The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Effects of Antidepressant Treatment on Sleep EEG in Depression
Abstract
Sleep abnormalities associated with major depressive disorders include an early onset of rapid eye movement (REM) sleep, increased awakenings, reduced slow-wave sleep and increased light, non-restorative sleep. This paper presents a review of the effects of antidepressants on sleep electroencephalogram (EEG) in depression, including tricyclics (TCAs), and selective serotonin re-uptake inhibitors (SSRIs). Studies of the effects of nefazodone, a phenylpiperazine agent that has dual action on serotonin (5-HT 1A re-uptake inhibition and 5-HT 2 antagonism), are also included. In contrast to TCAs and SSRIs, nefazodone is a non-sedating antidepressant that improves sleep consolidation. Nefazodone also has little effect on REM latency or on total REM time, as reported for trimipramine, iprindole, moclobemide and bupropion. These findings suggest that antidepressant efficacy is not solely tied to REM sleep suppression.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Citations
Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Hobson, J. A. (1969) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(69)90021-2 · Cited by 5,215
Normal Human Sleep: An Overview
Carskadon, M. A., & Dement, W. C. (2005) · Elsevier eBooks · doi:10.1016/b0-72-160797-7/50009-4 · Cited by 1,190
Sleep Research in Affective Illness: State of the Art Circa 1987
Reynolds, C. F., & Kupfer, D. J. (1987) · SLEEP · doi:10.1093/sleep/10.3.199 · Cited by 467
Paradoxical sleep and its chemical/structural substrates in the brain
Jones, B. E. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90002-6 · Cited by 399
Schenck, C. H., Mahowald, M. W., Kim, S. W., O'Connor, K. A., & Hurwitz, T. D. (1992) · Sleep · doi:10.1093/sleep/15.3.226 · Cited by 261
Drug effects on REM sleep and on endogenous depression
Vogel, G. W., Buffenstein, A., Minter, K., & Hennessey, A. C. (1990) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80159-9 · Cited by 198
Fluoxetine and extrapyramidal side effects
Coulter, D. M., & Pillans, P. I. (1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.1.122 · Cited by 170
Microarchitectural findings in sleep EEG in depression: Diagnostic implications
Armitage, R. (1995) · Biological Psychiatry · doi:10.1016/0006-3223(94)00082-e · Cited by 122
Self-citationEffects of trazodone on the sleep of depressed subjects—a polygraphic study
Mouret, J., Lemoine, P., Minuit, M. P., Benkelfat, C., & Renardet, M. (1988) · Psychopharmacology · doi:10.1007/bf00172629 · Cited by 116
REM sleep enhancement by bupropion in depressed men
Nofzinger, E. A., Reynolds, C. F., Thase, M. E., Frank, E., Jennings, J. R., Fasiczka, A. L., Sullivan, L., & Kupfer, D. J. (1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.2.274 · Cited by 114
Extrapyramidal Symptoms with Selective Serotonin Reuptake Inhibitors
Arya, D. K. (1994) · The British Journal of Psychiatry · doi:10.1192/bjp.165.6.728 · Cited by 112
The Effects of Nefazodone on Sleep Architecture in Depression
Armitage, R., Rush, A. J., Trivedi, M., Cain, J., & Roffwarg, H. P. (1994) · Neuropsychopharmacology · doi:10.1038/npp.1994.14 · Cited by 102
Self-citationSaletu, B., Frey, R., Krupka, M., Anderer, P., Grfulberger, J., & See, W. R. (1991) · SLEEP · doi:10.1093/sleep/14.5.439 · Cited by 88
Fluvoxamine versus desipramine: Comparative polysomnographic effects
Kupfer, D. J., Perel, J. M., Pollock, B. G., Nathan, R. S., Grochocinski, V. J., Wilson, M. J., & McEachran, A. B. (1991) · Biological Psychiatry · doi:10.1016/0006-3223(91)90208-4 · Cited by 78
Comparison of effects of desipramine and amitriptyline on EEG sleep of depressed patients
Shipley, J. E., Kupfer, D. J., Griffin, S. J., Dealy, R. S., Coble, P. A., McEachran, A. B., Grochocinski, V. J., Ulrich, R., & Perel, J. M. (1985) · Psychopharmacology · doi:10.1007/bf00427316 · Cited by 70
Clomipramine and EEG sleep in depression
Kupfer, D. J., Ehlers, C. L., Pollock, B. G., Nathan, R. S., & Perel, J. M. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90158-3 · Cited by 68
Effects of paroxetine on human sleep.
Oswald, I., & Adám, K. (1986) · PubMed Central · Cited by 65
Fluoxetine and Oculomotor Activity during Sleep in Depressed Patients
Armitage, R. (1995) · Neuropsychopharmacology · doi:10.1016/0893-133x(94)00075-b · Cited by 60
Self-citationThe Effects of Fluoxetine on the Polysomnogram of Depressed Outpatients: A Pilot Study
Hendrickse, W. A., Roffwarg, H. P., Grannemann, B. D., Orsulak, P. J., Armitage, R., Cain, J. W., Battaglia, J., Debus, J. R., & Rush, A. J. (1994) · Neuropsychopharmacology · doi:10.1038/npp.1994.10 · Cited by 56
Self-citationShipley, J. E., Kupfer, D. J., Dealy, R. S., Griffin, S. J., Coble, P. A., McEachran, A. B., & Grochocinski, V. J. (1984) · Clinical Pharmacology and Therapeutics · doi:10.1038/clpt.1984.171 · Cited by 49
5‐HT2 receptor antagonism and slow‐wave sleep in major depression
Staner, L., Kempenaers, C., Simonnet, M. ‐., Fransolet, L., & Mendlewicz, J. (1992) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1992.tb03241.x · Cited by 45
Effect of a Reversible Monoamine Oxidase-A Inhibitor (Moclobemide) on Sleep of Depressed Patients
Monti, J. M. (1989) · British Journal of Psychiatry · doi:10.1192/s000712500029750x · Cited by 41
Gk, S., Filler, W., Ranft, W., & Zerbin, D. (1981) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1981.tb00734.x · Cited by 21
Flagged first, then by citations
Research works printed but not linked: 9
- ArmitageR. (1994). Sleep: biological rhythms and human performance. In RamachandranV.S. (ed.), Encyclopedia of human behaviour, Vol 4. Academic Press Inc. San Diego, CA, pp. 205–211
- Dorsey C.M., 1992, Sleep Res, 21, 55
- Dunleavy D.L., 1972, Br J Psychiatr, 28, 353
- Eison A.S., 1990, Psychochopharmacol Bull, 26, 311
- JouvetM., DeNoyerM., KitahamaK., SallonanonM. (1989). Slow wave sleep and indolamines. A hypothalamic target. In WauquierA., DugovicC. (eds), Slow wave sleep, physiologic and functional aspects. Raven Press New York, pp. 91–108
- Keck P.E., 1990, Sleep Res, 19, 66
- Oswald I., 1986, Br J Clin Pharmacol, 22, 97
- RushA.J., CainJ.W., RaeseJ., StewartR.S., WallerD.A., DebusJ. R. (1991). Neurobiological bases for psychiatric disorders. In RosenbergR.N. (ed.), Comprehensive neurology. Raven Press New York, pp. 555–603.
- Winkelman J., 1992, Sleep Res, 21, 78
Cited by
Sorted by citations
Serotonin control of sleep-wake behavior
Monti, J. M. (2011) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2010.11.003 · Cited by 614
The roles of dopamine and serotonin, and of their receptors, in regulating sleep and waking
Monti, J. M., & Jantos, H. (2008) · Progress in brain research · doi:10.1016/s0079-6123(08)00929-1 · Cited by 311
Manber, R., Rush, A. J., Thase, M. E., Arnow, B., Klein, D., Trivedi, M. H., Korenstein, S. G., Markowitz, J. C., Dunner, D. L., Munsaka, M., et al. (2003) · SLEEP · doi:10.1093/sleep/26.2.130 · Cited by 102
The Effects of Antidepressants on Sleep: A Review
Gursky, J. T., & Krahn, L. E. (2000) · Harvard Review of Psychiatry · doi:10.1080/hrp.8.6.298 · Cited by 77
The Effects of Antidepressants on Sleep in Patients with Depression
Armitage, R. (2000) · The Canadian Journal of Psychiatry · doi:10.1177/070674370004500903 · Cited by 71
Self-citationDepression and Sleep Disorders: Clinical Relevance, Economic Burden and Pharmacological Treatment
Brunello, N., Armitage, R., Feinberg, I., Holsboer‐Trachsler, E., Léger, D., Linkowski, P., Mendelson, W. B., Racagni, G., Saletu, B., Sharpley, A. L., et al. (2000) · Neuropsychobiology · doi:10.1159/000026680 · Cited by 68
Self-citationParasomnias and Antidepressant Therapy: A Review of the Literature
Kierlin, L., & Littner, M. R. (2011) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2011.00071 · Cited by 55
The Effect of Fluoxetine on Sleep EEG in Childhood Depression: A Preliminary Report
Armitage, R. (1997) · Neuropsychopharmacology · doi:10.1016/s0893-133x(97)00048-1 · Cited by 52
Self-citationEffects of long-term administration of nicotine and fluoxetine on sleep in depressed patients
Haro, R., & Drucker-Colı́n, R. (2004) · Archives of Medical Research · doi:10.1016/j.arcmed.2004.11.010 · Cited by 36
Pharmacology I: Effects on Sleep of Commonly Used ICU Medications
Weinhouse, G. L. (2008) · Critical Care Clinics · doi:10.1016/j.ccc.2008.02.008 · Cited by 32
Overview of psychiatric disorders and the role of newer antidepressants.
Ds, C., Grothe, D. R., Sl, S., Brady, K. T., Kaltsounis, J., Wright, C. W., Laird, L. K., & Rush, A. J. (2002) · PubMed · Cited by 23
A study of the brain structures involved in the acute effects of fluoxetine on REM sleep in the rat
Monti, J. M., & Jantos, H. (2005) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145704004511 · Cited by 20
Neuroimaging Profiles and the Differential Therapies of Depression
Thase, M. E. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.7.651 · Cited by 18
Sexual dysfunction in depression
Michael, A., & O’Keane, V. (2000) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/1099-1077(200007)15:5 · Cited by 104
Cholinergic Enhancement of REM Sleep from Sites in the Pons and Amygdala
Calvo, J. M., & Simón‐Arceo, K. (1998) · CRC Press eBooks · doi:10.1201/9780849331510.ch23 · Cited by 9
Pace-Schott, E. F. (2008) · Serotonin and Sleep: Molecular, Functional and Clinical Aspects · doi:10.1007/978-3-7643-8561-3_12 · Cited by 8
The effects of nefazodone on sleep in depressed patients and healthy controls
Armitage, R. (1999) · International Journal of Psychiatry in Clinical Practice · doi:10.3109/13651509909024767 · Cited by 3
Self-citationNefazodone in the treatment of patients with post-traumatic stress disorder
Sharpe, R. H., & Voris, J. C. (2002) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2.5.617 · Cited by 1
Metadata
- Authors
- Armitage, R.
- Affiliations
- The University of Texas Southwestern Medical Center (US)
- Corresponding author
- Armitage, Roseanne
- Venue
- Journal of Psychopharmacology
- Publisher
- SAGE Publications
- Published
- 1996-01
- Volume
- 10
- Issue
- 1_suppl
- Pages
- 22-25
- ISSN
- 0269-8811 (ISSN-L)
- 1461-7285
- OpenAlex
- W33987704
- Cited by
- 18
- References
- 24
- FWCI
- 1.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychopharmacology (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Keywords
- antidepressants, sleep EEG, depression, REM sleep, REM latency, slow-wave sleep, non-restorative sleep, tricyclic antidepressants, selective serotonin reuptake inhibitors, nefazodone, 5-HT1A receptor, 5-HT2 receptor antagonism, sleep consolidation, trimipramine, moclobemide, bupropion, iprindole
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
