Cognitive–behavioural group treatment for a range of functional somatic syndromes: Randomised trial
Open accessAbstract
Background: Many specialty-specific functional somatic syndrome diagnoses exist to describe people who are experiencing so-called medically unexplained symptoms. Although cognitive–behavioural therapy can be effective in the management of such syndromes, it is rarely available. A cognitive–behavioural therapy suitable for group treatment of people with different functional somatic syndromes could address this problem. Aims: To test the efficacy of a cognitive–behavioural therapy (Specialised Treatment for Severe Bodily Distress Syndromes, STreSS) designed for patients with a range of severe functional somatic syndromes. Method: A randomised controlled trial (clinicaltrials.gov, NCT00132197) compared STreSS (nine 3.5 h sessions over 4 months,n= 54) with enhanced usual care (management by primary care physician or medical specialist,n= 66). The primary outcome was improvement in aggregate score on subscales of the 36-item Short Form Health Survey (physical functioning, bodily pain and vitality) at 16 months. Results: Participants receiving STreSS had a greater improvement on the primary outcome (adjusted mean difference 4.0, 95% CI 1.4–6.6,P= 0.002) and on most secondary outcomes. Conclusions: In the management of functional somatic syndromes, a cognitive–behavioural group treatment was more effective than enhanced usual care.
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Based on previous studies, the proportion experiencing a minimum of a 4-point improvement at the primary outcome, the aggregate score, is estimated to be 35-50% in the intervention group and 10-25% in the active control group.
“Based on previous studies, we estimate the proportion experiencing a minimum of a 4-point improvement at the primary outcome, the aggregate score, to be 35–50% in the intervention group and 10–25% in the active control group [[17], [18], [19], [20]].”
From Internet-delivered treatment for patients suffering from severe functional somatic disorders: Protocol for a randomized controlled trial (2023) · cites this paper as [17]
The Outcome measures and Secondary outcomes sections define response as at least a 4-point improvement in the SF-36 aggregate score and report a higher response rate with STreSS than with enhanced usual care. Our copy gives a relative risk of 1.8 and a number needed to treat of 5, but does not provide the group-specific percentages needed to verify the estimated ranges of 35–50% and 10–25%. (LLM, conf=0.77)
Experimental — accuracy not yet measuredClinical trials have provided evidence for an effect of psychological interventions for functional somatic disorder multi-organ type.
“A number of clinical trials have provided evidence for an effect of psychological interventions for FSD multi-organ type [[17], [18], [19]].”
From Internet-delivered treatment for patients suffering from severe functional somatic disorders: Protocol for a randomized controlled trial (2023) · cites this paper as [17]
The aggregate physical health score has previously been used in an RCT with group-based CBT for adults with multiple FSS, i.e. multi-organ BDS.
“The aggregate score has previously been used in an RCT with group-based CBT for adults with multiple FSS, i.e. multi-organ BDS [37].”
From Feasibility of group-based acceptance and commitment therapy for adolescents (AHEAD) with multiple functional somatic syndromes: A pilot study (2020) · cites this paper as [37]
In adults with multiple FSS, a generic group-based treatment approach has been found effective regardless of main symptom.
“In adults with multiple FSS, a generic group-based treatment approach has been found effective regardless of main symptom [37].”
From Feasibility of group-based acceptance and commitment therapy for adolescents (AHEAD) with multiple functional somatic syndromes: A pilot study (2020) · cites this paper as [37]
The SF-36 aggregate score has previously been used as the primary outcome in a comparable trial in adults due to well-known psychometric problems with the existing physical component score (PCS) and based on the rationale that these three subscales have shown to be key domains affected in this patient group.
“This score has previously been used as the primary outcome in a comparable trial in adults39 due to well-known psychometric problems with the existing physical component score (PCS)73 and based on the rationale that these three subscales have shown to be key domains affected in this patient group.74”
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Self-citationMedically Unexplained Symptoms and Attachment Theory: The BodyMind Approach®
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Self-citationNetwork analysis of persistent somatic symptoms in two clinical patient samples
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Self-citationA cognitive behavioural group treatment for somatic symptom disorder: a pilot study
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Is psychotherapy for functional somatic syndromes harmful? A mixed methods study on negative effects
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The use of prescription medication in 239 patients with multiple functional somatic syndromes
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Self-citationMoving on: the BodyMind Approach<sup>TM</sup>for medically unexplained symptoms
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Somatoforme Störungen – somatoforme Belastungsstörung und verwandte Störungen
Kapfhammer, H. (2017) · Springer eBooks · doi:10.1007/978-3-662-49295-6_74 · Cited by 8 · see citing works
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Role of mental health professionals in the management of functional somatic symptoms in primary care
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“Furthermore, participants should have had an affiliation to the labour market or educational Abbreviations: FSD Functional somatic disorders FSS Functional somatic syndromes RCT Randomized controlled trial CBT Cognitive Behavioural Therapy DeFuD The Department for Functional Disorders AUH Aarhus University Hospital PH…”
MethodInfluentialSelf-citationPredictors of non-responding in short-term psychodynamic group therapy
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Can the pain field learn from the functional somatic disorder field?
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Patients with severe ME/CFS need hope and expert multidisciplinary care
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Zur Bedeutung der Gruppenleitung für therapeutische Prozesse in der Gruppe
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A nationwide healthcare program for functional somatic disorders (FSD) in Denmark
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- Authors
- Schröder, A., Rehfeld, E., Ørnbøl, E., Sharpe, M., Licht, R. W., & Fink, P.
- Affiliations
- Aarhus University Hospital (DK)
- University of Oxford (GB)
- Corresponding author
- Schröder, Andreas
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2012-06
- Volume
- 200
- Issue
- 6
- Pages
- 499-507
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2160493942
- Cited by
- 95
- References
- 46
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 2 · 2023: 6 · 2022: 7 · 2021: 6 · 2020: 9 · 2019: 7 · 2018: 8 · 2017: 15 · 2016: 9 · 2015: 8 · 2014: 5 · 2013: 1 · 2012: 4
- FWCI
- 4.09
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Aarhus Universitet
- Aarhus Universitetshospital
- A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal
- Region Midtjylland
- Fonden til Lægevidenskabens Fremme
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- functional somatic syndromes, cognitive behavioral therapy, group therapy, medically unexplained symptoms, stress, physical function, bodily pain, vitality, usual care comparison, primary care
- MeSH terms
- Adult, Female, Health Status, Humans, Male, Somatoform Disorders, Syndrome, Cognitive Behavioral Therapy, Treatment Outcome
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