Alterations in the Vaginal Microbiome by Maternal Stress Are Associated With Metabolic Reprogramming of the Offspring Gut and Brain

The gut microbiota shapes intestinal immune responses during health and disease

Round, J. L., & Mazmanian, S. K. (2009) · Nature Reviews Immunology · doi:10.1038/nri2515 · Cited by 5,029

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

Dominguez-Bello, M. G., Costello, E. K., Contreras, M., Magris, M., Hidalgo, G., Fierer, N., & Knight, R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002601107 · Cited by 4,774

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

Cryan, J. F., & Dinan, T. G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3346 · Cited by 4,572

Vaginal microbiome of reproductive-age women

Ravel, J., Gajer, P., Abdo, Z., Schneider, G. M., Koenig, S. S. K., McCulle, S. L., Karlebach, S., Gorle, R., Russell, J., Tacket, C. O., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002611107 · Cited by 4,254

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

Hsiao, E. Y., McBride, S. W., Hsien, S., Sharon, G., Hyde, E. R., McCue, T., Codelli, J. A., Chow, J., Reisman, S. E., Petrosino, J. F., et al. (2013) · Cell · doi:10.1016/j.cell.2013.11.024 · Cited by 3,283

Normal gut microbiota modulates brain development and behavior

Heijtz, R. D., Wang, S., Anuar, F., Qian, Y., Björkholm, B., Samuelsson, A., Hibberd, M. L., Forssberg, H., & Pettersson, S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010529108 · Cited by 3,228

Postnatal microbial colonization programs the hypothalamic–pituitary–adrenal system for stress response in mice

Sudo, N., Chida, Y., Aiba, Y., Sonoda, J., Oyama, N., Yu, X., Kubo, C., & Koga, Y. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.063388 · Cited by 2,735

Succession of microbial consortia in the developing infant gut microbiome

Koenig, J. E., Spor, A., Scalfone, N., Fricker, A. D., Stombaugh, J., Knight, R., Angenent, L. T., & Ley, R. E. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000081107 · Cited by 2,540

The gut microbiota influences blood-brain barrier permeability in mice

Braniste, V., Al-Asmakh, M., Kowal, C., Anuar, F., Abbaspour, A., Tóth, M., Korecka, A., Bakocevic, N., Ng, L. G., Kundu, P., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009759 · Cited by 2,530

Orthogonal projections to latent structures (O‐PLS)

Trygg, J., & Wold, S. (2002) · Journal of Chemometrics · doi:10.1002/cem.695 · Cited by 2,523

The central nervous system and the gut microbiome

Sharon, G., Sampson, T. R., Geschwind, D. H., & Mazmanian, S. K. (2016) · Cell · doi:10.1016/j.cell.2016.10.027 · Cited by 1,513

Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy

Van den Bergh, B. R. H., van den Heuvel, M. I., Lahti, M., Braeken, M., de Rooij, S. R., Entringer, S., Hoyer, D., Roseboom, T., Räikkönen, K., King, S., et al. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.07.003 · Cited by 1,181

Stress & the gut-brain axis: Regulation by the microbiome

Foster, J. A., Rinaman, L., & Cryan, J. F. (2017) · Neurobiology of Stress · doi:10.1016/j.ynstr.2017.03.001 · Cited by 1,150

Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

Kelly, J. R., Kennedy, P. J., Cryan, J. F., Dinan, T. G., Clarke, G., & Hyland, N. P. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00392 · Cited by 1,110

From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways

Rogers, G. B., Keating, D. J., Young, R. L., Wong, M.-L., Licinio, J., & Wesselingh, S. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.50 · Cited by 969

Kynurenine pathway metabolism and the microbiota-gut-brain axis

Kennedy, P. J., Cryan, J. F., Dinan, T. G., & Clarke, G. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.07.002 · Cited by 724

Lipopolysaccharide-induced blood-brain barrier disruption: Roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit

Banks, W. A., Gray, A. M., Erickson, M. A., Salameh, T. S., Damodarasamy, M., Sheibani, N., Meabon, J. S., Wing, E. E., Morofuji, Y., Cook, D. G., et al. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0434-1 · Cited by 636

Emerging Roles for the Gut Microbiome in Autism Spectrum Disorder

Vuong, H. E., & Hsiao, E. Y. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.08.024 · Cited by 595

Anxiety, depression, and the microbiome: A role for gut peptides

Lach, G., Schellekens, H., Dinan, T. G., & Cryan, J. F. (2018) · Neurotherapeutics · doi:10.1007/s13311-017-0585-0 · Cited by 573

The Gut–Brain Axis and the Microbiome: Mechanisms and Clinical Implications

Osadchiy, V., Martin, C. R., & Mayer, E. A. (2019) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2018.10.002 · Cited by 555

Gut microbiota-brain axis

Wang, H.-X., & Wang, Y.-P. (2016) · Chinese Medical Journal · doi:10.4103/0366-6999.190667 · Cited by 546

The microbiome and host behavior

Vuong, H. E., Yano, J. M., Fung, T. C., & Hsiao, E. Y. (2017) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-072116-031347 · Cited by 537

The Microbiota–Gut–Brain Axis in Psychiatric Disorders

Góralczyk-Bińkowska, A., Szmajda‐Krygier, D., & Kozłowska, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911245 · Cited by 569

Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis

Rusch, J. A., Layden, B. T., & Dugas, L. R. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1130689 · Cited by 415

Chronic early life stress induced by limited bedding and nesting (LBN) material in rodents: critical considerations of methodology, outcomes and translational potential

Walker, C., Bath, K. G., Joëls, M., Kőrösi, A., Larauche, M. H., Lucassen, P. J., Morris, M. J., Raineki, C., Roth, T. L., Sullivan, R. M., et al. (2017) · Stress · doi:10.1080/10253890.2017.1343296 · Cited by 432

Prenatal developmental origins of future psychopathology: mechanisms and pathways

Monk, C., Lugo-Candelas, C., & Trumpff, C. (2019) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050718-095539 · Cited by 388

Relationship between the gut microbiome and brain function

Mohajeri, M. H., La Fata, G., Steinert, R. E., & Weber, P. (2018) · Nutrition Reviews · doi:10.1093/nutrit/nuy009 · Cited by 376

Microbiota alteration is associated with the development of stress-induced despair behavior

Marin, I. A., Goertz, J. E., Ren, T., Rich, S. S., Onengut-Gumuscu, S., Farber, E., Wu, M., Overall, C. C., Kipnis, J., & Gaultier, A. (2017) · Scientific Reports · doi:10.1038/srep43859 · Cited by 369

The Host Microbiome Regulates and Maintains Human Health: A Primer and Perspective for Non-Microbiologists

Thomas, S., Izard, J., Walsh, E. K., Batich, K. A., Chongsathidkiet, P., Clarke, G. A., Sela, D. A., Muller, A. J., Mullin, J. M., Albert, K., et al. (2017) · Cancer Research · doi:10.1158/0008-5472.can-16-2929 · Cited by 398

The Role of the Microbiome in the Developmental Origins of Health and Disease

Stiemsma, L. T., & Michels, K. B. (2018) · PEDIATRICS · doi:10.1542/peds.2017-2437 · Cited by 370

Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin

Brown, R. G., Marchesi, J. R., Lee, Y. S., Smith, A., Lehne, B., Kindinger, L. M., Terzidou, V., Holmes, E., Nicholson, J. K., Bennett, P. R., et al. (2018) · BMC Medicine · doi:10.1186/s12916-017-0999-x · Cited by 295

Sex differences in the gut microbiome–brain axis across the lifespan

Jašarević, E., Morrison, K. E., & Bale, T. L. (2016) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2015.0122 · Cited by 306

The prenatal gut microbiome: are we colonized with bacteria in utero ?

Walker, R. W., Clemente, J. C., Peter, I., & Loos, R. J. F. (2017) · Pediatric Obesity · doi:10.1111/ijpo.12217 · Cited by 310

Cross talk: the microbiota and neurodevelopmental disorders

Kelly, J. R., Minuto, C., Cryan, J. F., Clarke, G., & Dinan, T. G. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00490 · Cited by 271

Why do lactobacilli dominate the human vaginal microbiota?

Witkin, S. S., & Linhares, I. M. (2016) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.14390 · Cited by 297

Stress during pregnancy alters temporal and spatial dynamics of the maternal and offspring microbiome in a sex-specific manner

Jašarević, E., Howard, C. D., Misic, A. M., Beiting, D. P., & Bale, T. L. (2017) · Scientific Reports · doi:10.1038/srep44182 · Cited by 262

Intergenerational Transmission of Maternal Childhood Maltreatment Exposure: Implications for Fetal Brain Development

Buss, C., Entringer, S., Moog, N. K., Toepfer, P., Fair, D. A., Simhan, H. N., Heim, C. M., & Wadhwa, P. D. (2017) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2017.03.001 · Cited by 250

The gut microbiota–brain axis in neurological disorder

Ullah, H., Arbab, S., Tian, Y., Liu, C., Chen, Y., Li, Q., Khan, M. I. U., Hassan, I. U., & Li, K. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1225875 · Cited by 292

Vaginal Microbiome and Its Relationship to Behavior, Sexual Health, and Sexually Transmitted Diseases

Lewis, F. M. T., Bernstein, K. T., & Aral, S. O. (2017) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000001932 · Cited by 248

Transfer of maternal psychosocial stress to the fetus

Rakers, F., Rupprecht, S., Dreiling, M., Bergmeier, C., Witte, O. W., & Schwab, M. G. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.02.019 · Cited by 257

The Microbiome in Psychology and Cognitive Neuroscience

Sarkar, A., Harty, S., Lehto, S. M., Moeller, A. H., Dinan, T. G., Dunbar, R., Cryan, J. F., & Burnet, P. W. J. (2018) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2018.04.006 · Cited by 238

The tantalizing links between gut microbes and the brain

Smith, P. A. (2015) · Nature · doi:10.1038/526312a · Cited by 221

Probiotics, Prebiotics, and Synbiotics: Implications and Beneficial Effects against Irritable Bowel Syndrome

Simon, E., Călinoiu, L. F., Mitrea, L., & Vodnar, D. C. (2021) · Nutrients · doi:10.3390/nu13062112 · Cited by 235

N-3 Polyunsaturated Fatty Acids (PUFAs) Reverse the Impact of Early-Life Stress on the Gut Microbiota

Pusceddu, M. M., El Aidy, S., Crispie, F., O’Sullivan, O., Cotter, P., Stanton, C., Kelly, P., Cryan, J. F., & Dinan, T. G. (2015) · PLOS ONE · doi:10.1371/journal.pone.0139721 · Cited by 214

Prenatal stress affects placental cytokines and neurotrophins, commensal microbes, and anxiety-like behavior in adult female offspring

Gur, T. L., Shay, L., Palkar, A. V., Fisher, S., Varaljay, V. A., Dowd, S., & Bailey, M. T. (2017) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2016.12.021 · Cited by 213

A gut (microbiome) feeling about the brain

Sherwin, E., Rea, K., Dinan, T. G., & Cryan, J. F. (2016) · Current Opinion in Gastroenterology · doi:10.1097/mog.0000000000000244 · Cited by 206

Early-life adversity and brain development: Is the microbiome a missing piece of the puzzle?

O’Mahony, S. M., Clarke, G., Dinan, T. G., & Cryan, J. F. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2015.09.068 · Cited by 203

You’ve got male: Sex and the microbiota-gut-brain axis across the lifespan

Jaggar, M., Rea, K., Spichak, S., Dinan, T. G., & Cryan, J. F. (2020) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2019.100815 · Cited by 200

Brain-gut-microbiota axis: challenges for translation in psychiatry

Kelly, J. R., Clarke, G. A., Cryan, J. F., & Dinan, T. G. (2016) · Annals of Epidemiology · doi:10.1016/j.annepidem.2016.02.008 · Cited by 207

Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease

Codagnone, M. G., Spichak, S., O’Mahony, S. M., O’Leary, O. F., Clarke, G., Stanton, C., Dinan, T. G., & Cryan, J. F. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.06.014 · Cited by 198

Fetal, neonatal, and infant microbiome: Perturbations and subsequent effects on brain development and behavior

Heijtz, R. D. (2016) · Seminars in Fetal and Neonatal Medicine · doi:10.1016/j.siny.2016.04.012 · Cited by 201

The maternal vaginal microbiome partially mediates the effects of prenatal stress on offspring gut and hypothalamus

Jašarević, E., Howard, C. D., Morrison, K., Misic, A., Weinkopff, T., Scott, P., Hunter, C., Beiting, D., & Bale, T. L. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0182-5 · Cited by 189

Immune dysfunction and neuroinflammation in autism spectrum disorder

Bjørklund, G., Saad, K., Chirumbolo, S., Kern, J. K., Geier, D. A., Geier, M. R., & Urbina, M. A. (2016) · Acta Neurobiologiae Experimentalis · doi:10.21307/ane-2017-025 · Cited by 188

Harnessing Gut Microbes for Mental Health: Getting From Here to There

Bruce‐Keller, A. J., Salbaum, J. M., & Berthoud, H. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.08.014 · Cited by 192

Do bacteria shape our development? Crosstalk between intestinal microbiota and HPA axis

de Weerth, C. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.09.016 · Cited by 189

Annual Research Review: Critical windows – the microbiota-gut-brain axis in neurocognitive development

Cowan, C. S. M., Dinan, T. G., & Cryan, J. F. (2020) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13156 · Cited by 176

The Role of Gut Dysbiosis in the Pathophysiology of Neuropsychiatric Disorders

Anand, N., Gorantla, V. R., & Chidambaram, S. B. (2022) · Cells · doi:10.3390/cells12010054 · Cited by 194

From Probiotics to Psychobiotics: Live Beneficial Bacteria Which Act on the Brain-Gut Axis

Bermúdez‐Humarán, L. G., Salinas, E., Ortíz, G. G., Ramírez-Jirano, L. J., Morales, J. A., & Bitzer-Quintero, O. K. (2019) · Nutrients · doi:10.3390/nu11040890 · Cited by 184

Multifaceted origins of sex differences in the brain

McCarthy, M. M. (2016) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2015.0106 · Cited by 176

The contribution of the gut microbiome to neurodevelopment and neuropsychiatric disorders

Warner, B. B. (2018) · Pediatric Research · doi:10.1038/s41390-018-0191-9 · Cited by 171

Understanding the gut microbiome of dairy calves: Opportunities to improve early-life gut health

Malmuthuge, N., & Guan, L. L. (2017) · Journal of Dairy Science · doi:10.3168/jds.2016-12239 · Cited by 173

Translating basic research knowledge on the biological embedding of early-life stress into novel approaches for the developmental programming of lifelong health

Heim, C. M., Entringer, S., & Buss, C. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.12.011 · Cited by 158

Childhood adversity impact on gut microbiota and inflammatory response to stress during pregnancy

Hantsoo, L., Jašarević, E., Criniti, S., McGeehan, B., Tanes, C., Sammel, M. D., Elovitz, M. A., Compher, C., Wu, G., & Epperson, C. N. (2019) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.11.005 · Cited by 156

A gut feeling: Microbiome-brain-immune interactions modulate social and affective behaviors

Sylvia, K. E., & Demas, G. E. (2018) · Hormones and Behavior · doi:10.1016/j.yhbeh.2018.02.001 · Cited by 154

Host contributes to longitudinal diversity of fecal microbiota in swine selected for lean growth

Lu, D., Tiezzi, F., Schillebeeckx, C., McNulty, N. P., Schwab, C. R., Shull, C. M., & Maltecca, C. (2018) · Microbiome · doi:10.1186/s40168-017-0384-1 · Cited by 163

Socioeconomic Status and the Gut Microbiome: A TwinsUK Cohort Study

Bowyer, R. C. E., Jackson, M. A., Le Roy, C. I., Ni Lochlainn, M., Spector, T. D., Dowd, J. B., & Steves, C. J. (2019) · Microorganisms · doi:10.3390/microorganisms7010017 · Cited by 150

Targeting gut microbiome: a novel and potential therapy for autism

Yang, Y., Tian, J., & Yang, B. (2018) · Life Sciences · doi:10.1016/j.lfs.2017.12.027 · Cited by 140

The role of the microbiome in the neurobiology of social behaviour

Sarkar, A., Harty, S., Johnson, K. V. ‐., Moeller, A. H., Carmody, R. N., Lehto, S. M., Erdman, S. E., Dunbar, R. I. M., & Burnet, P. W. J. (2020) · Biological Reviews · doi:10.1111/brv.12603 · Cited by 135

Chronic Early-life Stress in Rat Pups Alters Basal Corticosterone, Intestinal Permeability, and Fecal Microbiota at Weaning: Influence of Sex

Moussaoui, N., Jacobs, J., Larauche, M., Biraud, M., Million, M., Mayer, E., & Taché, Y. (2017) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm16105 · Cited by 118

Prenatal stress disrupts social behavior, cortical neurobiology and commensal microbes in adult male offspring

Gur, T. L., Palkar, A. V., Rajasekera, T., Allen, J., Niraula, A., Godbout, J., & Bailey, M. T. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.06.025 · Cited by 127

Prenatal and postnatal contributions of the maternal microbiome on offspring programming

Jašarević, E., & Bale, T. L. (2019) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2019.100797 · Cited by 131

The female reproductive tract microbiotas, inflammation, and gynecological conditions

Gholiof, M., Luca, E. A.-D., & Wessels, J. M. (2022) · Frontiers in Reproductive Health · doi:10.3389/frph.2022.963752 · Cited by 137

Maternal anxiety, depression and stress affects offspring gut microbiome diversity and bifidobacterial abundances

Galley, J. D., Mashburn‐Warren, L., Blalock, L. C., Lauber, C. L., Carroll, J., Ross, K. M., Hobel, C. J., Coussons‐Read, M. E., Schetter, C. D., & Gur, T. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2022.10.005 · Cited by 128

Prenatal exposure to environmental insults and enhanced risk of developing Schizophrenia and Autism Spectrum Disorder: focus on biological pathways and epigenetic mechanisms

Cattane, N., Richetto, J., & Cattaneo, A. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.07.001 · Cited by 129

Roles of the Microbiota of the Female Reproductive Tract in Gynecological and Reproductive Health

Zhu, B., Tao, Z., Edupuganti, L., Serrano, M. G., & Buck, G. A. (2022) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00181-21 · Cited by 131

Inflammatory Bowel Disease: A Stressed “Gut/Feeling”

Oligschlaeger, Y., Yadati, T., Houben, T., Oliván, C. M. C., & Shiri‐Sverdlov, R. (2019) · Cells · doi:10.3390/cells8070659 · Cited by 121

Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress

Nasca, C., Bigio, B., Zelli, D., de Angelis, P., Lau, T., Okamoto, M., Soya, H., Ni, J., Brichta, L., Greengard, P., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.09.020 · Cited by 113

Commensal bacteria‐immunity crosstalk shapes mucosal homeostasis in teleost fish

Yu, Y., Ding, L., Huang, Z., Xu, H., & Xu, Z. (2021) · Reviews in Aquaculture · doi:10.1111/raq.12570 · Cited by 121

The role of the gut microbiome in the development of schizophrenia

Kelly, J. R., Minuto, C., Cryan, J. F., Clarke, G. A., & Dinan, T. G. (2020) · Schizophrenia Research · doi:10.1016/j.schres.2020.02.010 · Cited by 121

Cortisol-Related Signatures of Stress in the Fish Microbiome

Webster, T. M. U., Rodríguez‐Barreto, D., Consuegra, S., & de Leániz, C. G. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.01621 · Cited by 112

The Potential Influence of the Bacterial Microbiome on the Development and Progression of ADHD

Bull-Larsen, S., & Mohajeri, M. H. (2019) · Nutrients · doi:10.3390/nu11112805 · Cited by 111

Maternal gut and fetal brain connection: Increased anxiety and reduced social interactions in Wistar rat offspring following peri-conceptional antibiotic exposure

Degroote, S., Hunting, D. J., Baccarelli, A. A., & Takser, L. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.06.010 · Cited by 106

Gut Microbiota Interaction with the Central Nervous System throughout Life

Ojeda, J., Ávila, A., & Vidal, P. M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10061299 · Cited by 112

The Interplay of Host Immunity, Environment and the Risk of Bacterial Vaginosis and Associated Reproductive Health Outcomes

Murphy, K., & Mitchell, C. M. (2016) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiw140 · Cited by 101

Pathways of Association from Stress to Obesity in Early Childhood

Miller, A. L., & Lumeng, J. C. (2018) · Obesity · doi:10.1002/oby.22155 · Cited by 109

Maternal Folic Acid Supplementation Mediates Offspring Health via DNA Methylation

Liu, H.-Y., Liu, S., & Zhang, Y. (2020) · Reproductive Sciences · doi:10.1007/s43032-020-00161-2 · Cited by 99

The modulatory effect of plant polysaccharides on gut flora and the implication for neurodegenerative diseases from the perspective of the microbiota-gut-brain axis

Sun, Q., Cheng, L., Zeng, X., Zhang, X., Wu, Z., & Weng, P. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.07.208 · Cited by 98

Neurobehavioral comorbidities of epilepsy: Role of inflammation

Mazarati, A. M., Lewis, M. L., & Pittman, Q. J. (2017) · Epilepsia · doi:10.1111/epi.13786 · Cited by 96

Psychosocial Stress, Cortisol Levels, and Maintenance of Vaginal Health

Amabebe, E., & Anumba, D. O. C. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00568 · Cited by 107

Interactions between reproductive biology and microbiomes in wild animal species

Comizzoli, P., Power, M. L., Bornbusch, S. L., & Muletz‐Wolz, C. R. (2021) · Animal Microbiome · doi:10.1186/s42523-021-00156-7 · Cited by 96

Intervention strategies for cesarean section–induced alterations in the microbiota-gut-brain axis

Moya-Pérez, Á., Luczynski, P., Renes, I. B., Wang, S., Borre, Y. E., Ryan, C. A., Knol, J., Stanton, C., Dinan, T. G., & Cryan, J. F. (2017) · Nutrition Reviews · doi:10.1093/nutrit/nuw069 · Cited by 100

The connection between microbiome and schizophrenia

Golofast, B., & Vales, K. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.12.011 · Cited by 92

Gut microbiota and central nervous system development

Principi, N., & Esposito, S. (2016) · Journal of Infection · doi:10.1016/j.jinf.2016.09.010 · Cited by 92

Probiotic, Prebiotic, and Brain Development

Cerdó, T., Ruiz-Rodriguez, A., Suárez, A., & Campoy, C. (2017) · Nutrients · doi:10.3390/nu9111247 · Cited by 103

Targeting the gut microbiota to influence brain development and function in early life

Wang, S., Harvey, L., Martı́n, R., van der Beek, E. M., Knol, J., Cryan, J. F., & Renes, I. B. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.09.002 · Cited by 97

Stress gets into the belly: Early life stress and the gut microbiome

Hantsoo, L. V., & Zemel, B. S. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113474 · Cited by 97

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