Cited by 10,986Multidisciplinary Science and Engineering ResearchStatistical Methods in EpidemiologyReliability and Agreement in Measurement

Correlation Coefficients: Appropriate Use and Interpretation

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Schober, Patrick, Boer, Christa, Schwarte, Lothar A.·2018·Anesthesia & Analgesia

Abstract

Correlation in the broadest sense is a measure of an association between variables. In correlated data, the change in the magnitude of 1 variable is associated with a change in the magnitude of another variable, either in the same (positive correlation) or in the opposite (negative correlation) direction. Most often, the term correlation is used in the context of a linear relationship between 2 continuous variables and expressed as Pearson product-moment correlation. The Pearson correlation coefficient is typically used for jointly normally distributed data (data that follow a bivariate normal distribution). For nonnormally distributed continuous data, for ordinal data, or for data with relevant outliers, a Spearman rank correlation can be used as a measure of a monotonic association. Both correlation coefficients are scaled such that they range from -1 to +1, where 0 indicates that there is no linear or monotonic association, and the relationship gets stronger and ultimately approaches a straight line (Pearson correlation) or a constantly increasing or decreasing curve (Spearman correlation) as the coefficient approaches an absolute value of 1. Hypothesis tests and confidence intervals can be used to address the statistical significance of the results and to estimate the strength of the relationship in the population from which the data were sampled. The aim of this tutorial is to guide researchers and clinicians in the appropriate use and interpretation of correlation coefficients.

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Authors
Schober, P., Boer, C., & Schwarte, L. A.
Affiliations
Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
Corresponding author
Schober, Patrick
Venue
Anesthesia & Analgesia
Published
2018-05
Volume
126
Issue
5
Pages
1763-1768
ISSN
0003-2999 (ISSN-L)
OpenAlex
W2793350103
Cited by
10,986
References
25
Citations by year
2026: 2053 · 2025: 2301 · 2024: 2029 · 2023: 1611 · 2022: 1417 · 2021: 926 · 2020: 486 · 2019: 128 · 2018: 17 · 2017: 1 · 2012: 2
FWCI
297.60
Type
journal article
Language
en
Open access
Locations
  • Anesthesia & Analgesia (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Topics
  • Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Multidisciplinary Science and Engineering Research
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
  • Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Reliability and Agreement in Measurement
Keywords
correlation coefficient, Pearson correlation, Spearman correlation, linear association, bivariate normal distribution, non-normal data, ordinal data, outliers, hypothesis testing, confidence intervals, statistical interpretation
MeSH terms
Correlation of Data, Data Collection, Data Interpretation, Statistical, Humans, Statistics, Nonparametric

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