, Z., He, Q., & Zhou, B. (2009) · International Journal of Cancer · doi:10.1002/ijc.24636 · Cited by 263

Cancer and inflammation

Munn, L. L. (2016) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1370 · Cited by 273

The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis

Chen, G. Y., Shaw, M. H., Redondo, G., & Núñez, G. (2008) · Cancer Research · doi:10.1158/0008-5472.can-08-2061 · Cited by 261

Protective and therapeutic potential of ginger ( Zingiber officinale ) extract and [6]‐gingerol in cancer: A comprehensive review

de Lima, R. M. T., dos Reis, A. C., de Menezes, A. P. M., Santos, J. V. D. O., Filho, J. W. G. D. O., Ferreira, J. R. D. O., de Alencar, M. V. O. B., da Mata, A. M. O. F., Khan, I. N., Islam, M. A., et al. (2018) · Phytotherapy Research · doi:10.1002/ptr.6134 · Cited by 267

Development and validation of an immune gene-set based Prognostic signature in ovarian cancer

Shen, S., Wang, G., Zhang, R., Zhao, Y., Yu, H., Wei, Y., & Chen, F. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.12.054 · Cited by 254

Gender Disparity of Hepatocellular Carcinoma: The Roles of Sex Hormones

Yeh, S., & Chen, P. (2010) · Oncology · doi:10.1159/000315247 · Cited by 261

The Prodrug Platin‐A: Simultaneous Release of Cisplatin and Aspirin

Pathak, R., Marrache, S., Choi, J. H., Berding, T. B., & Dhar, S. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201308899 · Cited by 255

Neural circuitry and immunity

Pavlov, V. A., & Tracey, K. J. (2015) · Immunologic Research · doi:10.1007/s12026-015-8718-1 · Cited by 254

Interleukin (IL) 1β Induction of IL-6 Is Mediated by a Novel Phosphatidylinositol 3-Kinase-dependent AKT/IκB Kinase α Pathway Targeting Activator Protein-1

Cahill, C. M., & Rogers, J. T. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m707692200 · Cited by 254

Prognostic impact of tumour‐infiltrating B cells and plasma cells in colorectal cancer

Berntsson, J., Nodin, B., Eberhard, J., Micke, P., & Jirström, K. (2016) · International Journal of Cancer · doi:10.1002/ijc.30138 · Cited by 258

Cancer evolution: Darwin and beyond

Vendramin, R., Litchfield, K., & Swanton, C. (2021) · The EMBO Journal · doi:10.15252/embj.2021108389 · Cited by 269

Garlic: Nature's Protection Against Physiological Threats

Butt, M. S., Sultan, M. T., Butt, M., & Iqbal, J. (2009) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390802145344 · Cited by 252

Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer.

Yadav, V. R., Prasad, S., Sung, B., Kannappan, R., & Aggarwal, B. B. (2010) · Toxins · doi:10.3390/toxins2102428 · Cited by 320

Nuclear Factor κB Signaling Regulates Neuronal Morphology and Cocaine Reward

Russo, S. J., Wilkinson, M. B., Mazei‐Robison, M. S., Dietz, D., Maze, I. S., Krishnan, V., Renthal, W. R., Graham, A., Birnbaum, S. G., Green, T. A., et al. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.6173-08.2009 · Cited by 248

Cancer and the Complement Cascade

Rutkowski, M. J., Sughrue, M. E., Kane, A. J., Mills, S. A., & Parsa, A. T. (2010) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-10-0225 · Cited by 253

The Role of Inflammation in Lung Cancer

Gomes, M. P., Teixeira, A. L., Coelho, A., Araújo, A., & Medeiros, R. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-3-0348-0837-8_1 · Cited by 257

Regulation of macrophage function in tumors: the multifaceted role of NF-κB

Hagemann, T., Biswas, S. K., Lawrence, T., Sica, A., & Lewis, C. E. (2009) · Blood · doi:10.1182/blood-2008-12-172825 · Cited by 249

The role of Toll-like receptors in chronic inflammation

Drexler, S. K., & Foxwell, B. M. J. (2009) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2009.10.009 · Cited by 250

Breast and prostate cancer: more similar than different

Risbridger, G. P., Davis, I. D., Birrell, S. N., & Tilley, W. D. (2010) · Nature reviews. Cancer · doi:10.1038/nrc2795 · Cited by 248

Transforming growth factor-β and the hallmarks of cancer

Tian, M., Neil, J. R., & Schiemann, W. P. (2010) · Cellular Signalling · doi:10.1016/j.cellsig.2010.10.015 · Cited by 254

IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation

Hu, F., Song, D., Yan, Y., Huang, C., Shen, C., Lan, J., Chen, Y., Liu, A., Wu, Q., Sun, L., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23923-1 · Cited by 235

Bioactive components of garlic and their physiological role in health maintenance: A review

Santhosha, S. G., Jamuna, P., & Prabhavathi, S. N. (2013) · Food Bioscience · doi:10.1016/j.fbio.2013.07.001 · Cited by 242

Is interleukin‐1 a good or bad ‘guy’ in tumor immunobiology and immunotherapy?

Apte, R. N., & Voronov, E. (2008) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00615.x · Cited by 243

A Possible Change Process of Inflammatory Cytokines in the Prolonged Chronic Stress and Its Ultimate Implications for Health

Tian, R., Hou, G., Li, D., & Yuan, T. (2014) · The Scientific World JOURNAL · doi:10.1155/2014/780616 · Cited by 248

Lung adenocarcinoma distally rewires hepatic circadian homeostasis

Masri, S., Papagiannakopoulos, T., Kinouchi, K., Liu, Y., Cervantes, M., Baldi, P., Jacks, T., & Sassone-Corsi, P. (2016) · Cell · doi:10.1016/j.cell.2016.04.039 · Cited by 234

Serum amyloid A: An acute-phase protein involved in tumour pathogenesis

Malle, E., Sodin-Semrl, S., & Kovacevic, A. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8321-x · Cited by 229

The Spectrum of Achalasia: Lessons From Studies of Pathophysiology and High-Resolution Manometry

Kahrilas, P. J., & Boeckxstaens, G. E. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.08.038 · Cited by 236

Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model

Gamallat, Y., Meyiah, A., Kuugbee, E. D., Hago, A. M., Chiwala, G., Awadasseid, A., Bamba, D., Zhang, X., Shang, X., Luo, F., et al. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.07.001 · Cited by 232

The receptor RAGE: Bridging inflammation and cancer

Riehl, A., Németh, J., Angel, P. E., & Heß, J. (2009) · Cell Communication and Signaling · doi:10.1186/1478-811x-7-12 · Cited by 239

Citrullinated histone H3 as a novel prognostic blood marker in patients with advanced cancer

Thålin, C., Lundström, S., Seignez, C., Daleskog, M., Lundström, A., Henriksson, P., Helleday, T., Phillipson, M., Wallén, H., & Demers, M. (2018) · PLoS ONE · doi:10.1371/journal.pone.0191231 · Cited by 235

The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion

Liu, M., Sakamaki, T., Casimiro, M. C., Willmarth, N. E., Quong, A. A., Ju, X., Ojeifo, J. O., Jiao, X., Yeow, W.-S., Katiyar, S., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-0732 · Cited by 226

The Role of Curcumin in Modulating Colonic Microbiota During Colitis and Colon Cancer Prevention

McFadden, R.-M. T., Larmonier, C. B., Shehab, K. W., Midura‐Kiela, M. T., Ramalingam, R., Harrison, C. A., Besselsen, D. G., Chase, J., Caporaso, J. G., Jobin, C., et al. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000522 · Cited by 233

Inflammation in the context of oral cancer

Feller, L., Altini, M., & Lemmer, J. (2013) · Oral Oncology · doi:10.1016/j.oraloncology.2013.07.003 · Cited by 225

Propolis: An update on its chemistry and pharmacological applications

Hossain, R., Quispe, C., Khan, R. A., Saikat, A. S. M., Ray, P., Ongalbek, D., Yeskaliyeva, B. K., Jain, D., Smeriglio, A., Trombetta, D., et al. (2022) · Chinese Medicine · doi:10.1186/s13020-022-00651-2 · Cited by 246

Adoptive immunotherapy of cancer using CD4+ T cells

Muranski, P. J., & Restifo, N. P. (2009) · Current Opinion in Immunology · doi:10.1016/j.coi.2009.02.004 · Cited by 230

Oxidative Stress and Carbonyl Lesions in Ulcerative Colitis and Associated Colorectal Cancer

Wang, Z., Li, S., Cao, Y. W., Tian, X., Zeng, R., Liao, D., & Cao, D. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/9875298 · Cited by 228

TLR-signaling and proinflammatory cytokines as drivers of tumorigenesis

Korneev, K. V., Atretkhany, K. N., Drutskaya, M. S., Grivennikov, S. I., Kuprash, D. V., & Nedospasov, S. A. (2016) · Cytokine · doi:10.1016/j.cyto.2016.01.021 · Cited by 236

C-Reactive Protein and Risk of Lung Cancer

Chaturvedi, A. K., Caporaso, N. E., Katki, H. A., Wong, H., Chatterjee, N., Pine, S. R., Chanock, S. J., Goedert, J. J., & Engels, E. A. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.27.0454 · Cited by 221

Previous Lung Diseases and Lung Cancer Risk: A Pooled Analysis From the International Lung Cancer Consortium

Brenner, D. R., Boffetta, P., Duell, E. J., Bickeböller, H., Rosenberger, A., McCormack, V., Muscat, J. E., Yang, P., Wichmann, H. ‐., Brueske-Hohlfeld, I., et al. (2012) · American Journal of Epidemiology · doi:10.1093/aje/kws151 · Cited by 215

Nature meets nurture: molecular genetics of gastric cancer

Milne, A. N., Carneiro, F., O'Morain, C. A., & Offerhaus, G. J. A. (2009) · Human Genetics · doi:10.1007/s00439-009-0722-x · Cited by 212

The neutrophil gelatinase-associated lipocalin (NGAL), a NF-κB-regulated gene, is a survival factor for thyroid neoplastic cells

Iannetti, A., Pacifico, F., Acquaviva, R., Lavorgna, A., Crescenzi, E., Vascotto, C., Tell, G., Salzano, A. M., Scaloni, A., Vuttariello, E., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0710846105 · Cited by 210

Lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors

Kondo, M. (2010) · Immunological Reviews · doi:10.1111/j.1600-065x.2010.00963.x · Cited by 231

Peroxiredoxin 1 Stimulates Secretion of Proinflammatory Cytokines by Binding to TLR4

Riddell, J. R., Wang, X.-Y., Minderman, H., & Gollnick, S. O. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901945 · Cited by 206

Stat3-coordinated Lin-28–let-7–HMGA2 and miR-200–ZEB1 circuits initiate and maintain oncostatin M-driven epithelial–mesenchymal transition

Guo, L., Chen, C., Shi, M., Wang, F., Chen, X., Diao, D., Hu, M., Yu, M., Lu, Q., & Guo, N. (2013) · Oncogene · doi:10.1038/onc.2012.573 · Cited by 214

Anti-inflammatory activity of methanolic extracts from edible mushrooms in LPS activated RAW 264.7 macrophages

Moro, C., Palacios, I., Lozano, M., D’Arrigo, M., Guillamón, E., Villares, A., Martínez, J. A., & Garcia-Lafuente, A. M. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2011.07.049 · Cited by 208

Interleukin-6 induces fat loss in cancer cachexia by promoting white adipose tissue lipolysis and browning

Han, J. S., Meng, Q., Shen, L., & Wu, G. (2018) · Lipids in Health and Disease · doi:10.1186/s12944-018-0657-0 · Cited by 207

Gastric Cancer Stem Cells

Takaishi, S., Okumura, T., & Wang, T. C. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.15.2603 · Cited by 209

Ginger and its Health Claims: Molecular Aspects

Butt, M. S., & Sultan, M. T. (2011) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408391003624848 · Cited by 204

Exploring the link between microorganisms and oral cancer: A systematic review of the literature

Hooper, S. J., Wilson, M. J., & Crean, S. J. (2009) · Head & Neck · doi:10.1002/hed.21140 · Cited by 203

The Immunobiology of Mushrooms

Borchers, A. T., Krishnamurthy, A., Keen, C. L., Meyers, F. J., & Gershwin, M. E. (2008) · Experimental Biology and Medicine · doi:10.3181/0708-mr-227 · Cited by 202

Radiation, Inflammation, and Immune Responses in Cancer

Multhoff, G., & Radons, J. (2012) · Frontiers in Oncology · doi:10.3389/fonc.2012.00058 · Cited by 206

Analysis of the intricate relationship between chronic inflammation and cancer

Chai, E. Z. P., Siveen, K. S., Shanmugam, M. K., Arfuso, F., & Sethi, G. (2015) · Biochemical Journal · doi:10.1042/bj20141337 · Cited by 202

Tumor Ablation and Therapeutic Immunity Induction by an Injectable Peptide Hydrogel

Jin, H., Wan, C., Zou, Z., Zhao, G., Zhang, L., Geng, Y., Chen, T., Huang, A., Jiang, F., Feng, J., et al. (2018) · ACS Nano · doi:10.1021/acsnano.7b08148 · Cited by 201

Anti‑inflammatory effect of quercetin and galangin in LPS‑stimulated RAW264.7 macrophages and DNCB‑induced atopic dermatitis animal models

Lee, H. N., Shin, S. A., Choo, G. S., Kim, H. J., Park, Y. S., Kim, B. S., Kim, S. K., Cho, S. D., Nam, J., Choi, C., et al. (2017) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2017.3296 · Cited by 204

Cancers take their Toll—the function and regulation of Toll-like receptors in cancer cells

Chen, R. J., Alvero, A. B., Silasi, D.-A., Steffensen, K. D., & Mor, G. (2008) · Oncogene · doi:10.1038/sj.onc.1210907 · Cited by 202

Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression

Hedlund, M., Padler‐Karavani, V., Varki, N. M., & Varki, A. P. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803943105 · Cited by 204

Link between chronic inflammation and human papillomavirus-induced carcinogenesis (Review)

Fernandes, J. V., Fernandes, T. A. A. D. M., de Azevedo, J. C. V., Cobucci, R. N., de Carvalho, M. G. F., Andrade, V. S., & de Araújo, J. M. G. (2015) · Oncology Letters · doi:10.3892/ol.2015.2884 · Cited by 205

Roles of NF-κB in health and disease: mechanisms and therapeutic potential

Wong, E. T., & Tergaonkar, V. (2009) · Clinical Science · doi:10.1042/cs20080502 · Cited by 196

Lung Cancer and Chronic Obstructive Pulmonary Disease: Needs and Opportunities for Integrated Research

Punturieri, A., Szabo, E. M., Croxton, T. L., Shapiro, S. D., & Dubinett, S. M. (2009) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djp023 · Cited by 196

The TGF-β Paradox in Human Cancer: An Update

Tian, M., & Schiemann, W. P. (2009) · Future Oncology · doi:10.2217/14796694.5.2.259 · Cited by 200

The Immunomodulation and Anti-Inflammatory Effects of Garlic Organosulfur Compounds in Cancer Chemoprevention

Schäfer, G., & Kaschula, C. H. (2014) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/18715206113136660370 · Cited by 197

The immunotoxicity of graphene oxides and the effect of PVP-coating

Zhi, X., Fang, H., Bao, C., Shen, G., Zhang, J., Wang, K., Guo, S., Wan, T. Y., & Cui, D. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.03.024 · Cited by 196

Inflammaging and Cancer: A Challenge for the Mediterranean Diet

Ostan, R., Lanzarini, C., Pini, E., Scurti, M., Vianello, D., Bertarelli, C., Fabbri, C., Izzi, M., Palmas, M. G., Biondi, F., et al. (2015) · Nutrients · doi:10.3390/nu7042589 · Cited by 198

Non-Alcoholic Fatty Liver Disease and Extra-Hepatic Cancers

Sanna, C., Rosso, C., Marietti, M., & Bugianesi, E. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17050717 · Cited by 194

Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles

Qian, S., Golubnitschaja, O., & Zhan, X. (2019) · The EPMA Journal · doi:10.1007/s13167-019-00194-x · Cited by 194

Melanoma-Educated CD14+ Cells Acquire a Myeloid-Derived Suppressor Cell Phenotype through COX-2–Dependent Mechanisms

Mao, Y., Poschke, I. C., Wennerberg, E., de Coaña, Y. P., Brage, S. E., Schultz, I., Hansson, J., Masucci, G. V., Lundqvist, A., & Kiessling, R. W. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-4115 · Cited by 192

Peptide-based supramolecular hydrogels for local drug delivery

Zhang, Z., Ai, S., Yang, Z., & Li, X. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.05.010 · Cited by 196

Suppression of the inflammatory response by triterpenes isolated from the mushroom Ganoderma lucidum

Dudhgaonkar, S. P., Thyagarajan‐Sahu, A., & Slíva, D. (2009) · International Immunopharmacology · doi:10.1016/j.intimp.2009.07.011 · Cited by 193

TLRs: Linking inflammation and breast cancer

Bhatelia, K., Singh, K., & Singh, R. K. (2014) · Cellular Signalling · doi:10.1016/j.cellsig.2014.07.035 · Cited by 203

The tumor microenvironment in hepatocellular carcinoma (Review)

Libra, M. (2012) · International Journal of Oncology · doi:10.3892/ijo.2012.1408 · Cited by 188

Tumor-associated macrophages and the profile of inflammatory cytokines in oral squamous cell carcinoma

Costa, N. L., Valadares, M. C., de Souza, P. C., Mendonça, E. F., Oliveira, J. C., Silva, T. A., & Batista, A. C. (2012) · Oral Oncology · doi:10.1016/j.oraloncology.2012.09.012 · Cited by 188

ERK activation drives intestinal tumorigenesis in Apcmin/+ mice

Lee, S. H., Hu, L., González-Navajas, J. M., Seo, G. S., Shen, C., Brick, J., Herdman, S., Varki, N. M., Corr, M., Lee, J., et al. (2010) · Nature Medicine · doi:10.1038/nm.2143 · Cited by 188

Overweight and obesity: a review of their relationship to metabolic syndrome, cardiovascular disease, and cancer in South America

Aballay, L. R., Eynard, A. R., Díaz, M. D. P., Navarro, A., & Muñoz, S. E. (2013) · Nutrition Reviews · doi:10.1111/j.1753-4887.2012.00533.x · Cited by 195

Tumor-Educated CD11bhighIalow Regulatory Dendritic Cells Suppress T Cell Response through Arginase I

Liu, Q., Zhang, C., Sun, A., Zheng, Y., Wang, L., & Cao, X. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803926 · Cited by 186

Interplay between DNA repair and inflammation, and the link to cancer

Kidane, D., Chae, W. J., Czochor, J. R., Eckert, K. A., Glazer, P. M., Bothwell, A. L. M., & Sweasy, J. B. (2014) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2013.875514 · Cited by 191

Inflammatory signaling cascades and autophagy in cancer

Monkkonen, T., & Debnath, J. (2017) · Autophagy · doi:10.1080/15548627.2017.1345412 · Cited by 189

NLRP3 inflammasome-mediated cytokine production and pyroptosis cell death in breast cancer

Faria, S. S., Costantini, S., de Lima, V. C. C., Andrade, V. P., Rialland, M., Rébé, C., Budillon, A., & Magalhães, K. G. (2021) · Journal of Biomedical Science · doi:10.1186/s12929-021-00724-8 · Cited by 192

Biomolecular characterization of exosomes released from cancer stem cells: Possible implications for biomarker and treatment of cancer

Kumar, D., Gupta, D. K., Shankar, S., & Srivastava, R. K. (2014) · Oncotarget · doi:10.18632/oncotarget.2462 · Cited by 194

The IKK-related kinases: from innate immunity to oncogenesis

Clément, J.-F., Meloche, S., & Servant, M. J. (2008) · Cell Research · doi:10.1038/cr.2008.273 · Cited by 189

Molecular pathways and targets in cancer-related inflammation

Mantovani, A., Garlanda, C., & Allavena, P. (2010) · Annals of Medicine · doi:10.3109/07853890903405753 · Cited by 182

Association of Inflammation-Related and microRNA Gene Expression with Cancer-Specific Mortality of Colon Adenocarcinoma

Schetter, A. J., Nguyen, G. H., Bowman, E. D., Mathé, E. A., Yuen, S. T., Hawkes, J. E., Croce, C. M., Leung, S. Y., & Harris, C. C. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-0627 · Cited by 185

Structure-based Design of Pyridone–Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition

Reich, S., Sprengeler, P. A., Chiang, G. G., Appleman, J. R., Chen, J. W., Clarine, J., Eam, B., Ernst, J. T., Han, Q., Goel, V., et al. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b01795 · Cited by 188

Biomarkers for Immune Checkpoint Inhibitor-Mediated Tumor Response and Adverse Events

Nakamura, Y. (2019) · Frontiers in Medicine · doi:10.3389/fmed.2019.00119 · Cited by 185

Lifestyle Factors in Cancer Survivorship

Ligibel, J. A. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2012.42.0638 · Cited by 189

Pulmonary tuberculosis increases the risk of lung cancer

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