Brain‐Derived Neurotrophic Factor in Neuronal Survival and Behavior‐Related Plasticity

Neurotrophins: Roles in Neuronal Development and Function

Huang, E. J., & Reichardt, L. F. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.677 · Cited by 4,394 · see citing works

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

Egan, M. F., Kojima, M., Callicott, J. H., Goldberg, T. E., Kolachana, B. S., Bertolino, A., Zaitsev, E., Gold, B., Goldman, D., Dean, M., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00035-7 · Cited by 3,888 · see citing works

The Role Of Glutamate Neurotoxicity In Hypoxic-Ischemic Neuronal Death

Choi, D. W., & Rothman, S. M. (1990) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.13.030190.001131 · Cited by 2,210 · see citing works

Neurotrophin-regulated signalling pathways

Reichardt, L. F. (2006) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2006.1894 · Cited by 2,195 · see citing works

A molecular and cellular theory of depression

Duman, R. S. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830190015002 · Cited by 2,129 · see citing works

Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

Berton, O., McClung, C. A., DiLeone, R. J., Krishnan, V., Renthal, W., Russo, S. J., Graham, D., Tsankova, N. M., Bolanos, C. A., Rios, M., et al. (2006) · Science · doi:10.1126/science.1120972 · Cited by 2,129 · see citing works

Regulation of Cell Survival by Secreted Proneurotrophins

Lee, R., Kermani, P., Teng, K. K., & Hempstead, B. L. (2001) · Science · doi:10.1126/science.1065057 · Cited by 1,670 · see citing works

The yin and yang of neurotrophin action

Lu, B., Pang, P. T., & Woo, N. H. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1726 · Cited by 1,356 · see citing works

Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior

Chen, Z.-Y., Jing, D., Bath, K. G., Ieraci, A., Khan, T., Siao, C.-J., Herrera, D. G., Toth, M., Yang, C., McEwen, B. S., et al. (2006) · Science · doi:10.1126/science.1129663 · Cited by 1,340 · see citing works

Nerve Growth Factor Signaling, Neuroprotection, and Neural Repair

Sofroniew, M. V., Howe, C. L., & Mobley, W. C. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.1217 · Cited by 1,284 · see citing works

Increased hippocampal bdnf immunoreactivity in subjects treated with antidepressant medication

Chen, B., Dowlatshahi, D., MacQueen, G. M., Wang, J.-F., & Young, L. T. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01083-6 · Cited by 1,164 · see citing works

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

Ernfors, P., Lee, K.-F., & Jaenisch, R. (1994) · Nature · doi:10.1038/368147a0 · Cited by 1,067 · see citing works

Brain-Derived Neurotrophic Factor val ⁶⁶ met Polymorphism Affects Human Memory-Related Hippocampal Activity and Predicts Memory Performance

Hariri, A. R., Goldberg, T. E., Mattay, V. S., Kolachana, B. S., Callicott, J. H., Egan, M. F., & Weinberger, D. R. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-17-06690.2003 · Cited by 1,045 · see citing works

A Requirement for Local Protein Synthesis in Neurotrophin-Induced Hippocampal Synaptic Plasticity

Kang, H., & Schuman, E. (1996) · Science · doi:10.1126/science.273.5280.1402 · Cited by 1,010 · see citing works

The brain-derived neurotrophic factor Val66Met polymorphism and variation in human cortical morphology

Pezawas, L., Verchinski, B. A., Mattay, V. S., Callicott, J. H., Kolachana, B. S., Straub, R. E., Egan, M. F., Meyer-Lindenberg, A., & Weinberger, D. R. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.2680-04.2004 · Cited by 890 · see citing works

Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities

Lyons, W. E., Mamounas, L. A., Ricaurte, G. A., Coppola, V., Reid, S. W., Bora, S. H., Wihler, C., Koliatsos, V. E., & Tessarollo, L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.26.15239 · Cited by 862 · see citing works

p75 and Trk: A two-receptor system

Chao, M. V., & Hempstead, B. L. (1995) · Trends in Neurosciences · doi:10.1016/0166-2236(95)93922-k · Cited by 857 · see citing works

Activation of p75NTR by proBDNF facilitates hippocampal long-term depression

Woo, N. H., Teng, H. K., Siao, C.-J., Chiaruttini, C., Pang, P. T., Milner, T. A., Hempstead, B. L., & Lu, B. (2005) · Nature Neuroscience · doi:10.1038/nn1510 · Cited by 815 · see citing works

Brain-Derived Neurotrophic Factor Induces Long-Term Potentiation in Intact Adult Hippocampus: Requirement for ERK Activation Coupled to CREB and Upregulation of<i>Arc</i>Synthesis

Ying, S.-W., Futter, M., Rosenblum, K., Webber, M. J., Hunt, S. P., Bliss, T. V. P., & Bramham, C. R. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-05-01532.2002 · Cited by 784 · see citing works

Conditional Deletion Of Brain-Derived Neurotrophic Factor in the Postnatal Brain Leads to Obesity and Hyperactivity

Rios, M., Fan, G., Fekete, C., Kelly, J., Bates, B., Kuehn, R., Lechan, R. M., & Jaenisch, R. (2001) · Molecular Endocrinology · doi:10.1210/mend.15.10.0706 · Cited by 781 · see citing works

Two components of long-term potentiation induced by different patterns of afferent activation

Grover, L. M., & Teyler, T. J. (1990) · Nature · doi:10.1038/347477a0 · Cited by 708 · see citing works

NF-κB functions in synaptic signaling and behavior

Meffert, M. K., Chang, J. M., Wiltgen, B. J., Fanselow, M. S., & Baltimore, D. (2003) · Nature Neuroscience · doi:10.1038/nn1110 · Cited by 690 · see citing works

Essential role of brain-derived neurotrophic factor in adult hippocampal function

Monteggia, L. M., Barrot, M., Powell, C. M., Berton, O., Galanis, V., Gemelli, T., Meuth, S., Nagy, A., Greene, R. W., & Nestler, E. J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402141101 · Cited by 685 · see citing works

Bidirectional Activity-Dependent Morphological Plasticity in Hippocampal Neurons

Nägerl, U. V., Eberhorn, N., Cambridge, S. B., & Bonhoeffer, T. (2004) · Neuron · doi:10.1016/j.neuron.2004.11.016 · Cited by 602 · see citing works

Translational Regulatory Mechanisms in Persistent Forms of Synaptic Plasticity

Kelleher, R. J., Govindarajan, A., & Tonegawa, S. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.013 · Cited by 592 · see citing works

Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression

Manji, H. K., Quiroz, J. A., Sporn, J., Payne, J. L., Denicoff, K. D., Gray, N. A., Zarate, C. A., & Charney, D. S. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00117-3 · Cited by 499 · see citing works

Memories of NMDA receptors and LTP

Collingridge, G. L., & Bliss, T. V. P. (1995) · Trends in Neurosciences · doi:10.1016/0166-2236(95)80016-u · Cited by 493 · see citing works

Naturally Occurring Truncated trkB Receptors Have Dominant Inhibitory Effects on Brain-Derived Neurotrophic Factor Signaling

Eide, F. F., Vining, E. R., Eide, B. L., Zang, K., Wang, X., & Reichardt, L. F. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-10-03123.1996 · Cited by 473 · see citing works

BDNF Val66Met Allele Is Associated with Reduced Hippocampal Volume in Healthy Subjects

Bueller, J. A., Aftab, M., Sen, S., Gomez‐Hassan, D. M., Burmeister, M., & Zubieta, J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.09.022 · Cited by 458 · see citing works

Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression

Eisch, A. J., Bolaños, C. A., de Wit, J., Simonak, R. D., Pudiak, C. M., Barrot, M., Verhaagen, J., & Nestler, E. J. (2003) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.08.003 · Cited by 420 · see citing works

Brain-derived neurotrophic factor Val66met polymorphism and volume of the hippocampal formation

Szeszko, P. R., Lipsky, R. H., Mentschel, C., Robinson, D. G., Gunduz‐Bruce, H., Sevy, S. M., Ashtari, M., Napolitano, B. A., Bilder, R. M., Kane, J. M., et al. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001656 · Cited by 373 · see citing works

Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus

Bashir, Z. I., Alford, S. T., Davies, S. N., Randall, A. D., & Collingridge, G. L. (1991) · Nature · doi:10.1038/349156a0 · Cited by 370 · see citing works

Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases

Seidah, N. G., Benjannet, S., Pareek, S., Chrétien, M., & Murphy, R. A. (1996) · FEBS Letters · doi:10.1016/0014-5793(95)01520-5 · Cited by 364 · see citing works

Truncated TrkB-T1 mediates neurotrophin-evoked calcium signalling in glia cells

Rose, C. R., Blum, R., Pichler, B., Lepier, A., Kafitz, K. W., & Konnerth, A. (2003) · Nature · doi:10.1038/nature01983 · Cited by 356 · see citing works

Signaling from synapse to nucleus: the logic behind the mechanisms

Deisseroth, K. A., Mermelstein, P. G., Xia, H., & Tsien, R. W. (2003) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(03)00076-x · Cited by 350 · see citing works

A BDNF Coding Variant is Associated with the NEO Personality Inventory Domain Neuroticism, a Risk Factor for Depression

Sen, S., Nesse, R. M., Stoltenberg, S. F., Li, S., Gleiberman, L., Chakravarti, A., Weder, A. B., & Burmeister, M. (2002) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300053 · Cited by 331 · see citing works

Regulation of ERK ( Extracellular Signal Regulated Kinase), Part of the Neurotrophin Signal Transduction Cascade, in the Rat Mesolimbic Dopamine System by Chronic Exposure to Morphine or Cocaine

Berhow, M. T., Hiroi, N., & Nestler, E. J. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-15-04707.1996 · Cited by 323 · see citing works

Regulation of the NMDA Receptor Complex and Trafficking by Activity-Dependent Phosphorylation of the NR2B Subunit PDZ Ligand

Chung, H. J., Huang, Y., Lau, L., & Huganir, R. L. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0546-04.2004 · Cited by 315 · see citing works

Metabotropic Glutamate Receptor Subtypes as Targets for Neuroprotective Drugs

Bruno, V., Battaglia, G., Copani, A., D’Onofrio, M., Iorio, P. D., Blasi, A. D., Melchiorri, D., Flor, P. J., & Nicoletti, F. (2001) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200109000-00001 · Cited by 308 · see citing works

Brain-Derived Neurotrophic Factor Triggers Transcription-Dependent, Late Phase Long-Term PotentiationIn Vivo

Messaoudi, E., Ying, S., Kanhema, T., Croll, S. D., & Bramham, C. R. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-17-07453.2002 · Cited by 297 · see citing works

Pro-Region of Neurotrophins

Lu, B. (2003) · Neuron · doi:10.1016/s0896-6273(03)00538-5 · Cited by 267 · see citing works

Transactivation of Trk Neurotrophin Receptors by G-Protein-Coupled Receptor Ligands Occurs on Intracellular Membranes

Rajagopal, R., Chen, Z.-Y., Lee, F. S., & Chao, M. V. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0010-04.2004 · Cited by 258 · see citing works

Polysubstance Abuse–Vulnerability Genes: Genome Scans for Association, Using 1,004 Subjects and 1,494 Single-Nucleotide Polymorphisms

Uhl, G. R., Liu, Q., Walther, D. M., Hess, J., & Naiman, D. Q. (2001) · The American Journal of Human Genetics · doi:10.1086/324467 · Cited by 251 · see citing works

BDNF variation and mood disorders, a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects

Jiang, X., Xu, K., Hoberman, J., Tian, F., Marko, A. J., Waheed, J. F., Harris, C. R., Marini, A. M., Enoch, M.-A., & Lipsky, R. H. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300703 · Cited by 244 · see citing works

RACK1 and Brain-Derived Neurotrophic Factor: A Homeostatic Pathway That Regulates Alcohol Addiction

McGough, N. N. H., He, D., Logrip, M. L., Jeanblanc, J., Phamluong, K., Luong, K., Kharazia, V., Janak, P. H., & Dorit Ron, A. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3714-04.2004 · Cited by 241 · see citing works

Signal Transduction Mediated by the Truncated trkB Receptor Isoforms, trkB.T1 and trkB.T2

Baxter, G. T., Radeke, M. J., Kuo, R. C., Makrides, V., Hinkle, B., Hoang, R., Medina-Selby, A., Coit, D., Valenzuela, P., & Feinstein, S. C. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-08-02683.1997 · Cited by 223 · see citing works

Regulation of CBP-Mediated Transcription by Neuronal Calcium Signaling

Hu, S., Chrivia, J. C., & Ghosh, A. (1999) · Neuron · doi:10.1016/s0896-6273(00)80738-2 · Cited by 222 · see citing works

Activity-dependent Release of Brain-derived Neurotrophic Factor Underlies the Neuroprotective Effect of N-Methyl-d-aspartate

Marini, A. M., Rabin, S. J., Lipsky, R. H., & Mocchetti, I. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.45.29394 · Cited by 201 · see citing works

Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type

Ribasés, M., Gratacòs, M., Armengol, L., de Cid, R., Badía, A., Jiménez, L., Solano, R., Vallejo, J., Fernández, F., & Estivill, X. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001281 · Cited by 200 · see citing works

Analysis of the Human TrkB Gene Genomic Organization Reveals Novel TrkB Isoforms, Unusual Gene Length, and Splicing Mechanism

Stoilov, P., Ċastrén, E., & Stamm, S. (2002) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.6301 · Cited by 191 · see citing works

Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection

Nicoletti, F., Bruno, V., Catania, M. V., Battaglia, G., Copani, A., Barbagallo, G. M. V., Ceña, V., Sánchez‐Prieto, J., Spano, P., & Pizzi, M. (1999) · Neuropharmacology · doi:10.1016/s0028-3908(99)00102-1 · Cited by 169 · see citing works

Mice with reduced brain-derived neurotrophic factor expression show decreased choline acetyltransferase activity, but regular brain monoamine levels and unaltered emotional behavior

Chourbaji, S., Hellweg, R., Brandis, D., Zörner, B., Zacher, C., Lang, U. E., Henn, F. A., Hörtnagl, H., & Gass, P. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2003.11.002 · Cited by 165 · see citing works

Enhancement of Synaptic Plasticity through Chronically Reduced Ca2+ Flux during Uncorrelated Activity

Slutsky, I., Sadeghpour, S., Li, B., & Liu, G. (2004) · Neuron · doi:10.1016/j.neuron.2004.11.013 · Cited by 151 · see citing works

The Activation of Metabotropic Glutamate Receptors Protects Nerve Cells from Oxidative Stress

Sagara, Y., & Schubert, D. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-17-06662.1998 · Cited by 148 · see citing works

A splice variant of the neurotrophin receptor trkB with increased specificity for brain‐derived neurotrophic factor.

Strohmaier, C., Carter, B. D., Urfer, R., Barde, Y., & Dechant, G. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00698.x · Cited by 138 · see citing works

Truncated trkB.T1 Is Dominant Negative Inhibitor of trkB.TK+-Mediated Cell Survival

Haapasalo, A., Koponen, E., Hoppe, E., Wong, G., & Ċastrén, E. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.4296 · Cited by 126 · see citing works

In Vivo Restoration of Physiological Levels of Truncated TrkB.T1 Receptor Rescues Neuronal Cell Death in a Trisomic Mouse Model

Dorsey, S. G., Renn, C. L., Carim‐Todd, L., Barrick, C. A., Bambrick, L. L., Krueger, B. K., Ward, C. W., & Tessarollo, L. (2006) · Neuron · doi:10.1016/j.neuron.2006.06.009 · Cited by 120 · see citing works

Association Study of Brain‐Derived Neurotrophic Factor Gene Polymorphism and Alcoholism

Matsushita, S., Kimura, M., Miyakawa, T., Yoshino, A., Murayama, M., Masaki, T., & Higuchi, S. (2004) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000145697.81741.d2 · Cited by 117 · see citing works

Postsynaptic signaling networks: Cellular cogwheels underlying long-term plasticity

Blitzer, R. D., Iyengar, R., & Landau, E. M. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.02.031 · Cited by 115 · see citing works

Transcription‐dependent neuronal plasticity

Bading, H. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01565.x · Cited by 112 · see citing works

Association Study of a Brain-Derived Neurotrophic Factor (BDNF) Val66Met Polymorphism and Personality Trait and Intelligence in Healthy Young Females

Tsai, S., Hong, C., Yu, Y. W. ‐., & Chen, T. (2004) · Neuropsychobiology · doi:10.1159/000075333 · Cited by 104 · see citing works

Regulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways

Canossa, M., Gärtner, A., Campana, G., Inagaki, N., & Thoenen, H. (2001) · The EMBO Journal · doi:10.1093/emboj/20.7.1640 · Cited by 103 · see citing works

AMPA protects cultured neurons against glutamate excitotoxicity through a phosphatidylinositol 3‐kinase‐dependent activation in extracellular signal‐regulated kinase to upregulate BDNF gene expression

Wu, X., Zhu, D., Jiang, X., Okagaki, P., Mearow, K. M., Zhu, G., McCall, S. A., Banaudha, K. K., Lipsky, R. H., & Marini, A. M. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02526.x · Cited by 92 · see citing works

Transgenic Mice Overexpressing Truncated trkB Neurotrophin Receptors in Neurons Show Increased Susceptibility to Cortical Injury after Focal Cerebral Ischemia

Saarelainen, T., Lukkarinen, J. A., Koponen, S., Gröhn, O. H. J., Jolkkonen, J., Koponen, E., Haapasalo, A., Alhonen, L. I., Wong, G., Koıstınaho, J., et al. (2000) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2000.0863 · Cited by 87 · see citing works

Results of a genomewide linkage scan: Support for chromosomes 9 and 11 loci increasing risk for cigarette smoking

Gelernter, J. E., Liu, X., HESSELBROCK, V. M., Page, G. P., Goddard, A. W., & Heping Zhang, D. (2004) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30019 · Cited by 86 · see citing works

Truncated TrkB receptor-induced outgrowth of dendritic filopodia involves the p75 neurotrophin receptor

Hartmann, M., Brigadski, T., Erdmann, K. S., Holtmann, B., Sendtner, M., Narz, F., & Leßmann, V. (2004) · Journal of Cell Science · doi:10.1242/jcs.01511 · Cited by 78 · see citing works

Activation of Extracellular Signal‐Regulated Kinase (ERK) and Akt by Human Serotonin 5‐HT 1B Receptors in Transfected BE(2)‐C Neuroblastoma Cells Is Inhibited by RGS4

Lione, A. M., Errico, M., Lin, S. L., & Cowen, D. S. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0750934.x · Cited by 77 · see citing works

An activity‐dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors

Bruno, V., Battaglia, G., Copani, A., Cespédes, V. M., Galindo, M. F., Ceña, V., Sánchez‐Prieto, J., Gasparini, F., Kuhn, R. R., Flor, P. J., et al. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01541.x · Cited by 73 · see citing works

Overexpression of the full-length neurotrophin receptor trkB regulates the expression of plasticity-related genes in mouse brain

Koponen, E., Lakso, M., & Ċastrén, E. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.07.010 · Cited by 68 · see citing works

BDNF genotype potentially modifying the association between incident stroke and depression

Kim, J.-M., Stewart, R., Kim, S.-W., Yang, S.-J., Shin, I.-S., Kim, Y.-H., & Yoon, J.-S. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.11.021 · Cited by 64 · see citing works

Genomic regions linked to alcohol consumption in the Framingham Heart Study

Bergen, A. W., Yang, X. R., Bai, Y., Beerman, M. B., Goldstein, A. M., & Goldin, L. R. (2003) · BMC Genetics · doi:10.1186/1471-2156-4-s1-s101 · Cited by 52 · see citing works

A study of the association of (Val66Met) polymorphism in the Brain-derived Neurotrophic Factor gene with alcohol dependence and extreme violence in Chinese males

Tsai, S., Liao, D., Yu, Y. W. ‐., Chen, T., Wu, H., Lin, C., Cheng, C., & Hong, C. (2005) · Neuroscience Letters · doi:10.1016/j.neulet.2005.02.043 · Cited by 46 · see citing works

Novel monocyclic and bicyclic loop mimetics of brain-derived neurotrophic factor

Fletcher, J. M., & Hughes, R. A. (2006) · Journal of Peptide Science · doi:10.1002/psc.760 · Cited by 45 · see citing works

Nucleotide sequence variation within the human tyrosine kinase B neurotrophin receptor gene: association with antisocial alcohol dependence

Xu, K., Anderson, T. R., Neyer, K. M., Lamparella, N., Jenkins, G. L., Zhou, Z., Yuan, Q., Virkkunen, M. E., & Lipsky, R. H. (2007) · The Pharmacogenomics Journal · doi:10.1038/sj.tpj.6500430 · Cited by 43 · see citing works

Overexpression of a truncated TrkB isoform increases the proliferation of neural progenitors

Tervonen, T. A., Ajamian, F., de Wit, J., Verhaagen, J., Ċastrén, E., & Castrén, M. L. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05010.x · Cited by 43 · see citing works

trkB-Receptor Activation Contributes to the Kainate-Induced Increase in BDNF mRNA Synthesis

Saarelainen, T., Vaittinen, S., & Ċastrén, E. (2001) · Cellular and Molecular Neurobiology · doi:10.1023/a:1012775808253 · Cited by 42 · see citing works

Neocortical neurons lacking the protein-tyrosine kinase B receptor display abnormal differentiation and process elongation in vitro and in vivo

Gates, M. A., Tai, C. C., & Macklis, J. D. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00106-8 · Cited by 41 · see citing works

Short-term treatment with interferon-?/? promotes remyelination, whereas long-term treatment aggravates demyelination in a murine model of multiple sclerosis

Njenga, M. K., Coenen, M. J., DeCuir, N., Yeh, H., & Rodriguez, M. (2000) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(20000301)59:5 · Cited by 35 · see citing works

Behavioral phenotypes: Conceptual and methodological issues

Flint, J. (1998) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19980508)81:3 · Cited by 28 · see citing works

Mapping susceptibility loci for alcohol consumption using number of grams of alcohol consumed per day as a phenotype measure

Ma, J. Z., Zhang, D., Dupont, R. T., Dockter, M. E., Elston, R. C., & Li, M. D. (2003) · BMC Genetics · doi:10.1186/1471-2156-4-s1-s104 · Cited by 27 · see citing works

Electrophysiology and plasticity in isolated postsynaptic densities

Wyneken, Ú., Marengo, J. J., & Orrego, F. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.06.005 · Cited by 14 · see citing works

Telling tails

Kennedy, M. B., & Manzerra, P. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.231486398 · Cited by 14 · see citing works

Delineating and Understanding Cerebellar Neuroprotective Pathways

Wu, X., Jiang, X., Marini, A. M., & Lipsky, R. H. (2005) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2005.tb00009.x · Cited by 12 · see citing works

Delineating and Understanding Cerebellar Neuroprotective Pathways: Potential Implication for Protecting the Cortex

Wu, X. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1344.004 · Cited by 12 · see citing works

Translational Downregulation of the Noncatalytic Growth Factor Receptor TrkB.T1 by Ischemic Preconditioning of Primary Neurons

Steinbeck, J. A., & Methner, A. (2005) · Gene Expression · doi:10.3727/000000005783992142 · Cited by 10 · see citing works

Bridging animal and human models of exercise-induced brain plasticity

Voss, M. W., Vivar, C., Kramer, A. F., & van Praag, H. (2013) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2013.08.001 · Cited by 1,030 · see citing works

Brain-Derived Neurotrophic Factor, Depression, and Physical Activity: Making the Neuroplastic Connection

Phillips, C. (2017) · Neural Plasticity · doi:10.1155/2017/7260130 · Cited by 456 · see citing works

Mitochondria and Neuroplasticity

Cheng, A., Hou, Y., & Mattson, M. P. (2010) · ASN NEURO · doi:10.1042/an20100019 · Cited by 433 · see citing works

Neurobiology and consequences of social isolation stress in animal model—A comprehensive review

Mumtaz, F., Khan, M. I., Zubair, M., & Dehpour, A. R. (2018) · Biomedicine &amp; Pharmacotherapy · doi:10.1016/j.biopha.2018.05.086 · Cited by 369 · see citing works

The Neuromuscular Junction: Aging at the Crossroad between Nerves and Muscle

González‐Freire, M., de Cabo, R., Studenski, S. A., & Ferrucci, L. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00208 · Cited by 361 · see citing works

Relationships of peripheral IGF-1, VEGF and BDNF levels to exercise-related changes in memory, hippocampal perfusion and volumes in older adults

Maaß, A., Düzel, S., Brigadski, T., Goerke, M., Becke, A., Sobieray, U., Neumann, K., Lövdén, M., Lindenberger, U., Bäckman, L., et al. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.10.084 · Cited by 358 · see citing works

Microglia Control Neuronal Network Excitability via BDNF Signalling

Ferrini, F., & Koninck, Y. D. (2013) · Neural Plasticity · doi:10.1155/2013/429815 · Cited by 321 · see citing works

Population genetic study of the brain-derived neurotrophic factor (BDNF) gene

Petryshen, T. L., Sabeti, P. C., Aldinger, K. A., Fry, B., Fan, J. B., Schaffner, S. F., Waggoner, S. G., Tahl, A. R., & Sklar, P. (2010) · Molecular Psychiatry · doi:10.1038/mp.2009.24 · Cited by 267 · see citing works

Glucocorticoid regulation of brain-derived neurotrophic factor: Relevance to hippocampal structural and functional plasticity

Suri, D., & Vaidya, V. A. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.08.065 · Cited by 253 · see citing works

High-intensity interval training evokes larger serum BDNF levels compared with intense continuous exercise

Marquez, C. M. S., Vanaudenaerde, B. M., Troosters, T., & Wenderoth, N. (2015) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00126.2015 · Cited by 243 · see citing works

Pathways Connecting Late-Life Depression and Dementia

Linnemann, C., & Lang, U. E. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00279 · Cited by 212 · see citing works

Chronic vagus nerve stimulation induces neuronal plasticity in the rat hippocampus

Biggio, F., Gorini, G., Utzeri, C., Olla, P., Marrosu, F., Mocchetti, I., & Follesa, P. (2009) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145709000200 · Cited by 203 · see citing works

Effects of aerobic exercise on cognitive performance and individual psychopathology in depressive and schizophrenia patients

Oertel-Knöchel, V., Mehler, P., Thiel, C., Steinbrecher, K., Malchow, B., Tesky, V., Ademmer, K., Prvulovic, D., Banzer, W., Zopf, Y., et al. (2014) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-014-0485-9 · Cited by 185 · see citing works

Neuroinflammation, Microglia and Implications for Retinal Ganglion Cell Survival and Axon Regeneration in Traumatic Optic Neuropathy

Au, N. P. B., & Ma, C. H. E. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.860070 · Cited by 187 · see citing works

BDNF Val66Met polymorphism is associated with HPA axis reactivity to psychological stress characterized by genotype and gender interactions

Shalev, I., Lerer, E., Israel, S., Uzefovsky, F., Gritsenko, I., Mankuta, D., Ebstein, R. P., & Kaitz, M. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.09.017 · Cited by 176 · see citing works

One is the deadliest number: the detrimental effects of social isolation on cerebrovascular diseases and cognition

Friedler, B. D., Crapser, J. D., & McCullough, L. D. (2014) · Acta Neuropathologica · doi:10.1007/s00401-014-1377-9 · Cited by 174 · see citing works

Brain-derived neurotrophic factor in traumatic brain injury, post-traumatic stress disorder, and their comorbid conditions: role in pathogenesis and treatment

Kaplan, G. B., Vasterling, J. J., & Vedak, P. (2010) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e32833d8bc9 · Cited by 163 · see citing works

Extranuclear Estrogen Receptors Mediate the Neuroprotective Effects of Estrogen in the Rat Hippocampus

Yang, L.-C., Zhang, Q.-G., Zhou, C.-F., Yang, F., Zhang, Y.-D., Wang, R.-M., & Brann, D. W. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009851 · Cited by 163 · see citing works

Neural Stem Cells Transfected with Reactive Oxygen Species–Responsive Polyplexes for Effective Treatment of Ischemic Stroke

Jiang, X., Xiang, J., Wu, H., Zhang, T., Zhang, D., Xu, Q., Huang, X., Kong, X., Sun, J., Hu, Y., et al. (2019) · Advanced Materials · doi:10.1002/adma.201807591 · Cited by 158 · see citing works

An acute bout of aerobic or strength exercise specifically modifies circulating exerkine levels and neurocognitive functions in elderly individuals with mild cognitive impairment

Tsai, C., Ukropec, J., Ukropcová, B., & Pai, M. (2017) · NeuroImage Clinical · doi:10.1016/j.nicl.2017.10.028 · Cited by 156 · see citing works

Microglial Involvement in Neuroplastic Changes Following Focal Brain Ischemia in Rats

Madinier, A., Bertrand, N., Mossiat, C. M., Prigent‐Tessier, A., Beley, A., Marie, C., & Garnier, P. E. (2009) · PLoS ONE · doi:10.1371/journal.pone.0008101 · Cited by 154 · see citing works

Time-dependent contribution of non neuronal cells to BDNF production after ischemic stroke in rats

Béjot, Y., Prigent‐Tessier, A., Cachia, C., Giroud, M., Mossiat, C. M., Bertrand, N., Garnier, P. E., & Marie, C. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.10.019 · Cited by 151 · see citing works

Subchronic Alpha-Linolenic Acid Treatment Enhances Brain Plasticity and Exerts an Antidepressant Effect: A Versatile Potential Therapy for Stroke

Blondeau, N., Nguemeni, C., Debruyne, D. N., Piens, M., Wu, X., Pan, H., Hu, X., Gandin, C., Lipsky, R. H., Plumier, J.-C., et al. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.84 · Cited by 148 · see citing works

Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders

Delgado‐Morales, R., Agís‐Balboa, R. C., Esteller, M., & Berdasco, M. (2017) · Clinical Epigenetics · doi:10.1186/s13148-017-0365-z · Cited by 143 · see citing works

Effects of 5-FU

Wigmore, P. M., Mustafa, S., ELBeltagy, M., Lyons, L., Umka, J., & Bennett, G. (2010) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-6306-2_20 · Cited by 148 · see citing works

Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures

Baxendale, S., Holdsworth, C. J., Santoscoy, P. L. M., Harrison, M. R. M., Fox, J., Parkin, C. A., Ingham, P. W., & Cunliffe, V. T. (2012) · Disease Models & Mechanisms · doi:10.1242/dmm.010090 · Cited by 140 · see citing works

Glucocorticoid receptor represses brain-derived neurotrophic factor expression in neuron-like cells

Chen, H., Lombès, M., & Le Menuet, D. (2017) · Molecular Brain · doi:10.1186/s13041-017-0295-x · Cited by 138 · see citing works

Brain-derived neurotrophic factor

Benarroch, E. E. (2015) · Neurology · doi:10.1212/wnl.0000000000001507 · Cited by 135 · see citing works

Low-doses of cisplatin injure hippocampal synapses: A mechanism for ‘chemo’ brain?

Andres, A. L., Gong, X. W., Di, K., & Bota, D. A. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2014.02.020 · Cited by 132 · see citing works

Neuroprotective and neuroproliferative activities of NeuroAid (MLC601, MLC901), a Chinese medicine, in vitro and in vivo

Heurteaux, C., Gandin, C., Borsotto, M., Widmann, C., Brau, F., Lhuillier, M., Onteniente, B., & Lazdunski, M. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.01.001 · Cited by 121 · see citing works

Association Between Val66Met Brain‐Derived Neurotrophic Factor (BDNF) Gene Polymorphism and Post‐Treatment Relapse in Alcohol Dependence

Wojnar, M., Brower, K. J., Strobbe, S., Ilgen, M., Matsumoto, H., Nowosad, I., Sliwerska, E., & Burmeister, M. (2009) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00886.x · Cited by 125 · see citing works

From Molecular to Nanotechnology Strategies for Delivery of Neurotrophins: Emphasis on Brain-Derived Neurotrophic Factor (BDNF)

Géral, C., Angelova, A., & Lesieur, S. (2013) · Pharmaceutics · doi:10.3390/pharmaceutics5010127 · Cited by 124 · see citing works

Sirtuins in neurodegenerative diseases: an update on potential mechanisms

Min, S., Sohn, P., Cho, S.-H., Swanson, R. A., & Gan, L. (2013) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2013.00053 · Cited by 123 · see citing works

Chronic stress and <scp>A</scp> lzheimer's disease: the interplay between the hypothalamic–pituitary–adrenal axis, genetics and microglia

Milligan Armstrong, A., Porter, T., Quek, H., White, A., Haynes, J., Jackaman, C., Villemagne, V., Munyard, K., Laws, S. M., Verdile, G., et al. (2021) · Biological Reviews · doi:10.1111/brv.12750 · Cited by 116 · see citing works

Baicalein attenuates impaired hippocampal neurogenesis and the neurocognitive deficits induced by γ‐ray radiation

Oh, S. B., Park, H. R., Jang, Y. J., Choi, S. Y., Son, T. G., & Lee, J. (2012) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2012.02142.x · Cited by 116 · see citing works

Prior Binge Ethanol Exposure Potentiates the Microglial Response in a Model of Alcohol-Induced Neurodegeneration

Marshall, S. A., Geil, C., & Nixon, K. (2016) · Brain Sciences · doi:10.3390/brainsci6020016 · Cited by 115 · see citing works

The Role of BDNF in Experimental and Clinical Traumatic Brain Injury

Gustafsson, D., Klang, A., Thams, S., & Rostami, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073582 · Cited by 115 · see citing works

Changes in mitochondrial function are pivotal in neurodegenerative and psychiatric disorders: How important is BDNF ?

Markham, A., Bains, R. S., Franklin, P., & Spedding, M. (2013) · British Journal of Pharmacology · doi:10.1111/bph.12531 · Cited by 113 · see citing works

The Role of BDNF as a Biomarker in Cognitive and Sensory Neurodegeneration

Pisani, A., Paciello, F., VECCHIO, V. D., Malesci, R., Corso, E. D., Cantone, E., & Fetoni, A. R. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13040652 · Cited by 120 · see citing works

Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice

Freitas, A. E., Egea, J., Buendía, I., Gómez‐Rangel, V., Parada, E., Navarro, E., Casas, A. I., Wojnicz, A., Ortiz, J. A., Cuadrado, A., et al. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9182-6 · Cited by 107 · see citing works

Neural Substrates of Psychostimulant Withdrawal-Induced Anhedonia

D’Souza, M. S., & Markou, A. (2009) · Current topics in behavioral neurosciences · doi:10.1007/7854_2009_20 · Cited by 107 · see citing works

Basal ganglia and beyond: The interplay between motor and cognitive aspects in Parkinson’s disease rehabilitation

Ferrazzoli, D., Ortelli, P., Madeo, G., Giladi, N., Petzinger, G. M., & Frazzitta, G. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.05.007 · Cited by 105 · see citing works

Reversible epigenetic histone modifications and Bdnf expression in neurons with aging and from a mouse model of Alzheimer’s disease

Walker, M. P., LaFerla, F. M., Oddo, S., & Brewer, G. J. (2012) · AGE · doi:10.1007/s11357-011-9375-5 · Cited by 106 · see citing works

New mechanisms and perspectives in nicotine withdrawal

Jackson, K. J., Muldoon, P. P., Biasi, M. D., & Damaj, M. I. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.11.009 · Cited by 103 · see citing works

Neurobiology of depression: A neurodevelopmental approach

Lima‐Ojeda, J. M., Rupprecht, R., & Baghai, T. C. (2017) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2017.1289240 · Cited by 102 · see citing works

Systematic review of the acute and chronic effects of high-intensity interval training on executive function across the lifespan

Hsieh, S., Chueh, T., Huang, C., Kao, S., Hillman, C. H., Chang, Y., & Hung, T. (2020) · Journal of Sports Sciences · doi:10.1080/02640414.2020.1803630 · Cited by 96 · see citing works

Antidepressant‐like effects of fenofibrate in mice via the hippocampal brain‐derived neurotrophic factor signalling pathway

Jiang, B., Wang, Y., Wang, H., Song, L., Huang, C., Zhu, Q., Wu, F., & Zhang, W. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13668 · Cited by 96 · see citing works

The impact of dietary energy intake on cognitive aging

Mattson, M. P. (2010) · Frontiers in Aging Neuroscience · doi:10.3389/neuro.24.005.2010 · Cited by 91 · see citing works

Physical Exercise for Individuals with Hypertension: It Is Time to Emphasize its Benefits on the Brain and Cognition

Rêgo, M. L. D. M., Cabral, D. A. R., Costa, E. C., & Fontes, E. B. (2019) · Clinical Medicine Insights Cardiology · doi:10.1177/1179546819839411 · Cited by 93 · see citing works

BDNF Therapeutic Mechanisms in Neuropsychiatric Disorders

Bazzari, A. H., & Bazzari, F. H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158417 · Cited by 91 · see citing works

Alteration in BDNF and its receptors, full-length and truncated TrkB and p75NTR following penetrating traumatic brain injury

Rostami, E., Krüeger, F., Plantman, S., Davidsson, J., Agoston, D. V., Grafman, J. H., & Risling, M. (2013) · Brain Research · doi:10.1016/j.brainres.2013.10.047 · Cited by 88 · see citing works

Hippocampal dysfunctions caused by cranial irradiation: A review of the experimental evidence

Son, Y., Yang, M., Wang, H., & Moon, C. (2015) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2015.01.007 · Cited by 84 · see citing works

Brain-derived neurotrophic factor in primary headaches

Fischer, M., Wille, G., Klien, S., Shanib, H., Holle, D., Gaul, C., & Broessner, G. (2012) · The Journal of Headache and Pain · doi:10.1007/s10194-012-0454-5 · Cited by 84 · see citing works

The Migraine Attack as a Homeostatic, Neuroprotective Response to Brain Oxidative Stress: Preliminary Evidence for a Theory

Borkum, J. M. (2017) · Headache The Journal of Head and Face Pain · doi:10.1111/head.13214 · Cited by 83 · see citing works

Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy

Fernández‐García, S., Sancho‐Balsells, A., Longueville, S., Hervé, D., Gruart, A., Delgado-Garcia, J. M., Alberch, J., & Giralt, A. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-2615-9 · Cited by 79 · see citing works

Polymorphisms in the Brain-Derived Neurotrophic Factor Gene Influence Memory and Processing Speed One Month after Brain Injury

McAllister, T. W., Tyler, A. L., Flashman, L. A., Rhodes, C. H., McDonald, B. C., Saykin, A. J., Tosteson, T. D., Tsongalis, G. J., & Moore, J. H. (2011) · Journal of Neurotrauma · doi:10.1089/neu.2011.1930 · Cited by 78 · see citing works

Physical performance and disability in schizophrenia

Strassnig, M., Signorile, J. F., Gonzalez, C., & Harvey, P. D. (2014) · Schizophrenia Research Cognition · doi:10.1016/j.scog.2014.06.002 · Cited by 79 · see citing works

Excitatory GABAergic Activation of Cortical Dividing Glial Cells

Tanaka, Y., Tozuka, Y., Takata, T., Shimazu, N., Matsumura, N., Ohta, A., & Hisatsune, T. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn238 · Cited by 77 · see citing works

The influence of synaptic activity on neuronal health

Bell, K. F., & Hardingham, G. E. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.01.002 · Cited by 77 · see citing works

Post-Traumatic Brain Injury

Davidson, J. M., Cusimano, M. D., & Bendena, W. G. (2014) · The Neuroscientist · doi:10.1177/1073858414543150 · Cited by 77 · see citing works

Characterization of AD-like phenotype in aged APPSwe/PS1dE9 mice

Huang, H., Nie, S., Cao, M., Marshall, C., Gao, J., Xiao, N., Hu, G., & Xiao, M. (2016) · AGE · doi:10.1007/s11357-016-9929-7 · Cited by 75 · see citing works

Opening up the DNA methylome of dementia

Delgado‐Morales, R., & Esteller, M. (2017) · Molecular Psychiatry · doi:10.1038/mp.2016.242 · Cited by 74 · see citing works

BDNF Polymorphism Predicts General Intelligence after Penetrating Traumatic Brain Injury

Rostami, E., Krüeger, F., Zoubak, S., Monte, O. D., Raymont, V., Pardini, M., Hodgkinson, C. A., Goldman, D. A., Risling, M., & Grafman, J. H. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027389 · Cited by 75 · see citing works

A Review of Brain-derived Neurotrophic Factor as a Candidate Biomarker in Schizophrenia

Nurjono, M., Lee, J., & Chong, S. A. (2012) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2012.10.2.61 · Cited by 75 · see citing works

Green tea averts age-dependent decline of hippocampal signaling systems related to antioxidant defenses and survival

Assunção, M., Santos‐Marques, M. J., Carvalho, F. D., & Andrade, J. P. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.01.003 · Cited by 73 · see citing works

Going Too Far Is the Same as Falling Short†: Kinesin-3 Family Members in Hereditary Spastic Paraplegia

Gabrych, D. R., Lau, V. Z., Niwa, S., & Silverman, M. A. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00419 · Cited by 71 · see citing works

Modulation of Synaptic Plasticity by Exercise Training as a Basis for Ischemic Stroke Rehabilitation

Nie, J., & Yang, X. (2016) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-016-0348-1 · Cited by 72 · see citing works

Neural Circuitry Associated with Risk for Alcohol Use Disorders

Tessner, K. D., & Hill, S. Y. (2009) · Neuropsychology Review · doi:10.1007/s11065-009-9111-4 · Cited by 71 · see citing works

The role of microglia in neuropsychiatric disorders and suicide

Brisch, R., Wojtylak, S., Saniotis, A., Steiner, J. H., Gos, T., Kumaratilake, J., Henneberg, M., & Wolf, R. J. (2021) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-021-01334-z · Cited by 71 · see citing works

Rapid Acting Antidepressants in Chronic Stress Models: Molecular and Cellular Mechanisms

Hare, B. D., Ghosal, S., & Duman, R. S. (2017) · Chronic Stress · doi:10.1177/2470547017697317 · Cited by 67 · see citing works

Preclinical Studies Modeling Deep Brain Stimulation for Depression

Hamani, C., & Nóbrega, J. N. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.05.024 · Cited by 68 · see citing works

Understanding epigenetic architecture of suicide neurobiology: A critical perspective

Roy, B., & Dwivedi, Y. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.10.031 · Cited by 69 · see citing works

Long term consequences on spatial learning-memory of low-calorie diet during adolescence in female rats; hippocampal and prefrontal cortex BDNF level, expression of NeuN and cell proliferation in dentate gyrus

Kaptan, Z., Akgün‐Dar, K., Kapucu, A., Dedeakayoğulları, H., Batu, Ş., & Üzüm, G. (2015) · Brain Research · doi:10.1016/j.brainres.2015.05.041 · Cited by 68 · see citing works

Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington’s pathology in zQ175 mice

Abd‐Elrahman, K. S., & Ferguson, S. S. G. (2019) · Molecular Brain · doi:10.1186/s13041-019-0456-1 · Cited by 66 · see citing works

Impact of high intensity interval exercise on executive function and brain derived neurotrophic factor in healthy college aged males

Slusher, A. L., Patterson, V. T., Schwartz, C. S., & Acevedo, E. O. (2018) · Physiology & Behavior · doi:10.1016/j.physbeh.2018.04.018 · Cited by 65 · see citing works

The benefits of exercise on structural and functional plasticity in the rodent hippocampus of different disease models.

Patten, A. R., Yau, S. Y., Fontaine, C. J., Meconi, A., Wortman, R. C., & Christie, B. R. (2015) · Brain Plasticity · doi:10.3233/bpl-150016 · Cited by 64 · see citing works

PLA2G2E-mediated lipid metabolism triggers brain-autonomous neural repair after ischemic stroke

Nakamura, A., Sakai, S., Taketomi, Y., Tsuyama, J., Miki, Y., Hara, Y., Arai, N., Sugiura, Y., Kawaji, H., Murakami, M., et al. (2023) · Neuron · doi:10.1016/j.neuron.2023.06.024 · Cited by 62 · see citing works

Repeated Three-Hour Maternal Separation Induces Depression-Like Behavior and Affects the Expression of Hippocampal Plasticity-Related Proteins in C57BL/6N Mice

Bian, Y., Yang, L., Wang, Z., Wang, Q., Zeng, L., & Xu, G. (2015) · Neural Plasticity · doi:10.1155/2015/627837 · Cited by 61 · see citing works

MicroRNA-124 slows down the progression of Huntington’s disease by promoting neurogenesis in the striatum

Liu, T., Im, W., Mook‐Jung, I., & Kim, M. (2015) · Neural Regeneration Research · doi:10.4103/1673-5374.156978 · Cited by 61 · see citing works

Beneficial effects of dietary restriction in aging brain

Hadem, I. K. H., Majaw, T., Kharbuli, B., & Sharma, R. (2019) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2017.10.001 · Cited by 59 · see citing works

Ultralow doses of cannabinoid drugs protect the mouse brain from inflammation‐induced cognitive damage

Fishbein, M., Gafni, M., & Sarne, Y. (2014) · Journal of Neuroscience Research · doi:10.1002/jnr.23452 · Cited by 59 · see citing works

Insufficient Astrocyte-Derived Brain-Derived Neurotrophic Factor Contributes to Propofol-Induced Neuron Death Through Akt/Glycogen Synthase Kinase 3β/Mitochondrial Fission Pathway

Liu, Y., Yan, Y., Inagaki, Y., Logan, S., Bosnjak, Z. J., & Bai, X. (2017) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000002137 · Cited by 58 · see citing works

Alterations in BDNF and phospho-CREB levels following chronic oral nicotine treatment and its withdrawal in dopaminergic brain areas of mice

Kivinummi, T., Kaste, K., Rantamäki, T., Ċastrén, E., & Ahtee, L. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2011.01.015 · Cited by 57 · see citing works

Hippocampal dysfunction during the chronic phase following a single exposure to cranial irradiation

Son, Y., Yang, M., Kim, J., Kim, J., Kim, S., Kim, J.-C., Shin, T., Wang, H., Jo, S., Jung, U., et al. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2014.01.018 · Cited by 57 · see citing works

Fermented rice peptides attenuate scopolamine-induced memory impairment in mice by regulating neurotrophic signaling pathways in the hippocampus

Corpuz, H. M., Fujii, H., Nakamura, S., & Katayama, S. (2019) · Brain Research · doi:10.1016/j.brainres.2019.146322 · Cited by 57 · see citing works

Alpha-lipoic acid attenuates acute neuroinflammation and long-term cognitive impairment after polymicrobial sepsis

Giustina, A. D., Goldim, M. P. D. S., Danielski, L. G., Florentino, D., Mathias, K., Garbossa, L., de Oliveira, A. N., Fileti, M. E., Zarbato, G. F., da Rosa, N., et al. (2017) · Neurochemistry International · doi:10.1016/j.neuint.2017.06.003 · Cited by 56 · see citing works

A biological perspective on differences and similarities between burnout and depression

Orosz, A., Federspiel, A., Haisch, S., Seeher, C., Dierks, T., & Cattapan, K. (2017) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.12.005 · Cited by 55 · see citing works

BDNF and CGRP interaction: Implications in migraine susceptibility

Lemos, C., Mendonça, D. M., Pereira-Monteiro, J. M., Barros, J., Sequeiros, J., Alonso, I. D. C. M. P., & Sousa, A. (2010) · Cephalalgia · doi:10.1177/0333102410368443 · Cited by 55 · see citing works

Panax ginseng exerts antidepressant-like effects by suppressing neuroinflammatory response and upregulating nuclear factor erythroid 2 related factor 2 signaling in the amygdala

Choi, J. H., Lee, M. J., Jang, M., Kim, H., Lee, S., Lee, S., Kim, Y. O., & Cho, I. (2017) · Journal of Ginseng Research · doi:10.1016/j.jgr.2017.04.012 · Cited by 56 · see citing works

Benefits of Gardening Activities for Cognitive Function According to Measurement of Brain Nerve Growth Factor Levels

Park, S.-A., Lee, A.-Y., Park, H.-G., & Lee, W.-L. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16050760 · Cited by 55 · see citing works

High-intensity physical activity is not associated with better cognition in the elder: evidence from the China Health and Retirement Longitudinal Study

Wu, Z., Zhang, H., Miao, X., Li, H., Pan, H., Zhou, D., Liu, Y., Li, Z., Wang, J., Liu, X., et al. (2021) · Alzheimer s Research & Therapy · doi:10.1186/s13195-021-00923-3 · Cited by 54 · see citing works

Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction

Cristiano, C., Cuozzo, M., Coretti, L., Liguori, F. M., Cimmino, F., Turco, L., Avagliano, C., Aviello, G., Mollica, M. P., Lembo, F., et al. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113528 · Cited by 52 · see citing works

Genetic Influences in Traumatic Brain Injury

Laskowitz, D., & Grant, G. A. (2015) · CRC Press eBooks · doi:10.1201/b18959-14 · Cited by 53 · see citing works

Effects of vitamin D supplementation on neuroplasticity in older adults: a double-blinded, placebo-controlled randomised trial

Pirotta, S., Kidgell, D. J., & Daly, R. M. (2014) · Osteoporosis International · doi:10.1007/s00198-014-2855-6 · Cited by 51 · see citing works

The Role of the Neuroprotective Factor Npas4 in Cerebral Ischemia

Choy, F. C., Klarić, T., Koblar, S. A., & Lewis, M. D. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms161226144 · Cited by 51 · see citing works

Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression

Chong, P. S. R., Poon, C. H., Roy, J., Tsui, K.-C., Lew, S., Phang, M. W. L., Tan, R. J., Cheng, P., Fung, M.-L., Wong, K.-H., et al. (2021) · Chinese Medicine · doi:10.1186/s13020-021-00546-8 · Cited by 43 · see citing works

The Effect of Acute Exercise on Encoding and Consolidation of Long-Term Memory

Labban, J. D., & Etnier, J. L. (2018) · Journal of Sport and Exercise Psychology · doi:10.1123/jsep.2018-0072 · Cited by 48 · see citing works

Upregulation of BDNF and hippocampal functions by a hippocampal ligand of PPARα

Patel, D. R., Roy, A., Raha, S., Kundu, M., Gonzalez, F. J., & Pahan, K. (2020) · JCI Insight · doi:10.1172/jci.insight.136654 · Cited by 48 · see citing works

Genome-Wide Association for Fear Conditioning in an Advanced Intercross Mouse Line

Parker, C. C., Sokoloff, G., Cheng, R., & Palmer, A. A. (2012) · Behavior Genetics · doi:10.1007/s10519-011-9524-8 · Cited by 47 · see citing works

Differential epigenetic regulation of BDNF and NT-3 genes by trichostatin A and 5-aza-2′-deoxycytidine in Neuro-2a cells

Ishimaru, N., Fukuchi, M., Hirai, A., Chiba, Y., Tamura, T., Takahashi, N., Tabuchi, A., Tsuda, M., & Shiraishi, M. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.02.139 · Cited by 47 · see citing works

BDNF V66M Polymorphism and Brain Functions

Chen, Z.-Y. (2014) · Springer eBooks · doi:10.1007/978-1-4614-5836-4_32

Variant BDNF (Val66Met) impact on brain structure and function

Bath, K. G., & Lee, F. S. (2006) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/cabn.6.1.79 · Cited by 325 · see citing works

Brain-derived neurotrophic factor

Laske, C., & Eschweiler, G. W. (2005) · Der Nervenarzt · doi:10.1007/s00115-005-1971-0 · Cited by 76 · see citing works

The Biological Actions and Mechanisms of Brain-Derived Neurotrophic Factor in Healthy and Disordered Brains

Mizui, T., Tanima, Y., Komatsu, H., Kumanogoh, H., & Kojima, M. (2014) · Neuroscience &amp Medicine · doi:10.4236/nm.2014.54021 · Cited by 11 · see citing works

Role of Neurotrophic Factors in Behavioral Processes

Pardon, M. (2010) · Vitamins and hormones · doi:10.1016/s0083-6729(10)82010-2 · Cited by 60 · see citing works