The prion hypothesis in Parkinson's disease: braak to the future

Staging of brain pathology related to sporadic Parkinson’s disease

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Prions

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Novel Proteinaceous Infectious Particles Cause Scrapie

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Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

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Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

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Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease

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Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen

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Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein

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Gastric α-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology

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Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

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Parkinson's disease: a dual‐hit hypothesis

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Gastrointestinal Dysfunction in Parkinson’s Disease

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Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome)

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Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

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A Clinicopathologic Study of 100 Cases of Parkinson's Disease

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Gastrointestinal dysfunction in Parkinson's disease

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Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders

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Neuropathological Evidence of Graft Survival and Striatal Reinnervation after the Transplantation of Fetal Mesencephalic Tissue in a Patient with Parkinson's Disease

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α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

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Frequency of Bowel Movements and the Future Risk of Parkinson’s Disease

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Intravesicular Localization and Exocytosis of α-Synuclein and its Aggregates

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Prion-like transmission of protein aggregates in neurodegenerative diseases

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Prion-like mechanisms in neurodegenerative diseases

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Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation

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α-Synuclein Fibrillogenesis Is Nucleation-dependent

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Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction

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Pathoanatomy of Parkinson’s disease

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α-Synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy

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Presynaptic α-Synuclein Aggregates, Not Lewy Bodies, Cause Neurodegeneration in Dementia with Lewy Bodies

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Cognitive status correlates with neuropathologic stage in Parkinson disease

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Parkinson's disease: the presence of Lewy bodies in Auerbach's and Meissner's plexuses

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Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice

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Lewy bodies and parkinsonism in families with parkin mutations

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Assembly-dependent endocytosis and clearance of extracellular a-synuclein

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Alpha-synuclein in colonic submucosa in early untreated Parkinson’s disease

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Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years

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Colonic biopsies to assess the neuropathology of Parkinson's disease and its relationship with symptoms

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Aggresomes Formed by α-Synuclein and Synphilin-1 Are Cytoprotective

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The progression of pathology in longitudinally followed patients with Parkinson’s disease

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Prion-like acceleration of a synucleinopathy in a transgenic mouse model

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Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q

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The Seeds of Neurodegeneration: Prion-like Spreading in ALS

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Neuron‐to‐neuron transmission of α‐synuclein fibrils through axonal transport

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Evidence that incidental Lewy body disease is pre-symptomatic Parkinson’s disease

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Applicability of current staging/categorization of α-synuclein pathology and their clinical relevance

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α‐Synuclein pathology of the spinal and peripheral autonomic nervous system in neurologically unimpaired elderly subjects

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α‐Synuclein pathology does not predict extrapyramidal symptoms or dementia

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Lewy-body formation is an aggresome-related process: a hypothesis

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Seeding induced by α‐synuclein oligomers provides evidence for spreading of α‐synuclein pathology

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α‐Synuclein oligomers and clinical implications for Parkinson disease

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Transplanted dopaminergic neurons develop PD pathologic changes: A second case report

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Nanomedicine in the diagnosis and therapy of neurodegenerative disorders

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Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo

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Is Parkinson's disease a prion disorder?

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Familial juvenile Parkinsonism.

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Familial juvenile parkinsonism

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Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations

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Patterns and stages of α-synucleinopathy

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Degeneration of Cardiac Sympathetic Nerve Begins in the Early Disease Process of Parkinson’s Disease

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A critical reappraisal of current staging of Lewy-related pathology in human brain

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Pathological lesions in colonic biopsies during Parkinson’s disease

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The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of α‐synuclein staging

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Alpha‐Synuclein Stimulation of Astrocytes: Potential Role for Neuroinflammation and Neuroprotection

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Contribution of somal Lewy bodies to neuronal death

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Oligodendroglial Microtubular Tangles in Olivopontocerebellar Atrophy

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Parkinson's Disease-associated α-Synuclein Is More Fibrillogenic than β- and γ-Synuclein and Cannot Cross-seed Its Homologs

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Poor and protracted myelination as a contributory factor to neurodegenerative disorders

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Induction of neuronal death by α‐synuclein

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Milestones in PD genetics

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Spinal cord lesions in sporadic Parkinson’s disease

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Lewy pathology is not the first sign of degeneration in vulnerable neurons in Parkinson disease

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Characterisation of isolated α-synuclein filaments from substantia nigra of Parkinson's disease brain

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Disentangling the Relationship between Lewy Bodies and Nigral Neuronal Loss in Parkinson's Disease

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Brain stem pathology in Parkinson's disease: An evaluation of the Braak staging model

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Incidence and Extent of Lewy Body-Related α-Synucleinopathy in Aging Human Olfactory Bulb

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Preliminary diagnosis of Parkinson's disease by olfactory bulb pathology

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Regional differences in the severity of Lewy body pathology across the olfactory cortex

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Signs of Degeneration in 12–22-Year Old Grafts of Mesencephalic Dopamine Neurons in Patients with Parkinson's Disease

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Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy

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Conversion of Wild-type α-Synuclein into Mutant-type Fibrils and Its Propagation in the Presence of A30P Mutant

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Alpha‐synuclein pathology in the olfactory pathways of dementia patients

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The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease

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Olfactory pathogenesis of idiopathic Parkinson disease revisited

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Parallel manifestations of neuropathologies in the enteric and central nervous systems

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Generalization of the Prion Hypothesis to Other Neurodegenerative Diseases: An Imperfect Fit

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Do neuronal inclusions kill the cell?

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