Cited by 363Hormonal and reproductive studiesAdrenal Hormones and DisordersMenopause: Health Impacts and Treatments

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Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline

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Wierman, Margaret E., Arlt, Wiebke, Basson, Rosemary, Davis, Susan R., Miller, Karen K., Murad, Mohammad H., Rosner, William, Santoro, Nanette·2014·The Journal of Clinical Endocrinology & Metabolism

DOI 10.1210/jc.2014-2260

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Abstract

OBJECTIVE: To update practice guidelines for the therapeutic use of androgens in women. PARTICIPANTS: A Task Force appointed by the Endocrine Society, American Congress of Obestricians and Gynecologists (ACOG), American Society for Reproductive Medicine (ASRM), European Society of Endocrinology (ESE), and International Menopause Society (IMS) consisting of six experts, a methodologist, and a medical writer. EVIDENCE: The Task Force commissioned two systematic reviews of published data and considered several other existing meta-analyses and trials. The GRADE methodology was used; the strength of a recommendation is indicated by a number "1" (strong recommendation, we recommend) or "2" (weak recommendation, we suggest). CONSENSUS PROCESS: Multiple e-mail communications and conference calls determined consensus. Committees of the Endocrine Society, ASRM, ACOG, ESE, and IMS reviewed and commented on the drafts of the guidelines. CONCLUSIONS: We continue to recommend against making a diagnosis of androgen deficiency syndrome in healthy women because there is a lack of a well-defined syndrome, and data correlating androgen levels with specific signs or symptoms are unavailable. We recommend against the general use of T for the following indications: infertility; sexual dysfunction other than hypoactive sexual desire disorder; cognitive, cardiovascular, metabolic, or bone health; or general well-being. We recommend against the routine use of dehydroepiandrosterone due to limited data concerning its effectiveness and safety in normal women or those with adrenal insufficiency. We recommend against the routine prescription of T or dehydroepiandrosterone for the treatment of women with low androgen levels due to hypopituitarism, adrenal insufficiency, surgical menopause, pharmacological glucocorticoid administration, or other conditions associated with low androgen levels because there are limited data supporting improvement in signs and symptoms with therapy and no long-term studies of risk. Evidence supports the short-term efficacy and safety of high physiological doses of T treatment of postmenopausal women with sexual dysfunction due to hypoactive sexual desire disorder. Importantly, endogenous T levels did not predict response to therapy. At present, physiological T preparations for use in women are not available in many countries including the United States, and long-term safety data are lacking. We recommend that any woman receiving T therapy be monitored for signs and symptoms of androgen excess. We outline areas for future research. Ongoing improvement in androgen assays will allow a redefinition of normal ranges across the lifespan; this may help to clarify the impact of varying concentrations of plasma androgens on the biology, physiology, and psychology in women and lead to indications for therapeutic interventions.

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1 retracted

Withdrawn: Postmenopausal Women with a History of Irregular Menses and Elevated Androgen Measurements at High Risk for Worsening Cardiovascular Event-Free Survival: Results from the National Institutes of Health—National Heart, Lung, and Blood Institute Sponsored Women’s Ischemia Syndrome Evaluation
Shaw, L. J., Bairey Merz, C. N., Azziz, R., Stanczyk, F. Z., Sopko, G., Braunstein, G. D., Kelsey, S. F., Kip, K. E., Cooper-DeHoff, R. M., Johnson, B. D., et al. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0425 · Cited by 427
Retracted
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,842
Grading quality of evidence and strength of recommendations
(2004) · BMJ · doi:10.1136/bmj.328.7454.1490 · Cited by 8,477
GRADE guidelines: 3. Rating the quality of evidence
Balshem, H., Helfand, M., Schünemann, H. J., Oxman, A. D., Kunz, R., Brozek, J., Vist, G. E., Falck-Ytter, Y., Meerpohl, J., & Norris, S. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.07.015 · Cited by 8,285
A Critical Evaluation of Simple Methods for the Estimation of Free Testosterone in Serum
Vermeulen, A., Verdonck, L., & Kaufman, J. M. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.10.6079 · Cited by 3,824
Endogenous Sex Hormones and Breast Cancer in Postmenopausal Women: Reanalysis of Nine Prospective Studies
The Endogenous Hormones and Breast Cancer Collaborative Group (2002) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/94.8.606 · Cited by 1,799
Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood
ORENTREICH, N., BRIND, J. L., RIZER, R. L., & VOGELMAN, J. H. (1984) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-59-3-551 · Cited by 1,349
Systems for grading the quality of evidence and the strength of recommendations I: Critical appraisal of existing approaches The GRADE Working Group
Atkins, D., Eccles, M., Flottorp, S., Guyatt, G. H., Henry, D., Hill, S., Liberati, A., O'Connell, D., Oxman, A. D., Phillips, B., et al. (2004) · BMC Health Services Research · doi:10.1186/1472-6963-4-38 · Cited by 1,235
Sex‐hormone binding-globulin
ANDERSON, D. C. (1974) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1974.tb03298.x · Cited by 1,127
Calculation of free and bound fractions of testosterone and estradiol-17β to human plasma proteins at body temperature
Södergard, R., Bäckström, T., Shanbhag, V., & Carstensen, H. (1982) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(82)90038-3 · Cited by 1,080
Androgen Levels in Adult Females: Changes with Age, Menopause, and Oophorectomy
Davison, S. L., Bell, R., Donath, S., Montalto, J. G., & Davis, S. R. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0212 · Cited by 998
Self-citation
Transdermal testosterone treatment in women with impaired sexual function after oophorectomy.
Shifren, J. L., Braunstein, G. D., Simon, J. A., Casson, P. R., Buster, J. E., Redmond, G. P., Burki, R. E., Ginsburg, E. S., Rosen, R. C., Leiblum, S. R., et al. (2000) · New England Journal of Medicine · doi:10.1056/nejm200009073431002 · Cited by 954
Why Humans Have Sex
Meston, C. M., & Buss, D. M. (2007) · Archives of Sexual Behavior · doi:10.1007/s10508-007-9175-2 · Cited by 781
Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men
Falahati-Nini, A., Riggs, B. L., Atkinson, E. J., O’Fallon, W. M., Eastell, R., & Khosla, S. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10942 · Cited by 757
Sex hormone-binding globulin and risk of type 2 diabetes in women and men
Ding, E. L., Song, Y., Manson, J. E., Hunter, D. J., Lee, C. C., Rifai, N., Buring, J. E., Gaziano, J. M., & Liu, S. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0804381 · Cited by 726
Androgens stimulate early stages of follicular growth in the primate ovary
Vendola, K. A., Zhou, J., Adesanya, O. O., Weil, S. J., & Bondy, C. A. (1998) · Journal of Clinical Investigation · doi:10.1172/jci2081 · Cited by 712
Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination
Furman, D., Hejblum, B. P., Simon, N., Jojic, V., Dekker, C. L., Thiébaut, R., Tibshirani, R. J., & Davis, M. M. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321060111 · Cited by 700
Dehydroepiandrosterone Replacement in Women with Adrenal Insufficiency
Arlt, W., Callies, F., van Vlijmen, J. C., Koehler, I., Reincke, M., Bidlingmaier, M., Huebler, D., Oettel, M., Ernst, M., Schulte, H. M., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909303411401 · Cited by 644
Self-citation
Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue.
Baulieu, E.-E., Thomas, G., Legrain, S., Lahlou, N., Roger, M., Debuire, B., Faucounau, V., Girard, L., Hervy, M.-P., Latour, F., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.8.4279 · Cited by 577
DHEA in elderly women and DHEA or testosterone in elderly men.
Nair, K. S., Rizza, R. A., O'Brien, P., Dhatariya, K., Short, K. R., Nehra, A., Vittone, J. L., Klee, G. G., Basu, A., Basu, R., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa054629 · Cited by 566
Protective actions of sex steroid hormones in Alzheimer’s disease
Pike, C. J., Carroll, J. C., Rosario, E. R., & Barron, A. M. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.04.015 · Cited by 541
Testosterone enhances estradiol's effects on postmenopausal bone density and sexuality
Davis, S. R., McCloud, P., Strauss, B. J., & Burger, H. (1995) · Maturitas · doi:10.1016/0378-5122(94)00898-h · Cited by 534
Self-citation
Postmenopausal serum androgens, oestrogens and breast cancer risk: the European prospective investigation into cancer and nutrition
Kaaks, R., Rinaldi, S., Key, T. J., Berrino, F., Peeters, P. H. M., Biessy, C., Dossus, L., Lukanova, A., Bingham, S. A., Khaw, K., et al. (2005) · Endocrine Related Cancer · doi:10.1677/erc.1.01038 · Cited by 532
Endogenous Estrogen, Androgen, and Progesterone Concentrations and Breast Cancer Risk Among Postmenopausal Women
Missmer, S. A., Eliassen, A. H., Barbieri, R. L., & Hankinson, S. E. (2004) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djh336 · Cited by 516
Endocrine function of the postmenopausal ovary: concentration of androgens and estrogens in ovarian and peripheral vein blood.
JUDD, H. L., JUDD, G. E., LUCAS, W. E., & YEN, S. S. C. (1974) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-39-6-1020 · Cited by 511 · cited 2×
“Total and free T decline progressively with reproductive aging (14–21).”
Testosterone for Low Libido in Postmenopausal Women Not Taking Estrogen
Davis, S. R., Moreau, M., Kroll, R., Bouchard, C., Panay, N., Gass, M. L. S., Braunstein, G. D., Hirschberg, A. L., Rodenberg, C. A., Pack, S. E., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0707302 · Cited by 490
Self-citation
Testosterone patch increases sexual activity and desire in surgically menopausal women with hypoactive sexual desire disorder.
Simon, J., Braunstein, G., Nachtigall, L., Utian, W., Katz, M., Miller, S., Waldbaum, A., Bouchard, C., Derzko, C., Buch, A., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1747 · Cited by 475
Self-citation
Safety and Efficacy of a Testosterone Patch for the Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women: A Randomized, Placebo-Controlled Trial
Braunstein, G. D., Sundwall, D. A., Katz, M., Shifren, J. L., Buster, J. E., Simon, J. A., Bachman, G., Aguirre, O. A., Lucas, J. D., Rodenberg, C., et al. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.14.1582 · Cited by 458
Hypoactive sexual desire disorder in postmenopausal women: US results from the Women's International Study of Health and Sexuality (WISHeS)
Leiblum, S. R., Koochaki, P. E., Rodenberg, C. A., Barton, I. P., & Rosen, R. C. (2006) · Menopause The Journal of The North American Menopause Society · doi:10.1097/01.gme.0000172596.76272.06 · Cited by 446
A Prospective Longitudinal Study of Serum Testosterone, Dehydroepiandrosterone Sulfate, and Sex Hormone-Binding Globulin Levels through the Menopause Transition1
Burger, H. G., Dudley, E. C., Cui, J., Dennerstein, L., & Hopper, J. L. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.8.6740 · Cited by 439
Testosterone patch for low sexual desire in surgically menopausal women: a randomized trial
Buster, J. E., Kingsberg, S. A., Aguirre, O., Brown, C., Breaux, J. G., Buch, A., Rodenberg, C. A., Wekselman, K., & Casson, P. (2005) · Obstetrics & Gynecology · doi:10.1097/01.aog.0000158103.27672.0d · Cited by 433
The relationship between testosterone levels and cognitive ability patterns
GOUCHIE, C., & Kimura, D. (1991) · Psychoneuroendocrinology · doi:10.1016/0306-4530(91)90018-o · Cited by 423
The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women.
Morales, A. J., Haubrich, R. H., Hwang, J. Y., Asakura, H., & Yen, S. S. C. (1998) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1998.00507.x · Cited by 418
Hysterectomy, Oophorectomy, and Endogenous Sex Hormone Levels in Older Women: The Rancho Bernardo Study
Laughlin, G. A., Barrett-Connor, E. L., Kritz‐Silverstein, D. C., & von Mühlen, D. G. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.2.6405 · Cited by 381
Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology.
Labrie, F., Bélanger, A., Cusan, L., & Candas, B. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.8.4161 · Cited by 350
A Prospective Longitudinal Study of Serum Testosterone, Dehydroepiandrosterone Sulfate, and Sex Hormone-Binding Globulin Levels through the Menopause Transition
Burger, H. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.8.2832 · Cited by 347
Are changes in sexual functioning during midlife due to aging or menopause?
Dennerstein, L., Dudley, E., & Burger, H. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(01)01978-1 · Cited by 345
The DSM diagnostic criteria for hypoactive sexual desire disorder in women
Brotto, L. A. (2010) · Archives of Sexual Behavior · doi:10.1007/s10508-009-9543-1 · Cited by 312 · cited 1×
“This diagnosis includes the presence of both reduced interest in sexual activity and absent arousal from external sexual/erotic cues (163–165).”
Androgen therapy in women: An Endocrine Society clinical practice guideline
Wierman, M. E., Basson, R., Davis, S. R., Khosla, S., Miller, K. K., Rosner, W., & Santoro, N. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1121 · Cited by 301 · cited 3×
“Subsequent to our 2006 guideline (5), an additional clinical study used mass spectrometry-based methods to measure Table 1.”
MethodInfluentialSelf-citation
Long-term consequences of polycystic ovary syndrome: Results of a 31 year follow-up study
Wild, S. H., Pierpoint, T., Jacobs, H. S., & McKeigue, P. (2000) · Human Fertility · doi:10.1080/1464727002000198781 · Cited by 301
Transdermal testosterone therapy improves well-being, mood, and sexual function in premenopausal women
Goldstat, R., Briganti, E. M., Tran, J., Wolfe, R. S., & Davis, S. R. (2003) · Menopause The Journal of The North American Menopause Society · doi:10.1097/01.gme.0000060256.03945.20 · Cited by 299
Self-citation
Testosterone patch for the treatment of hypoactive sexual desire disorder in naturally menopausal women
Shifren, J. L., Davis, S. R., Moreau, M., Waldbaum, A. S., Bouchard, C., Derogatis, L. R., Derzko, C. M., Bearnson, P., Kakos, N., O’Neill, S., et al. (2006) · Menopause The Journal of The North American Menopause Society · doi:10.1097/01.gme.0000243567.32828.99 · Cited by 298
Self-citation
Prevalence of Low Sexual Desire and Hypoactive Sexual Desire Disorder in a Nationally Representative Sample of US Women
West, S. L. (2008) · Archives of Internal Medicine · doi:10.1001/archinte.168.13.1441 · Cited by 294
Hysterectomy and Sexual Functioning
Rhodes, J. (1999) · JAMA · doi:10.1001/jama.282.20.1934 · Cited by 293
Brain levels of sex steroid hormones in men and women during normal aging and in Alzheimer's disease
Rosario, E. R., Chang, L., Head, E. H., Stanczyk, F. Z., & Pike, C. J. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.04.008 · Cited by 289
Time Course of Effects of Testosterone Administration on Sexual Arousal in Women
Tuiten, A., Van Honk, J., Koppeschaar, H., Bernaards, C., Thijssen, J., & Verbaten, R. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.2.149 · Cited by 288
Ovarian Androgen Production in Postmenopausal Women
Fogle, R. H., Stanczyk, F. Z., Zhang, X., & Paulson, R. J. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0581 · Cited by 286
Liquid Chromatography–Tandem Mass Spectrometry Assay for Androstenedione, Dehydroepiandrosterone, and Testosterone with Pediatric and Adult Reference Intervals
Kushnir, M. M., Blamires, T. L., Rockwood, A. L., Roberts, W. L., Yue, B., Erdogan, E., Bunker, A. M., & Meikle, A. W. (2010) · Clinical Chemistry · doi:10.1373/clinchem.2010.143222 · Cited by 286
Sexual functioning and practices in a multi‐ethnic study of midlife women: Baseline results from swan
Cain, V. S., Johannes, C. B., Avis, N. E., Mohr, B. A., Schocken, M., Skurnick, J., & Ory, M. G. (2003) · The Journal of Sex Research · doi:10.1080/00224490309552191 · Cited by 285
Comparison of oral estrogens and estrogens plus androgen on bone mineral density, menopausal symptoms, and lipid-lipoprotein profiles in surgical menopause
WATTS, N., Notelovitz, M., CHRYSTIETIMMONS, M., ALLENADDISON, W., Wiita, B., & DOWNEY, L. (1995) · Obstetrics and Gynecology · doi:10.1016/0029-7844(94)00448-m · Cited by 270
The menopausal transition: a 9-year prospective population-based study. The Melbourne Women's Midlife Health Project
Guthrie, J., Dennerstein, L., Taffe, J., Lehert, P., & Burger, H. (2004) · Climacteric · doi:10.1080/13697130400012163 · Cited by 266
Advantages and challenges of mass spectrometry assays for steroid hormones
Stanczyk, F. Z., & Clarke, N. J. (2010) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2010.05.001 · Cited by 265
Adipokines: implications for female fertility and obesity
Mitchell, M., Armstrong, D. T., Robker, R. L., & Norman, R. J. (2005) · Reproduction · doi:10.1530/rep.1.00521 · Cited by 262
Effect of oophorectomy on circulating testosterone and androstenedione levels in patients with endometrial cancer.
Judd, H. L., Lucas, W. E., & Yen, S. S. C. (1974) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(74)90490-6 · Cited by 261
Chronic anovulation syndrome and associated neoplasia.
Coulam, C. B., Annegers, J. F., & Kranz, J. S. (1983) · PubMed · Cited by 255
Endogenous Estradiol and Testosterone Levels Are Associated with Cognitive Performance in Older Women and Men
Wolf, O. T., & Kirschbaum, C. (2002) · Hormones and Behavior · doi:10.1006/hbeh.2002.1770 · Cited by 253
Correlates of Circulating Androgens in Mid-Life Women: The Study of Women’s Health Across the Nation
Santoro, N., Torréns, J. I., Crawford, S. L., Allsworth, J. E., Finkelstein, J. S., Gold, E. B., Korenman, S. G., Lasley, W. L., Luborsky, J. L., McConnell, D. S., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-2063 · Cited by 251
Self-citation
Efficacy and safety of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: a randomized, placebo-controlled trial
Davis, S. R., van der Mooren, M. J., van Lunsen, R. H. W., Lopes, P., Ribot, J., Rees, M., Moufarege, A., Rodenberg, C., Buch, A., & Purdie, D. W. (2006) · Menopause · doi:10.1097/01.gme.0000179049.08371.c7 · Cited by 250
Self-citation
Testosterone for peri and postmenopausal women
Somboonporn, W., Bell, R. J., & Davis, S. R. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004509.pub2 · Cited by 248
Self-citation
Reexamination of testosterone, dihydrotestosterone, estradiol and estrone levels across the menstrual cycle and in postmenopausal women measured by liquid chromatography-tandem mass spectrometry
Rothman, M. S., Carlson, N. E., Xu, M., Wang, C., Swerdloff, R., Lee, P., Goh, V. H. H., Ridgway, E. C., & Wierman, M. E. (2011) · Steroids · doi:10.1016/j.steroids.2010.10.010 · Cited by 248
Self-citation
Toward Excellence in Testosterone Testing: A Consensus Statement
Rosner, W., & Vesper, H. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-1314 · Cited by 248
Self-citation
Effects of oral dehydroepiandrosterone on bone density in young women with anorexia nervosa: a randomized trial.
Gordon, C. M., Grace, E., Emans, S., Feldman, H. A., Goodman, E., Becker, K. A., Rosen, C. J., Gundberg, C., & Leboff, M. (2002) · Journal of Clinical Endocrinology and Metabolism · doi:10.1097/01.ogx.0000058680.18516.da · Cited by 242
Effects of Oral Dehydroepiandrosterone on Bone Density in Young Women with Anorexia Nervosa: A Randomized Trial
Gordon, C. M., Grace, E., Emans, S. J., Feldman, H. A., Goodman, E., Becker, K. A., Rosen, C. J., Gundberg, C. M., & LeBoff, M. S. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020545 · Cited by 233
Endogenous Levels of Dehydroepiandrosterone Sulfate, but Not Other Sex Hormones, Are Associated with Depressed Mood in Older Women: The Rancho Bernardo Study
Barrett-Connor, E. L., von Mühlen, D. G., Laughlin, G. A., & Kripke, A. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb01590.x · Cited by 231
Evaluation of health-related quality of life in patients with Cushing's syndrome with a new questionnaire
Webb, S. M., Badia, X. C., Barahona, M. J., Colao, A. A. L., Strasburger, C. J., Tabarin, A., van Aken, M. O., Pivonello, R., Stalla, G. K., Lamberts, S. W. J., et al. (2008) · European Journal of Endocrinology · doi:10.1530/eje-07-0762 · Cited by 228
A single administration of testosterone improves visuospatial ability in young women
Aleman, A., Bronk, E., Kessels, R. P. C., Koppeschaar, H. P. F., & van Honk, J. (2003) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(03)00089-1 · Cited by 225
Effects of Testosterone Replacement in Androgen-Deficient Women with Hypopituitarism: A Randomized, Double-Blind, Placebo-Controlled Study
Miller, K. K., Biller, B. M. K., Beauregard, C., Lipman, J. G., Jones, J., Schoenfeld, D., Sherman, J. C., Swearingen, B., Loeffler, J. S., & Klibanski, A. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-2596 · Cited by 223
Self-citation
The Postmenopausal Ovary Is Not a Major Androgen-Producing Gland
Couzinet, B., Méduri, G., Lecce, M. G., Young, J., Brailly, S., Loosfelt, H., Milgröm, E., & SCHAISON, G. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.10.7900 · Cited by 219
Testosterone Effects on the Breast: Implications for Testosterone Therapy for Women
Somboonporn, W., & Davis, S. R. (2004) · Endocrine Reviews · doi:10.1210/er.2003-0016 · Cited by 217
Self-citation
Total Testosterone Assays in Women with Polycystic Ovary Syndrome: Precision and Correlation with Hirsutism
Legro, R. S., Schlaff, W. D., Diamond, M. P., Coutifaris, C., Casson, P. R., Brzyski, R. G., Christman, G. M., Trussell, J. C., Krawetz, S. A., Snyder, P. J., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-1123 · Cited by 213
Self-citation
Testosterone Therapy in Women With Chronic Heart Failure
Iellamo, F., Volterrani, M., Caminiti, G., Karam, R., Massaro, R., Fini, M., Collins, P. D., & Rosano, G. M. C. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.03.090 · Cited by 212
Long-term impaired quality of life in Cushing's syndrome despite initial improvement after surgical remission
Lindsay, J. R., Nansel, T., Baid, S., Gumowski, J., & Nieman, L. K. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1058 · Cited by 210
Addition of dehydroepiandrosterone (DHEA) for poor-responder patients before and during IVF treatment improves the pregnancy rate: A randomized prospective study
Wiser, A., Gonen, O., Ghetler, Y., Shavit, T., Berkovitz, A., & Shulman, A. (2010) · Human Reproduction · doi:10.1093/humrep/deq220 · Cited by 207
Estradiol and testosterone in specific regions of the human female brain in different endocrine states
Bixo, M., Ba¨ckstro¨m, T., Winblad, B. G., & Andersson, A. (1995) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(95)00179-4 · Cited by 205
Oral dehydroepiandrosterone for adrenal androgen replacement: pharmacokinetics and peripheral conversion to androgens and estrogens in young healthy females after dexamethasone suppression
Arlt, W., Justl, H.-G., Callies, F., Reincke, M., Hübler, D., Oettel, M., Ernst, M., Schulte, H. M., & Allolio, B. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.6.4850 · Cited by 199
Self-citation
Sex Differences in Endocrine and Psychological Responses to Psychosocial Stress in Healthy Elderly Subjects and the Impact of a 2-Week Dehydroepiandrosterone Treatment1
Kudielka, B. M., Hellhammer, J., Hellhammer, D. H., Wolf, O. T., Pirke, K., Váradi, E., Pilz, J., & Kirschbaum, C. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.5.4758 · Cited by 196
Low sexual desire in midlife and older women: personality factors, psychosocial development, present sexuality
Hartmann, U. H., Philippsohn, S., Heiser, K., & Rüffer-Hesse, C. (2004) · Menopause The Journal of The North American Menopause Society · doi:10.1097/01.gme.0000143705.42486.33 · Cited by 196
The Use of a Sensitive Equilibrium Dialysis Method for the Measurement of Free Testosterone Levels in Healthy, Cycling Women and in Human Immunodeficiency Virus-Infected Women1
Sinha‐Hikim, I., Arver, S., Beall, G. N., Shen, R., Guerrero, M., Sattler, F. R., Shikuma, C., Nelson, J. C., Landgren, B.-M., Mazer, N. A., et al. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.4.4718 · Cited by 192
Postmenopausal plasma sex hormone levels and breast cancer risk over 20 years of follow-up
Zhang, X., Tworoger, S. S., Eliassen, A. H., & Hankinson, S. E. (2013) · Breast Cancer Research and Treatment · doi:10.1007/s10549-012-2391-z · Cited by 190
Serum steroid profiling by isotopic dilution-liquid chromatography–mass spectrometry: Comparison with current immunoassays and reference intervals in healthy adults
Fanelli, F., Belluomo, I., Lallo, V. D. D., Cuomo, G., IASIO, R. D., Baccini, M., Casadio, E., Casetta, B., Vicennati, V., Gambineri, A., et al. (2010) · Steroids · doi:10.1016/j.steroids.2010.11.005 · Cited by 190
A novel spreadsheet method for calculating the free serum concentrations of testosterone, dihydrotestosterone, estradiol, estrone and cortisol: With illustrative examples from male and female populations
Mazer, N. A. (2009) · Steroids · doi:10.1016/j.steroids.2009.01.008 · Cited by 189
Age-Specific Reference Ranges for Serum Testosterone and Androstenedione Concentrations in Women Measured by Liquid Chromatography-Tandem Mass Spectrometry
Haring, R., Hannemann, A., John, U., Radke, D., Nauck, M., Wallaschofski, H., Owen, L., Adaway, J., Keevil, B. G., & Brabant, G. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-2134 · Cited by 185
Evidence That Parenteral Testosterone Therapy May Improve Endothelium-Dependent and -Independent Vasodilation in Postmenopausal Women Already Receiving Estrogen
Worboys, S., Kotsopoulos, D., Teede, H. J., McGrath, B. P., & Davis, S. R. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.1.7103 · Cited by 181
Self-citation
Sexual disabilities are not singularities
Fugl-Meyer, K. S., & Fugl‐Meyer, A. R. (2002) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3900914 · Cited by 179
Predictive accuracy and sources of variability in calculated free testosterone estimates
Sartorius, G., Ly, L. P., Sikaris, K., McLachlan, R., & Handelsman, D. J. (2009) · Annals of Clinical Biochemistry: International Journal of Laboratory Medicine · doi:10.1258/acb.2008.008171 · Cited by 175
Postmenopausal dehydroepiandrosterone administration increases free insulin-like growth factor-I and decreases high-density lipoprotein: a six-month trial
Casson, P. R., Santoro, N. F., Elkind-Hirsch, K. E., Carson, S. A., Hornsby, P. J., Abraham, G. E., & Buster, J. E. (1998) · Fertility and Sterility · doi:10.1016/s0015-0282(98)00121-6 · Cited by 174
Self-citation
Testosterone treatment of HSDD in naturally menopausal women: the ADORE study
Panay, N., Al‐Azzawi, F., Bouchard, C., Davis, S. R., Eden, J., Lodhi, I., REES, M. C. P., Rodenberg, C. A., RYMER, J. M., Schwenkhagen, A., et al. (2010) · Climacteric · doi:10.3109/13697131003675922 · Cited by 173
Self-citation
ORIGINAL ARTICLE: Accuracy of calculated free testosterone formulae in men
Ly, L. P., Sartorius, G., Hull, L., Leung, A., Swerdloff, R. S., Wang, C., & Handelsman, D. J. (2010) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2010.03804.x · Cited by 172
Effects of DHEA replacement on bone mineral density and body composition in elderly women and men
Villareal, D. T., Holloszy, J. O., & Kohrt, W. M. (2000) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2000.01131.x · Cited by 169
Testosterone Concentrations in Women Aged 25–50 Years: Associations with Lifestyle, Body Composition, and Ovarian Status
Sowers, M., Beebe, J. L., McConnell, D. S., Randolph, J. F., & Jannausch, M. L. (2001) · American Journal of Epidemiology · doi:10.1093/aje/153.3.256 · Cited by 168
Differential Effects of Oral Estrogen versus Oral Estrogen-Androgen Replacement Therapy on Body Composition in Postmenopausal Women
Dobs, A. S., Nguyen, T., Pace, C., & Roberts, C. P. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.4.8362 · Cited by 168
A two-year, double-blind comparison of estrogen-androgen and conjugated estrogens in surgically menopausal women. Effects on bone mineral density, symptoms and lipid profiles.
Barrett-Connor, E. L., Young, R. L., Notelovitz, M., Sullivan, J., Wiita, B., Yang, H. M., & Nolan, J. C. (1999) · PubMed · Cited by 167
The Relation Between Mood and Sexuality in Gay Men
Bancroft, J., Janssen, E., Strong, D., & Vukadinovic, Z. (2003) · Archives of Sexual Behavior · doi:10.1023/a:1023461500810 · Cited by 167
Effects of estradiol with and without testosterone on body composition and relationships with lipids in postmenopausal women
Davis, S. R., Walker, K., & Strauss, B. J. (2000) · Menopause The Journal of The North American Menopause Society · doi:10.1097/00042192-200011000-00005 · Cited by 167
Self-citation
Effects of Risedronate and Low-Dose Transdermal Testosterone on Bone Mineral Density in Women with Anorexia Nervosa: A Randomized, Placebo-Controlled Study
Miller, K. K., Meenaghan, E. M., Lawson, E. A., Misra, M., Gleysteen, S., Schoenfeld, D., Herzog, D. B., & Klibanski, A. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-0380 · Cited by 160
Self-citation
Topical Testosterone for Breast Cancer Patients with Vaginal Atrophy Related to Aromatase Inhibitors: A Phase I/II Study
Witherby, S. M., Johnson, J. V., Demers, L. M., Mount, S. L., Littenberg, B., MacLean, C. D., Wood, M. E., & Muss, H. B. (2011) · The Oncologist · doi:10.1634/theoncologist.2010-0435 · Cited by 160
Biotransformation of Oral Dehydroepiandrosterone in Elderly Men: Significant Increase in Circulating Estrogens
Arlt, W., Haas, J., Callies, F., Reincke, M., Hübler, D., Oettel, M., Ernst, M. E., Schulte, H. M., & Allolio, B. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.6.5789 · Cited by 156
Self-citation
Endogenous Androgens and Carotid Intimal-Medial Thickness in Women
BERNINI, G. P., Sgrò, M., Moretti, A., Argenio, G. F., BARLASCINI, C. O., Cristofani, R., & Salvetti, A. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.6.5824 · Cited by 156
Interlaboratory comparison study of serum total testoserone measurements performed by mass spectrometry methods
Vesper, H. W., Bhasin, S., Wang, C., Tai, S. S., Dodge, L. A., Singh, R. J., Nelson, J., Ohorodnik, S., Clarke, N. J., Salameh, W. A., et al. (2009) · Steroids · doi:10.1016/j.steroids.2009.01.004 · Cited by 152
Combined Estrogen and Testosterone Use and Risk of Breast Cancer in Postmenopausal Women
Tamimi, R. M., Hankinson, S. E., Chen, W. Y., ROSNER, B. A., & Colditz, G. A. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.14.1483 · Cited by 150
Impact of Oral Contraceptives on Sex Hormone-Binding Globulin and Androgen Levels: A Retrospective Study in Women with Sexual Dysfunction
Panzer, C., Wise, S., Fantini, G. V., Kang, D., Munarriz, R. M., Guay, A. T., & Goldstein, I. (2006) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2005.00198.x · Cited by 150
A systematic review and meta-analysis of randomized placebo-controlled trials of DHEA treatment effects on quality of life in women with adrenal insufficiency
Alkatib, A. A., Cosma, M., Elamin, M. B., Erickson, D., Swiglo, B. A., Erwin, P. J., & Montori, V. M. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0672 · Cited by 147 · cited 1×
“In 2009, a meta-analysis of 10 studies concluded that DHEA therapy in adrenal insufficiency may result in small improvements in health-related quality of life and depression, but it had no effects on anxiety or sexual well-being (142).”
Wide distribution of the serum dehydroepiandrosterone and sex steroid levels in postmenopausal women: role of the ovary?
Labrie, F., Martel, C., & Balser, J. (2011) · Menopause · doi:10.1097/gme.0b013e3181e195a6 · Cited by 143
Safety and Efficacy of a Testosterone Metered-Dose Transdermal Spray for Treating Decreased Sexual Satisfaction in Premenopausal Women
Davis, S. R., Papalia, M.-A., Norman, R. J., O'Neill, S., Redelman, M., Williamson, M., Stuckey, B. G. A., Wlodarczyk, J., Gard'ner, K., & Humberstone, A. (2008) · Annals of Internal Medicine · doi:10.7326/0003-4819-148-8-200804150-00001 · Cited by 143
Self-citation
The use of androgens or androgen-modulating agents in poor responders undergoing in vitro fertilization: a systematic review and meta-analysis
Bosdou, J. K., Venetis, C. A., Kolibianakis, E. M., Toulis, K. A., Goulis, D. G., Zepiridis, L., & Tarlatzis, B. C. (2012) · Human Reproduction Update · doi:10.1093/humupd/dmr051 · Cited by 141
Extremes of Endogenous Testosterone Are Associated with Increased Risk of Incident Coronary Events in Older Women
Laughlin, G. A., Vivian Goodell, A., & Barrett-Connor, E. L. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1693 · Cited by 140
A Prospective Study of Dehydroepiandrosterone Sulfate and Cognitive Function in an Older Population: The Rancho Bernardo Study
Barrett-Connor, E. L., & Edelstein, S. L. (1994) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1994.tb07491.x · Cited by 137
Evaluation of Adverse Outcome in Young Women with Polycystic Ovary Syndrome Versus Matched, Reference Controls: A Retrospective, Observational Study
Morgan, C. L., Jenkins-Jones, S., Currie, C. J., & Rees, D. A. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-1690 · Cited by 136
Transdermal Testosterone Administration in Women with Acquired Immunodeficiency Syndrome Wasting: A Pilot Study
Miller, K. K., Corcoran, C. P., Armstrong, C. A., Caramelli, K. E., Anderson, E. J., Cotton, D. J., Basgoz, N. O., Hirschhorn, L. R., TUOMALA, R. E., Schoenfeld, D., et al. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.8.5051 · Cited by 136
Self-citation
Endocrine activity of the postmenopausal ovary: the effects of pituitary down-regulation and oophorectomy
Sluijmer, A. V., Heineman, M. J., de Jong, F. H., & Evers, J. L. H. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.7.7608272 · Cited by 134
Dynamics of serum testosterone during the menstrual cycle evaluated by daily measurements with an ID-LC–MS/MS method and a 2nd generation automated immunoassay
Bui, H. N., Sluss, P. M., Blincko, S. J., Knol, D. L., Blankenstein, M. A., & Heijboer, A. C. (2012) · Steroids · doi:10.1016/j.steroids.2012.10.010 · Cited by 134
Does oral contraceptive-induced reduction in free testosterone adversely affect the sexuality or mood of women?
Graham, C. A., Bancroft, J., Doll, H., Greco, T., & Tanner, A. E. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2006.12.011 · Cited by 133
Simultaneous Measurement of Serum Testosterone and Dihydrotestosterone by Liquid Chromatography–Tandem Mass Spectrometry
Shiraishi, S., Lee, P. W. N., Leung, A., Goh, V. H. H., Swerdloff, R. S., & Wang, C. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2008.103846 · Cited by 132
Calculation of Bioavailable and Free Testosterone in Men: A Comparison of 5 Published Algorithms
de Ronde, W., van der Schouw, Y. T., Pols, H. A., Gooren, L. J., Muller, M., Grobbee, D. E., & de Jong, F. H. (2006) · Clinical Chemistry · doi:10.1373/clinchem.2005.063354 · Cited by 131
Androgens in Women with Anorexia Nervosa and Normal-Weight Women with Hypothalamic Amenorrhea
Miller, K. K., Lawson, E. A., Mathur, V. A., Wexler, T., Meenaghan, E. M., Misra, M., Herzog, D. B., & Klibanski, A. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2501 · Cited by 130
Self-citation
Psychological Reactions and Sexual Life after Hysterectomy with and without Oophorectomy
Nathorst‐Böös, J., & von Schoultz, B. (2010) · Gynecologic and Obstetric Investigation · doi:10.1159/000292735 · Cited by 127
Breast cancer incidence in postmenopausal women using testosterone in addition to usual hormone therapy
Dimitrakakis, C., Jones, R. A., Liu, A., & Bondy, C. A. (2004) · Menopause The Journal of The North American Menopause Society · doi:10.1097/01.gme.0000119983.48235.d3 · Cited by 127
The Use of a Sensitive Equilibrium Dialysis Method for the Measurement of Free Testosterone Levels in Healthy, Cycling Women and in Human Immunodeficiency Virus-Infected Women
Sinha‐Hikim, I. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.83.4.1312 · Cited by 126
Postmenopausal breast cancer risk in relation to sex steroid hormones, prolactin and SHBG (Sweden)
Manjer, J., Johansson, R., Berglund, G. L., Janzon, L., Kaaks, R., Ågren, Å., & Lenner, P. (2003) · Cancer Causes & Control · doi:10.1023/a:1025671317220 · Cited by 125
Dehydroepiandrosterone combined with exercise improves muscle strength and physical function in frail older women
Kenny, A. M., Boxer, R. S., Kleppinger, A., Brindisi, J., Feinn, R., & Burleson, J. A. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.03019.x · Cited by 125
Effects of testosterone administration on selective aspects of object-location memory in healthy young women
Postma, A., Meyer, G., Tuiten, A., van Honk, J., Kessels, R. P. C., & Thijssen, J. H. H. (2000) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(00)00010-x · Cited by 124
Sex Hormone Levels, Breast Cancer Risk, and Cancer Receptor Status in Postmenopausal Women: the ORDET Cohort
Sieri, S., Krogh, V., BOLELLI, G., Abagnato, C. A., Grioni, S., Pala, V. M., Evangelista, A., Allemani, C., Micheli, A., Tagliabue, G., et al. (2009) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-0808 · Cited by 123
LETTER TO THE EDITOR: An Extraordinarily Inaccurate Assay for Free Testosterone Is Still with Us
Rosner, W. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.6.7643 · Cited by 123
Self-citation
Androgen Deficiency in Women with Hypopituitarism1
Miller, K. K., Sesmilo, G., Schiller, A., Schoenfeld, D., Burton, S., & Klibanski, A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.2.7246 · Cited by 117
Self-citation
OPPOSING EFFECTS OF DHEA REPLACEMENT IN ELDERLY SUBJECTS ON DECLARATIVE MEMORY AND ATTENTION AFTER EXPOSURE TO A LABORATORY STRESSOR
Wolf, O. T., Kudielka, B. M., Hellhammer, D. H., Hellhammer, J., & Kirschbaum, C. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00032-8 · Cited by 116
Standardization of testosterone measurements in humans
Vesper, H. W., & Botelho, J. C. (2010) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2010.03.032 · Cited by 113
The psychophysiology of sex
(2008) · Choice Reviews Online · doi:10.5860/choice.45-5270 · Cited by 113
Polycystic Ovaries and the Risk of Breast Cancer
Gammon, M. D., & Thompson, W. D. (1991) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116156 · Cited by 113
The DSM Diagnostic Criteria for Female Orgasmic Disorder
Graham, C. A. (2009) · Archives of Sexual Behavior · doi:10.1007/s10508-009-9542-2 · Cited by 112
Effect of low-dose oral contraceptives on androgenic markers and acne
Thorneycroft, I. H., Stanczyk, F. Z., Bradshaw, K. D., Ballagh, S. A., Nichols, M. D. N., & Weber, M. E. (1999) · Contraception · doi:10.1016/s0010-7824(99)00093-1 · Cited by 112
Women’s Motivations for Sex: Exploring the Diagnostic and Statistical Manual, Fourth Edition, Text Revision Criteria for Hypoactive Sexual Desire and Female Sexual Arousal Disorders
Carvalheira, A. A., Brotto, L. A., & Leal, I. M. P. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01693.x · Cited by 110
Dehydroepiandrosterone Sulfate Levels Are Associated with More Favorable Cognitive Function in Women
Davis, S. R., Shah, S. M., McKenzie, D. P., Kulkarni, J., Davison, S. L., & Bell, R. J. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-2128 · Cited by 109
Self-citation
Effects of Dehydroepiandrosterone Replacement Therapy on Bone Mineral Density in Older Adults: A Randomized, Controlled Trial
Jankowski, C. M., Gozansky, W. S., Schwartz, R. S., Dahl, D. J., Kittelson, J. M., Scott, S., Pelt, R. E. V., & Kohrt, W. M. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-2484 · Cited by 109
Circulating Steroid Hormone Levels and Risk of Breast Cancer for Postmenopausal Women
Baglietto, L., Severi, G., English, D. R., Krishnan, K., Hopper, J. L., McLean, C., Morris, H. A., Tilley, W. D., & Giles, G. G. (2010) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-09-0532 · Cited by 108
Testosterone Administration in Women with Anorexia Nervosa
Miller, K. K., Grieco, K. A., & Klibanski, A. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1181 · Cited by 108
Self-citation
Sex Hormone Levels and Risks of Estrogen Receptor-Negative and Estrogen Receptor-Positive Breast Cancers
Farhat, G. N., Cummings, S. R., Chlebowski, R. T., Parimi, N., Cauley, J. A., Rohan, T. E., Huang, A. J., Vitolins, M. Z., Hubbell, F. A., Manson, J. E., et al. (2011) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djr031 · Cited by 107
A prospective study of 3 years of outcomes after hysterectomy with and without oophorectomy
Farquhar, C. M., Harvey, S. A., Yu, Y., Sadler, L. C., & Stewart, A. W. (2006) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.08.066 · Cited by 105
Effect of dehydroepiandrosterone supplementation on bone mineral density, bone markers, and body composition in older adults: the DAWN trial
von Mühlen, D. G., Laughlin, G. A., Kritz‐Silverstein, D. C., Bergstrom, J., & Bettencourt, R. (2007) · Osteoporosis International · doi:10.1007/s00198-007-0520-z · Cited by 101
Surgical menopause
Shifren, J. L., & Avis, N. E. (2007) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e318032c505 · Cited by 101
Placebo-controlled trial of dehydroepiandrosterone (DHEA) for treatment of nonmajor depression in patients with HIV/AIDS.
Rabkin, J., McElhiney, M., Rabkin, R., McGrath, P., & Ferrando, S. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.1.59 · Cited by 101
Role of androgens in women's sexual dysfunction
Basson, R. J., Brotto, L. A., Petkau, A. J., & Labrie, F. (2010) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e3181d59765 · Cited by 100
Self-citation
Dehydroepiandrosterone (DHEA) supplementation for cognitive function in healthy elderly people
Evans, J. G., Malouf, R. S., Huppert, F. A., & van Niekerk, J. K. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006221 · Cited by 99
Serum total and unbound testosterone and sex hormone binding globulin (SHBG) in female acne patients treated with two different oral contraceptives
Palatsi, R., Hirvensalo, E., Liukko, P., Malmiharju, T., Mattila, L., Riihiluoma, P., & Ylöstalo, P. (1984) · Acta Dermato-Venereologica · doi:10.2340/0001555564517523 · Cited by 98
Relationship of Volumetric Bone Density and Structural Parameters at Different Skeletal Sites to Sex Steroid Levels in Women
Khosla, S., Riggs, B. L., Robb, R. A., Camp, J. J., Achenbach, S. J., Oberg, A. L., Rouleau, P. A., & Melton, L. J. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0396 · Cited by 98
DHEA-S Levels and Cardiovascular Disease Mortality in Postmenopausal Women: Results from the National Institutes of Health—National Heart, Lung, and Blood Institute (NHLBI)-Sponsored Women’s Ischemia Syndrome Evaluation (WISE)
Shufelt, C., Bretsky, P., Almeida, C. M., Johnson, B. D., Shaw, L. J., Azziz, R., Braunstein, G. D., Pepine, C. J., Bittner, V., Vido, D. A., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-0143 · Cited by 97
The Benefits and Harms of Systemic Dehydroepiandrosterone (DHEA) in Postmenopausal Women With Normal Adrenal Function: A Systematic Review and Meta-analysis
Elraiyah, T., Sonbol, M. B., Wang, Z., Khairalseed, T., Asi, N., Undavalli, C., Nabhan, M., Altayar, O., Prokop, L., Montori, V. M., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-2261 · Cited by 97
Self-citation
Perimenopausal androgen decline after oophorectomy does not influence sexuality or psychological well-being
Aziz, A., Brännström, M., Bergquist, C., & Silfverstolpe, G. (2005) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.12.008 · Cited by 94
Hypoactive sexual desire disorder in postmenopausal women
Nappi, R. E., Wawra, K., & Schmitt, S. (2006) · Gynecological Endocrinology · doi:10.1080/09513590600762265 · Cited by 92
Effects of Dehydroepiandrosterone Supplementation on Cognitive Function and Quality of Life: The DHEA and Well‐Ness (DAWN) Trial
Kritz‐Silverstein, D. C., von Mühlen, D. G., Laughlin, G. A., & Bettencourt, R. (2008) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2008.01768.x · Cited by 91
Original Research—Endocrinology: A Comparative Study of the Effects of Local Estrogen With or Without Local Testosterone on Vulvovaginal and Sexual Dysfunction in Postmenopausal Women
Raghunandan, C., Agrawal, S., Dubey, P., Choudhury, M., & Jain, A. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01667.x · Cited by 90
The effect of gonadal and adrenal steroid therapy on skeletal health in adolescents and young women with anorexia nervosa
DiVasta, A. D., Feldman, H. A., Giancaterino, C., Rosen, C. J., LeBoff, M. S., & Gordon, C. M. (2012) · Metabolism · doi:10.1016/j.metabol.2011.11.016 · Cited by 90
Reproductive Hormones and Obesity: 9 Years of Observation From the Study of Women's Health Across the Nation
Sutton-Tyrrell, K., Zhao, X., Santoro, N. F., Lasley, B. L., Sowers, M., Johnston, J. M., Mackey, R. H., & Matthews, K. A. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq049 · Cited by 90
Self-citation
Adiponectin and Its Receptors in the Ovary: Further Evidence for a Link between Obesity and Hyperandrogenism in Polycystic Ovary Syndrome
Comim, F. V., Hardy, K., & Franks, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080416 · Cited by 89
Testosterone levels and cognitive functioning in women with polycystic ovary syndrome and in healthy young women
Schattmann, L., & Sherwin, B. B. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.02.007 · Cited by 89
The Benefits and Harms of Systemic Testosterone Therapy in Postmenopausal Women With Normal Adrenal Function: A Systematic Review and Meta-analysis
Elraiyah, T. A., Sonbol, M. B., Wang, Z., Khairalseed, T., Asi, N., Undavalli, C., Nabhan, M., Firwana, B., Altayar, O., Prokop, L. J., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-2262 · Cited by 88
Self-citation
Testosterone Reference Ranges in Normally Cycling Healthy Premenopausal Women
Braunstein, G. D., Reitz, R. E., Buch, A., Schnell, D., & Caulfield, M. P. (2011) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2011.02380.x · Cited by 85
Serum Dehydroepiandrosterone Sulfate in Cushing's Syndrome*
YAMAJI, T., Ishibashi, M., Sekihara, H., Itabashi, A., & Yanaihara, T. (1984) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-59-6-1164 · Cited by 85
Change to Either a Nonandrogenic or Androgenic Progestin-Containing Oral Contraceptive Preparation is Associated with Improved Sexual Function in Women with Oral Contraceptive-Associated Sexual Dysfunction
Davis, S. R., Bitzer, J., Giraldi, A. G. E., Palacios, S., Parke, S., Serrani, M., Mellinger, U., & Nappi, R. E. (2013) · The Journal of Sexual Medicine · doi:10.1111/jsm.12310 · Cited by 84
Self-citation
Androgen Deficiency in Women with Hypopituitarism
Miller, K. K. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.2.561 · Cited by 83
Self-citation
Endogenous Sex Hormones, Breast Cancer Risk, and Tamoxifen Response: An Ancillary Study in the NSABP Breast Cancer Prevention Trial (P-1)
Beattie, M. S., Costantino, J. P., Cummings, S. R., Wickerham, D. L., Vogel, V. G., Dowsett, M., Folkerd, E. J., Willett, W. C., Wolmark, N., & Hankinson, S. E. (2006) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djj011 · Cited by 81
Androgens regulate neprilysin expression: role in reducing β‐amyloid levels
Yao, M., Nguyen, T. V., Rosario, E. R., Ramsden, M., & Pike, C. J. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05341.x · Cited by 80
Endogenous testosterone and endothelial function in postmenopausal women
Montalcini, T., Gorgone, G., Gazzaruso, C., Sesti, G., Perticone, F., & Pujia, A. (2006) · Coronary Artery Disease · doi:10.1097/01.mca.0000236290.79306.d1 · Cited by 80
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Givens, J. R., Andersen, R. N., Wiser, W. L., Umstot, E. S., & Fish, S. A. (1976) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(76)90089-2 · Cited by 79
Sex Differences in Endocrine and Psychological Responses to Psychosocial Stress in Healthy Elderly Subjects and the Impact of a 2-Week Dehydroepiandrosterone Treatment
Kudielka, B. M. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.83.5.1756 · Cited by 76
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Naessén, T., Sjogren, U., Bergquist, J., Larsson, M., Lind, L., & Kushnir, M. M. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1722 · Cited by 75
Effects of Testosterone Replacement in Human Immunodeficiency Virus-Infected Women with Weight Loss
Choi, H., Gray, P. B., Storer, T. W., Calof, O. M., Woodhouse, L. J., Singh, A. B., Padero, C., Mac, R. P., Sinha‐Hikim, I., Shen, R., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1677 · Cited by 75
Transdermal Testosterone Administration in Women with Acquired Immunodeficiency Syndrome Wasting: A Pilot Study
Miller, K. K. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.83.8.2717 · Cited by 75
Self-citation
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Brito, J. P., Domecq, J. P., Murad, M. H., Guyatt, G. H., & Montori, V. M. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1814 · Cited by 74
Self-citation
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Wildman, R. P., Tepper, P. G., Crawford, S., Finkelstein, J. S., Sutton-Tyrrell, K., Thurston, R. C., Santoro, N. F., Sternfeld, B., & Greendale, G. A. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-1614 · Cited by 73
Self-citation
Dehydroepiandrosterone Replacement in Women With Adrenal Insufficiency
Arlt, W., Callies, F., van Vlijmen, J. C., Koehler, I., Reincke, M., Bidlingmaier, M., Huebler, D., Oettel, M., Ernst, M. E., Schulte, H. M., et al. (2000) · Obstetrical & Gynecological Survey · doi:10.1097/00006254-200003000-00022 · Cited by 73
Self-citation
Prospective case-control study of premenopausal serum estradiol and testosterone levels and breast cancer risk
Dorgan, J. F., Stanczyk, F. Z., Kahle, L., & Brinton, L. A. (2010) · Breast Cancer Research · doi:10.1186/bcr2779 · Cited by 72
Validation of 5 routine assays for serum free testosterone with a candidate reference measurement procedure based on ultrafiltration and isotope dilution–gas chromatography–mass spectrometry
Van Uytfanghe, K., Stöckl, D., Kaufman, J. M., Fiers, T., De Leenheer, A., & Thienpont, L. M. (2005) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2004.12.001 · Cited by 71
Desire emerges from excitement: A psychophysiological perspective on sexual motivation
Both, S., Everaerd, W. T. A. M., Laan, E. T. M., & Janssen, E. (2007) · UvA-DARE (University of Amsterdam) · Cited by 70
Circulating Dehydroepiandrosterone Sulfate Concentrations during the Menopausal Transition
Crawford, S. L., Santoro, N., Laughlin, G. A., Sowers, M. F., McConnell, D. S., Sutton-Tyrrell, K., Weiss, G., Vuga, M., Randolph, J. F., & Lasley, B. L. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0386 · Cited by 70
Self-citation
Effects of dehydroepiandrosterone supplement on health-related quality of life in glucocorticoid treated female patients with systemic lupus erythematosus
Nordmark, G., Bengtsson, C., Larsson, A. O., Karlsson, F. A., Sturfelt, G. K., & Rönnblom, L. (2005) · Autoimmunity · doi:10.1080/08916930500285550 · Cited by 70
The association of plasma androgen levels with breast, ovarian and endometrial cancer risk factors among postmenopausal women
Danforth, K. N., Eliassen, A. H., Tworoger, S. S., Missmer, S. A., Barbieri, R. L., ROSNER, B. A., Colditz, G. A., & Hankinson, S. E. (2009) · International Journal of Cancer · doi:10.1002/ijc.24709 · Cited by 70
Low-dose Transdermal Testosterone Augmentation Therapy Improves Depression Severity in Women
Miller, K. K., Perlis, R. H., Papakostas, G. I., Mischoulon, D., Iosifescu, D. V., Brick, D. J., & D, M. F. M. (2009) · CNS Spectrums · doi:10.1017/s1092852900023944 · Cited by 70
Self-citation
Endogenous androgen levels and cardiovascular risk profile in women across the adult life span
Bell, R. J., Davison, S. L., Papalia, M.-A., McKenzie, D. P., & Davis, S. R. (2007) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e31802b6cb1 · Cited by 69
Self-citation
Androgen replacement therapy in Turner syndrome: a pilot study
Zuckerman-Levin, N., Frolova-Bishara, T., Militianu, D., Levin, M., Aharon-Peretz, J., & Hochberg, Z. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0514 · Cited by 69
A cardiovascular safety study of LibiGel (testosterone gel) in postmenopausal women with elevated cardiovascular risk and hypoactive sexual desire disorder
White, W. B., Grady, D. G., Giudice, L. C., Berry, S. M., Zborowski, J., & Snabes, M. C. (2011) · American Heart Journal · doi:10.1016/j.ahj.2011.09.021 · Cited by 68
The Association of Plasma DHEA and DHEA Sulfate with Breast Cancer Risk in Predominantly Premenopausal Women
Tworoger, S. S., Missmer, S. A., Eliassen, A. H., Spiegelman, D. L., Folkerd, E. J., Dowsett, M., Barbieri, R. L., & Hankinson, S. E. (2006) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0976 · Cited by 67
Adrenal Function in Hirsutism. II. Effect of an Oral Contraceptive*
Wild, R. A., Umstot, E. S., Andersen, R. N., & Givens, J. R. (1982) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-54-4-676 · Cited by 67
Safety and Efficacy of a Testosterone Patch for the Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women: a Randomized, Placebo-Controlled Trial
Braunstein, G. D., Sundwall, D. A., Katz, M., Shifren, J. L., Buster, J. E., Simon, J. A., Bachman, G., Aguirre, O., Lucas, J. D., Rodenberg, C. A., et al. (2006) · The Journal of Urology · doi:10.1016/s0022-5347(05)00380-0 · Cited by 67
Dehydroepiandrosterone replacement therapy in older adults: 1- and 2-y effects on bone
Weiss, E. P., Shah, K. N., Fontana, L., Lambert, C. P., Holloszy, J. O., & Villareal, D. T. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.27265 · Cited by 66
Obesity, Adipokines and Metabolic Syndrome in Polycystic Ovary Syndrome
Carmina, E. (2012) · Frontiers of hormone research · doi:10.1159/000341840 · Cited by 64
Predictors of Sexual Desire Disorders in Women
Brotto, L. A., Petkau, A. J., Labrie, F., & Basson, R. (2011) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2010.02146.x · Cited by 64
Self-citation
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Teplin, V., Vittinghoff, E., Lin, F., Learman, L. A., Richter, H. E., & Kuppermann, M. (2007) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000252700.03133.8b · Cited by 64
Accuracy of calculated free testosterone differs between equations and depends on gender and SHBG concentration
Hackbarth, J. S., Hoyne, J. B., Grebe, S. K. G., & Singh, R. (2010) · Steroids · doi:10.1016/j.steroids.2010.08.008 · Cited by 62
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Couzinet, B. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.10.5060 · Cited by 59
Analog-Based Free Testosterone Test Results Linked to Total Testosterone Concentrations, Not Free Testosterone Concentrations
Fritz, K. S., McKean, A. J. S., Nelson, J. C., & Wilcox, R. B. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2007.094870 · Cited by 58
Differential expression of apoptosis receptors on diffuse and intestinal type stomach carcinoma
Vollmers, H. P., D�mmrich, J., Hensel, F., Ribbert, H., Meyer‐Bahlburg, A., Ufken-Gaul, T., Korff, M. V., & M�ller-Hermelink, H. K. (1997) · Cancer · doi:10.1002/(sici)1097-0142(19970201)79:3 · Cited by 57
The safety of 52 weeks of oral DHEA therapy for postmenopausal women
Panjari, M., Bell, R. J., Jane, F., Adams, J., Morrow, C., & Davis, S. R. (2009) · Maturitas · doi:10.1016/j.maturitas.2009.03.020 · Cited by 56
Self-citation
Premenopausal serum androgens and breast cancer risk: a nested case-control study
Zeleniuch‐Jacquotte, A., Afanasyeva, Y., Kaaks, R., Rinaldi, S., Scarmo, S., Liu, M., Arslan, A. A., Toniolo, P. G., Shore, R. E., & Koenig, K. L. (2012) · Breast Cancer Research · doi:10.1186/bcr3117 · Cited by 56
A randomized trial of the effect of testosterone and estrogen on verbal fluency, verbal memory, and spatial ability in healthy postmenopausal women
Kočoska-Maraš, L., Zethraeus, N., Rådestad, A. F., Ellingsen, T., von Schoultz, B., Johannesson, M., & Hirschberg, A. L. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.05.062 · Cited by 55
Increases in Bone Mineral Density in Response to Oral Dehydroepiandrosterone Replacement in Older Adults Appear to Be Mediated by Serum Estrogens
Jankowski, C. M., Gozansky, W. S., Kittelson, J. M., Pelt, R. E. V., Schwartz, R. S., & Kohrt, W. M. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-2614 · Cited by 55
Postmenopausal Estrogen-Containing Hormone Therapy and the Risk of Breast Cancer
Jick, S. S., Hagberg, K. W., Kaye, J. A., & Jick, H. (2009) · Obstetrics and Gynecology · doi:10.1097/aog.0b013e31818fdde4 · Cited by 55
Endogenous sex hormone levels in postmenopausal women undergoing carotid artery endarterectomy
Debing, E., Peeters, E., Duquet, W., Poppe, K. G., Velkeniers, B., & den Brande, P. V. (2007) · European Journal of Endocrinology · doi:10.1530/eje-06-0702 · Cited by 55
Differential Effects of Oral Estrogen versus Oral Estrogen-Androgen Replacement Therapy on Body Composition in Postmenopausal Women
Dobs, A. S. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.87.4.1509 · Cited by 54
The Prevalence of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women: An Epidemiological Study of Women in Four European Countries
Graziottin, A., Koochaki, P. E., Rodenberg, C. A., & Dennerstein, L. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01319.x · Cited by 52
Genital and Subjective Measurement of the Time Course Effects of an Acute Dose of Testosterone vs. Placebo in Postmenopausal Women
Heard-Davison, A., Heiman, J. R., & Kuffel, S. W. (2007) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2006.00406.x · Cited by 50

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6 of the 257 references couldn’t be matched to a known paper.

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[13]13. Braunstein GD, Reitz RE, Buch A, Schnell D, Caulfield MP. Tes- tosterone reference ranges in normally cycling healthy premeno- pausal women. J Sex Med. 2011;8:2924 -2934.
[28]28. Ly LP, Sartorius G, Hull L, et al. Accuracy of calculated free tes- tosterone formulae in men. Clin Endocrinol (Oxf). 2010;73:382- 388.
[31]31. Rosner W. An extraordinarily inaccurate assay for free testoster- one is still with us. J Clin Endocrinol Metab. 2001;86:2903.
[179]179. Rhodes JC, Kjerulff KH, Langenberg PW, Guzinski GM. Hyster- ectomy and sexual functioning. JAMA. 1999;282:1934 -1941.
[182]182. Snabes MC, Zborowski J, Simes S. Libigel (testosterone gel) does not differentiate from placebo therapy in the treatment of hypo- active sexual desire in postmenopausal women. J Sex Med. 2012; 3:171.
[195]195. Anderson KE, Sellers TA, Chen PL, Rich SS, Hong CP, Folsom AR. Association of Stein-Leventhal syndrome with the incidence of postmenopausal breast carcinoma in a large prospective study of women in Iowa. Cancer. 1997;79:494 -499.

Sorted by citations

2016 IMS Recommendations on women’s midlife health and menopause hormone therapy
Baber, R., Panay, N., & Fenton, A. J. (2016) · Climacteric · doi:10.3109/13697137.2015.1129166 · Cited by 968
Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline
Fleseriu, M., Hashim, I. A., Karavitaki, N., Melmed, S., Murad, M. H., Salvatori, R., & Samuels, M. H. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-2118 · Cited by 945
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The Menopause Transition: Signs, Symptoms, and Management Options
Santoro, N. F., Roeca, C. M., Peters, B. A., & Neal-Perry, G. S. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa764 · Cited by 774
Self-citation
Long-term health consequences of premature or early menopause and considerations for management
Faubion, S. S., Kuhle, C. L., Shuster, L. T., & Rocca, W. A. (2015) · Climacteric · doi:10.3109/13697137.2015.1020484 · Cited by 566
Hormone replacement therapy in young women with primary ovarian insufficiency and early menopause
Sullivan, S. D., Sarrel, P. M., & Nelson, L. M. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2016.09.046 · Cited by 519

See all 363

Authors: Wierman, M. E., Arlt, W., Basson, R., Davis, S. R., Miller, K. K., Murad, M. H., Rosner, W., & Santoro, N.
Affiliations: University of British Columbia (CA)
University of Birmingham (GB)
Veterans Health Administration (US)
Massachusetts General Hospital (US)
Mayo Clinic (US)
ORCID: Wierman, Margaret E.
Arlt, Wiebke
Basson, Rosemary
Davis, Susan R.
Miller, Karen K.
Murad, Mohammad H.
Santoro, Nanette
Venue: The Journal of Clinical Endocrinology & Metabolism
Publisher: The Endocrine Society
Published: 2014-10
Volume: 99
Issue: 10
Pages: 3489-3510
ISSN: 0021-972X (ISSN-L)
1945-7197
DOI: 10.1210/jc.2014-2260
OpenAlex: W2169638329
Semantic Scholar: 0ab9fec7488d4092d18727dbe6ea5d548da84c6e
Cited by: 363
References: 257
Citations by year: 2026: 18 · 2025: 24 · 2024: 27 · 2023: 22 · 2022: 52 · 2021: 46 · 2020: 28 · 2019: 25 · 2018: 31 · 2017: 27 · 2016: 34 · 2015: 25 · 2014: 3
FWCI: 23.88
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
PubMed (publishedVersion)
University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
Spiral (Imperial College London) (submittedVersion, cc-by-nc-nd)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
Keywords: androgen therapy, women, testosterone, dehydroepiandrosterone, hypoactive sexual desire disorder, postmenopausal women, adrenal insufficiency, hypopituitarism, surgical menopause, hyperandrogenism, infertility, sexual dysfunction, bone health, cardiovascular risk, treatment safety
MeSH terms: Contraindications, Androgens, Endocrinology, Female, Humans, Hypopituitarism, Societies, Medical, Practice Guidelines as Topic, Evidence-Based Medicine, Hormone Replacement Therapy

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Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline

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