Emerging role of Toll-like receptors in atherosclerosis

Atherosclerosis--an inflammatory disease

Ross, R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901143400207 · Cited by 21,725 · see citing works

TLR4 links innate immunity and fatty acid-induced insulin resistance

Shi, H., Kokoeva, M. V., Inouye, K., Tzameli, I., Yin, H., & Flier, J. S. (2006) · Journal of Clinical Investigation · doi:10.1172/jci28898 · Cited by 3,690 · see citing works

Points of control in inflammation

Nathan, C. (2002) · Nature · doi:10.1038/nature01320 · Cited by 2,738 · see citing works

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

Lotze, M. T., & Tracey, K. J. (2005) · Nature reviews. Immunology · doi:10.1038/nri1594 · Cited by 2,490 · see citing works

A mechanosensory complex that mediates the endothelial cell response to fluid shear stress

Tzima, E., Irani-Tehrani, M., Kiosses, W. B., Dejana, E., Schultz, D., Engelhardt, B., Cao, G., DeLisser, H. M., & Schwartz, M. A. (2005) · Nature · doi:10.1038/nature03952 · Cited by 1,738 · see citing works

Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex

Ohashi, K., Burkart, V., Flohé, S. B., & Kolb, H. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.2.558 · Cited by 1,607 · see citing works

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

Jiang, D., Liang, J., Fan, J., Yu, S., Chen, S., Luo, Y., Prestwich, G. D., Mascarenhas, M. M., Garg, H. G., Quinn, D. A., et al. (2005) · Nature Medicine · doi:10.1038/nm1315 · Cited by 1,401 · see citing works

Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4

Termeer, C., Benedix, F., Sleeman, J., Fieber, C., Voith, U., Ahrens, T., Miyake, K., Freudenberg, M., Galanos, C., & Simon, J. C. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20001858 · Cited by 1,378 · see citing works

The Extra Domain A of Fibronectin Activates Toll-like Receptor 4

Okamura, Y., Watari, M., Jerud, E. S., Young, D. W., Ishizaka, S. T., Rose, J., Chow, J. C., & Strauss, J. F. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100099200 · Cited by 1,217 · see citing works

Toll-like Receptor 9–mediated Recognition of Herpes Simplex Virus-2 by Plasmacytoid Dendritic Cells

Lund, J. M., Sato, A., Akira, S., Medzhitov, R. M., & Iwasaki, A. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030162 · Cited by 1,197 · see citing works

Reversing established sepsis with antagonists of endogenous high-mobility group box 1

Yang, H., Ochani, M., Li, J., Qiang, X., Tanovic, M., Harris, H. E., Susarla, S. M., Ulloa, L., Wang, H., DiRaimo, R., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2434651100 · Cited by 1,126 · see citing works

Toll-like receptors in systemic autoimmune disease

Marshak-Rothstein, A. (2006) · Nature Reviews Immunology · doi:10.1038/nri1957 · Cited by 1,116 · see citing works

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

Michelsen, K. S., Wong, M. H., Shah, P. K., Zhang, W., Yano, J., Doherty, T. M., Akira, S., Rajavashisth, T. B., & Arditi, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403249101 · Cited by 1,019 · see citing works

High mobility group box 1 protein interacts with multiple Toll-like receptors

Park, J. S., Gamboni-Robertson, F., He, Q., Svetkauskaite, D., Kim, J., Strassheim, D., Sohn, J.-W., Yamada, S., Maruyama, I., Banerjee, A. M., et al. (2005) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00401.2005 · Cited by 934 · see citing works

Toll-Like Receptor 4-Dependent Activation of Dendritic Cells by β-Defensin 2

Biragyn, A., Ruffini, P. A., Leifer, C. A., Klyushnenkova, E., Shakhov, A., Chertov, O., Shirakawa, A., Farber, J. M., Segal, D. M., Oppenheim, J. J., et al. (2002) · Science · doi:10.1126/science.1075565 · Cited by 904 · see citing works

Role of the Toll-like Receptor 4/NF-κB Pathway in Saturated Fatty Acid–Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages

Suganami, T., Tanimoto-Koyama, K., Nishida, J., Itoh, M., Yuan, X., Mizuarai, S., Kotani, H., Yamaoka, S., Miyake, K., Aoe, S., et al. (2006) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000251608.09329.9a · Cited by 806 · see citing works

Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

Parmar, K. M. (2005) · Journal of Clinical Investigation · doi:10.1172/jci24787 · Cited by 705 · see citing works

Endogenous ligands of Toll-like receptors

Tsan, M., & Gao, B. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0304127 · Cited by 683 · see citing works

Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature

Dai, G., Mofrad, M. R. K., Natarajan, S., Zhang, Y., Vaughn, S., Blackman, B. R., Kamm, R. D., García‐Cardeña, G., & Gimbrone, M. A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406073101 · Cited by 668 · see citing works

Receptor-Mediated Monitoring of Tissue Well-Being Via Detection of Soluble Heparan Sulfate by Toll-Like Receptor 4

Johnson, G. B., Brunn, G. J., Kodaira, Y., & Platt, J. L. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.10.5233 · Cited by 648 · see citing works

Mechanisms of disease: genetic causes of familial hypercholesterolemia

Soutar, A. K., & Naoumova, R. P. (2007) · Nature Clinical Practice Cardiovascular Medicine · doi:10.1038/ncpcardio0836 · Cited by 608 · see citing works

Accelerated atherosclerosis: An extraarticular feature of rheumatoid arthritis?

Doornum, S. V., McColl, G., & Wicks, I. P. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10089 · Cited by 605 · see citing works

Modulation of atherosclerosis in mice by Toll-like receptor 2

Mullick, A. E. (2005) · Journal of Clinical Investigation · doi:10.1172/jci25482 · Cited by 549 · see citing works

Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism

Castrillo, A., Joseph, S. B., Vaidya, S. A., Haberland, M. E., Fogelman, A. M., Cheng, G., & Tontonoz, P. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00384-8 · Cited by 488 · see citing works

Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1

Nauli, S. M., Kawanabe, Y., Kaminski, J. J., Pearce, W. J., Ingber, D. E., & Zhou, J. (2008) · Circulation · doi:10.1161/circulationaha.107.710111 · Cited by 466 · see citing works

Cutting Edge: Cell Surface Expression and Lipopolysaccharide Signaling Via the Toll-Like Receptor 4-MD-2 Complex on Mouse Peritoneal Macrophages

Akashi, S., Shimazu, R., Ogata, H., Nagai, Y., Takeda, K., Kimoto, M., & Miyake, K. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.7.3471 · Cited by 459 · see citing works

Minimally Modified LDL Binds to CD14, Induces Macrophage Spreading via TLR4/MD-2, and Inhibits Phagocytosis of Apoptotic Cells

Miller, Y. I., Viriyakosol, S., Binder, C. J., Feramisco, J. R., Kirkland, T. N., & Witztum, J. L. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209634200 · Cited by 398 · see citing works

Response of Human Pulmonary Epithelial Cells to Lipopolysaccharide Involves Toll-like Receptor 4 (TLR4)-dependent Signaling Pathways

Guillot, L., Medjane, S., Le-Barillec, K., Balloy, V., Danel, C. J., Chignard, M., & Si‐Tahar, M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m305790200 · Cited by 360 · see citing works

Mechanisms of Disease: atherosclerosis in autoimmune diseases

Sherer, Y., & Shoenfeld, Y. (2006) · Nature Clinical Practice Rheumatology · doi:10.1038/ncprheum0092 · Cited by 357 · see citing works

Successful treatment of collagen‐induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity

Kokkola, R., Li, J., Sundberg, E., Aveberger, A.-C., Palmblad, K., Yang, H., Tracey, K. J., Andersson, J., & Harris, H. E. (2003) · Arthritis & Rheumatism · doi:10.1002/art.11161 · Cited by 325 · see citing works

Vessel-Specific Toll-Like Receptor Profiles in Human Medium and Large Arteries

Pryshchep, O., Ma-Krupa, W., Younge, B. R., Goronzy, J. J., & Weyand, C. M. (2008) · Circulation · doi:10.1161/circulationaha.108.789172 · Cited by 322 · see citing works

Hemodynamic Shear Stresses in Mouse Aortas

Suo, J., Ferrara, D. E., Sorescu, D., Guldberg, R. E., Taylor, W. R., & Giddens, D. P. (2006) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000253492.45717.46 · Cited by 294 · see citing works

Biomechanical Forces in Atherosclerosis-Resistant Vascular Regions Regulate Endothelial Redox Balance via Phosphoinositol 3-Kinase/Akt-Dependent Activation of Nrf2

Dai, G., Vaughn, S., Zhang, Y., Wang, E. T., García‐Cardeña, G., & Gimbrone, M. A. (2007) · Circulation Research · doi:10.1161/circresaha.107.152942 · Cited by 245 · see citing works

Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

Mullick, A. E., Soldau, K., Kiosses, W. B., Bell, T. A., Tobias, P. S., & Curtiss, L. K. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20071096 · Cited by 223 · see citing works

NATURAL HISTORY AND RISK FACTORS OF ATHEROSCLEROSIS IN CHILDREN AND YOUTH: THE PDAY STUDY

Zieske, A. W., Malcom, G. T., & Strong, J. P. (2002) · Fetal and Pediatric Pathology · doi:10.1080/15227950252852104 · Cited by 219 · see citing works

TLR Signaling: An Emerging Bridge from Innate Immunity to Atherogenesis

Michelsen, K. S., Doherty, T. M., Shah, P. K., & Arditi, M. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.10.5901 · Cited by 211 · see citing works

Toll-Like Receptor 4 Is Involved in Outward Arterial Remodeling

Hollestelle, S. C. G., de Vries, M. R., van Keulen, J. K., Schoneveld, A. H., Vink, A., Strijder, C. F., van Middelaar, B. J., Pasterkamp, G., Quax, P. H. A., & de Kleijn, D. P. V. (2003) · Circulation · doi:10.1161/01.cir.0000109140.51366.72 · Cited by 197 · see citing works

Primary cilia sensitize endothelial cells for fluid shear stress

Hierck, B. P., Van der Heiden, K., Alkemade, F. E., Van de Pas, S., Van Thienen, J. V., Groenendijk, B. C. W., Bax, W. H., Van der Laarse, A., DeRuiter, M. C., Horrevoets, A. J. G., et al. (2008) · Developmental Dynamics · doi:10.1002/dvdy.21472 · Cited by 187 · see citing works

Specific Phospholipid Oxidation Products Inhibit Ligand Activation of Toll-Like Receptors 4 and 2

Walton, K. A., Cole, A. L., Yeh, M. W., Subbanagounder, G., Krutzik, S. R., Modlin, R. L., Lucas, R. M., Nakai, J., Smart, E. J., Vora, D. K., et al. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000079340.80744.b8 · Cited by 183 · see citing works

Functions of Toll-like receptors: lessons from KO mice

Akira, S., & Takeda, K. (2004) · Comptes Rendus Biologies · doi:10.1016/j.crvi.2004.04.002 · Cited by 179 · see citing works

Infectious Agents Are Not Necessary for Murine Atherogenesis

Wright, S. D., Burton, C., Hernandez, M., Hassing, H., Montenegro, J., Mundt, S., Patel, S., Card, D. J., Hermanowski-Vosatka, A., Bergstrom, J. D., et al. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.191.8.1437 · Cited by 176 · see citing works

Endothelial Responses to Oxidized Lipoproteins Determine Genetic Susceptibility to Atherosclerosis in Mice

Shi, W., Haberland, M. E., Jien, M.-L., Shih, D. M., & Lusis, A. J. (2000) · Circulation · doi:10.1161/01.cir.102.1.75 · Cited by 172 · see citing works

Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse

Paigen, B. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.2.458s · Cited by 150 · see citing works

Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids

Liu, X., Ukai, T., Yumoto, H., Davey, M., Goswami, S., Gibson, F. C., & Genco, C. A. (2007) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2007.03.025 · Cited by 149 · see citing works

Laminar shear stress acts as a switch to regulate divergent functions of NF‐κB in endothelial cells

Partridge, J., Carlsen, H., Enesa, K., Chaudhury, H., Zakkar, M., Luong, L. A., Kinderlerer, A. R., Johns, M., Blomhoff, R., Mason, J. C., et al. (2007) · The FASEB Journal · doi:10.1096/fj.06-8059com · Cited by 142 · see citing works

Hemodynamics in the mouse aortic arch as assessed by MRI, ultrasound, and numerical modeling

Feintuch, A., Ruengsakulrach, P., Lin, A., Zhang, J., Zhou, Y., Bishop, J., Davidson, L., Courtman, D. W., Foster, F. S., Steinman, D. A., et al. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00796.2006 · Cited by 128 · see citing works

RAGE on the Toll Road?

Li, L. (2006) · PubMed · Cited by 127 · see citing works

NATURAL HISTORY AND RISK FACTORS OF ATHEROSCLEROSIS IN CHILDREN AND YOUTH: THE PDAY STUDY

Zieske, A. W., Malcom, G. T., & Strong, J. P. (2002) · Fetal and Pediatric Pathology · doi:10.1080/pdp.21.2.213.237 · Cited by 124 · see citing works

Phosphocholine as a pattern recognition ligand for CD36

Boullier, A., Friedman, P., Harkewicz, R., Hartvigsen, K., Green, S. R., Almazan, F., Dennis, E. A., Steinberg, D. H., Witztum, J. L., & Quehenberger, O. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m400496-jlr200 · Cited by 123 · see citing works

Increased Endothelial Mitogen-Activated Protein Kinase Phosphatase-1 Expression Suppresses Proinflammatory Activation at Sites That Are Resistant to Atherosclerosis

Zakkar, M., Chaudhury, H., Sandvik, G. F., Enesa, K., Luong, L. A., Cuhlmann, S., Mason, J. C., Krams, R., Clark, A. R., Haskard, D. O., et al. (2008) · Circulation Research · doi:10.1161/circresaha.108.183913 · Cited by 116 · see citing works

Conditional signaling by Toll‐like receptor 4

Brunn, G. J., Bungum, M. K., Johnson, G. B., & Platt, J. L. (2005) · The FASEB Journal · doi:10.1096/fj.04-3211fje · Cited by 104 · see citing works

Multiple roles of Toll-like receptor signaling in atherosclerosis

Björkbacka, H. (2006) · Current Opinion in Lipidology · doi:10.1097/01.mol.0000245258.25387.ec · Cited by 95 · see citing works

Toll-Like Receptor-2 Mediates Diet and/or Pathogen Associated Atherosclerosis: Proteomic Findings

Madan, M., & Amar, S. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003204 · Cited by 95 · see citing works

Cellular Physiology of Cholesterol Efflux in Vascular Endothelial Cells

O’Connell, B. J., Denis, M., & Genest, J. J. (2004) · Circulation · doi:10.1161/01.cir.0000146333.20727.2b · Cited by 95 · see citing works

Toll like receptors and viruses

Finberg, R. W., Wang, J. P., & Kurt‐Jones, E. A. (2007) · Reviews in Medical Virology · doi:10.1002/rmv.525 · Cited by 90 · see citing works

Endothelial scavenger receptors

ADACHI, H., & Tsujimoto, M. (2006) · Progress in Lipid Research · doi:10.1016/j.plipres.2006.03.002 · Cited by 87 · see citing works

Adaptation of the endothelium to fluid flow: in vitro analyses of gene expression and in vivo implications

Wasserman, S. M., & Topper, J. N. (2004) · Vascular Medicine · doi:10.1191/1358863x04vm521ra · Cited by 87 · see citing works

A combination of Lox-1 and Nox1 regulates TLR9-mediated foam cell formation

Lee, J., Lim, E., Park, D., Lee, S.-H., Kim, J.-R., & Baek, S. (2008) · Cellular Signalling · doi:10.1016/j.cellsig.2008.08.022 · Cited by 76 · see citing works

Toll-like receptors: another player in the pathogenesis of the anti-phospholipid syndrome

Raschi, E., Borghi, M. O., Grossi, C., Broggini, V., Pierangeli, S. S., & Meroni, P. L. (2008) · Lupus · doi:10.1177/0961203308095140 · Cited by 66 · see citing works

Microorganisms in the aetiology of atherosclerosis

Morré, S. A., Stooker, W., Lagrand, W. K., van den Brule, A. J. C., & Niessen, H. W. M. (2000) · Journal of Clinical Pathology · doi:10.1136/jcp.53.9.647 · Cited by 64 · see citing works

Early Atherosclerotic Plaques in the Aorta Following Cytomegalovirus Infection of Mice

Berencsi, K., Endrész, V., Klurfeld, D. M., Kari, L., Kritchevsky, D., & Gönczöl, É. (1998) · Cell Communication & Adhesion · doi:10.3109/15419069809005597 · Cited by 59 · see citing works

Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12

Osterloh, A., Veit, A., Gessner, A., Fleischer, B., & Breloer, M. (2008) · International Immunology · doi:10.1093/intimm/dxn003 · Cited by 51 · see citing works

Cardiovascular lipid accumulation with Coxsackie B virus infection in mice.

Ilbäck, N. ‐., Mohammed, A., Fohlman, J., & Friman, G. (1990) · Europe PMC (PubMed Central) · Cited by 48 · see citing works

Deciphering the Endothelial Shear Stress Sensor

Poelmann, R. E., der Heiden, K. V., Groot, A. C. G., & Hierck, B. P. (2008) · Circulation · doi:10.1161/circulationaha.107.753889 · Cited by 48 · see citing works

The Roles of Pathogen-Associated Molecular Patterns in Atherosclerosis

Erridge, C. (2008) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2007.12.003 · Cited by 46 · see citing works

Differential expression of Toll-like receptor 2 (TLR2) and responses to TLR2 ligands between human and murine vascular endothelial cells

Chen, S., Wong, M. H., Schulte, D. J., Arditi, M., & Michelsen, K. S. (2007) · Journal of Endotoxin Research · doi:10.1177/0968051907085096 · Cited by 44 · see citing works

Delivery of Chlamydia pneumoniae to the vessel wall aggravates atherosclerosis in LDLr-/- mice

Hauer, A. D., Devos, P., Peterse, N., Cate, H. T., VANBERKEL, T., Stassen, F. R. M., & Kuiper, J. (2005) · Cardiovascular Research · doi:10.1016/j.cardiores.2005.07.011 · Cited by 34 · see citing works

The Inflammatory Hypothesis

Blankenberg, S., & Yusuf, S. (2006) · Circulation · doi:10.1161/circulationaha.106.652081 · Cited by 34 · see citing works

Effects of disturbed flow on endothelial cell function: Pathogenic implications of modified leukocyte recruitment

Matharu, N. M., Rainger, G. E., Vohra, R. K., & Nash, G. B. (2006) · Biorheology · doi:10.1177/0006355x2006043001002 · Cited by 26 · see citing works

Oxidised phospholipid regulation of Toll-like receptor signalling

Erridge, C., & Spickett, C. M. (2007) · Redox Report · doi:10.1179/135100007x162121 · Cited by 17 · see citing works

Differential induction of apoptosis by LPS and taxol in monocytic cells

Li, T., Hu, J., Thomas, J. A., & Li, L. (2004) · Molecular Immunology · doi:10.1016/j.molimm.2004.09.032 · Cited by 14 · see citing works

Atheroma: a new hypothesis.

Caro, C. G., Fitz-Gerald, J. M., & Schroter, R. C. (1971) · BMJ · doi:10.1136/bmj.2.5762.651-c · Cited by 12 · see citing works

Macrophages in the Pathogenesis of Atherosclerosis

Moore, K. J., & Tabas, I. (2011) · Cell · doi:10.1016/j.cell.2011.04.005 · Cited by 2,669 · see citing works

The immune system in atherosclerosis

Hansson, G. K., & Hermansson, A. (2011) · Nature Immunology · doi:10.1038/ni.2001 · Cited by 2,331 · see citing works

Atherosclerosis: current pathogenesis and therapeutic options

Weber, C., & Noels, H. (2011) · Nature Medicine · doi:10.1038/nm.2538 · Cited by 2,203 · see citing works

Immunity and Inflammation in Atherosclerosis

Wolf, D., & Ley, K. F. (2019) · Circulation Research · doi:10.1161/circresaha.118.313591 · Cited by 1,754 · see citing works

Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update

Kyriakis, J. M., & Avruch, J. (2012) · Physiological Reviews · doi:10.1152/physrev.00028.2011 · Cited by 1,476 · see citing works

Macrophage death and defective inflammation resolution in atherosclerosis

Tabas, I. (2010) · Nature Reviews Immunology · doi:10.1038/nri2675 · Cited by 1,120 · see citing works

Inflammation and Lipid Signaling in the Etiology of Insulin Resistance

Glass, C. K., & Olefsky, J. M. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.04.001 · Cited by 942 · see citing works

The role of short-chain fatty acids in the interplay between gut microbiota and diet in cardio-metabolic health

Nogal, A., Valdes, A. M., & Menni, C. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1897212 · Cited by 917 · see citing works

<i>Akkermansia Muciniphila</i> Protects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation in <i>Apoe</i> ^−/− Mice

Li, J., Lin, S., Vanhoutte, P. M., Woo, C. W., & Xu, A. (2016) · Circulation · doi:10.1161/circulationaha.115.019645 · Cited by 775 · see citing works

Immune Effector Mechanisms Implicated in Atherosclerosis: From Mice to Humans

Libby, P., Lichtman, A. H., & Hansson, G. K. (2013) · Immunity · doi:10.1016/j.immuni.2013.06.009 · Cited by 667 · see citing works

Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity

Miller, Y. I., Choi, S.-H., Wiesner, P., Fang, L., Harkewicz, R., Hartvigsen, K., Boullier, A., Gonen, A., Diehl, C. J., Que, X., et al. (2011) · Circulation Research · doi:10.1161/circresaha.110.223875 · Cited by 654 · see citing works

Increased Toll-Like Receptor (TLR) Activation and TLR Ligands in Recently Diagnosed Type 2 Diabetic Subjects

Dasu, M. R., Devaraj, S., Park, S., & Jialal, I. (2010) · Diabetes Care · doi:10.2337/dc09-1799 · Cited by 572 · see citing works

Antibody-independent functions of B cells: a focus on cytokines

Shen, P., & Fillatreau, S. (2015) · Nature Reviews Immunology · doi:10.1038/nri3857 · Cited by 508 · see citing works

Gut Microbiota, Lipopolysaccharides, and Innate Immunity in the Pathogenesis of Obesity and Cardiovascular Risk

Manco, M., Putignani, L., & Bottazzo, G. F. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0030 · Cited by 479 · see citing works

The Gut Microbial Endocrine Organ: Bacterially Derived Signals Driving Cardiometabolic Diseases

Brown, J. M., & Hazen, S. L. (2015) · Annual Review of Medicine · doi:10.1146/annurev-med-060513-093205 · Cited by 438 · see citing works

Vascular smooth muscle cell in atherosclerosis

Chistiakov, D. A., Orekhov, A. N., & Bobryshev, Y. V. (2015) · Acta Physiologica · doi:10.1111/apha.12466 · Cited by 384 · see citing works

Atherosclerosis and Inflammation: Insights from the Theory of General Pathological Processes

Gusev, E., & Sarapultsev, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24097910 · Cited by 336 · see citing works

The Influence of Innate and Adaptive Immune Responses on Atherosclerosis

Witztum, J. L., & Lichtman, A. H. (2013) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-020712-163936 · Cited by 277 · see citing works

Fish Oil Enhances Intestinal Integrity and Inhibits TLR4 and NOD2 Signaling Pathways in Weaned Pigs after LPS Challenge3

Liu, Y., Chen, F., Odle, J., Lin, X., Jacobi, S. K., Zhu, H., Wu, Z., & Hou, Y. (2012) · Journal of Nutrition · doi:10.3945/jn.112.164947 · Cited by 275 · see citing works

Mechanisms That Regulate Macrophage Burden in Atherosclerosis

Randolph, G. J. (2014) · Circulation Research · doi:10.1161/circresaha.114.301174 · Cited by 265 · see citing works

Mechanisms and consequences of efferocytosis in advanced atherosclerosis

Thorp, E., & Tabas, I. (2009) · Journal of Leukocyte Biology · doi:10.1189/jlb.0209115 · Cited by 231 · see citing works

Mechanisms of Immune Complex–Mediated Neutrophil Recruitment and Tissue Injury

Mayadas, T. N., Tsokos, G. C., & Tsuboi, N. (2009) · Circulation · doi:10.1161/circulationaha.108.771170 · Cited by 208 · see citing works

Apolipoprotein E Enhances MicroRNA-146a in Monocytes and Macrophages to Suppress Nuclear Factor-κB–Driven Inflammation and Atherosclerosis

Li, K., Ching, D., Luk, F. S., & Raffaı̈, R. L. (2015) · Circulation Research · doi:10.1161/circresaha.117.305844 · Cited by 210 · see citing works

Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors

Dasu, M. R. K., & Jialal, I. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00490.2010 · Cited by 211 · see citing works

Adaptive (T and B Cells) Immunity and Control by Dendritic Cells in Atherosclerosis

Ait‐Oufella, H., Sage, A. P., Mallat, Z., & Tedgui, A. (2014) · Circulation Research · doi:10.1161/circresaha.114.302761 · Cited by 201 · see citing works

Advances in the design and delivery of peptide subunit vaccines with a focus on Toll-like receptor agonists

Black, M., Trent, A., Tirrell, M., & Olive, C. (2010) · Expert Review of Vaccines · doi:10.1586/erv.09.160 · Cited by 203 · see citing works

Endothelial dysfunction in rheumatic autoimmune diseases

Murdaca, G., Colombo, B. M., Cagnati, P., Gulli, R., Spanò, F. M., & Puppo, F. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2012.05.013 · Cited by 199 · see citing works

Cardiovascular Risk in Fatty Liver Disease: The Liver-Heart Axis—Literature Review

Ismaiel, A., & Dumitrascu, D. L. (2019) · Frontiers in Medicine · doi:10.3389/fmed.2019.00202 · Cited by 193 · see citing works

Lipid Droplets as Immune Modulators in Myeloid Cells

den Brok, M. H., Raaijmakers, T. K., Collado-Camps, E., & Adema, G. J. (2018) · Trends in Immunology · doi:10.1016/j.it.2018.01.012 · Cited by 203 · see citing works

Elevated expression of the toll like receptors 2 and 4 in obese individuals: its significance for obesity-induced inflammation

Ahmad, R., Al‐Mass, A., Atizado, V., Alhubail, A., Al-Ghimlas, F., Alarouj, M., Bennakhi, A., Dermime, S., & Behbehani, K. (2012) · Journal of Inflammation · doi:10.1186/1476-9255-9-48 · Cited by 171 · see citing works

Inflammasomes link vascular disease with neuroinflammation and brain disorders

Lénárt, N., Brough, D., & Dénes, Á. (2016) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x16662043 · Cited by 169 · see citing works

Relation between TLR4/NF‐κB signaling pathway activation by 27‐hydroxycholesterol and 4‐hydroxynonenal, and atherosclerotic plaque instability

Gargiulo, S., Gamba, P., Testa, G., Rossin, D., Biasi, F., Poli, G., & Leonarduzzi, G. (2015) · Aging Cell · doi:10.1111/acel.12322 · Cited by 162 · see citing works

New paradigms in inflammatory signaling in vascular endothelial cells

Xiao, L., Liu, Y., & Wang, N. (2013) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00182.2013 · Cited by 162 · see citing works

The role of Akkermansia muciniphila in obesity, diabetes and atherosclerosis

Hasani, A., Ebrahimzadeh, S., Hemmati, F., Khabbaz, A., Hasani, A., & Gholizadeh, P. (2021) · Journal of Medical Microbiology · doi:10.1099/jmm.0.001435 · Cited by 152 · see citing works

Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques

Fotakis, P., Kothari, V. M., Thomas, D. G., Westerterp, M., Molusky, M. M., Altin, E. S., Abramowicz, S., Wang, N., He, Y., Heinecke, J. W., et al. (2019) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.119.313253 · Cited by 148 · see citing works

Role of vascular smooth muscle cell in the inflammation of atherosclerosis

Lim, S., & Park, S. (2014) · BMB Reports · doi:10.5483/bmbrep.2014.47.1.285 · Cited by 147 · see citing works

A global perspective on the crosstalk between saturated fatty acids and Toll-like receptor 4 in the etiology of inflammation and insulin resistance

Ли, Б., Leung, J. C. K., Chan, L. Y. Y., Yiu, W. H., & Tang, S. C. W. (2019) · Progress in Lipid Research · doi:10.1016/j.plipres.2019.101020 · Cited by 146 · see citing works

SARS-CoV-2 Mediated Endothelial Dysfunction: The Potential Role of Chronic Oxidative Stress

Chang, R. P., Mamun, A., Dominic, A., & Le, N. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2020.605908 · Cited by 131 · see citing works

Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markers

López‐Mejías, R., Castañeda, S., González‐Juanatey, C., Corrales, A., Ferraz‐Amaro, I., Genre, F., Remuzgo‐Martínez, S., Rodríguez‐Rodríguez, L., Blanco, R., Llorca, J., et al. (2016) · Autoimmunity Reviews · doi:10.1016/j.autrev.2016.07.026 · Cited by 134 · see citing works

Chondrocyte innate immune myeloid differentiation factor 88–dependent signaling drives procatabolic effects of the endogenous toll‐like receptor 2/toll‐like receptor 4 ligands low molecular weight hyaluronan and high mobility group box chromosomal protein 1 in mice

Liu‐Bryan, R., & Terkeltaub, R. A. (2010) · Arthritis & Rheumatism · doi:10.1002/art.27475 · Cited by 133 · see citing works

Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B

Woo, C. W., Kutzler, L., Kimball, S. R., & Tabas, I. A. (2012) · Nature Cell Biology · doi:10.1038/ncb2408 · Cited by 129 · see citing works

Characterization of Sparstolonin B, a Chinese Herb-derived Compound, as a Selective Toll-like Receptor Antagonist with Potent Anti-inflammatory Properties

Liang, Q., Wu, Q., Jiang, J., Duan, J., Wang, C., Smith, M. D., Lu, H. S., Wang, Q., Nagarkatti, P. S., & Fan, D. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.227934 · Cited by 124 · see citing works

High-Fat Diet Consumption Induces Microbiota Dysbiosis and Intestinal Inflammation in Zebrafish

Arias-Jayo, N., Abecia, L., Alonso‐Sáez, L., Ramirez‐Garcia, A., Rodriguez, A., & Pardo, M. Á. (2018) · Microbial Ecology · doi:10.1007/s00248-018-1198-9 · Cited by 115 · see citing works

Caspase-1–mediated pathway promotes generation of thromboinflammatory microparticles

Rothmeier, A. S., Marchese, P., Petrich, B. G., Furlan-Freguia, C., Ginsberg, M. H., Ruggeri, Z. M., & Ruf, W. (2015) · Journal of Clinical Investigation · doi:10.1172/jci79329 · Cited by 111 · see citing works

The role of macrophages and dendritic cells in the clearance of apoptotic cells in advanced atherosclerosis

Thorp, E., Subramanian, M., & Tabas, I. (2011) · European Journal of Immunology · doi:10.1002/eji.201141719 · Cited by 107 · see citing works

Toll-Like Receptor 7 Protects From Atherosclerosis by Constraining “Inflammatory” Macrophage Activation

Salagianni, M. L., Galani, I. E., Lundberg, A. M., Davos, C. H., Varela, A., Gavriil, A., Lyytikäinen, L., Lehtimäki, T. J., Sigala, F., Folkersen, L., et al. (2012) · Circulation · doi:10.1161/circulationaha.111.067678 · Cited by 105 · see citing works

Functions of omega-3 fatty acids and FFA4 (GPR120) in macrophages

Im, D. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.03.094 · Cited by 104 · see citing works

Effects of PCSK9 Targeting: Alleviating Oxidation, Inflammation, and Atherosclerosis

Punch, E., Klein, J., Diaba‐Nuhoho, P., Morawietz, H., & Garelnabi, M. (2022) · Journal of the American Heart Association · doi:10.1161/jaha.121.023328 · Cited by 101 · see citing works

Natural killer T cells in atherosclerosis

Getz, G. S., & Reardon, C. A. (2017) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2017.2 · Cited by 100 · see citing works

Obesity and the gut microbiome: Striving for causality

Harley, I. T. W., & Karp, C. L. (2012) · Molecular Metabolism · doi:10.1016/j.molmet.2012.07.002 · Cited by 96 · see citing works

Obesity: An Immunometabolic Perspective

Ray, I., Mahata, S. K., & De, R. K. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00157 · Cited by 100 · see citing works

Regulatory T Cells and Atherosclerosis

Lopez‐Pastrana, J. (2013) · Journal of Clinical & Experimental Cardiology · doi:10.4172/2155-9880.s12-002 · Cited by 97 · see citing works

Treatment With Methotrexate Inhibits Atherogenesis in Cholesterol-Fed Rabbits

Bulgarelli, A., Dias, A. A. M., Caramelli, B., & Maranhão, R. C. (2011) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0b013e318241c385 · Cited by 95 · see citing works

Pathophysiology of cardiovascular disease in diabetes mellitus

Rodriguez‐Araujo, G., & Hironori Nakagami, A. (2018) · Cardiovascular Endocrinology & Metabolism · doi:10.1097/xce.0000000000000141 · Cited by 95 · see citing works

Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease

Rohde, D., Vandoorne, K., Lee, I., Grune, J., Zhang, S., McAlpine, C. S., Schloss, M. J., Nayar, R., Courties, G., Frodermann, V., et al. (2021) · Nature Cardiovascular Research · doi:10.1038/s44161-021-00002-8 · Cited by 94 · see citing works

Immunometabolism and immune response regulate macrophage function in atherosclerosis

Xue, S., Su, Z., & Liu, D. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101993 · Cited by 94 · see citing works

Oxidation-specific epitopes and immunological responses: Translational biotheranostic implications for atherosclerosis

Leibundgut, G., Witztum, J. L., & Tsimikas, S. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.02.005 · Cited by 88 · see citing works

Toll-like Receptor Signaling Pathways in Cardiovascular Diseases: Challenges and Opportunities

Bijani, F. M., Vallejo, J. G., & Rezaei, N. (2012) · International Reviews of Immunology · doi:10.3109/08830185.2012.706761 · Cited by 88 · see citing works

TLR2 Promotes Vascular Smooth Muscle Cell Chondrogenic Differentiation and Consequent Calcification via the Concerted Actions of Osteoprotegerin Suppression and IL-6–Mediated RANKL Induction

Lee, G.-L., Yeh, C.-C., Wu, J.-Y., Lin, H., Wang, Y., Kuo, Y.-Y., Hsieh, Y.-T., Hsu, Y., & Kuo, C.-C. (2019) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.118.311874 · Cited by 84 · see citing works

Toll-Like Receptors (TLRs): The Role in Tumor Progression

Shcheblyakov, D. V., Logunov, D. Y., Ильдарович, Т. А., Шмаров, М. М., Naroditsky, B. S., & Ginzburg, A. (2010) · Acta Naturae · doi:10.32607/20758251-2010-2-3-21-29 · Cited by 82 · see citing works

Cardiolipotoxicity, Inflammation, and Arrhythmias: Role for Interleukin-6 Molecular Mechanisms

Alì, A., Boutjdir, M., & Aromolaran, A. S. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2018.01866 · Cited by 82 · see citing works

Cross-talk between macrophages and smooth muscle cells impairs collagen and metalloprotease synthesis and promotes angiogenesis

Butoi, E. D., Gan, A., Tucureanu, M. M., Stan, D. L., Macarie, R. D., Constantinescu, C., Călin, M., Simionescu, M., & Mânduțeanu, I. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2016.04.001 · Cited by 80 · see citing works

Sphingosine 1-phosphate induced anti-atherogenic and atheroprotective M2 macrophage polarization through IL-4

Park, S.-J., Lee, K., Kang, S., Lee, J., Sato, K., Chung, H. Y., Okajima, F., & Im, D. (2014) · Cellular Signalling · doi:10.1016/j.cellsig.2014.07.009 · Cited by 79 · see citing works

Causes and consequences of low grade endotoxemia and inflammatory diseases

Glaros, T. (2012) · Frontiers in Bioscience-Scholar · doi:10.2741/s405 · Cited by 78 · see citing works

Autoimmune heart disease: role of sex hormones and autoantibodies in disease pathogenesis

Fairweather, D., Petri, M., Coronado, M. J., & Cooperr, L. T. (2012) · Expert Review of Clinical Immunology · doi:10.1586/eci.12.10 · Cited by 74 · see citing works

Toll-like receptors mediating vascular malfunction: Lessons from receptor subtypes

Wang, Y., Song, E., Bai, B., & Vanhoutte, P. M. (2015) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2015.12.005 · Cited by 75 · see citing works

TLR2 Plays a Key Role in Platelet Hyperreactivity and Accelerated Thrombosis Associated With Hyperlipidemia

Biswas, S., Zimman, A., Gao, D., Byzova, T. V., & Podrez, E. A. (2017) · Circulation Research · doi:10.1161/circresaha.117.311069 · Cited by 75 · see citing works

Lipopolysaccharide-binding protein (LBP) is associated with total and cardiovascular mortality in individuals with or without stable coronary artery disease – Results from the Ludwigshafen Risk and Cardiovascular Health Study (LURIC)

Lepper, P. M., Kleber, M. E., Grammer, T. B., Hoffmann, K., Dietz, S., Winkelmann, B. R., Boehm, B. O., & März, W. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.06.001 · Cited by 74 · see citing works

Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus?

Juwono, J., & Martinus, R. D. (2016) · Journal of Diabetes Research · doi:10.1155/2016/8017571 · Cited by 71 · see citing works

The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice

Kiouptsi, K., Jäckel, S., Pontarollo, G., Grill, A., Kuijpers, M. J. E., Wilms, E., Weber, C., Sommer, F., Nagy, M., Neideck, C., et al. (2019) · mBio · doi:10.1128/mbio.02298-19 · Cited by 70 · see citing works

Endotoxin, Toll-like Receptor-4, and Atherosclerotic Heart Disease

Bowman, J. D., Surani, S., & Horseman, M. A. (2016) · Current Cardiology Reviews · doi:10.2174/1573403x12666160901145313 · Cited by 67 · see citing works

Lipopolysaccharide and Sphingosine-1-Phosphate Cooperate To Induce Inflammatory Molecules and Leukocyte Adhesion in Endothelial Cells

Fernández‐Pisonero, I., Dueñas, A. I., Barreiro, O., Montero, O., Sánchez‐Madrid, F., & García‐Rodríguez, C. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1201309 · Cited by 67 · see citing works

Macrophage-Derived Myeloid Differentiation Protein 2 Plays an Essential Role in ox-LDL-Induced Inflammation and Atherosclerosis

Chen, T., Huang, W., Qian, J., Luo, W., Shan, P., Cai, Y., Lin, K., Wu, G., & Liang, G. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2020.102706 · Cited by 66 · see citing works

A Gene Expression Signature That Classifies Human Atherosclerotic Plaque by Relative Inflammation Status

Puig, Ó., Yuan, J., Stepaniants, S. B., Zieba, R., Zycband, E., Morris, M. D., Coulter, S., Yu, X., Menke, J. G., Woods, J., et al. (2011) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.111.960773 · Cited by 64 · see citing works

Altered sciatic nerve fiber morphology and endoneural microvessels in mouse models relevant for obesity, peripheral diabetic polyneuropathy, and the metabolic syndrome

Nowicki, M., Kosacka, J., Serke, H., Blüher, M., & Spanel‐Borowski, K. (2011) · Journal of Neuroscience Research · doi:10.1002/jnr.22728 · Cited by 62 · see citing works

TLR 2 Induces Vascular Smooth Muscle Cell Migration Through cAMP Response Element−Binding Protein−Mediated Interleukin-6 Production

Lee, G.-L., Chang, Y.-W., Wu, J.-Y., Wu, M., Wu, K. K., Yet, S., & Kuo, C.-C. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.300302 · Cited by 63 · see citing works

Matricryptic sites control tissue injury responses in the cardiovascular system: Relationships to pattern recognition receptor regulated events

Davis, G. E. (2009) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2009.09.002 · Cited by 62 · see citing works

HIV, Inflammation, and Calcium in Atherosclerosis

Shrestha, S., Irvin, M. R., Grünfeld, C., & Arnett, D. K. (2013) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.113.302191 · Cited by 61 · see citing works

The extrinsic RNA-sensing pathway for adjuvant immunotherapy of cancer

Seya, T., & Matsumoto, M. (2009) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-008-0652-9 · Cited by 59 · see citing works

Serum Lipopolysaccharide‐Binding Protein Levels and the Incidence of Cardiovascular Disease in a General Japanese Population: The Hisayama Study

Asada, M., Oishi, E., Sakata, S., Hata, J., Yoshida, D., Honda, T., Furuta, Y., Shibata, M., Suzuki, K., Watanabe, H., et al. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.119.013628 · Cited by 60 · see citing works

The Metabolic Role of Gut Microbiota in the Development of Nonalcoholic Fatty Liver Disease and Cardiovascular Disease

Sanduzzi‐Zamparelli, M., Compare, D., Coccoli, P., Rocco, A., Nardone, O. M., Marrone, G., Gasbarrini, A., Grieco, A., Nardone, G., & Miele, L. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17081225 · Cited by 59 · see citing works

An Innate Immunity Signaling Process Suppresses Macrophage ABCA1 Expression through IRAK-1-Mediated Downregulation of Retinoic Acid Receptor α and NFATc2

Maitra, U., Parks, J. S., & Li, L. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00541-09 · Cited by 59 · see citing works

FFA4 (GPR120) as a fatty acid sensor involved in appetite control, insulin sensitivity and inflammation regulation

Im, D. (2017) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2017.09.001 · Cited by 59 · see citing works

Psychological factors and DNA methylation of genes related to immune/inflammatory system markers: the VA Normative Aging Study

Kim, D. J., Kubzansky, L. D., Baccarelli, A., Sparrow, D., Spiro, A., Tarantini, L., Cantone, L., Vokonas, P., & Schwartz, J. D. (2016) · BMJ Open · doi:10.1136/bmjopen-2015-009790 · Cited by 58 · see citing works

Asparagine improves intestinal integrity, inhibits TLR4 and NOD signaling, and differently regulates p38 and ERK1/2 signaling in weanling piglets after LPS challenge

Chen, S., Liu, Y., Wang, X., Wang, H., Li, S., Shi, H., Zhu, H., Zhang, J., Pi, D., Hu, C. A., et al. (2016) · Innate Immunity · doi:10.1177/1753425916664124 · Cited by 53 · see citing works

Interaction of NADPH oxidase 1 with Toll-like receptor 2 induces migration of smooth muscle cells

Lee, J. H., Joo, J. H., Kim, J., Lim, H. J., Kim, S. A., Curtiss, L. K., Seong, J. K., Cui, W., Yabe‐Nishimura, C., & Bae, Y. S. (2013) · Cardiovascular Research · doi:10.1093/cvr/cvt107 · Cited by 51 · see citing works

Patterns of Toll-Like Receptor Expressions and Inflammatory Cytokine Levels and Their Implications in the Progress of Insulin Resistance and Diabetic Nephropathy in Type 2 Diabetic Patients

Aly, R. H., Ahmed, A. E., Hozayen, W. G., Rabea, A. M., Ali, T. M., Askary, A. E., & Ahmed, O. M. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.609223 · Cited by 54 · see citing works

Oral Bacterial Signatures in Cerebral Thrombi of Patients With Acute Ischemic Stroke Treated With Thrombectomy

Patrakka, O., Pienimäki, J., Tuomisto, S., Ollikainen, J., Lehtimäki, T. J., Karhunen, P. J., & Martiskainen, M. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.119.012330 · Cited by 51 · see citing works

Viral and bacterial patterns induce TLR-mediated sustained inflammation and calcification in aortic valve interstitial cells

López, J., Fernández‐Pisonero, I., Dueñas, A. I., Maeso, P. A., Román, J. A. S., Crespo, M. S., & García‐Rodríguez, C. (2011) · International Journal of Cardiology · doi:10.1016/j.ijcard.2010.12.089 · Cited by 50 · see citing works

Sphingomyelin synthase 2 (SMS2) deficiency attenuates LPS-induced lung injury

Gowda, S., Yeang, C., Wadgaonkar, S., Anjum, F., Grinkina, N., Cutaia, M. V., Jiang, X.-C., & Wadgaonkar, R. (2010) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00208.2010 · Cited by 49 · see citing works

TLR4-Activated MAPK-IL-6 Axis Regulates Vascular Smooth Muscle Cell Function

Lee, G.-L., Wu, J.-Y., Tsai, C., Lin, C.-Y., Tsai, Y., Lin, C., Wang, Y., Yet, S., Hsu, Y., & Kuo, C.-C. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17091394 · Cited by 49 · see citing works

Saturated Fatty Acid Palmitate Aggravates Neointima Formation by Promoting Smooth Muscle Phenotypic Modulation

Shen, H., Eguchi, K., Kono, N., Fujiu, K., Matsumoto, S., Shibata, M., Tanaka, Y., Komuro, I., Arai, H., Nagai, R., et al. (2013) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.113.302099 · Cited by 47 · see citing works

A review of the interaction between diet composition and gut microbiota and its impact on associated disease

Liu, Z., Liu, M., Meng, J., Wang, L., & Chen, M. (2023) · Journal of Future Foods · doi:10.1016/j.jfutfo.2023.07.004 · Cited by 45 · see citing works

Toll-like receptor 2, hyaluronan, and neutrophils play a key role in plaque erosion: the OPTICO–ACS study

Meteva, D., Vinci, R., Seppelt, C., Abdelwahed, Y. S., Pedicino, D., Nelles, G., Skurk, C., Haghikia, A., Rauch, U., Gerhardt, T., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad379 · Cited by 44 · see citing works

Deposition and hydrolysis of serine dipeptide lipids of Bacteroidetes bacteria in human arteries: relationship to atherosclerosis

Nemati, R., Dietz, C. J., Anstadt, E. J., Cervantes, J., Liu, Y., Dewhirst, F. E., Clark, R. B., Finegold, S. M., Gallagher, J. J., Smith, M. B., et al. (2017) · Journal of Lipid Research · doi:10.1194/jlr.m077792 · Cited by 44 · see citing works

Glycine Relieves Intestinal Injury by Maintaining mTOR Signaling and Suppressing AMPK, TLR4, and NOD Signaling in Weaned Piglets after Lipopolysaccharide Challenge

Xu, X. L., Wang, X., Wu, H., Zhu, H., Liu, C., Hou, Y., Dai, B., Liu, X., & Liu, Y. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19071980 · Cited by 43 · see citing works

Flagellin-induced NADPH oxidase 4 activation is involved in atherosclerosis

Kim, J., Seo, M., Kim, S. K., & Bae, Y. S. (2016) · Scientific Reports · doi:10.1038/srep25437 · Cited by 42 · see citing works

Immunität und Entzündung bei Arteriosklerose

Wolf, D., & Ley, K. F. (2019) · Herz · doi:10.1007/s00059-019-4790-y · Cited by 41 · see citing works

The significance of toll-like receptors in human diseases

Vega, M. T. M., & de‐Andrés‐Martín, A. (2009) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2009.04.004 · Cited by 41 · see citing works

Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

Mullick, A. E., Soldau, K., Kiosses, W. B., Bell, T. A., Tobias, P. S., & Curtiss, L. K. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20071096 · Cited by 223 · see citing works

The Toll of Toll-Like Receptors, Especially Toll-Like Receptor 2, on Murine Atherosclerosis

Curtiss, L. K., & Tobias, P. S. (2007) · Current Drug Targets · doi:10.2174/138945007783220605 · Cited by 36 · see citing works

The Roles of Toll-Like Receptors in Atherosclerosis

Erridge, C. (2009) · Journal of Innate Immunity · doi:10.1159/000191413 · Cited by 59 · see citing works

2009 George L. Duff Memorial Lecture—The Toll of Toll-Like Receptors on Atherosclerosis

Curtiss, L. K. (2009) · Circulation · doi:10.1161/circ.120.suppl_18.a17-a

The Expression and Functions of Toll-Like Receptors in Atherosclerosis

Cole, J. E., Georgiou, E. X., & Monaco, C. G. (2010) · Mediators of Inflammation · doi:10.1155/2010/393946 · Cited by 176 · see citing works