Intergenerational Transmission of Maternal Childhood Maltreatment Exposure: Implications for Fetal Brain Development
Open accessAbstract
Objective Growing evidence suggests the deleterious consequences of exposure to childhood maltreatment (CM) not only might endure over the exposed individual's lifespan but also might be transmitted across generations. The time windows, mechanisms, and targets of such intergenerational transmission are poorly understood. The prevailing paradigm posits that mother-to-child transmission of the effects of maternal CM likely occurs after her child's birth. The authors seek to extend this paradigm and advance a transdisciplinary framework that integrates the concepts of biological embedding of life experiences and fetal origins of health and disease risk.Method The authors posit that the period of embryonic and fetal life represents a particularly sensitive time for intergenerational transmission; that the developing brain represents a target of particular interest; and that stress-sensitive maternal-placental-fetal biological (endocrine, immune) pathways represent leading candidate mechanisms of interest.Results The plausibility of this model is supported by theoretical considerations and empirical findings in humans and animals. The authors synthesize several research areas and identify important knowledge gaps that might warrant further study.Conclusion The scientific and public health relevance of this effort relates to achieving a better understanding of the "when," "what," and "how" of intergenerational transmission of CM, with implications for early identification of risk, prevention, and intervention.
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An intergenerational impact of child maltreatment can be observed shortly after birth.
“as findings [57] show that an intergenerational impact of child maltreatment can be observed shortly after birth.”
From Psychoanalytic Interventions with Abusive Parents: An Opportunity for Children’s Mental Health (2022) · cites this paper as [57]
These effects might not be restricted to one's own lifespan but may also be transmitted to offspring.
“In line with what has been observed in rodent studies [131], these effects might not be restricted to one’s own lifespan but may also be transmitted to offspring [132].”
From Food Addiction and Psychosocial Adversity: Biological Embedding, Contextual Factors, and Public Health Implications (2020) · cites this paper as [132]
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Felitti, V. J., Anda, R. F., Nordenberg, D., Williamson, D. F., Spitz, A. M., Edwards, V., Koss, M. P., & Marks, J. S. (1998) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(98)00017-8 · Cited by 18,943 · see citing works
Child abuse: Adolescent records vs. adult recall
Femina, D. D., Yeager, C. A., & Lewis, D. O. (1990) · Child Abuse & Neglect · doi:10.1016/0145-2134(90)90033-p · Cited by 8,820 · see citing works
Effects of stress throughout the lifespan on the brain, behaviour and cognition
Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2639 · Cited by 6,256 · see citing works
Self-citationAnda, R. F., Felitti, V. J., Bremner, J. D., Walker, J. D., Whitfield, C., Perry, B. D., Dube, S. R., & Giles, W. H. (2006) · European archives of psychiatry and clinical neuroscience · doi:10.1007/s00406-005-0624-4 · Cited by 4,292 · see citing works
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
McGowan, P. O., Sasaki, A., D'Alessio, A. C., Dymov, S., Labonté, B., Szyf, M., Turecki, G., & Meaney, M. J. (2009) · Nature Neuroscience · doi:10.1038/nn.2270 · Cited by 3,531 · see citing works
Heim, C., & Nemeroff, C. B. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01157-x · Cited by 2,791 · see citing works
Self-citationGenetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Cross-Disorder Group of the Psychiatric Genomics Consortium (2013) · Nature Genetics · doi:10.1038/ng.2711 · Cited by 2,263 · see citing works
Miller, G. E., Chen, E., & Parker, K. J. (2011) · Psychological Bulletin · doi:10.1037/a0024768 · Cited by 1,785 · see citing works
The link between childhood trauma and depression: insights from HPA axis studies in humans
Heim, C., Newport, D. J., Mletzko, T., Miller, A. H., & Nemeroff, C. B. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.03.008 · Cited by 1,704 · see citing works
Self-citationAllele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions
Klengel, T., Mehta, D., Anacker, C., Rex-Haffner, M., Pruessner, J. C., Pariante, C. M., Pace, T. W. W., Mercer, K. B., Mayberg, H. S., Bradley, B., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3275 · Cited by 1,447 · see citing works
Self-citationImplication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice
Gapp, K., Jawaid, A., Sarkies, P., Bohacek, J., Pelczar, P., Prados, J., Farinelli, L., Miska, E., & Mansuy, I. M. (2014) · Nature Neuroscience · doi:10.1038/nn.3695 · Cited by 1,306 · see citing works
Childhood maltreatment predicts adult inflammation in a life-course study
Danese, A., Pariante, C. M., Caspi, A., Taylor, A., & Poulton, R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610362104 · Cited by 1,264 · see citing works
Finkelhor, D., Turner, H. A., Shattuck, A., & Hamby, S. L. (2015) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2015.0676 · Cited by 1,264 · see citing works
Maternal immune activation: Implications for neuropsychiatric disorders
Estes, M. L., & McAllister, A. K. (2016) · Science · doi:10.1126/science.aag3194 · Cited by 1,206 · see citing works
Genetic architectures of psychiatric disorders: the emerging picture and its implications
Sullivan, P. F., Daly, M. J., & O'Donovan, M. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3240 · Cited by 1,177 · see citing works
A Structural MRI Study of Human Brain Development from Birth to 2 Years
Knickmeyer, R. C., Gouttard, S., Kang, C., Evans, D., Wilber, K., Smith, J. K., Hamer, R. M., Lin, W., Gerig, G., & Gilmore, J. H. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.3479-08.2008 · Cited by 1,151 · see citing works
Epigenetic transmission of the impact of early stress across generations
Franklin, T. B., Russig, H., Weiss, I. C., Gräff, J., Linder, N., Michalon, A., Vizi, S., & Mansuy, I. M. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.05.036 · Cited by 1,125 · see citing works
A mega-analysis of genome-wide association studies for major depressive disorder
Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, Ripke, S., Wray, N. R., Lewis, C. M., Hamilton, S. P., Weissman, M. M., Breen, G., Byrne, E. M., Blackwood, D. H. R., Boomsma, D. I., et al. (2013) · Molecular Psychiatry · doi:10.1038/mp.2012.21 · Cited by 1,120 · see citing works
Monk, M., Boubelı́k, M., & Lehnert, S. A. (1987) · Development · doi:10.1242/dev.99.3.371 · Cited by 1,100 · see citing works
Childhood abuse and lifetime psychopathology in a community sample
MacMillan, H. L., Fleming, J. E., Streiner, D. L., Lin, E., Boyle, M. H., Jamieson, E., Duku, E. K., Walsh, C. A., Wong, M. Y.-Y., & Beardslee, W. R. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.11.1878 · Cited by 1,035 · see citing works
Heim, C., & Binder, E. B. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2011.10.032 · Cited by 986 · see citing works
Self-citationWadhwa, P. D., Buß, C., Entringer, S., & Swanson, J. (2009) · Seminars in Reproductive Medicine · doi:10.1055/s-0029-1237424 · Cited by 986 · see citing works
Self-citationThe Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells
Seisenberger, S., Andrews, S., Krueger, F., Arand, J., Walter, J., Santos, F., Popp, C., Thienpont, B., Dean, W., & Reik, W. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.11.001 · Cited by 973 · see citing works
Springer, K. W., Sheridan, J., Kuo, D., & Carnes, M. (2007) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2007.01.003 · Cited by 964 · see citing works
A unique regulatory phase of DNA methylation in the early mammalian embryo
Smith, Z. D., Chan, M. M., Mikkelsen, T. S., Gu, H., Gnirke, A., Regev, A., & Meissner, A. (2012) · Nature · doi:10.1038/nature10960 · Cited by 964 · see citing works
Hussey, J. M., Chang, J. J., & Kotch, J. (2006) · Pediatrics · doi:10.1542/peds.2005-2452 · Cited by 895 · see citing works
Maternal immune activation and abnormal brain development across CNS disorders
Knuesel, I., Chicha, L., Britschgi, M., Schobel, S. A., Bodmer, M., Hellings, J. A., Toovey, S., & Prinssen, E. P. (2014) · Nature Reviews Neurology · doi:10.1038/nrneurol.2014.187 · Cited by 880 · see citing works
Pace, T. W. W., Mletzko, T. C., Alagbe, O., Musselman, D. L., Nemeroff, C. B., Miller, A. H., & Heim, C. M. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.9.1630 · Cited by 810 · see citing works
Self-citationHeim, C., Newport, D. J., Bonsall, R., Miller, A. H., & Nemeroff, C. B. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.4.575 · Cited by 746 · see citing works
Self-citationDynamic CpG island methylation landscape in oocytes and preimplantation embryos
Smallwood, S. A., Tomizawa, S.-I., Krueger, F., Ruf, N., Carli, N., Segonds-Pichon, A., Sato, S., Hata, K., Andrews, S., & Kelsey, G. (2011) · Nature Genetics · doi:10.1038/ng.864 · Cited by 701 · see citing works
Understanding transgenerational epigenetic inheritance via the gametes in mammals
Daxinger, L., & Whitelaw, E. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3188 · Cited by 700 · see citing works
Nusslock, R., & Miller, G. E. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.05.017 · Cited by 672 · see citing works
Buss, C., Davis, E. P., Shahbaba, B., Pruessner, J. C., Head, K., & Sandman, C. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1201295109 · Cited by 652 · see citing works
Elevated inflammation levels in depressed adults with a history of childhood maltreatment
Danese, A., Moffitt, T. E., Pariante, C. M., Ambler, A., Poulton, R., & Caspi, A. (2008) · Archives of General Psychiatry · doi:10.1001/archpsyc.65.4.409 · Cited by 641 · see citing works
Prenatal exposure to maternal depression and cortisol influences infant temperament
DAVIS, E. P., GLYNN, L. M., SCHETTER, C. D., HOBEL, C., CHICZ-DEMET, A., & SANDMAN, C. A. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e318047b775 · Cited by 628 · see citing works
Developmental origins of disease paradigm: A mechanistic and evolutionary perspective
Gluckman, P. D., & Hanson, M. A. (2004) · Pediatric Research · doi:10.1203/01.pdr.0000135998.08025.fb · Cited by 607 · see citing works
Jaffee, S. R., & Price, T. S. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001950 · Cited by 577 · see citing works
Glucocorticoids and fetal programming part 1: outcomes
Moisiadis, V. G., & Matthews, S. G. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.73 · Cited by 571 · see citing works
Lower CSF oxytocin concentrations in women with a history of childhood abuse
Heim, C., Young, L. J., Newport, D. J., Mletzko, T., Miller, A. H., & Nemeroff, C. B. (2009) · Molecular Psychiatry · doi:10.1038/mp.2008.112 · Cited by 518 · see citing works
Self-citationBabenko, O., Kovalchuk, I., & Metz, G. A. S. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.11.013 · Cited by 513 · see citing works
Glucocorticoids and fetal programming part 2: mechanisms
Moisiadis, V. G., & Matthews, S. G. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.74 · Cited by 448 · see citing works
Wray, N. R., Pergadia, M. L., Blackwood, D. H. R., Penninx, B. W. J. H., Gordon, S. D., Nyholt, D. R., Ripke, S., MacIntyre, D. J., McGhee, K. A., Maclean, A. W., et al. (2012) · Molecular Psychiatry · doi:10.1038/mp.2010.109 · Cited by 444 · see citing works
Costs of Health Care Use by Women HMO Members With a History of Childhood Abuse and Neglect
Walker, E. A., Unützer, J., Rutter, C. M., Gelfand, A. N., Saunders, K. W., VonKorff, M., Koss, M. P., & Katon, W. J. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.7.609 · Cited by 442 · see citing works
Kiecolt-Glaser, J. K., Gouin, J.-P., Weng, N.-P., Malarkey, W. B., Beversdorf, D. Q., & Glaser, R. (2011) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31820573b6 · Cited by 430 · see citing works
Psychoneuroimmunology of early-life stress: the hidden wounds of childhood trauma?
Danese, A., & J Lewis, S. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.198 · Cited by 393 · see citing works
Teh, A. L., Pan, H., Chen, L., Ong, M.-L., Dogra, S., Wong, J., MacIsaac, J. L., Mah, S. M., McEwen, L. M., Saw, S.-M., et al. (2014) · Genome Research · doi:10.1101/gr.171439.113 · Cited by 352 · see citing works
Dietz, P. M., Williams, S. B., Callaghan, W. M., Bachman, D. J., Whitlock, E. P., & Hornbrook, M. C. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06111893 · Cited by 350 · see citing works
Zhang, T. Y., Labonté, B., Wen, X. L., Turecki, G., & Meaney, M. J. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2012.149 · Cited by 347 · see citing works
Rearing effects on cerebrospinal fluid oxytocin concentration and social buffering in rhesus monkeys
Winslow, J. T., Noble, P. L., Lyons, C. K., Sterk, S. M., & Insel, T. R. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300128 · Cited by 345 · see citing works
Adverse childhood experiences reported by adults - five states, 2009.
Bynum, L. A., Griffin, T., Riding, D., Wynkoop, K. S., Anda, R. F., Edwards, V., Strine, T. W., Liu, Y., McKnight-Eily, L. R., & Croft, J. B. (2010) · MMWR Morbidity and Mortality Weekly Report · Cited by 331 · see citing works
Obesity and Type 2 Diabetes Risk in Midadult Life: The Role of Childhood Adversity
Thomas, C., Hyppönen, E., & Power, C. (2008) · Pediatrics · doi:10.1542/peds.2007-2403 · Cited by 330 · see citing works
Jašarević, E., Howerton, C. L., Howard, C. D., & Bale, T. L. (2015) · Endocrinology · doi:10.1210/en.2015-1177 · Cited by 329 · see citing works
Prevalence and demographic correlates of childhood maltreatment in an adult community sample
Scher, C. D., Forde, D. R., McQuaid, J. R., & Stein, M. B. (2004) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2003.09.012 · Cited by 329 · see citing works
Pembrey, M., Saffery, R., Bygren, L. O., & Network in Epigenetic Epidemiology (2014) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2014-102577 · Cited by 325 · see citing works
Entringer, S., Buss, C., & Wadhwa, P. D. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.08.019 · Cited by 324 · see citing works
Self-citationChildhood victimization and drug abuse: A comparison of prospective and retrospective findings.
Widom, C. S., Weiler, B. L., & Cottler, L. B. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.67.6.867 · Cited by 322 · see citing works
Afifi, T. O., Boman, J., Fleisher, W., & Sareen, J. (2009) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2008.12.009 · Cited by 310 · see citing works
The role of DNA methylation in stress-related psychiatric disorders
Klengel, T., Pape, J., Binder, E. B., & Mehta, D. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.01.013 · Cited by 309 · see citing works
Hanson, M. A., Godfrey, K. M., Lillycrop, K. A., Burdge, G. C., & Gluckman, P. D. (2011) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2010.12.008 · Cited by 298 · see citing works
Sandman, C. A., Davis, E. P., Buß, C., & Glynn, L. M. (2011) · Neuroendocrinology · doi:10.1159/000327017 · Cited by 293 · see citing works
Maternal pregnancy-specific anxiety is associated with child executive function at 6–9 years age
Buss, C., Davis, E. P., Hobel, C. J., & Sandman, C. A. (2011) · Stress · doi:10.3109/10253890.2011.623250 · Cited by 289 · see citing works
Wu, L., Russell, D. L., Wong, S. L., Chen, M., Tsai, T., John, J. C. S., Norman, R. J., Febbraio, M. A., Carroll, J., & Robker, R. L. (2015) · Development · doi:10.1242/dev.114850 · Cited by 276 · see citing works
The effects of early life stress on the epigenome: From the womb to adulthood and even before
Provençal, N., & Binder, E. B. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2014.09.001 · Cited by 255 · see citing works
Hinde, K., Skibiel, A. L., Foster, A. B., Rosso, L. A. D., Mendoza, S. P., & Capitanio, J. P. (2014) · Behavioral Ecology · doi:10.1093/beheco/aru186 · Cited by 254 · see citing works
Revictimization rates and method variance
Roodman, A. A., & Clum, G. A. (2001) · Clinical Psychology Review · doi:10.1016/s0272-7358(99)00045-8 · Cited by 246 · see citing works
Heim, C. (2009) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.041.2009 · Cited by 245 · see citing works
Self-citationPalma-Gudiel, H., Córdova-Palomera, A., Eixarch, E., Deuschle, M., & Fañanás, L. (2015) · Epigenetics · doi:10.1080/15592294.2015.1088630 · Cited by 240 · see citing works
Entringer, S., Buß, C., & Wadhwa, P. D. (2010) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e3283405921 · Cited by 236 · see citing works
Self-citationAdverse childhood experiences reported by adults --- five states, 2009.
(2010) · PubMed · Cited by 236 · see citing works
Stress In Utero: Prenatal Programming of Brain Plasticity and Cognition
Bock, J., Wainstock, T., Braun, K., & Segal, M. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.02.036 · Cited by 232 · see citing works
A Reexamination of Smoking Before, During, and After Pregnancy
Kahn, R. S., Certain, L., & Whitaker, R. C. (2002) · American Journal of Public Health · doi:10.2105/ajph.92.11.1801 · Cited by 216 · see citing works
Carpenter, L. L., Tyrka, A. R., McDougle, C. J., Malison, R. T., Owens, M. J., Nemeroff, C. B., & Price, L. H. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300375 · Cited by 209 · see citing works
Prenatal programing: At the intersection of maternal stress and immune activation
Howerton, C. L., & Bale, T. L. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.03.007 · Cited by 205 · see citing works
Metabolic control of oocyte development: linking maternal nutrition and reproductive outcomes
Gu, L., Liu, H., Gu, X., Boots, C. E., Moley, K. H., & Wang, Q. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1739-4 · Cited by 204 · see citing works
Intergenerational transmission of maltreatment and psychopathology: the role of antenatal depression
Plant, D. T., Barker, E. D., Waters, C. S., Pawlby, S., & Pariante, C. M. (2013) · Psychological Medicine · doi:10.1017/s0033291712001298 · Cited by 201 · see citing works
Prenatal Programming of Human Neurological Function
Sandman, C. A., Davis, E. P., Buß, C., & Glynn, L. M. (2011) · International Journal of Peptides · doi:10.1155/2011/837596 · Cited by 201 · see citing works
Buss, C., Lord, C., Wadiwalla, M., Hellhammer, D. H., Lupien, S. J., Meaney, M. J., & Pruessner, J. C. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.3252-06.2007 · Cited by 187 · see citing works
Pace, T. W. W., Wingenfeld, K., Schmidt, I., Meinlschmidt, G., Hellhammer, D. H., & Heim, C. M. (2012) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2011.07.232 · Cited by 184 · see citing works
Self-citationEntringer, S., Buß, C., Shirtcliff, E. A., Cammack, A. L., Yim, I. S., Chicz-DeMet, A., Sandman, C. A., & Wadhwa, P. D. (2010) · Stress · doi:10.3109/10253890903349501 · Cited by 180 · see citing works
Self-citationEarly childhood adversity and pregnancy outcomes
Smith, M. V., Gotman, N., & Yonkers, K. A. (2016) · Maternal and Child Health Journal · doi:10.1007/s10995-015-1909-5 · Cited by 175 · see citing works
Brand, S. R., Brennan, P. A., Newport, D. J., Smith, A. K., Weiss, T., & Stowe, Z. N. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.10.009 · Cited by 170 · see citing works
Entringer, S., Buß, C., Swanson, J. M., Cooper, D. M., Wing, D. A., Waffarn, F., & Wadhwa, P. D. (2012) · Journal of Nutrition and Metabolism · doi:10.1155/2012/632548 · Cited by 165 · see citing works
Self-citationLevinson, D. F., Mostafavi, S., Milaneschi, Y., Rivera, M., Ripke, S., Wray, N. R., & Sullivan, P. F. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.07.029 · Cited by 159 · see citing works
Association of Maternal Exposure to Childhood Abuse With Elevated Risk for Autism in Offspring
Roberts, A. L., Lyall, K., Rich-Edwards, J. W., Ascherio, A., & Weisskopf, M. G. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.447 · Cited by 152 · see citing works
Maternal DNA Methylation Regulates Early Trophoblast Development
Branco, M. R., King, M. R., Pérez-García, V., Bogutz, A., Caley, M. P., Fineberg, E., Lefebvre, L., Cook, S. J., Dean, W., Hemberger, M., et al. (2016) · Developmental Cell · doi:10.1016/j.devcel.2015.12.027 · Cited by 146 · see citing works
Maternal childhood abuse and offspring adjustment over time
Collishaw, S., Dunn, J., O’Connor, T. G., Golding, J., & THE AVON LONGITUDINAL STUDY OF PARENTS AND CHILDREN STUDY TEAM (2007) · Development and Psychopathology · doi:10.1017/s0954579407070186 · Cited by 139 · see citing works
Buß, C., Entringer, S., & Wadhwa, P. D. (2012) · Science Signaling · doi:10.1126/scisignal.2003406 · Cited by 131 · see citing works
Self-citationMoog, N. K., Buss, C., Entringer, S., Shahbaba, B., Gillen, D. L., Hobel, C. J., & Wadhwa, P. D. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.08.032 · Cited by 129 · see citing works
Self-citationOocyte Maturation: The Coming of Age of a Germ Cell
Jamnongjit, M., & Hammes, S. R. (2005) · Seminars in Reproductive Medicine · doi:10.1055/s-2005-872451 · Cited by 122 · see citing works
Sánchez-Delgado, M., Court, F., Vidal, E., Medrano, J. V., Monteagudo, A., Martín-Trujillo, Á., Tayama, C., Iglesias‐Platas, I., Kondova, I. I., Bontrop, R. E., et al. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1006427 · Cited by 121 · see citing works
Models of Intergenerational and Transgenerational Transmission of Risk for Psychopathology in Mice
Klengel, T., Dias, B. G., & Ressler, K. J. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.249 · Cited by 118 · see citing works
The Impact of Maternal Childhood Abuse on Parenting and Infant Temperament
Lang, A. J., Gartstein, M. A., Rodgers, C. S., & Lebeck, M. M. (2010) · Journal of Child and Adolescent Psychiatric Nursing · doi:10.1111/j.1744-6171.2010.00229.x · Cited by 115 · see citing works
The potential of infant fMRI research and the study of early life stress as a promising exemplar
Graham, A. M., Pfeifer, J. H., Fisher, P. A., Lin, W., Gao, W., & Fair, D. A. (2015) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2014.09.005 · Cited by 114 · see citing works
Self-citationMaternal Childhood Maltreatment and Offspring Emotional and Behavioral Problems
Rijlaarsdam, J., Stevens, G. W. J. M., Jansen, P. W., Ringoot, A. P., Jaddoe, V. W. V., Albert Hofman, D., Ayer, L. A., Verhulst, F. C., Hudziak, J. J., & Tiemeier, H. W. (2014) · Child Maltreatment · doi:10.1177/1077559514527639 · Cited by 113 · see citing works
Bausenwein, J., Serke, H., Eberle, K., Hirrlinger, J., Jogschies, P., Hmeidan, F. A., Blumenauer, V., & Spanel‐Borowski, K. (2009) · Molecular Human Reproduction · doi:10.1093/molehr/gap078 · Cited by 110 · see citing works
Physiological markers of anxiety are increased in children of abused mothers
Jovanovic, T., Smith, A., Kamkwalala, A., Poole, J., Samples, T., Norrholm, S. D., Ressler, K. J., & Bradley, B. (2011) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2011.02410.x · Cited by 102 · see citing works
Buß, C., Entringer, S., Swanson, J. M., & Wadhwa, P. D. (2012) · Europe PMC (PubMed Central) · Cited by 91 · see citing works
Self-citationBublitz, M. H., & Stroud, L. R. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.01.009 · Cited by 88 · see citing works
Preconception Predictors of Weight Gain During Pregnancy
Weisman, C. S., Hillemeier, M. M., Downs, D. S., Chuang, C. H., & Dyer, A.-M. (2010) · Women s Health Issues · doi:10.1016/j.whi.2009.12.002 · Cited by 87 · see citing works
Wosu, A., Gelaye, B., & Williams, M. A. (2015) · Archives of Women's Mental Health · doi:10.1007/s00737-015-0533-0 · Cited by 82 · see citing works
Hillerer, K. M., Neumann, I. D., & Slattery, D. A. (2012) · Neuroendocrinology · doi:10.1159/000330445 · Cited by 82 · see citing works
Childhood abuse is associated with increased hair cortisol levels among urban pregnant women
Schreier, H. M. C., Enlow, M. B., Ritz, T., Gennings, C., & Wright, R. J. (2015) · Journal of Epidemiology & Community Health · doi:10.1136/jech-2015-205541 · Cited by 74 · see citing works
Maternal Childhood Abuse, Intimate Partner Violence, and Child Psychopathology
Miranda, J. K., de la Osa, N., Granero, R., & Ezpeleta, L. (2013) · Violence Against Women · doi:10.1177/1077801212475337 · Cited by 69 · see citing works
Maternal Exposure to the Holocaust and Health Complaints in Offspring
Flory, J. D., Bierer, L. M., & Yehuda, R. (2011) · Disease Markers · doi:10.1155/2011/250470 · Cited by 67 · see citing works
Moors, M., Bose, R., Johansson-Haque, K., Edoff, K., Okret, S., & Ceccatelli, S. (2011) · Toxicological Sciences · doi:10.1093/toxsci/kfr304 · Cited by 66 · see citing works
Mothers' violence victimization and child behavior problems: Examining the link.
Thompson, R. (2007) · American Journal of Orthopsychiatry · doi:10.1037/0002-9432.77.2.306 · Cited by 64 · see citing works
Endoplasmic Reticulum Stress Signaling in Mammalian Oocytes and Embryos: Life in Balance
Latham, K. E. (2015) · International review of cytology · doi:10.1016/bs.ircmb.2015.01.005 · Cited by 61 · see citing works
Bouvette–Turcot, A., Fleming, A. S., Wazana, A. D., Sokolowski, M. B., Gaudreau, H., González, A., Deslauriers, J., Kennedy, J. L., Steiner, M. S., & Meaney, M. J. (2015) · Genes Brain & Behavior · doi:10.1111/gbb.12205 · Cited by 60 · see citing works
Maternal childhood abuse predicts externalizing behaviour in toddlers: A prospective cohort study
Myhre, M. C., Dyb, G. A., Wentzel-Larsen, T., Grøgaard, J. B., & Thoresen, S. (2014) · Scandinavian Journal of Public Health · doi:10.1177/1403494813510983 · Cited by 57 · see citing works
Wieck, A., Grassi‐Oliveira, R., do Prado, C. H., Teixeira, A. L., & Bauer, M. E. (2014) · NeuroImmunoModulation · doi:10.1159/000356552 · Cited by 52 · see citing works
Zhou, P., Lian, H.-Y., Cui, W., Wei, D.-L., Li, Q., Liu, Y.-X., Liu, X., & Tan, J. (2011) · Biology of Reproduction · doi:10.1095/biolreprod.111.095281 · Cited by 49 · see citing works
Gelaye, B., Kajeepeta, S., Zhong, Q., Borba, C. P. C., Rondón, M. B., Sánchez, S. E., Henderson, D. C., & Williams, M. A. (2015) · Sleep Medicine · doi:10.1016/j.sleep.2015.07.004 · Cited by 45 · see citing works
Transgenerational Epigenetic Inheritance in Animals
Kovalchuk, I. (2012) · Frontiers in Genetics · doi:10.3389/fgene.2012.00076 · Cited by 44 · see citing works
Women’s Experience of Abuse in Childhood and Their Children’s Smoking and Overweight
Roberts, A. L., Galea, S., Austin, S. B., Corliss, H. L., Williams, M. A., & Koenen, K. C. (2014) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2013.11.012 · Cited by 39 · see citing works
The association between early life adversity and bacterial vaginosis during pregnancy
Cammack, A. L., Buß, C., Entringer, S., HOGUE, C. J. R., Hobel, C. J., & Wadhwa, P. D. (2011) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2011.01.054 · Cited by 39 · see citing works
Self-citationBublitz, M. H., Parade, S. H., & Stroud, L. R. (2014) · Biological Psychology · doi:10.1016/j.biopsycho.2014.08.014 · Cited by 38 · see citing works
Bublitz, M. H., & Stroud, L. R. (2013) · Stress · doi:10.3109/10253890.2013.825768 · Cited by 32 · see citing works
Child maltreatment and obesity over the life-course: A 40-year cohort study
Danese, A. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.07.475 · Cited by 1 · see citing works
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Intergenerational transmission of trauma effects: putative role of epigenetic mechanisms
Yehuda, R., & Lehrner, A. (2018) · World Psychiatry · doi:10.1002/wps.20568 · Cited by 730 · see citing works
A Meta-Analysis of Maternal Prenatal Depression and Anxiety on Child Socioemotional Development
Madigan, S. L., Oatley, H., Racine, N. M., Fearon, P. R. M., Schumacher, L., Akbari, E. M., Cooke, J. E., & Tarabulsy, G. M. (2018) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2018.06.012 · Cited by 456 · see citing works
Life Course Approaches to the Causes of Health Disparities
Jones, N. L., Gilman, S. E., Cheng, T. L., Drury, S. S., Hill, C. V., & Geronimus, A. T. (2019) · American Journal of Public Health · doi:10.2105/ajph.2018.304738 · Cited by 414 · see citing works
Rudolph, M. D., Graham, A. M., Feczko, E., Miranda-Dominguez, O., Rasmussen, J. M., Nardos, R., Entringer, S., Wadhwa, P. D., Buss, C., & Fair, D. A. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0128-y · Cited by 374 · see citing works
Self-citationPregnancy as a period of risk, adaptation, and resilience for mothers and infants
Davis, E. P., & Narayan, A. J. (2020) · Development and Psychopathology · doi:10.1017/s0954579420001121 · Cited by 297 · see citing works
“Further, childhood maltreatment also is associated with alterations in placental–fetal stress physiology, including significantly steeper increases in placental CRH across gestation (Buss et al., 2017; Moog et al., 2018).”
BackgroundMaternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes
Walsh, K., McCormack, C. A., Webster, R., Pinto, A., Lee, S., Feng, T., Krakovsky, H. S., O’Grady, S. M., Tycko, B., Champagne, F. A., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1905890116 · Cited by 258 · see citing works
Cooke, J. E., Racine, N. M., Plamondon, A., Tough, S., & Madigan, S. L. (2019) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2019.04.011 · Cited by 259 · see citing works
Maternal Adverse Childhood Experiences and Infant Development
Racine, N. M., Plamondon, A., Madigan, S. L., McDonald, S., & Tough, S. (2018) · PEDIATRICS · doi:10.1542/peds.2017-2495 · Cited by 240 · see citing works
Graham, A. M., Rasmussen, J. M., Entringer, S., Ben Ward, E., Rudolph, M. D., Gilmore, J. H., Styner, M., Wadhwa, P. D., Fair, D. A., & Buss, C. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.06.023 · Cited by 203 · see citing works
Self-citationAdverse childhood experiences and maternal anxiety and depression: a meta-analysis
Racine, N. M., Devereaux, C., Cooke, J. E., Eirich, R., Zhu, J., & Madigan, S. L. (2021) · BMC Psychiatry · doi:10.1186/s12888-020-03017-w · Cited by 197 · see citing works
The fetal programming of telomere biology hypothesis: an update
Entringer, S., de Punder, K., Buß, C., & Wadhwa, P. D. (2018) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2017.0151 · Cited by 189 · see citing works
Self-citationIntergenerational Effect of Maternal Exposure to Childhood Maltreatment on Newborn Brain Anatomy
Moog, N. K., Entringer, S., Rasmussen, J. M., Styner, M., Gilmore, J. H., Kathmann, N., Heim, C. M., Wadhwa, P. D., & Buss, C. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.07.009 · Cited by 189 · see citing works
Self-citationKimber, M., Adham, S., Gill, S., McTavish, J., & MacMillan, H. L. (2018) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2017.11.007 · Cited by 182 · see citing works
Atzl, V. M., Narayan, A. J., Rivera, L. M., & Lieberman, A. F. (2019) · Journal of Family Psychology · doi:10.1037/fam0000510 · Cited by 162 · see citing works
Heim, C. M., Entringer, S., & Buss, C. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.12.011 · Cited by 158 · see citing works
Self-citationDean, D. C., Planalp, E. M., Wooten, W., Kecskemeti, S. R., Adluru, N., Schmidt, C. K., Frye, C., Birn, R. M., Burghy, C. A., Schmidt, N. L., et al. (2018) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2018.2132 · Cited by 138 · see citing works
Scorza, P., Duarte, C. S., Hipwell, A. E., Posner, J. E., Ortin‐Peralta, A., CANINO, G. J., Monk, C. E., & Outcomes, P. C. F. E. I. O. C. H. (2018) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12877 · Cited by 135 · see citing works
Lindsay, K. L., Buß, C., Wadhwa, P. D., & Entringer, S. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.06.021 · Cited by 135 · see citing works
Self-citationSchepanski, S. N., Buß, C., Hanganu‐Opatz, I. L., & Arck, P. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02186 · Cited by 129 · see citing works
Sex differences in functional connectivity during fetal brain development
Wheelock, M. D., Hect, J. L., Hernandez-Andrade, E., Hassan, S. S., Romero, R., Eggebrecht, A. T., & Thomason, M. E. (2019) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2019.100632 · Cited by 126 · see citing works
McDonald, S., Madigan, S. L., Racine, N. M., Benzies, K., Tomfohr‐Madsen, L. M., & Tough, S. (2018) · Preventive Medicine · doi:10.1016/j.ypmed.2018.11.013 · Cited by 120 · see citing works
Berthelot, N., Lemieux, R., Garon‐Bissonnette, J., Lacharité, C., & Muzik, M. (2019) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2019.104065 · Cited by 112 · see citing works
Mechanisms of neuroplasticity linking early adversity to depression: developmental considerations
Ho, T. C., & King, L. S. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01639-6 · Cited by 108 · see citing works
Adverse childhood experiences and intimate partner violence: A meta-analysis
Zhu, J., Exner‐Cortens, D., Dobson, K. S., Wells, L., Noel, M. E., & Madigan, S. L. (2023) · Development and Psychopathology · doi:10.1017/s0954579423000196 · Cited by 100 · see citing works
Moog, N. K., Cummings, P., Jackson, K., Aschner, J. L., Barrett, E. S., Bastain, T. M., Blackwell, C. K., Enlow, M. B., Breton, C. V., Bush, N. R., et al. (2023) · The Lancet Public Health · doi:10.1016/s2468-2667(23)00025-7 · Cited by 91 · see citing works
Self-citationSchmidt, M. R., Narayan, A. J., Atzl, V. M., Rivera, L. M., & Lieberman, A. F. (2018) · Journal of Aggression Maltreatment & Trauma · doi:10.1080/10926771.2018.1524806 · Cited by 90 · see citing works
Pfaltz, M. C., Halligan, S. L., Haim‐Nachum, S., Sopp, M. R., Åhs, F., Bachem, R., Bartoli, E., Belete, H., Mossie, T. B., Berzengi, A., et al. (2022) · Psychotherapy and Psychosomatics · doi:10.1159/000523667 · Cited by 92 · see citing works
Dissecting early life stress-induced adolescent depression through epigenomic approach
Ochi, S., & Dwivedi, Y. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01907-x · Cited by 90 · see citing works
Could epigenetics help explain racial disparities in chronic pain?
Aroke, E. N., Joseph, P. V., Roy, A., Overstreet, D. S., Tollefsbol, T. O., Vance, D. E., & Goodin, B. R. (2019) · Journal of Pain Research · doi:10.2147/jpr.s191848 · Cited by 84 · see citing works
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Cooke, J. E., Racine, N. M., Pador, P., & Madigan, S. L. (2021) · PEDIATRICS · doi:10.1542/peds.2020-044131 · Cited by 89 · see citing works
Pohl, T. T., Young, L. J., & Bosch, O. J. (2019) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2017.12.011 · Cited by 83 · see citing works
Maternal Childhood Adversity Associates With Frontoamygdala Connectivity in Neonates
Hendrix, C. L., Dilks, D. D., McKenna, B. G., Dunlop, A. L., Corwin, E. J., & Brennan, P. A. (2020) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2020.11.003 · Cited by 78 · see citing works
Su, Y., D’Arcy, C., & Meng, X. (2020) · Trauma Violence & Abuse · doi:10.1177/1524838020933870 · Cited by 76 · see citing works
Cruceanu, C., Dony, L., Krontira, A. C., Fischer, D. S., Roeh, S., Giaimo, R. D., Kyrousi, C., Kaspar, L., Arloth, J., Czamara, D., et al. (2021) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2021.21010095 · Cited by 70 · see citing works
How stress can influence brain adaptations to motherhood
Kim, P. (2020) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2020.100875 · Cited by 73 · see citing works
Kress, V., Steudte‐Schmiedgen, S., Kopp, M., Förster, A., Altus, C., Schier, C., Wimberger, P., Kirschbaum, C., von Soest, T., Weidner, K., et al. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.01273 · Cited by 66 · see citing works
Gray, S. A. O., Jones, C. W., Theall, K. P., Glackin, E. B., & Drury, S. S. (2017) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2017.09.001 · Cited by 67 · see citing works
Wiss, D. A., Avena, N., & Gold, M. (2020) · Nutrients · doi:10.3390/nu12113521 · Cited by 66 · see citing works
Seah, C., Breen, M. S., Rusielewicz, T., Bader, H. N., Xu, C., Hunter, C. J., McCarthy, B., Deans, P. J. M., Chattopadhyay, M., Goldberg, J., et al. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01161-y · Cited by 67 · see citing works
Bhushan, D., Kotz, K. J., McCall, J., Wirtz, S., Gilgoff, R., Dube, S. R., Powers, C., Olson-Morgan, J., Galeste, M., Patterson, K., et al. (2020) · doi:10.48019/peam8812 · Cited by 71 · see citing works
Christie, H., Talmon, A., Schäfer, S. K., de Haan, A., Vang, M. L., Haag, K., Gilbar, O., Alisic, E., & Brown, E. A. (2017) · European Journal of Psychotraumatology · doi:10.1080/20008198.2018.1492834 · Cited by 62 · see citing works
Associations between adverse childhood experiences and substance use: A meta-analysis
Zhu, J., Racine, N. M., Devereux, C., Hodgins, D. C., & Madigan, S. L. (2023) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2023.106431 · Cited by 63 · see citing works
Adverse childhood experiences and HPA axis function in pregnant women
Thomas, J. C., Magel, C. A., Tomfohr‐Madsen, L. M., Madigan, S. L., Letourneau, N. L., Campbell, T. S., & Giesbrecht, G. F. (2018) · Hormones and Behavior · doi:10.1016/j.yhbeh.2018.04.004 · Cited by 56 · see citing works
Psychosocial Stress and Adversity: Effects from the Perinatal Period to Adulthood
Barrero‐Castillero, A., Morton, S. U., Nelson, C. A., & Smith, V. C. (2019) · NeoReviews · doi:10.1542/neo.20-12-e686 · Cited by 55 · see citing works
Swales, D. A., Stout, S. A., Glynn, L. M., Sandman, C. A., Wing, D. A., & Davis, E. P. (2018) · Biological Psychology · doi:10.1016/j.biopsycho.2018.10.006 · Cited by 54 · see citing works
Pregnancy-Related Extracellular Vesicles Revisited
Condrat, C. E., Varlas, V. N., Duică, F., Antoniadis, P., Dănilă, C. A., Crețoiu, D., Suciu, N., Creţoiu, S. M., & Voinea, S. C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22083904 · Cited by 54 · see citing works
Garon‐Bissonnette, J., Duguay, G., Lemieux, R., Dubois‐Comtois, K., & Berthelot, N. (2021) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2021.105030 · Cited by 49 · see citing works
Prenatal Maternal Stress Causes Preterm Birth and Affects Neonatal Adaptive Immunity in Mice
Garcia‐Flores, V., Romero, R. J., Furcron, A.-E., Levenson, D., Galaz, J., Zou, C., Hassan, S. S., Hsu, C., Olson, D. M., Metz, G. A. S., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00254 · Cited by 49 · see citing works
Querdasi, F. R., Enders, C. K., Karnani, N., Broekman, B. F. P., Seng, C. Y., Gluckman, P. D., Daniel, L. M., Yap, F. K. P., Eriksson, J. G., Cai, S., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2213768120 · Cited by 45 · see citing works
Thomason, M. E., Palopoli, A. C., Jariwala, N. N., Werchan, D. M., Chen, A., Adhikari, S., Espinoza‐Heredia, C., Brito, N. H., & Trentacosta, C. J. (2021) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2021.101000 · Cited by 42 · see citing works
Childhood Trauma and Sleep Among Young Adults With a History of Depression: A Daily Diary Study
Hamilton, J. L., Brindle, R. C., Alloy, L. B., & Liu, R. T. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00673 · Cited by 43 · see citing works
Maternal Perinatal Stress Trajectories and Negative Affect and Amygdala Development in Offspring
Marr, M. C., Graham, A. M., Feczko, E., Nolvi, S., Thomas, E., Sturgeon, D., Schifsky, E., Rasmussen, J. M., Gilmore, J. H., Styner, M. A., et al. (2023) · American Journal of Psychiatry · doi:10.1176/appi.ajp.21111176 · Cited by 40 · see citing works
Self-citationLazarides, C., Ward, E. B., Buß, C., Chen, W., Voelkle, M. C., Gillen, D. L., Wadhwa, P. D., & Entringer, S. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.104848 · Cited by 39 · see citing works
Self-citationOosterman, M., Schuengel, C., Forrer, M. L., & De Moor, M. H. M. (2019) · Development and Psychopathology · doi:10.1017/s0954579418001591 · Cited by 38 · see citing works
Prenatal PFAS exposure, gut microbiota dysbiosis, and neurobehavioral development in childhood
Zhou, Y., Zhang, L., Li, Q., Wang, H., Wang, H., Shi, H., Lu, W., & Zhang, Y. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.133920 · Cited by 38 · see citing works
Perinatal promotive and protective factors for women with histories of childhood abuse and neglect
Atzl, V. M., Grande, L. A., Davis, E. P., & Narayan, A. J. (2019) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2019.02.008 · Cited by 33 · see citing works
Li, C., Fu, P., Wang, M., Xia, Y., Hu, C., Liu, M., Zhang, H., Sheng, X., & Yang, Y. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-04719-7 · Cited by 37 · see citing works
Chang, Y., Feng, J., Chang, H., Chang, Y. W., & Lee, C. (2020) · Development and Psychopathology · doi:10.1017/s0954579420000267 · Cited by 32 · see citing works
McCormack, C. A., Lauriola, V., Feng, T., Lee, S., Spann, M. N., Mitchell, A., Champagne, F. A., & Monk, C. E. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.09.023 · Cited by 30 · see citing works
Babineau, V., Fonge, Y. N., Miller, E. S., Grobman, W. A., Ferguson, P. L., Hunt, K. J., Vena, J. E., Newman, R., Guille, C., Tita, A., et al. (2022) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2022.03.021 · Cited by 31 · see citing works
On the role of epigenetic modifications of HPA axis in posttraumatic stress disorder and resilience
Khan, Z., Messiri, N. E., Iqbal, E., Hassan, H., Tanweer, M. S., Sadia, S. R., Taj, M., Zaidi, U., Yusuf, K., Syed, N. I., et al. (2025) · Journal of Neurophysiology · doi:10.1152/jn.00345.2024 · Cited by 32 · see citing works
Luo, S.-Y., Chen, D., Li, C.-R., Lin, L., Chen, W.-Q., Ren, Y., Zhang, Y., Xing, F., & Guo, V. (2023) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/s13034-023-00646-3 · Cited by 31 · see citing works
Maternal Interleukin-6 Is Associated With Macaque Offspring Amygdala Development and Behavior
Ramirez, J. S. B., Graham, A. M., Thompson, J. R., Zhu, J. Y., Sturgeon, D., Bagley, J. L., Thomas, E., Papadakis, S., Bah, M., Perrone, A. J., et al. (2019) · Cerebral Cortex · doi:10.1093/cercor/bhz188 · Cited by 29 · see citing works
Self-citationStargel, L. E., & Easterbrooks, M. A. (2020) · Social Science & Medicine · doi:10.1016/j.socscimed.2020.112828 · Cited by 29 · see citing works
Kleih, T. S., Entringer, S., Scholaske, L., Kathmann, N., de Punder, K., Heim, C. C., Wadhwa, P. D., & Buß, C. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2022.02.004 · Cited by 30 · see citing works
Self-citationMaternal adverse childhood experiences and infant subcortical brain volume
Demers, C. H., Hankin, B. L., Hennessey, E. P., Haase, M. H., Bagonis, M. M., Kim, S. H., Gilmore, J. H., Hoffman, M. C., Styner, M. A., & Davis, E. P. (2022) · Neurobiology of Stress · doi:10.1016/j.ynstr.2022.100487 · Cited by 29 · see citing works
Pittner, K., van IJzendoorn, M. H., Alink, L. R. A., Buisman, R. S. M., Block, L. C.-D., van den Berg, L. J. M., Elzinga, B. M., Lindenberg, J., Tollenaar, M. S., Diego, V. P., et al. (2019) · Development and Psychopathology · doi:10.1017/s0954579418001608 · Cited by 28 · see citing works
Maternal Childhood Adversity as a Risk for Perinatal Complications and NICU Hospitalization
Ciciolla, L. M., Shreffler, K. M., & Tiemeyer, S. M. (2021) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsab027 · Cited by 28 · see citing works
Sanders, A. F. P., Tirado, B. A., Seider, N. A., Triplett, R. L., Lean, R. E., Neil, J. J., Miller, J. P., Tillman, R., Smyser, T. A., Barch, D. M., et al. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02782-6 · Cited by 27 · see citing works
Babineau, V., McCormack, C. A., Feng, T., Lee, S., Berry, O. O., Knight, B. T., Newport, D. J., Stowe, Z. N., & Monk, C. E. (2022) · Bipolar Disorders · doi:10.1111/bdi.13207 · Cited by 26 · see citing works
Enlow, M. B., Petty, C. R., Svelnys, C., Gusman, M. S., Garcia, M. H., Malin, A. J., & Wright, R. J. (2019) · Developmental Neuropsychology · doi:10.1080/87565641.2019.1611833 · Cited by 26 · see citing works
Kern, A., Khoury, B., Frederickson, A., & Langevin, R. (2022) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2022.110985 · Cited by 26 · see citing works
Lyons‐Ruth, K., Li, F. H., Khoury, J. E., Ahtam, B., Sisitsky, M. D., Ou, Y., Enlow, M. B., & Grant, P. E. (2023) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-023-01041-4 · Cited by 30 · see citing works
van den Heuvel, M. I., Monk, C. E., Hendrix, C. L., Hect, J. L., Lee, S., Feng, T., & Thomason, M. E. (2023) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2023.03.020 · Cited by 26 · see citing works
Racine, N. M., McDonald, S., Chaput, K. H., Tough, S., & Madigan, S. L. (2021) · Journal of Women s Health · doi:10.1089/jwh.2020.8632 · Cited by 25 · see citing works
Khoury, J. E., Ahtam, B., Sisitsky, M. D., Ou, Y., Gagoski, B. A., Enlow, M. B., Teicher, M. H., Grant, P. E., & Lyons‐Ruth, K. (2021) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2021.09.005 · Cited by 26 · see citing works
Ortiz, R. (2019) · American Journal of Lifestyle Medicine · doi:10.1177/1559827619839997 · Cited by 25 · see citing works
Khoury, J. E., Beeney, J. E., Shiff, I., Enlow, M. B., & Lyons‐Ruth, K. (2021) · Developmental Psychobiology · doi:10.1002/dev.22109 · Cited by 25 · see citing works
Fraiman, Y. S., Barrero‐Castillero, A., & Litt, J. S. (2022) · Seminars in Perinatology · doi:10.1016/j.semperi.2022.151660 · Cited by 24 · see citing works
Racine, N. M., Ereyi-Osas, W., Killam, T., McDonald, S., & Madigan, S. L. (2021) · Children · doi:10.3390/children8111061 · Cited by 23 · see citing works
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Keverne, J., & Binder, E. B. (2020) · Medizinische Genetik · doi:10.1515/medgen-2020-2004 · Cited by 24 · see citing works
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Leal, A. S. M., Silvers, J. A., Carroll, J., Cole, S. W., Ross, K. M., Ramey, S. L., Shalowitz, M. U., & Schetter, C. D. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2022.10.012 · Cited by 23 · see citing works
Wakschlag, L. S., Tandon, D., Krogh‐Jespersen, S., Petitclerc, A., Nielsen, A., Ghaffari, R., Mithal, L., Bass, M., Ward, E., Berken, J., et al. (2021) · Developmental Psychobiology · doi:10.1002/dev.22057 · Cited by 21 · see citing works
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Ciciolla, L. M., Addante, S., Quigley, A. N., Erato, G., & Fields, K. (2021) · Infant Behavior and Development · doi:10.1016/j.infbeh.2021.101664 · Cited by 21 · see citing works
Hendrix, C. L., Brown, A. L., McKenna, B. G., Dunlop, A. L., Corwin, E. J., & Brennan, P. A. (2022) · Journal of Psychopathology and Clinical Science · doi:10.1037/abn0000688 · Cited by 21 · see citing works
Töpfer, P., O’Donnell, K. J., Entringer, S., Heim, C. C., Lin, D. T. S., MacIsaac, J. L., Kobor, M. S., Meaney, M. J., Provençal, N., Binder, E. B., et al. (2019) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2019.03.006 · Cited by 20 · see citing works
Self-citationBerthelot, N., Drouin‐Maziade, C., Garon‐Bissonnette, J., Lemieux, R., Sériès, T., & Lacharité, C. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.772706 · Cited by 20 · see citing works
Swales, D. A., Davis, E. P., Mahrer, N. E., Guardino, C. M., Shalowitz, M. U., Ramey, S. L., & Schetter, C. D. (2022) · Development and Psychopathology · doi:10.1017/s0954579421001760 · Cited by 20 · see citing works
Zhao, T., Alder, N. N., Starkweather, A. R., Chen, M., Matson, A. P., Xu, W., Balsbaugh, J. L., & Cong, X. S. (2022) · Developmental Neuroscience · doi:10.1159/000526491 · Cited by 19 · see citing works
Tu, H., Skalkidou, A., Lindskog, M., & Gredebäck, G. (2021) · Scientific Reports · doi:10.1038/s41598-021-03568-2 · Cited by 19 · see citing works
Penner, F., Khoury, J. E., Enlow, M. B., & Lyons‐Ruth, K. (2023) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2023.106107 · Cited by 19 · see citing works
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Keenan‐Devlin, L. S., Borders, A. E. B., Freedman, A. A., Miller, G. E., Grobman, W. A., Entringer, S., Simhan, H. N., Wadhwa, P. D., & Buß, C. (2023) · Scientific Reports · doi:10.1038/s41598-023-36831-9 · Cited by 18 · see citing works
Self-citationHoluka, C., Grova, N., Charalambous, E. G., Cléac`H, J. L., Turner, J. D., & Mposhi, A. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105785 · Cited by 18 · see citing works
Berthelot, N., Lemieux, R., & Lacharité, C. (2018) · Health Promotion and Chronic Disease Prevention in Canada · doi:10.24095/hpcdp.38.11.01 · Cited by 19 · see citing works
Expanding our understanding of intergenerational exposure to adversity
Negriff, S. L. (2020) · Children and Youth Services Review · doi:10.1016/j.childyouth.2020.105369 · Cited by 17 · see citing works
Bravo, P., Kim, Y., Xerxa, Y., Koopman‐Verhoeff, M. E., Cárcamo, R. A., Oldehinkel, A. J., Hillegers, M. H. J., & Jansen, P. W. (2023) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2023.106228 · Cited by 17 · see citing works
Giallo, R., Gartland, D., Seymour, M., Conway, L. J., Mensah, F. K., Skinner, L., Fogarty, A., & Brown, S. (2019) · Journal of Family Psychology · doi:10.1037/fam0000623 · Cited by 19 · see citing works
Lindsay, K. L., Entringer, S., Buß, C., & Wadhwa, P. D. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.104659 · Cited by 17 · see citing works
Self-citationScorza, P., Duarte, C. S., Lee, S., Wu, H., Posner, J., Baccarelli, A., & Monk, C. (2023) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2023.02.018 · Cited by 18 · see citing works
Intergenerational Effects of Racism
Lugo-Candelas, C. I., Polanco-Roman, L. A., & Duarte, C. S. (2021) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2021.1852 · Cited by 16 · see citing works
- Authors
- Buss, C., Entringer, S., Moog, N. K., Toepfer, P., Fair, D. A., Simhan, H. N., Heim, C. M., & Wadhwa, P. D.
- Affiliations
- University of California, Irvine (US)
- Humboldt-Universität zu Berlin (DE)
- Oregon Health & Science University (US)
- University of Pittsburgh (US)
- Corresponding author
- Buss, Claudia
- Venue
- Journal of the American Academy of Child & Adolescent Psychiatry
- Publisher
- Elsevier BV
- Published
- 2017-05
- Volume
- 56
- Issue
- 5
- Pages
- 373-382
- ISSN
- 0890-8567 (ISSN-L)
- PMC
- PMC5402756
- OpenAlex
- W2593056494
- Cited by
- 250
- References
- 118
- Citations by year
- 2026: 10 · 2025: 38 · 2024: 24 · 2023: 36 · 2022: 35 · 2021: 32 · 2020: 25 · 2019: 22 · 2018: 23 · 2017: 5
- FWCI
- 3.14
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institute of Mental Health (R01MH091351, R01MH105538)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD060628)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Keywords
- child abuse, intergenerational transmission, maternal childhood maltreatment, fetal brain development, biological embedding, placenta, maternal stress, maternal immune activation, endocrine pathways, prenatal stress exposure, developmental origins of health and disease
- MeSH terms
- Brain, Child, Child Abuse, Child Development, Female, Humans, Mothers, Pregnancy, Prenatal Exposure Delayed Effects, Risk Factors, Stress, Psychological, Fetal Development
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